{"id":57370,"date":"2023-03-01T16:52:40","date_gmt":"2023-03-01T21:52:40","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=57370"},"modified":"2025-10-22T19:45:07","modified_gmt":"2025-10-22T23:45:07","slug":"phentermine-side-effects","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/phentermine-side-effects\/","title":{"rendered":"Phentermine side effects and how to avoid them"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Being <\/span><a href=\"https:\/\/www.cdc.gov\/obesity\/index.html\"><span style=\"font-weight: 400;\">overweight or obese<\/span><\/a><span style=\"font-weight: 400;\"> is a common and major public health problem in the United States. Both conditions are associated with an increased risk of certain types of cancer, Type 2 diabetes, cardiovascular disease, and other serious conditions that contribute to a reduced quality of life. When a modified calorie diet and exercise alone fail in weight-loss attempts, healthcare providers may suggest adding a weight-loss prescription medicine.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Phentermine hydrochloride is a prescription-only appetite suppressant, also known as an anorectic, approved by the U.S. Food and Drug Administration (FDA) for short-term use for weight loss. It works by stimulating specific chemicals in the brain that tell the body it is full. Phentermine is a Schedule IV <\/span><span style=\"font-weight: 400;\">controlled substance<\/span><span style=\"font-weight: 400;\">, which means it may have the potential for abuse leading to psychological or physical dependence. The most common brand names for phentermine are <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/adipex-p\"><span style=\"font-weight: 400;\">Adipex-P<\/span><\/a><span style=\"font-weight: 400;\"> and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/lomaira\"><span style=\"font-weight: 400;\">Lomaira<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">As with any medication, it is important to be aware of <\/span><span style=\"font-weight: 400;\">adverse effects<\/span><span style=\"font-weight: 400;\"> and drug interactions before beginning therapy. The following information highlights potential phentermine side effects and how to avoid them.<\/span><\/p>\n<p><b>Related: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/phentermine-alternatives\/\"><b>Phentermine alternatives<\/b><\/a><b> | <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/where-can-i-get-phentermine\/\"><b>Where can I get phentermine?<\/b><\/a><\/p>\n<h2 id=\"common-side-effects-of-phentermine\"><span style=\"font-weight: 400;\">Common side effects of phentermine<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The most <\/span><a href=\"https:\/\/online.epocrates.com\/drugs\/6105\/phentermine-hydrochloride\/Adverse-Reactions\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">common side effects<\/span><\/a><span style=\"font-weight: 400;\"> of phentermine include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Rapid or irregular heartbeat<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Elevated blood pressure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Restlessness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Insomnia<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Feelings of euphoria<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Feelings of dissatisfaction or anxiety (dysphoria)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tremor<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Headache<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dry mouth<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Unpleasant taste<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diarrhea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Constipation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Itching<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Impotence<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Libido changes<\/span><\/li>\n<\/ul>\n<h2 id=\"serious-side-effects-of-phentermine\"><span style=\"font-weight: 400;\">Serious side effects of phentermine<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The following list includes rare but serious side effects of phentermine:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Decreased blood flow to the heart (cardiac ischemia)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Rapid beating of the heart (tachycardia)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High blood pressure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pulmonary hypertension<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heart failure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Psychosis<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Physical or psychological dependence<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Withdrawal symptoms if abruptly discontinued<\/span><\/li>\n<\/ul>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/phentermine-for-weight-loss\/\"><b>Is phentermine for weight loss safe?<\/b><\/a><\/p>\n<h3 id=\"phentermine-and-primary-pulmonary-hypertension\"><span style=\"font-weight: 400;\">Phentermine and primary pulmonary hypertension<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Weight-control drugs, including phentermine, have been linked to a rare but serious, adverse effect known as <\/span><a href=\"https:\/\/www.hopkinsmedicine.org\/health\/conditions-and-diseases\/primary-pulmonary-hypertension\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">primary pulmonary hypertension<\/span><\/a><span style=\"font-weight: 400;\"> (PPH). PPH is high blood pressure in the arteries of the lungs. Symptoms of PPH may include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Blue lips and skin\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Chest pressure or pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness or fainting spells\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Rapid pulse or pounding heartbeat<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fatigue<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Shortness of breath (dyspnea)<\/span><\/li>\n<\/ul>\n<h3 id=\"phentermine-and-valvular-heart-disease\"><span style=\"font-weight: 400;\">Phentermine and valvular heart disease<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">There have been rare reports of <\/span><a href=\"https:\/\/www.hopkinsmedicine.org\/health\/conditions-and-diseases\/heart-valve-diseases\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">valvular heart disease<\/span><\/a><span style=\"font-weight: 400;\"> in people who have taken phentermine, particularly when paired with fenfluramine, a formerly popular combination drug called \u201cphen-fen\u201d that was discontinued in 1997. Valvular heart disease involves damage to one or more of the heart valves. Symptoms of valvular heart disease may include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Chest pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Palpitations caused by irregular heartbeats<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fatigue<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low or high blood pressure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Shortness of breath<\/span><\/li>\n<\/ul>\n<h3 id=\"phentermine-and-risk-of-abuse\"><span style=\"font-weight: 400;\">Phentermine and risk of abuse<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Phentermine is a Schedule IV <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/controlled-substances-act\/\"><span style=\"font-weight: 400;\">controlled substance<\/span><\/a><span style=\"font-weight: 400;\">, meaning it carries a risk of abuse and dependence. It is chemically and pharmacologically similar to amphetamines and other stimulant drugs that are subject to abuse. Because it is a stimulant, it can be abused to create a high, particularly when taken in large doses. Phentermine is considered safe when taken as prescribed by a healthcare professional.<\/span><\/p>\n<h2 id=\"how-soon-do-phentermine-side-effects-start\"><span style=\"font-weight: 400;\">How soon do phentermine side effects start?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Many of the most commonly experienced side effects of phentermine occur when initiating therapy but should begin to lessen once the body adjusts to the drug. Less common but more serious side effects, including heart problems, such as primary pulmonary hypertension or valvular heart disease, are typically associated with longer-term use or taking higher than prescribed doses.\u00a0<\/span><\/p>\n<h2 id=\"how-long-do-phentermine-side-effects-last\"><span style=\"font-weight: 400;\">How long do phentermine side effects last?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The recommended duration of the therapy with phentermine is three to six weeks, with a maximum of three months, and the more commonly experienced side effects should end when the medication is stopped, if not sooner as the body adjusts to the medicine.<\/span><\/p>\n<h2 id=\"what-are-the-long-term-side-effects-of-phentermine\"><span style=\"font-weight: 400;\">What are the long-term side effects of phentermine?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Although the FDA-approved use of phentermine is for no longer than three months, there is <\/span><a href=\"https:\/\/www.sciencedaily.com\/releases\/2019\/03\/190322105747.htm\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">clinical evidence<\/span><\/a><span style=\"font-weight: 400;\"> to support that the use of phentermine for longer-term therapy may be safe and effective. The study found that those who used phentermine for longer than three months did not have increased cardiovascular adverse effects such as high blood pressure or an increased risk of heart attack, stroke, or death.\u00a0<\/span><\/p>\n<h2 id=\"phentermine-contraindications\"><span style=\"font-weight: 400;\">Phentermine contraindications<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">You should not use phentermine if you have any of the following <\/span><a href=\"https:\/\/online.epocrates.com\/drugs\/6103\/phentermine-hydrochloride\/Contraindications-Cautions\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">conditions<\/span><\/a><span style=\"font-weight: 400;\">:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">History of cardiovascular disease (e.g., coronary artery disease, stroke, arrhythmias, congestive heart failure, uncontrolled hypertension)<\/span><\/li>\n<\/ul>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Within 14 days of taking a monoamine oxidase inhibitor\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/hypothyroidism-treatment-and-medications\"><span style=\"font-weight: 400;\">Hyperthyroidism<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/glaucoma-treatment-and-medications\"><span style=\"font-weight: 400;\">Glaucoma<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Agitated state<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">History of drug abuse<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Are pregnant, trying to become pregnant, or breastfeeding<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Have a known allergy to any active or inactive ingredients\u00a0<\/span><\/li>\n<\/ul>\n<h2 id=\"phentermine-warnings\"><span style=\"font-weight: 400;\">Phentermine warnings<\/span><\/h2>\n<h3 id=\"children-and-adolescents\"><span style=\"font-weight: 400;\">Children and adolescents<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The safety and effectiveness of phentermine in pediatric patients have not been established. Because obesity in children is considered a chronic condition requiring longer-term treatment, the use of phentermine, which is only approved for short-term therapy, is not recommended.<\/span><\/p>\n<h3 id=\"seniors\"><span style=\"font-weight: 400;\">Seniors<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Dose selection of phentermine in older adults should start at the low end of the dosing range due to the greater likelihood of decreased liver, kidney, or cardiac function and of concomitant disease or other drug therapy. Phentermine is mainly excreted by the kidney, and the risk of side effects may be particularly greater in older patients who have decreased kidney function.<\/span><\/p>\n<h3 id=\"pregnancy-and-breastfeeding\"><span style=\"font-weight: 400;\">Pregnancy and breastfeeding<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Phentermine is contraindicated during pregnancy because weight loss is not recommended for pregnant women and may result in fetal harm. It is not known if phentermine is present in human milk; therefore, it is not recommended to breastfeed while taking the medication. A woman\u2019s healthcare provider is the best source of information for medical advice when managing weight-loss treatment while breastfeeding.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/safe-medication-during-pregnancy\/\"><b>What medications are safe to take during pregnancy?<\/b><\/a><\/p>\n<h3 id=\"overdose\"><span style=\"font-weight: 400;\">Overdose<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Management of phentermine overdose is largely symptomatic. If an overdose is suspected, a healthcare professional should be contacted immediately. Commonly reported adverse reactions associated with phentermine overdose include:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Restlessness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tremor<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Overactive or over-responsive bodily reflexes (hyperreflexia)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Rapid respiration<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Confusion<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Aggressive behavior<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hallucinations<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Panic attacks<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cardiovascular effects include:\u00a0<\/span>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Irregular heartbeat<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">High or low blood pressure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Failure of blood circulation<\/span><\/li>\n<\/ul>\n<\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Gastrointestinal symptoms include:\u00a0<\/span>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Nausea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Vomiting<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Diarrhea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Abdominal cramps<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h3 id=\"withdrawal-symptoms\"><span style=\"font-weight: 400;\">Withdrawal symptoms<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Long-term use of phentermine may cause physical and psychological dependence. Abrupt discontinuation after prolonged use may result in withdrawal symptoms including:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Excessive drowsiness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fatigue<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tremors<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Depression<\/span><\/li>\n<\/ul>\n<h3 id=\"effect-on-the-ability-to-engage-in-potentially-hazardous-tasks\"><span style=\"font-weight: 400;\">Effect on the ability to engage in potentially hazardous tasks<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Taking phentermine may impair the ability to engage in potentially hazardous activities by slowing motor skills and affecting vision. Do not drive a car or operate heavy machinery until you know how phentermine affects you.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\t\t<div class=\"singlecare-dynamic-newsletter-wrapper sin-newsletter-wrapper\">\n\t\t\t<span class=\"heading\">Get our weight management newsletter<\/span>\n\t\t\t<form class=\"form-wrapper\" data-newsletter-form=\"1\" data-subsource=\"Weight Management Newsletter\">\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<label for=\"dynamic-email\">Email<\/label>\n\t\t\t\t\t<input type=\"email\" id=\"dynamic-email\" class=\"email\" required>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<input class=\"submit-form-btn\" type=\"submit\" value=\"Click to sign up\">\n\t\t\t\t<\/div>\n\t\t\t<\/form>\n\t\t\t<p class=\"success-message\" aria-live=\"polite\"><\/p>\n\t\t<\/div>\n\t<\/span><\/p>\n<h2 id=\"phentermine-interactions\"><span style=\"font-weight: 400;\">Phentermine interactions<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The following have the potential to cause drug interactions when taken at the same time as phentermine:<\/span><\/p>\n<h3 id=\"monoamine-oxidase-inhibitors\">Monoamine oxidase inhibitors<\/h3>\n<p><span style=\"font-weight: 400;\">Use of phentermine is contraindicated within 14 days of taking a <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/maois\"><span style=\"font-weight: 400;\">monoamine oxidase inhibitor (MAOI)<\/span><\/a><span style=\"font-weight: 400;\"> such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.<\/span><\/p>\n<h3 id=\"alcohol\">Alcohol<\/h3>\n<p><span style=\"font-weight: 400;\">Concomitant use of alcohol with phentermine may result in an adverse drug reaction more severe than taking phentermine alone. For example, phentermine side effects can include heart-related symptoms like increased heart rate and high blood pressure. These side effects can worsen when mixing alcohol and phentermine.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/phentermine-and-caffeine\/\"><b>Is it safe to mix phentermine and caffeine?<\/b><\/a><\/p>\n<h3 id=\"insulin-and-antidiabetic-medications\">Insulin and antidiabetic medications<\/h3>\n<p><span style=\"font-weight: 400;\">Phentermine may affect blood sugar levels in people with diabetes mellitus. A reduction in insulin or oral diabetes medications may be required.<\/span><\/p>\n<h3 id=\"adrenergic-neuron-blocking-medications\"><strong>Adrenergic neuron-blocking<\/strong> medications<\/h3>\n<p><span style=\"font-weight: 400;\">Adrenergic neuron-blocking drugs, although rarely used anymore, may be prescribed to treat high blood pressure or psychotic symptoms. Phentermine may decrease the blood pressure-lowering effect of these drugs.<\/span><\/p>\n<h2 id=\"how-to-avoid-phentermine-side-effects\"><span style=\"font-weight: 400;\">How to avoid phentermine side effects<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Phentermine should only be used by those with a <\/span><a href=\"https:\/\/www.health.harvard.edu\/blog\/how-useful-is-the-body-mass-index-bmi-201603309339\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">body mass index<\/span><\/a><span style=\"font-weight: 400;\"> (BMI) of 30 or greater, or a BMI of over 27 for those with other medical conditions such as controlled hypertension, high cholesterol, or diabetes. The following steps will help reduce the likelihood of experiencing side effects:\u00a0<\/span><\/p>\n<h3 id=\"1-talk-to-your-healthcare-professional-about-your-health-history\"><span style=\"font-weight: 400;\">1. Talk to your healthcare professional about your health history<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Before starting phentermine, tell your healthcare professional if you have, or have had, any of the following conditions:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Abnormal heart rhythms<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Arteriosclerosis (hardening of the arteries)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/congestive-heart-failure-treatment-and-medications\"><span style=\"font-weight: 400;\">Congestive heart failure<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Drug abuse or dependence<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heart or blood vessel disease\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High blood pressure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hyperthyroidism\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stroke.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heart valve disease\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pulmonary hypertension<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kidney disease<\/span><\/li>\n<\/ul>\n<h3 id=\"2-give-your-provider-a-full-list-of-the-medications-you-re-taking\"><span style=\"font-weight: 400;\">2. Give your provider a full list of the medications you\u2019re taking<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Tell your healthcare professional about all of the medications you are currently taking, including prescription drugs, over-the-counter medicines, vitamins, and herbal supplements.<\/span><\/p>\n<h3 id=\"3-avoid-alcohol\"><span style=\"font-weight: 400;\">3. Avoid alcohol<\/span><\/h3>\n<p><a href=\"https:\/\/www.singlecare.com\/blog\/tag\/alcohol-interactions\/\">Alcohol<\/a> may increase the risk of serious interactions and side effects, such as chest pain and raised blood pressure, and can reduce the effectiveness of phentermine.<\/p>\n<h3 id=\"4-follow-directions\"><span style=\"font-weight: 400;\">4.<\/span><span style=\"font-weight: 400;\">Follow directions<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Take phentermine exactly as directed by your healthcare professional. Do not take more than the prescribed dosage amount, as this may increase the risk of side effects.<\/span><\/p>\n<h2 id=\"how-to-treat-side-effects-of-phentermine\"><span style=\"font-weight: 400;\">How to treat side effects of phentermine<\/span><\/h2>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Unless otherwise directed by your healthcare professional, phentermine should be taken first thing in the morning on an empty stomach, allowing it to be effective throughout the day and making it easier to fall asleep at night.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">It is important to stay <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/benefits-of-drinking-water\/\"><span style=\"font-weight: 400;\">hydrated<\/span><\/a><span style=\"font-weight: 400;\"> when using phentermine. Because it may cause dry mouth, dehydration may make it worse. Try to drink 8 to 12 glasses of water a day to stay hydrated.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Contact your healthcare professional if you experience any of the following:<\/span>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Any decrease in the amount of exercise you are normally able to tolerate<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Accidental overdose<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Increase in <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/blood-pressure-levels\/\"><span style=\"font-weight: 400;\">blood pressure<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Any side effects that bother you or do not go away<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Being overweight or obese is a common and major public health problem in the United States. Both conditions are associated with an increased risk of certain types of cancer, Type 2 diabetes, cardiovascular disease, and other serious conditions that contribute to a reduced quality of life. When a modified calorie diet and exercise alone fail [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":57385,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[10298,12752],"coauthors":[20733],"class_list":["post-57370","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-diabetes","tag-medication-side-effects","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Phentermine side effects and how to avoid them | SingleCare<\/title>\n<meta name=\"description\" content=\"Rapid or irregular heartbeat, elevated blood pressure, and restlessness are common phentermine side effects. 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