{"id":57532,"date":"2023-03-14T09:30:13","date_gmt":"2023-03-14T13:30:13","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=57532"},"modified":"2024-11-12T19:46:47","modified_gmt":"2024-11-13T00:46:47","slug":"does-benadryl-raise-blood-pressure","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/does-benadryl-raise-blood-pressure\/","title":{"rendered":"Does Benadryl raise your blood pressure?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">If you\u2019ve had allergies, hives, hay fever, or the common cold then it\u2019s likely you\u2019ve considered <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/benadryl-allergynadryl-itch-relief\"><span style=\"font-weight: 400;\">Benadryl<\/span><\/a><span style=\"font-weight: 400;\"> to treat your symptoms. It\u2019s an <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/taking-antihistamines-daily\/\"><span style=\"font-weight: 400;\">oral antihistamine<\/span><\/a><span style=\"font-weight: 400;\"> that is very effective to help alleviate symptoms like itchy, watery eyes, sneezing, and runny nose. However, it\u2019s an older medication that can come with some unpleasant side effects\u2014like major drowsiness or dry mouth. But, if you have hypertension, does Benadryl raise your blood pressure? Experts offer advice.<\/span><\/p>\n<h2 id=\"how-does-benadryl-work\"><span style=\"font-weight: 400;\">How does Benadryl work<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Benadryl (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/diphenhydramine-hcl\"><span style=\"font-weight: 400;\">diphenhydramine<\/span><\/a><span style=\"font-weight: 400;\">) is a first-generation antihistamine sold over the counter. Like other antihistamines, it works by blocking histamine receptors. Histamine is a chemical in your body that responds to allergens.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cBenadryl suppresses the effects of histamine by blocking its action on a variety of target organs including blood vessels, respiratory airways, and smooth muscles,\u201d says Dung Trinh, MD, an expert in preventive health and inflammation and founder of <\/span><a href=\"https:\/\/www.healthybrainclinic.com\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Healthy Brain Clinic<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Because Benadryl can make you feel sleepier than newer allergy treatments, it is more often used to treat an allergic reaction, hives, or viral symptoms whereas second- and third-generation medications like <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/zyrtec\"><span style=\"font-weight: 400;\">Zyrtec<\/span><\/a><span style=\"font-weight: 400;\"> (cetirizine), <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/claritin\"><span style=\"font-weight: 400;\">Claritin<\/span><\/a><span style=\"font-weight: 400;\"> (loratadine), and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/allegra-allergy\"><span style=\"font-weight: 400;\">Allegra<\/span><\/a><span style=\"font-weight: 400;\"> (fexofenadine) are generally used to treat or prevent daily allergy symptoms. Benadryl is also sometimes used to prevent motion sickness or to help with nausea.<\/span><\/p>\n<h2 id=\"does-benadryl-affect-blood-pressure\"><span style=\"font-weight: 400;\">Does Benadryl affect blood pressure?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">\u201cMost antihistamines, including Benadryl, do not have much effect on your blood pressure,\u201d says <\/span><a href=\"https:\/\/www.roswellskin.com\/brandon-cometti-md\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Brandon Cometti<\/span><\/a><span style=\"font-weight: 400;\">, MD, a dermatologist at Roswell Skin Center in New Mexico<\/span><span style=\"font-weight: 400;\">. \u201cAn antihistamine might react with other medications or other underlying health issues and lead to lower blood pressure, but this is usually not the case.\u201d When taken along with blood pressure medications (such as propranolol or metoprolol), Benadryl may cause your blood pressure to dip <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/low-blood-pressure\/\"><span style=\"font-weight: 400;\">too low<\/span><\/a><span style=\"font-weight: 400;\">. Be sure to discuss any pre-existing medical conditions and current medications with a healthcare professional to rule out any potential drug interactions.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cResearch studies have shown that patients taking Benadryl may experience a decrease in their blood pressure readings, which may cause symptoms of dizziness and increase the risk of falls,\u201d Dr. <\/span><span style=\"font-weight: 400;\">Trinh says.\u00a0<\/span><\/p>\n<h3 id=\"benadryl-side-effects\"><span style=\"font-weight: 400;\">Benadryl side effects<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">In addition to dizziness and impaired coordination, other common <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK526010\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">side effects<\/span><\/a><span style=\"font-weight: 400;\"> of Benadryl include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sleepiness or sedation\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Headache\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Constipation\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dry mouth<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Possible serious side effects include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Seizures<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Confusion<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Arrhythmias<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Anemia<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heatstroke<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">In rare cases, Benadryl can raise your heart rate\u2014but <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4112269\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">research<\/span><\/a><span style=\"font-weight: 400;\"> shows that cardiac issues are unlikely unless you use more than the <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/benadryl-allergy\/dosage\"><span style=\"font-weight: 400;\">recommended dose<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/benadryl-overdose\/\"><b>Can you overdose on Benadryl?<\/b><\/a><\/p>\n<h2 id=\"what-allergy-medicine-can-i-take-with-high-blood-pressure\"><span style=\"font-weight: 400;\">What allergy medicine can I take with high blood pressure?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">It is generally safe to take Benadryl or another antihistamine if you have high blood pressure\u2014as long as they do not contain decongestants, according to Dr. Cometti. Single-ingredient antihistamine medications are not known to raise blood pressure.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The following meds for seasonal allergies are considered safe for people with high blood pressure:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Benadryl (diphenhydramine)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Zyrtec (cetirizine)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Claritin (loratadine)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Allegra (fexofenadine)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nasal sprays including <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/flonase-sensimist\"><span style=\"font-weight: 400;\">Flonase<\/span><\/a><span style=\"font-weight: 400;\"> (fluticasone) and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/nasacort-allergy-24hr\"><span style=\"font-weight: 400;\">Nasacort<\/span><\/a><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">\t\t<div class=\"singlecare-dynamic-newsletter-wrapper sin-newsletter-wrapper\">\n\t\t\t<span class=\"heading\">Get our allergies newsletter<\/span>\n\t\t\t<form class=\"form-wrapper\" data-newsletter-form=\"1\" data-subsource=\"Allergies Newsletter\">\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<label for=\"dynamic-email\">Email<\/label>\n\t\t\t\t\t<input type=\"email\" id=\"dynamic-email\" class=\"email\" required>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<input class=\"submit-form-btn\" type=\"submit\" value=\"Click to sign up\">\n\t\t\t\t<\/div>\n\t\t\t<\/form>\n\t\t\t<p class=\"success-message\" aria-live=\"polite\"><\/p>\n\t\t<\/div>\n\t<\/span><\/p>\n<h2 id=\"what-allergy-medication-should-i-not-take-with-high-blood-pressure\"><span style=\"font-weight: 400;\">What allergy medication should I <\/span><i><span style=\"font-weight: 400;\">not<\/span><\/i><span style=\"font-weight: 400;\"> take with high blood pressure?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Not all allergy treatments are safe for people with hypertension\u2014particularly combination medications that contain decongestants and certain pain relievers.\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Decongestants:<\/b><span style=\"font-weight: 400;\"> \u201cThe two main decongestant ingredients found in most allergy, cold, and sinus medications are phenylephrine or pseudoephedrine,\u201d Dr. Cometti explains. \u201cThese are known to raise blood pressure and heart rate.\u201d Both of these ingredients should be avoided if you have high blood pressure, unless your doctor approves their use.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Nonsteroidal anti-inflammatory drugs (NSAIDs)<\/b><span style=\"font-weight: 400;\">: These drugs, which include ibuprofen, which is found in some combination medications, may raise blood pressure slightly. Ask your healthcare provider before using.\u00a0<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">The following combination medications are examples of drugs that may increase your blood pressure:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Allegra-D (fexofenadine\/pseudoephedrine)\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Zyrtec-D (cetirizine\/pseudoephedrine)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Claritin-D (loratadine\/pseudoephedrine)\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Advil Allergy and Congestion Relief (chlorpheniramine\/ibuprofen\/phenylephrine)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sudafed (pseudoephedrine)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sudafed PE (phenylephrine)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Benadryl Allergy Plus Congestion (diphenhydramine\/phenylephrine)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tylenol Cold + Flu + Cough Night (acetaminophen\/dextromethorphan\/doxylamine\/phenylephrine)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">The list above does not contain all medications that may affect your blood pressure. Before you take any medication, you should carefully read the ingredients list and seek medical advice from your healthcare provider or pharmacist.\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>If you\u2019ve had allergies, hives, hay fever, or the common cold then it\u2019s likely you\u2019ve considered Benadryl to treat your symptoms. It\u2019s an oral antihistamine that is very effective to help alleviate symptoms like itchy, watery eyes, sneezing, and runny nose. However, it\u2019s an older medication that can come with some unpleasant side effects\u2014like major [&hellip;]<\/p>\n","protected":false},"author":135,"featured_media":57361,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[554,737],"coauthors":[20598],"class_list":["post-57532","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-allergies","tag-heart-health","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Does Benadryl raise blood pressure?<\/title>\n<meta name=\"description\" content=\"Benadryl should not have much effect on your blood pressure, but when taken with blood pressure medications it may cause your blood pressure to dip too low.\" \/>\n<meta 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