{"id":58393,"date":"2023-05-18T09:30:21","date_gmt":"2023-05-18T13:30:21","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=58393"},"modified":"2026-04-03T08:43:27","modified_gmt":"2026-04-03T12:43:27","slug":"zyrtec-withdrawal","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/zyrtec-withdrawal\/","title":{"rendered":"What are the signs of Zyrtec withdrawal?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">If you have stubborn hay fever or seasonal allergies that aren\u2019t responsive to other over-the-counter antihistamines, you may find success with Zyrtec. Along with <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/xyzal-allergy-24hr\"><span style=\"font-weight: 400;\">Xyzal<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/levocetirizine-dihydrochloride\"><span style=\"font-weight: 400;\">levocetirizine<\/span><\/a><span style=\"font-weight: 400;\">), it is the <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15669879\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">most powerful<\/span><\/a><span style=\"font-weight: 400;\"> OTC antihistamine allergy medication available. The drug works effectively against allergy symptoms like itchy or watery eyes, sneezing, a runny nose, and an itchy nose or throat. However, stopping the drug after long-term use\u2014think months to years\u2014can cause unpleasant withdrawal symptoms.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">According to <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6613055\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">reports<\/span><\/a><span style=\"font-weight: 400;\"> submitted to the U.S. Food and Drug Administration (FDA), the most commonly experienced symptom from Zyrtec withdrawal is unbearable itching (pruritus) that happens within a couple of days of stopping the medication. Ranging in intensity from mild to severe, Zyrtec withdrawal itching can be uncomfortable, to say the least.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If you\u2019ve recently stopped taking this antihistamine, here\u2019s what you can do for Zyrtec withdrawal relief.\u00a0<\/span><\/p>\n\t\t<div id=\"coupon-cta\" class=\"coupon-cta master-template\">\n\t\t\t<p id=\"headline\">Save up to 80% on Zyrtec with SingleCare<\/p>\n\t\t\t<p id=\"subheadline\">Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t<div class=\"details-wrap\">\n\t\t\t\t<div class=\"details\">\n\t\t\t\t\tZyrtec 10 mg, 100 tablets (1 Bottle)\t\t\t\t<\/div>\n\t\t\t\t<div class=\"address\">\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"api-response\">\n\t\t\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/walgreens-logo.svg\" alt=\"Walgreens\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$2.89<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/zyrtec-allergy#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/zyrtec-allergy#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-kroger.svg\" alt=\"Kroger Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$9.34<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/zyrtec-allergy#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/zyrtec-allergy#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/zyrtec-allergy#blog-cta\" class=\"coupon-see-all-btn\">See Zyrtec prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n<h2 id=\"withdrawal-symptoms-of-zyrtec\"><span style=\"font-weight: 400;\">Withdrawal symptoms of Zyrtec<\/span><\/h2>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/zyrtec-allergy\"><span style=\"font-weight: 400;\">Zyrtec<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">and its generic<\/span> <a href=\"https:\/\/www.singlecare.com\/prescription\/cetirizine-hcl\"><span style=\"font-weight: 400;\">cetirizine<\/span><\/a><span style=\"font-weight: 400;\">) is an OTC antihistamine that <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK549776\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">relieves<\/span><\/a><span style=\"font-weight: 400;\"> sneezing, runny nose, and watery eyes associated with allergic rhinitis (seasonal or perennial allergies) caused by allergens like dust mites, mold, and pollen. <\/span><\/p>\n<p><span style=\"font-weight: 400;\">Common side effects that occur in people who take Zyrtec include sleepiness, fatigue, and dry mouth, says <\/span><a href=\"https:\/\/www.poison.org\/kelly-johnson-arbor-bio\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Kelly Johnson-Arbor, MD<\/span><\/a><span style=\"font-weight: 400;\">, a medical toxicologist and medical director at the <\/span><a href=\"http:\/\/www.poison.org\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">National Capital Poison Center<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><span style=\"font-weight: 400;\">\u00a0<\/span><span style=\"font-weight: 400;\">Although rare, there are reports of people experiencing withdrawal symptoms, including severe itching, after discontinuing use of Zyrtec, says Dr. Johnson-Arbor. These patients had taken Zyrtec continuously (daily) for several months to years, she says.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">According to <\/span><a href=\"https:\/\/pharmedicorx.com\/pages\/our-team\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Jill Barat, Pharm.D.<\/span><\/a><span style=\"font-weight: 400;\">, a compounding pharmacist at Pharmedico in Sarasota, Florida<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">symptoms of Zyrtec withdrawal include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Intense itching\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hives<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Vivid dreams<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Headaches<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">People who have experienced itching after discontinuation of Zyrtec often report that the itching is different than their symptoms of seasonal allergies, says Dr. Johnson-Arbor.<\/span><span style=\"font-weight: 400;\"> I<\/span><span style=\"font-weight: 400;\">tching from Zyrtec withdrawal can be severe, occurring all over the body and even as a moving itch that travels from place to place, making it difficult to relieve, says. Dr. Barat. Some people report that the itching is so bad, they end up damaging their skin from all the scratching, and\/or they are unable to sleep due to the discomfort, she adds.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/prescription\/zyrtec-allergy\/what-is\"><b>What is Zyrtec Allergy: Uses, Warnings &amp; Interactions<\/b><\/a><\/p>\n<h2 id=\"how-long-does-zyrtec-withdrawal-last\"><span style=\"font-weight: 400;\">How long does Zyrtec withdrawal last?\u00a0<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The exact timeline of Zyrtec withdrawal and which symptoms patients experience varies on a case-by-case basis, says Dr. Barat. \u201cSome people may not notice anything, while others may be driven to start back on the medication just to avoid these symptoms,\u201d she says, adding that the severity of withdrawal symptoms may be correlated with how long the person was using the drug.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">According to a 2019 Therapeutic Advances in Drug Safety <\/span><a href=\"https:\/\/journals.sagepub.com\/doi\/10.1177\/2042098619859996\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">report<\/span><\/a><span style=\"font-weight: 400;\">, the average start of itching after stopping Zyrtec is about two days. That said, anytime between half a day and five days after discontinuation of the drug has been reported, says Dr. Barat. In general, Zyrtec withdrawal occurs in three <\/span><a href=\"https:\/\/wellnessretreatrecovery.com\/antihistamine-withdrawal\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">phases<\/span><\/a><span style=\"font-weight: 400;\">:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Phase One:<\/b><span style=\"font-weight: 400;\"> Symptoms typically begin within three days of the last dose.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Phase Two:<\/b><span style=\"font-weight: 400;\"> Symptoms peak between days three to five.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Phase Three<\/b><span style=\"font-weight: 400;\">: Symptoms resolve in about seven days.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Withdrawal symptoms after stopping Zyrtec are rarely reported, so most people do not need to wean off of the drug, says Dr. Johnson-Arbor. But if you\u2019ve been taking daily Zyrtec for long periods of time (months to years), you might want to consider discontinuing the medication by slowly lowering your daily dose to avoid experiencing withdrawal symptoms.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In short, Zyrtec withdrawal itchiness can be uncomfortable, but it is not life-threatening, Dr. Johnson-Arbor says. In some cases, prescription medications may be needed to reduce the severity of Zyrtec withdrawal symptoms.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/taking-antihistamines-daily\/\"><b>Is it safe to take an antihistamine every day?<\/b><\/a><\/p>\n<h2 id=\"how-to-get-over-zyrtec-withdrawal\"><span style=\"font-weight: 400;\">How to get over Zyrtec withdrawal<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">For many people living with allergies, especially those who take Zyrtec for short periods of time, discontinuing the use of Zyrtec won\u2019t cause withdrawal, says Dr. Johnson-Arbor. The Zyrtec product label states that Zyrtec is not associated with abuse or dependence, so most people can stop the medication cold turkey without experiencing withdrawal.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">But if you\u2019ve been on Zyrtec long-term and you\u2019re worried about stopping cold turkey, slowly tapering your dose down over time may be a good way to avoid withdrawal, says Dr. Barat. She adds that a specific schedule for weaning from the medication, or a structured taper, is not currently written in the drug information for Zyrtec, so be sure to consult with a pharmacist, allergist, or similar healthcare professional for advice.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">For individuals who are experiencing Zyrtec withdrawal symptoms, taking a short course of\u00a0 corticosteroids may provide some relief, Dr. Barat says.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\t\t<div class=\"singlecare-dynamic-newsletter-wrapper sin-newsletter-wrapper\">\n\t\t\t<span class=\"heading\">Get our allergies newsletter<\/span>\n\t\t\t<form class=\"form-wrapper\" data-newsletter-form=\"1\" data-subsource=\"Allergies Newsletter\">\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<label for=\"dynamic-email\">Email<\/label>\n\t\t\t\t\t<input type=\"email\" id=\"dynamic-email\" class=\"email\" required>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<input class=\"submit-form-btn\" type=\"submit\" value=\"Click to sign up\">\n\t\t\t\t<\/div>\n\t\t\t<\/form>\n\t\t\t<p class=\"success-message\" aria-live=\"polite\"><\/p>\n\t\t<\/div>\n\t<\/span><\/p>\n<h2 id=\"alternatives-to-zyrtec\"><span style=\"font-weight: 400;\">Alternatives to Zyrtec<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">If you\u2019re worried about Zyrtec withdrawal, the antihistamines Allegra and Claritin, which are in the same class of drugs as Zyrtec, may be a better option for you, advises Dr. Barat.<\/span> <a href=\"https:\/\/www.singlecare.com\/prescription\/benadryl-allergy\/what-is\"><span style=\"font-weight: 400;\">Benadryl<\/span><\/a><span style=\"font-weight: 400;\"> (diphenhydramine), a first-generation antihistamine, is another option\u2014you shouldn&#8217;t experience itchy withdrawal issues, but it does cause more drowsiness than second-generation antihistamines such as <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/allegra-allergy\"><span style=\"font-weight: 400;\">Allegra<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/fexofenadine-hcl\"><span style=\"font-weight: 400;\">fexofenadine<\/span><\/a><span style=\"font-weight: 400;\">), <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/claritin\"><span style=\"font-weight: 400;\">Claritin<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/loratadine\"><span style=\"font-weight: 400;\">loratadine<\/span><\/a><span style=\"font-weight: 400;\">), and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/zyrtec-allergy\"><span style=\"font-weight: 400;\">Zyrtec<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/cetirizine-hcl\"><span style=\"font-weight: 400;\">cetirizine<\/span><\/a><span style=\"font-weight: 400;\">), says Dr. Barat. That\u2019s why it\u2019s best to take Benadryl at night. (First-generation antihistamines cross the <\/span><a href=\"https:\/\/my.clevelandclinic.org\/health\/drugs\/21223-antihistamines\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">blood-brain barrier<\/span><\/a><span style=\"font-weight: 400;\"> potentially causing drowsiness, while second-generation antihistamines typically do not). Benadryl can also have its own <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5874453\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">withdrawal syndrome<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If you experience unexpected signs or symptoms after using an antihistamine such as Zyrtec or Benadryl, contact Poison Control at poison.org or 1-800-222-1222. Both options are free of charge and are available 24 hours a day.<\/span><\/p>\n<h3 id=\"natural-alternatives\"><span style=\"font-weight: 400;\">Natural alternatives<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">If you\u2019re looking for a natural alternative to Zyrtec or other antihistamine medications, consider the use of saline nasal sprays. \u201cThese sprays can thin nasal mucous and help remove allergens from the nose and may help relieve the signs and symptoms of seasonal allergies,\u201d Dr. Johnson-Arbor says.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Dietary supplements may also be useful in alleviating allergy symptoms. For example, one older <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC64514\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">study<\/span><\/a><span style=\"font-weight: 400;\"> found that taking a supplement containing the plant butterbur four times a day was comparable to taking a daily dose of cetirizine among patients with seasonal allergies.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Dr. Barat says her pharmacy customers have shared success stories about the natural antihistamine supplement <\/span><a href=\"https:\/\/www.orthomolecularproducts.com\/product\/natural-d-hist\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">D-Hist<\/span><\/a><span style=\"font-weight: 400;\"> by Ortho Molecular. \u201cSome people buy many bottles at a time during allergy season to take every day as an antihistamine alternative,\u201d she says. The ingredients in D-Hist are quercetin, stinging nettle, bromelain (from pineapple), and N-acetyl-L-cysteine. <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6273625\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Quercetin<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3870104\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">bromelain<\/span><\/a><span style=\"font-weight: 400;\">, and <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5963652\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">stinging nettle<\/span><\/a><span style=\"font-weight: 400;\"> are all known for their anti-allergenic properties, and <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7487305\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">N-acetyl-L-cysteine<\/span><\/a><span style=\"font-weight: 400;\"> decreases the body\u2019s inflammatory response.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Not everyone who stops taking Zyrtec will experience withdrawal symptoms, says Dr. Barat. But if you do experience symptoms like relentless itching after ceasing the medication, reach out to your healthcare provider for advice.<\/span><\/p>\n<p><b>READ NEXT: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/seasonal-allergies-treatment\/\"><b>9 ways to treat seasonal allergies<\/b><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>If you have stubborn hay fever or seasonal allergies that aren\u2019t responsive to other over-the-counter antihistamines, you may find success with Zyrtec. Along with Xyzal (levocetirizine), it is the most powerful OTC antihistamine allergy medication available. The drug works effectively against allergy symptoms like itchy or watery eyes, sneezing, a runny nose, and an itchy [&hellip;]<\/p>\n","protected":false},"author":135,"featured_media":58216,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[554,12752],"coauthors":[20608],"class_list":["post-58393","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-allergies","tag-medication-side-effects","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Zyrtec withdrawal: Symptoms and relief<\/title>\n<meta name=\"description\" content=\"The symptoms of a Zyrtec withdrawal include intense itching, hives, and headaches. The itchiness associated with a Zyrtec withdrawal typically resolves within two days.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.singlecare.com\/blog\/zyrtec-withdrawal\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Did you know stopping Zyrtec can cause withdrawal?\" \/>\n<meta property=\"og:description\" content=\"Here\u2019s how to avoid symptoms when quitting\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.singlecare.com\/blog\/zyrtec-withdrawal\/\" \/>\n<meta property=\"og:site_name\" content=\"The Checkup\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/singlecare\" \/>\n<meta property=\"article:published_time\" content=\"2023-05-18T13:30:21+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-04-03T12:43:27+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2023\/05\/Blog_051823_Zyrtec_withdrawal.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"1080\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Heidi Borst\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:title\" content=\"Did you know stopping Zyrtec can cause withdrawal?\" \/>\n<meta name=\"twitter:description\" content=\"Here\u2019s how to avoid symptoms when quitting\" \/>\n<meta name=\"twitter:creator\" content=\"@SingleCare\" \/>\n<meta name=\"twitter:site\" content=\"@SingleCare\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Heidi Borst\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/zyrtec-withdrawal\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/zyrtec-withdrawal\\\/\"},\"author\":{\"name\":\"Heidi Borst\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#\\\/schema\\\/person\\\/fda93df2f5d09af0d250b59dfb4b46f2\"},\"headline\":\"What are the signs of Zyrtec withdrawal?\",\"datePublished\":\"2023-05-18T13:30:21+00:00\",\"dateModified\":\"2026-04-03T12:43:27+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/zyrtec-withdrawal\\\/\"},\"wordCount\":1174,\"publisher\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/zyrtec-withdrawal\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2023\\\/05\\\/Blog_051823_Zyrtec_withdrawal.png\",\"keywords\":[\"Allergies\",\"Medication side effects\"],\"articleSection\":[\"Drug Info\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/zyrtec-withdrawal\\\/\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/zyrtec-withdrawal\\\/\",\"name\":\"Zyrtec withdrawal: Symptoms and relief\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/zyrtec-withdrawal\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/zyrtec-withdrawal\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2023\\\/05\\\/Blog_051823_Zyrtec_withdrawal.png\",\"datePublished\":\"2023-05-18T13:30:21+00:00\",\"dateModified\":\"2026-04-03T12:43:27+00:00\",\"description\":\"The symptoms of a Zyrtec withdrawal include intense itching, hives, and headaches. 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