{"id":57661,"date":"2023-03-27T09:30:52","date_gmt":"2023-03-27T13:30:52","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=57661"},"modified":"2024-10-25T10:48:20","modified_gmt":"2024-10-25T14:48:20","slug":"trazodone-for-dogs","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/trazodone-for-dogs\/","title":{"rendered":"How trazodone can help anxious dogs"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Just like their human best friends, dogs can feel <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/anxiety-treatment-and-medications\"><span style=\"font-weight: 400;\">anxious<\/span><\/a><span style=\"font-weight: 400;\"> and even <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/depression-treatment-and-medications\"><span style=\"font-weight: 400;\">depressed<\/span><\/a><span style=\"font-weight: 400;\"> sometimes. Also like humans, the medication <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/trazodone-hcl\"><span style=\"font-weight: 400;\">trazodone<\/span><\/a><span style=\"font-weight: 400;\"> is sometimes prescribed for dogs who aren&rsquo;t their usual happy selves. In humans, this medication treats depression and <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/insomnia-treatment-and-medications\"><span style=\"font-weight: 400;\">insomnia<\/span><\/a><span style=\"font-weight: 400;\">&mdash;thanks to its sedative effects. Here is what you should know about using this Rx in veterinary medicine, including its use, dosage, and side effects.&nbsp;<\/span><\/p>\n<h2 id=\"what-is-trazodone-used-for-in-dogs\"><span style=\"font-weight: 400;\">What is trazodone used for in dogs?<\/span><\/h2>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/trazodone-hcl\/what-is\"><span style=\"font-weight: 400;\">Trazodone<\/span><\/a><span style=\"font-weight: 400;\">, also known by its brand names Desyrel and Oleptro, is an antidepressant. It works by increasing serotonin levels in the central nervous system. For dogs, it&rsquo;s primarily used as a treatment for <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4414248\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">anxiety disorders<\/span><\/a><span style=\"font-weight: 400;\">. &ldquo;Some veterinarians will prescribe your dog a mild sedative or anti-anxiety medication if they have noise phobias, separation anxiety, or other short-term calming needs,&rdquo; says <\/span><a href=\"https:\/\/seniortailwaggers.com\/team\/dr-chyrle-bonk-dvm\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Chyrle Bonk<\/span><\/a><span style=\"font-weight: 400;\">, DVM, a veterinarian at <\/span><a href=\"https:\/\/seniortailwaggers.com\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Senior Tail Waggers<\/span><\/a><span style=\"font-weight: 400;\">.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Trazodone is a serotonin antagonist reuptake inhibitor (SARI), which means it helps your brain use the neurotransmitter serotonin correctly when you are depressed or anxious. It also has a sedative effect.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">&ldquo;Sedatives are commonly prescribed for dogs before anesthesia, for anxiety or noise phobia such as thunderstorms and fireworks,&rdquo; <\/span><a href=\"https:\/\/seniortailwaggers.com\/team\/dr-sara-ochoa\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Sara Ochoa, DVM<\/span><\/a><span style=\"font-weight: 400;\">, a veterinarian at<\/span><span style=\"font-weight: 400;\"> Senior Tail Waggers<\/span><span style=\"font-weight: 400;\">.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">&ldquo;Trazodone can [also] be used as a behavior-modifying medication. This can help make aggressive dogs more calm and easier to treat at the vet clinic or when getting groomed.&rdquo; If a medication used off-label helps your dog feel better on a day they&rsquo;d otherwise be miserable&mdash;like the Fourth of July, during a thunderstorm, for nail clippings, or before vet visits&mdash;many veterinarians and pet parents think that&rsquo;s the right move.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">However, it&rsquo;s important to note that while the drug you are prescribed is the same as the one your dog would be given, you should never give your dog trazodone without consulting your veterinarian first. You need to give your vet a complete health history so they can determine if trazodone is right for your pet and, if so, what dosage would be appropriate.&nbsp;<\/span><\/p>\n<h2 id=\"trazodone-dosage-for-dogs\"><span style=\"font-weight: 400;\">Trazodone dosage for dogs<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Trazodone comes in a short-acting or long-acting tablet and is taken with water. If needed, the medication can be compounded into a liquid for dogs and cats who have trouble taking pills. The doses range from 50 mg to 300 mg and can vary depending on body weight and the condition for which it is being prescribed. It can be used daily for more generalized anxiety or as needed in specific situations.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">&ldquo;The dose of trazodone that is correct for your dog will depend on the dog&rsquo;s weight and what conditions you&rsquo;re trying to treat,&rdquo; Dr. Bonk says. A dog who is very anxious might not seem particularly sedated on a &ldquo;usual&rdquo; dose of trazodone for their weight and may need a larger dose to make it through a medical procedure without being stressed or aggressive.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Vets recommend the following when administering trazodone:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Give trazodone with food to avoid nausea.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Administer the dose on an as-needed basis 30 minutes to an hour before the stressful event or phobia, so it has time to kick in.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Expect a couple of weeks for the medication to reach full effect for long-term uses such as separation anxiety or behavioral disorders.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Your vet will give you specifics for what to expect based on your pet&rsquo;s dose, size, and temperament. You will need to monitor your dog&rsquo;s reaction to the drug closely to see what works best for them. The desired effect of trazodone is that your pet will feel less anxious, especially in stressful situations. Hopefully, your pet will feel calm and relaxed from trazodone, which will help their overall well-being.&nbsp;<\/span><\/p>\n<h2 id=\"is-trazodone-safe-for-dogs\"><span style=\"font-weight: 400;\">Is trazodone safe for dogs?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Trazodone is prescribed very frequently because it is a safe and effective medication for dogs who have anxiety and need to calm down for medical procedures or stressful events. However, there are some drug interactions with trazodone. Medications that can interact with trazodone include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Certain antibiotics<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Some antidepressants, like monoamine oxidase inhibitors (MAOIs)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pain medications and anti-inflammatories<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heart medications&nbsp;<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Aspirin<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Antifungals, like ketoconazole<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">GI medications<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diuretics<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Be sure to tell your vet about all of the medications and supplements that your dog is taking before they prescribe trazodone. Trazodone can be used with some <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/ssris\"><span style=\"font-weight: 400;\">selective serotonin reuptake inhibitors<\/span><\/a><span style=\"font-weight: 400;\"> (SRRIs) like fluoxetine and benzodiazepines.&nbsp;<\/span><\/p>\n<h2 id=\"trazodone-for-dogs-side-effects\"><span style=\"font-weight: 400;\">Trazodone for dogs side effects<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Like any medication, trazodone can have side effects. Most are not serious, but some you should keep an eye out for and tell your veterinarian if your pet is experiencing them as they can be a sign of drug interaction or overdose.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Possible side effects of trazodone include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Anxiety<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Depression<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Aggression<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sedation or drowsiness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lethargy<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Vomiting<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diarrhea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ataxia (drunken gait)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Changes in appetite<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dilated pupils<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Fortunately, Dr. Bonk says, &ldquo;<\/span><span style=\"font-weight: 400;\">These side effects are very rare when the medication is given at the correct dose and typically go away within 24 hours.&rdquo;&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If your dog has a bad reaction to trazodone, there are alternatives. Some other sedatives your vet might prescribe include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/acepromazine-maleate\"><span style=\"font-weight: 400;\">Acepromazine<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/diazepam\"><span style=\"font-weight: 400;\">Diazepam<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/gabapentin\"><span style=\"font-weight: 400;\">Gabapentin<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/benadryl-allergy-extra-str\"><span style=\"font-weight: 400;\">Benadryl<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/alprazolam\"><span style=\"font-weight: 400;\">Alprazolam<\/span><\/a><\/li>\n<\/ul>\n<h3 id=\"what-happens-if-i-give-my-dog-too-much-trazodone\"><span style=\"font-weight: 400;\">What happens if I give my dog too much trazodone?&nbsp;<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Unfortunately, overdose is possible when it comes to sedatives like trazodone. Usually, too much trazodone leads to adverse effects like too much sedation, which will look like they are &ldquo;drunk&rdquo; from taking too much of the medication. That&rsquo;s why it&rsquo;s so important to always follow your vet&rsquo;s dosage recommendation, and not simply give your pet some of your prescription.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">There are some serious side effects from taking too much trazodone. &ldquo;When given in too high amounts or with other similar medications, trazodone can lead to serotonin syndrome that can cause vomiting, diarrhea, a high body temperature, seizures, drooling, incoordination, paralysis, coma, and even death,&rdquo; says Dr. Bonk. If you suspect your dog is having an overdose of trazodone or notice signs of serotonin syndrome, call your veterinarian or take your dog to an emergency pet clinic for further advice and treatment.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Since trazodone is a human medication, you can use SingleCare to save when you fill it at your regular pharmacy. Simply search for a coupon on singlecare.com, adjust for the dosage, location, and quantity, then show your pharmacist the coupon when you pick up your pet&rsquo;s Rx.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/singlecare-for-pet-prescriptions\/\"><b>Can I save on medication for my pets?<\/b><\/a><\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/es\/recursos\/trazodona-para-perros\"><span style=\"font-weight: 400;\">Lea este art&iacute;culo en espa&ntilde;ol aqu&iacute;.<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Just like their human best friends, dogs can feel anxious and even depressed sometimes. Also like humans, the medication trazodone is sometimes prescribed for dogs who aren&rsquo;t their usual happy selves. In humans, this medication treats depression and insomnia&mdash;thanks to its sedative effects. Here is what you should know about using this Rx in veterinary [&hellip;]<\/p>\n","protected":false},"author":135,"featured_media":57467,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[7956],"tags":[7969],"coauthors":[20599],"class_list":["post-57661","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pets","tag-dogs","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Trazodone for dogs: Uses, dosage, and side effects<\/title>\n<meta name=\"description\" content=\"Trazodone is an antidepressant and sedative that is used for dogs with anxiety. The extra-label uses include noise phobias, separation anxiety, or other calming needs.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.singlecare.com\/blog\/trazodone-for-dogs\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"How trazodone helps anxious dogs\" \/>\n<meta property=\"og:description\" content=\"This human Rx may help calm your furry friend\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.singlecare.com\/blog\/trazodone-for-dogs\/\" \/>\n<meta property=\"og:site_name\" content=\"The Checkup\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/singlecare\" \/>\n<meta property=\"article:published_time\" content=\"2023-03-27T13:30:52+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-10-25T14:48:20+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2023\/03\/Blog_032723_Trazodone_for_dogs.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"1080\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Laura Wheatman Hill\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:title\" content=\"How trazodone helps anxious dogs\" \/>\n<meta name=\"twitter:description\" content=\"This human Rx may help calm your furry friend\" \/>\n<meta name=\"twitter:creator\" content=\"@SingleCare\" \/>\n<meta name=\"twitter:site\" content=\"@SingleCare\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Laura Wheatman Hill\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/trazodone-for-dogs\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/trazodone-for-dogs\\\/\"},\"author\":{\"name\":\"Heidi Borst\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#\\\/schema\\\/person\\\/fda93df2f5d09af0d250b59dfb4b46f2\"},\"headline\":\"How trazodone can help anxious dogs\",\"datePublished\":\"2023-03-27T13:30:52+00:00\",\"dateModified\":\"2024-10-25T14:48:20+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/trazodone-for-dogs\\\/\"},\"wordCount\":1115,\"publisher\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/trazodone-for-dogs\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2023\\\/03\\\/Blog_032723_Trazodone_for_dogs.png\",\"keywords\":[\"Dogs\"],\"articleSection\":[\"Pets\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/trazodone-for-dogs\\\/\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/trazodone-for-dogs\\\/\",\"name\":\"Trazodone for dogs: Uses, dosage, and side effects\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/trazodone-for-dogs\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/trazodone-for-dogs\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2023\\\/03\\\/Blog_032723_Trazodone_for_dogs.png\",\"datePublished\":\"2023-03-27T13:30:52+00:00\",\"dateModified\":\"2024-10-25T14:48:20+00:00\",\"description\":\"Trazodone is an antidepressant and sedative that is used for dogs with anxiety. 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