{"id":58409,"date":"2023-05-12T12:19:12","date_gmt":"2023-05-12T16:19:12","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=58409"},"modified":"2026-01-21T17:08:23","modified_gmt":"2026-01-21T22:08:23","slug":"best-time-of-day-to-take-zoloft-for-anxiety","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/best-time-of-day-to-take-zoloft-for-anxiety\/","title":{"rendered":"When is the best time of day to take Zoloft for anxiety?"},"content":{"rendered":"<p><iframe loading=\"lazy\" title=\"YouTube video player\" src=\"https:\/\/www.youtube.com\/embed\/jxMSrZsGgEI?rel=0\" width=\"560\" height=\"315\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/zoloft\"><span style=\"font-weight: 400;\">Zoloft<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/zoloft\/what-is\"><span style=\"font-weight: 400;\">sertraline<\/span><\/a><span style=\"font-weight: 400;\">) works as a selective serotonin reuptake inhibitor, or SSRI, to treat depression and other mental health conditions. It is usually prescribed to be <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/zoloft\/dosage\"><span style=\"font-weight: 400;\">taken by mouth once daily<\/span><\/a><span style=\"font-weight: 400;\">, with or without food. While it should be taken consistently, the best time of day to take Zoloft depends on how it affects you. If Zoloft makes you drowsy, you may want to take it in the evening, but if it makes you feel more awake, you may prefer to take it in the morning. Continue reading to learn more about Zoloft, including its side effects and the best time to take it.<\/span><\/p>\n<h2 id=\"what-is-zoloft\"><span style=\"font-weight: 400;\">What is Zoloft?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Zoloft is an <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/ssris\"><span style=\"font-weight: 400;\">SSRI antidepressant<\/span><\/a><span style=\"font-weight: 400;\"> that contains the active ingredient sertraline. It\u2019s believed to work by balancing serotonin, a brain chemical involved with managing mood and emotions. This SSRI medication is approved to treat the following conditions:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Major depressive disorder (<\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/depression-treatment-and-medications\"><span style=\"font-weight: 400;\">depression<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/ocd-treatment-and-medications\"><span style=\"font-weight: 400;\">Obsessive-compulsive disorder<\/span><\/a><span style=\"font-weight: 400;\"> (OCD)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/anxiety-treatment-and-medications\"><span style=\"font-weight: 400;\">Panic disorder<\/span><\/a><span style=\"font-weight: 400;\"> (PD)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/ptsd-treatment-and-medications\"><span style=\"font-weight: 400;\">Post-traumatic stress disorder<\/span><\/a><span style=\"font-weight: 400;\"> (PTSD)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Social anxiety disorder (SAD)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Premenstrual dysphoric disorder (PMDD)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Anxiety is a common condition, affecting around <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/news\/anxiety-statistics\/\"><span style=\"font-weight: 400;\">40 million<\/span><\/a><span style=\"font-weight: 400;\"> adults in the United States, with about 31% of adults experiencing an anxiety disorder at some point in their lives. Although it\u2019s commonly used for depression, Zoloft can treat <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/zoloft-for-anxiety\/\"><span style=\"font-weight: 400;\">anxiety<\/span><\/a><span style=\"font-weight: 400;\"> symptoms related to panic attacks and social situations. However, it can take up to several weeks for Zoloft to start improving mental health symptoms.\u00a0<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/zoloft-alternatives\/\"><b>Zoloft alternatives<\/b><\/a><b> | <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/zoloft-weight-gain\/\"><b>Does Zoloft cause weight gain?<\/b><\/a><\/p>\n<h2 id=\"when-is-the-best-time-of-day-to-take-zoloft-for-anxiety\"><span style=\"font-weight: 400;\">When is the best time of day to take Zoloft for anxiety?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=fe9e8b7d-61ea-409d-84aa-3ebd79a046b5\"><span style=\"font-weight: 400;\">prescribing information<\/span><\/a><span style=\"font-weight: 400;\"> for Zoloft does not recommend an optimal time to take your daily dose. So, the best way to take Zoloft would be to see how it makes you feel and decide on the best time of day that works for you.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In clinical trials, about 11% of patients taking Zoloft experienced drowsiness or sleepiness as a <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/zoloft-side-effects-first-week\/\"><span style=\"font-weight: 400;\">side effect<\/span><\/a><span style=\"font-weight: 400;\">. If Zoloft makes you feel tired, you may decide that taking it at bedtime works for you. However, about 20% of patients in clinical trials reported insomnia, or trouble sleeping, as a side effect of Zoloft. If Zoloft causes you to have trouble sleeping, you may choose to take it in the morning so that it does not affect your sleep.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Once you decide the best time of day to take Zoloft, it\u2019s best to be consistent and take it around the same time every day. For example, if you take it at 10:00 p.m., before bedtime, take it around that time every night.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">You can use a weekly pill box to keep your medications organized, or set a nightly reminder on your phone to remind you to take your medication. You can also ask your pharmacist for other ideas on <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/medication-management-for-seniors\/\"><span style=\"font-weight: 400;\">how to remember<\/span><\/a><span style=\"font-weight: 400;\"> to take your medication.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">It may take several weeks until you notice the full effect of <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2023\/019839s108,20990s062lbl.pdf\"><span style=\"font-weight: 400;\">taking Zoloft daily<\/span><\/a><span style=\"font-weight: 400;\">. Your doctor may start you on a low dose and slowly increase it if needed. If your symptoms do not improve, seek medical advice from your healthcare provider. Do not stop taking Zoloft unless your doctor tells you to do so.\u00a0<\/span><\/p>\n<h3 id=\"does-the-prescribed-dosage-affect-the-recommended-timing\"><span style=\"font-weight: 400;\">Does the prescribed dosage affect the recommended timing?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">For most people, the Zoloft dose doesn\u2019t change the best time to take it. Whether you\u2019re on a lower or higher dose, Zoloft is still taken once per day. If the dose is increased, most providers recommend keeping the same schedule at first. If new side effects develop, that\u2019s when it could make sense to switch the timing.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Certain medical conditions, such as liver disease, bipolar disorder, or a history of seizures, may affect how Zoloft is prescribed. A healthcare provider may consider these factors when prescribing the drug.<\/span><\/p>\n<h2 id=\"factors-influencing-zoloft-timing\"><span style=\"font-weight: 400;\">Factors influencing Zoloft timing<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">To truly pinpoint your ideal timing, we need to consider a few critical factors. Think of these as the variables in your personal Zoloft equation.<\/span><\/p>\n<h3 id=\"1-side-effects\"><span style=\"font-weight: 400;\">1. Side effects<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">This is one of the most important factors in Zoloft timing. Like most prescription medications, Zoloft can come with a range of side effects, especially when you <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/zoloft-side-effects-first-week\/\"><span style=\"font-weight: 400;\">first start taking it<\/span><\/a><span style=\"font-weight: 400;\"> or when your dose is adjusted. Some common side effects include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Nausea or digestive upset<\/b><span style=\"font-weight: 400;\">: For some, Zoloft can cause nausea, an upset stomach, diarrhea, constipation, and indigestion.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Drowsiness or fatigue<\/b><span style=\"font-weight: 400;\">: While less common than with some other SSRIs, some individuals find Zoloft makes them <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/does-zoloft-make-you-tired\/\"><span style=\"font-weight: 400;\">feel sleepy<\/span><\/a><span style=\"font-weight: 400;\"> or fatigued.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Insomnia or agitation<\/b><span style=\"font-weight: 400;\">: Conversely, others experience an activating effect, leading to <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/medications-that-cause-insomnia\/\"><span style=\"font-weight: 400;\">difficulty sleeping<\/span><\/a><span style=\"font-weight: 400;\"> or feeling restless.<\/span><\/li>\n<\/ul>\n<p><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC9978765\/\"><span style=\"font-weight: 400;\">Higher doses<\/span><\/a><span style=\"font-weight: 400;\"> of an antidepressant medication could cause you to feel more side effects, such as dry mouth, dizziness, fatigue, or agitation. Higher serotonin levels are also linked to serious side effects, such as serotonin syndrome and suicidal thoughts, in severe cases. Other potential side effects include sexual dysfunction, weight loss, and joint pain.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The timing becomes key here: if Zoloft makes you drowsy, taking it in the morning might hinder your daytime activities. If it keeps you awake, a morning dose would be preferable to an evening one. If it upsets your stomach, taking it with a meal, regardless of time, can be very helpful.<\/span><\/p>\n<h3 id=\"2-personal-schedule\"><span style=\"font-weight: 400;\">2. Personal schedule\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Consistency is important for any long-term drug like Zoloft. It needs to be taken regularly, ideally at roughly the same time each day. While it doesn\u2019t have to be taken at the exact same hour and minute every day, having a regular schedule can help keep drug levels steady.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Consider your daily routine:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Are you a morning person with a predictable breakfast routine?<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Do you often forget things in the morning rush?<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Is your evening more stable, perhaps with dinner at a consistent hour?<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">The &#8220;best&#8221; time is one you can reliably stick to, day in and day out, without fail. Forgetting doses can lead to changing medication levels, potentially decreasing efficacy or even triggering withdrawal symptoms if doses are <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/missed-dose-of-zoloft\/\"><span style=\"font-weight: 400;\">constantly missed<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h3 id=\"3-individual-response-to-medication\"><span style=\"font-weight: 400;\">3. Individual response to medication<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">You are unique, and so is your body&#8217;s response to medication. Two people taking the exact same dose of Zoloft might experience entirely different side effects or treatment timelines. This variability means that what works for your friend or a family member might not be what works best for you. It&#8217;s often about adapting to what works.<\/span><\/p>\n<h2 id=\"morning-dosing-pros-and-cons\"><span style=\"font-weight: 400;\">Morning dosing: Pros and cons<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Taking Zoloft in the morning can work well for many people who don\u2019t experience drowsiness. This timing can also be ideal for those with specific morning routines.<\/span><\/p>\n<h3 id=\"pros\"><span style=\"font-weight: 400;\">Pros\u00a0<\/span><\/h3>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Helps avoid daytime sleepiness if Zoloft makes you drowsy\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Takes advantage of its energizing effects for people who feel more alert on it\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Easy to pair with other morning habits, which can improve consistency\u00a0<\/span><\/li>\n<\/ul>\n<h3 id=\"cons\"><span style=\"font-weight: 400;\">Cons\u00a0<\/span><\/h3>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea or stomach upset may interfere with your day, especially early on\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Some people experience <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/brain-fog-causes\"><span style=\"font-weight: 400;\">brain fog<\/span><\/a><span style=\"font-weight: 400;\"> or problems with focus during peak daytime hours\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Busy mornings can increase the risk of forgetting a dose<\/span><\/li>\n<\/ul>\n<h2 id=\"evening-dosing-pros-and-cons\"><span style=\"font-weight: 400;\">Evening dosing: Pros and cons<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Some people prefer to take Zoloft at night based on the side effects. Those with a more concrete evening routine may also find it more convenient to take Zoloft at that time.\u00a0<\/span><\/p>\n<h3 id=\"heading-12\"><span style=\"font-weight: 400;\">Pros\u00a0<\/span><\/h3>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">May reduce the severity of side effects during the workday\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Can help with sleep if Zoloft causes drowsiness\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fits easily into a nightly routine, such as after dinner or before bed<\/span><\/li>\n<\/ul>\n<h3 id=\"heading-13\"><span style=\"font-weight: 400;\">Cons\u00a0<\/span><\/h3>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">May worsen insomnia or restlessness in people who find that Zoloft stimulates their brain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea at night can disrupt sleep\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Greater chance of <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/sertraline-interactions\/\"><span style=\"font-weight: 400;\">drug interactions<\/span><\/a><span style=\"font-weight: 400;\"> with evening medications, supplements, or alcohol<\/span><\/li>\n<\/ul>\n<h2 id=\"tips-for-optimizing-your-zoloft-regimen\"><span style=\"font-weight: 400;\">Tips for optimizing your Zoloft regimen<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Beyond morning or evening timing, there may be other strategies to help you get the most benefit from Zoloft.<\/span><\/p>\n<h3 id=\"consistency-is-key\"><span style=\"font-weight: 400;\">Consistency is key<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">This cannot be overstated. Pick a time and stick to it as closely as possible every single day. Erratic dosing could make the drug less effective at managing symptoms. If you miss a dose of Zoloft, take it as soon as you remember unless it\u2019s close to your next dose. If it\u2019s almost time for your next dose, skip the missed dose and continue your regular schedule. Don\u2019t double-dose to make up for a missed dose.<\/span><\/p>\n<h3 id=\"taking-zoloft-with-food\"><span style=\"font-weight: 400;\">Taking Zoloft with food<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">For many, taking Zoloft with food helps reduce digestive <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/sertraline-side-effects\/\"><span style=\"font-weight: 400;\">side effects<\/span><\/a><span style=\"font-weight: 400;\"> such as nausea and an upset stomach. It doesn&#8217;t need to be a huge meal, but a decent snack or a main meal can provide a buffer. This is a common and highly effective strategy, whether you take it in the morning or the evening.<\/span><\/p>\n<h3 id=\"setting-reminders\"><span style=\"font-weight: 400;\">Setting reminders<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">People who are busy professionals can often find it hard to remember to take their medication. Setting a daily alarm on your phone, using a medication reminder app, or even linking it to a recurring calendar event can be useful. You could also place your medication in a highly visible spot that&#8217;s part of your routine, like next to your toothbrush or <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/zoloft-and-coffee\/\"><span style=\"font-weight: 400;\">coffee maker<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h3 id=\"keeping-a-medication-journal\"><span style=\"font-weight: 400;\">Keeping a medication journal<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">This can be an effective tool, especially in the early weeks. Jot down the time you took your Zoloft, any side effects you experienced (and their severity or duration), your general mood, and overall sleep quality. A <\/span><a href=\"https:\/\/www.fda.gov\/consumers\/consumer-updates\/create-and-keep-medication-list-your-health\"><span style=\"font-weight: 400;\">medication journal<\/span><\/a><span style=\"font-weight: 400;\"> can be helpful for you and your doctor, allowing you to see patterns and make the right changes to your timing or dosage.\u00a0<\/span><\/p>\n<h2 id=\"when-to-re-evaluate-your-zoloft-timing\"><span style=\"font-weight: 400;\">When to re-evaluate your Zoloft timing<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Your Zoloft regimen isn&#8217;t set in stone. Your body changes, your life changes, and sometimes, what once worked perfectly needs a small adjustment.<\/span><\/p>\n<h3 id=\"persistent-side-effects\"><span style=\"font-weight: 400;\">Persistent side effects<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">If you&#8217;ve been on Zoloft for several weeks, and particularly if you&#8217;ve increased your dose, persistent or worsening side effects are a clear sign that a change is needed. Persistent side effects can include ongoing nausea and <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK554406\/\"><span style=\"font-weight: 400;\">changes in sleep<\/span><\/a><span style=\"font-weight: 400;\"> that disrupt daily functioning. These aren&#8217;t just minor inconveniences; they can significantly affect your quality of life and your adherence to the treatment plan.<\/span><\/p>\n<h3 id=\"changes-in-lifestyle-or-routine\"><span style=\"font-weight: 400;\">Changes in lifestyle or routine<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Life happens. A new job with a different schedule, becoming a parent, a significant change in sleep patterns, or even relocating to a different time zone can all affect how your medication timing affects you. If your lifestyle changes, your medication schedule might need to change with it.<\/span><\/p>\n<h3 id=\"lack-of-efficacy\"><span style=\"font-weight: 400;\">Lack of efficacy<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Zoloft takes time to work, but if you&#8217;ve reached a stable dose and have been consistently taking it for several weeks without improvement in symptoms, timing might be a factor. However, it&#8217;s more likely your doctor will consider a dose change or <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/switching-antidepressants\/\"><span style=\"font-weight: 400;\">other treatment options<\/span><\/a><span style=\"font-weight: 400;\">. Still, taking it at an optimal dose and time can affect how effective it is.\u00a0<\/span><\/p>\n<h2 id=\"how-to-save-on-your-zoloft-prescription\"><span style=\"font-weight: 400;\">How to save on your Zoloft prescription<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Medications can be costly, and many people have trouble affording their prescription drugs. Fortunately, there are several options available to help you save on your Zoloft prescription.\u00a0<\/span><\/p>\n<ol>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Choose the generic<\/b><span style=\"font-weight: 400;\">. Generic Zoloft (sertraline) could save you a considerable amount more than the brand-name version. Generics are required by the U.S. Food and Drug Administration (FDA) to be the <\/span><a href=\"https:\/\/www.fda.gov\/drugs\/generic-drugs\/generic-drug-facts\"><span style=\"font-weight: 400;\">same<\/span><\/a><span style=\"font-weight: 400;\"> as their brand-name counterparts, so they are just as effective at a lower cost.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Compare prices<\/b><span style=\"font-weight: 400;\">. Most insurance companies and Medicare prescription plans cover generic sertraline. However, you may want to ask your pharmacist to compare the price with your insurance to the cost with a free <\/span><a href=\"https:\/\/www.singlecare.com\/prescription-discount-card\"><span style=\"font-weight: 400;\">SingleCare card<\/span><\/a><span style=\"font-weight: 400;\">. Anyone with a valid prescription can use SingleCare at participating pharmacies across the U.S. and Puerto Rico. What\u2019s more, you can use SingleCare on refills, too. Check the SingleCare website or mobile app to start saving today.<\/span><\/li>\n<\/ol>\n<p><span style=\"font-weight: 400;\">\t\t<div id=\"coupon-cta\" class=\"coupon-cta master-template\">\n\t\t\t<p id=\"headline\">Save up to 80% on Zoloft with SingleCare<\/p>\n\t\t\t<p id=\"subheadline\">Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t<div class=\"details-wrap\">\n\t\t\t\t<div class=\"details\">\n\t\t\t\t\tZoloft 50 mg (30 Tablets)\t\t\t\t<\/div>\n\t\t\t\t<div class=\"address\">\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"api-response\">\n\t\t\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-kroger.svg\" alt=\"Kroger Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$8.72<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/zoloft#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/zoloft#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-harristeeter.svg\" alt=\"Harris Teeter Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$8.72<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/zoloft#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/zoloft#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/zoloft#blog-cta\" class=\"coupon-see-all-btn\">See Zoloft prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Zoloft (sertraline) works as a selective serotonin reuptake inhibitor, or SSRI, to treat depression and other mental health conditions. It is usually prescribed to be taken by mouth once daily, with or without food. While it should be taken consistently, the best time of day to take Zoloft depends on how it affects you. If [&hellip;]<\/p>\n","protected":false},"author":133,"featured_media":58412,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[8029],"tags":[9777,450,4350],"coauthors":[10668],"class_list":["post-58409","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health-education","tag-anxiety","tag-mental-health","tag-prescription-savings","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>When is the best time of day to take Zoloft for anxiety?<\/title>\n<meta name=\"description\" content=\"The best time of day to take Zoloft for anxiety can vary, but it should be taken at the same time every day. 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