{"id":58948,"date":"2023-06-16T12:02:44","date_gmt":"2023-06-16T16:02:44","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=58948"},"modified":"2024-10-25T10:39:46","modified_gmt":"2024-10-25T14:39:46","slug":"lorazepam-for-sleep","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/lorazepam-for-sleep\/","title":{"rendered":"Lorazepam for sleep: Can lorazepam help with sleep?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">For many, falling asleep at night isn&#8217;t always as simple as lying down and closing one&rsquo;s eyes. Worries from the day may race through the mind, or getting comfortable may be impossible. Although it is normal to have trouble falling asleep and maintaining sleep occasionally, chronic insomnia can take its toll physically and mentally on one&rsquo;s daily life. When relaxation techniques don&rsquo;t work, many people with sleep problems <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/sleep-aids-guide\"><span style=\"font-weight: 400;\">look for medications<\/span><\/a><span style=\"font-weight: 400;\"> to aid in the process.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">While taking over-the-counter (OTC) sleep aids and supplements may help some, many times, people seek medical professional help and may be prescribed sleeping pills. Benzodiazepines, which include <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/valium\"><span style=\"font-weight: 400;\">Valium<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/diazepam\/what-is\"><span style=\"font-weight: 400;\">diazepam<\/span><\/a><span style=\"font-weight: 400;\">) and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/xanax\"><span style=\"font-weight: 400;\">Xanax<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/alprazolam\/what-is\"><span style=\"font-weight: 400;\">alprazolam<\/span><\/a><span style=\"font-weight: 400;\">), are one of the most widely prescribed drug classes for the short-term treatment of insomnia. While several benzodiazepines are approved by the U.S. Food and Drug Administration (FDA) for treating insomnia, lorazepam, a benzodiazepine also known by the brand name Ativan and FDA-approved to treat anxiety, is often prescribed <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/off-label-prescription-drugs\/\"><span style=\"font-weight: 400;\">off-label<\/span><\/a><span style=\"font-weight: 400;\"> as a sleep aid. Continue reading to learn how lorazepam works, who can take it, and possible side effects.&nbsp;<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/how-to-sleep-better\"><b>21 ways to sleep better tonight<\/b><\/a><\/p>\n<h2 id=\"lorazepam-for-sleep\"><span style=\"font-weight: 400;\">Lorazepam for sleep<\/span><\/h2>\n<p><a href=\"https:\/\/www.singlecare.com\/drug-classes\/benzodiazepines\"><span style=\"font-weight: 400;\">Benzodiazepines<\/span><\/a><span style=\"font-weight: 400;\"> are a class of medications that work by making the central nervous system (CNS) less active. This decrease in nervous system activity makes these medications helpful for various medical conditions, such as daytime anxiety disorders and seizures. <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4730295\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Clinical studies<\/span><\/a><span style=\"font-weight: 400;\"> have shown them to be safe and effective for the treatment of insomnia since their first approval in the 1970s. Lorazepam, approved by the FDA in 1977 under the brand name Ativan, is indicated for the short-term relief of anxiety symptoms. It is often prescribed off-label for the short-term treatment of insomnia.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Many prescription drugs are prescribed off-label to treat conditions other than those for which they were approved. Since lorazepam has calming effects similar to the benzodiazepines approved to treat insomnia, it is often considered by prescribing healthcare professionals to be an effective option. A <\/span><a href=\"https:\/\/karger.com\/ipd\/article-abstract\/15\/2\/129\/178985\/Efficacy-and-Side-Effects-of-Lorazepam-Oxazepam\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">clinical trial<\/span><\/a><span style=\"font-weight: 400;\"> has also shown that lorazepam is as effective as other benzodiazepines in the short-term treatment of insomnia in trial subjects.<\/span><\/p>\n<h2 id=\"who-can-take-lorazepam-as-a-sleep-aid\"><span style=\"font-weight: 400;\">Who can take Lorazepam as a sleep aid?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Lorazepam is considered safe and effective for use in those <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2016\/017794s044lbl.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">12 years of age and older<\/span><\/a><span style=\"font-weight: 400;\">, although off-label use as a sleep aid is usually reserved for adults. Those aged 65 and over may respond to lorazepam with an increase in the incidence of sedation and unsteadiness, therefore, dosing in older patients should start at lower doses and be increased cautiously.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Taking lorazepam may not be suitable for some people with any of the following medical histories or <\/span><span style=\"font-weight: 400;\">:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Known hypersensitivity to the active drug or any ingredient<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Liver or kidney disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lung disease or breathing problems (e.g., sleep apnea or COPD)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Have depression, mood problems, or suicidal thoughts or behavior<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Have a history of drug or alcohol abuse or substance use disorder<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Are trying to get pregnant, are already pregnant, or are breastfeeding<\/span><\/li>\n<li>Have glaucoma (a condition of increased pressure within the eye)<\/li>\n<\/ul>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/ativan-and-alcohol\"><b>Is it safe to mix Ativan and alcohol?<\/b><\/a><\/p>\n<h3 id=\"how-long-does-lorazepam-take-to-work\"><span style=\"font-weight: 400;\">How long does lorazepam take to work<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Doses of lorazepam oral tablets are well absorbed after swallowing and will typically start to work in about 30 minutes, with peak effects lasting two to three hours. This means that lorazepam can be taken just before bedtime for most people.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Lorazepam is a <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/controlled-substances-act\/\"><span style=\"font-weight: 400;\">federally controlled substance<\/span><\/a><span style=\"font-weight: 400;\"> (Schedule IV) because it can be abused or lead to physical dependence. Because of this, it is recommended to use the lowest effective dose for the shortest period of time. It is usually prescribed for no more than four weeks at a time and is not recommended for use beyond four months. Lorazepam may be taken daily or as needed, depending on your doctor&#8217;s or other healthcare provider&rsquo;s instructions.&nbsp;<\/span><\/p>\n<h2 id=\"lorazepam-dosage-for-sleep\"><span style=\"font-weight: 400;\">Lorazepam dosage for sleep<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">For short-term treatment of insomnia, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/ativan\/dosage\"><span style=\"font-weight: 400;\">a single dose of 2 to 4 mg<\/span><\/a><span style=\"font-weight: 400;\"> is taken at bedtime.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">For a person over 65, <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK532890\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">the initial dose<\/span><\/a><span style=\"font-weight: 400;\"> should be reduced to 0.5 to 1 mg at bedtime to achieve the desired effect. Changes to this low dose may be made as needed and tolerated.<\/span><\/p>\n<h2 id=\"lorazepam-alternatives\"><span style=\"font-weight: 400;\">Lorazepam alternatives<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Many non-drug methods can help those who have trouble falling asleep that may be tried at home, including:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Physical activity early in the day can improve the quality of sleep, however, avoid exercising within two hours of bedtime<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stick to a regular sleep schedule&nbsp;<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Eat a healthy diet, but avoid big meals within a couple of hours of bedtime<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Avoid watching TV or using a phone or tablet right before going to bed<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">The chart below includes some common brand-name medications and OTC products that may be used for insomnia.<\/span><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h2 id=\"alternatives-to-lorazepam-for-sleep\"><span class=\"title\">Alternatives to lorazepam for sleep<\/span><\/h2>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><span style=\"font-weight: 400;\">Medication<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Drug class<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Standard dosage<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Savings options (coupon)<\/span><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/ambien\/what-is\"><span style=\"font-weight: 400;\">Ambien<\/span><\/a><\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/zolpidem-tartrate\/what-is\"><span style=\"font-weight: 400;\">(zolpidem)<\/span><\/a><\/p>\n<p><i><span style=\"font-weight: 400;\">Rx<\/span><\/i><\/td>\n<td><span style=\"font-weight: 400;\">Sedative-hypnotic<\/span><\/td>\n<td><span style=\"font-weight: 400;\">5 mg for women, 5-10 mg for men before bedtime<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/ambien\"><span style=\"font-weight: 400;\">Ambien coupon<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/lunesta\/what-is\"><span style=\"font-weight: 400;\">Lunesta<\/span><\/a><\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/eszopiclone\/what-is\"><span style=\"font-weight: 400;\">(eszopiclone)<\/span><\/a><\/p>\n<p><i><span style=\"font-weight: 400;\">Rx<\/span><\/i><\/td>\n<td><span style=\"font-weight: 400;\">Sedative-hypnotic<\/span><\/td>\n<td><span style=\"font-weight: 400;\">1 to 3 mg at bedtime<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/lunesta\"><span style=\"font-weight: 400;\">Lunesta coupon<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/restoril\/what-is\"><span style=\"font-weight: 400;\">Restoril<\/span><\/a><\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/temazepam\/what-is\"><span style=\"font-weight: 400;\">(temazepam)<\/span><\/a><\/p>\n<p><i><span style=\"font-weight: 400;\">Rx<\/span><\/i><\/td>\n<td><span style=\"font-weight: 400;\">Benzodiazepine<\/span><\/td>\n<td><span style=\"font-weight: 400;\">15 mg at bedtime<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/restoril\"><span style=\"font-weight: 400;\">Restoril coupon<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/doxepin-hcl\/what-is\"><span style=\"font-weight: 400;\">Silenor<\/span><\/a><\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/doxepin-hcl\/what-is\"><span style=\"font-weight: 400;\">(doxepin)<\/span><\/a><span style=\"font-weight: 400;\">&nbsp;<\/span><\/p>\n<p><i><span style=\"font-weight: 400;\">Rx<\/span><\/i><\/td>\n<td><span style=\"font-weight: 400;\">Tricyclic antidepressant (TCA)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">6 mg for adults, 3 mg for older adults before bedtime<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/doxepin-hcl\"><span style=\"font-weight: 400;\">Silenor coupon<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td>\n<p><i><span style=\"font-weight: 400;\">OTC<\/span><\/i><\/td>\n<td><span style=\"font-weight: 400;\">Natural hormone<\/span><\/td>\n<td><span style=\"font-weight: 400;\">1-2 mg daily for adults, 0.5 mg daily for children 3 and older<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/melatonin\"><span style=\"font-weight: 400;\">Melatonin coupon<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/unisom-sleeptabs\/what-is\"><span style=\"font-weight: 400;\">Unisom<\/span><\/a><\/p>\n<p><i><span style=\"font-weight: 400;\">OTC<\/span><\/i><\/td>\n<td><span style=\"font-weight: 400;\">Antihistamine<\/span><\/td>\n<td><span style=\"font-weight: 400;\">25 mg at bedtime<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/unisom-sleeptabs\"><span style=\"font-weight: 400;\">Unisom coupon<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/ativan-alternatives\/\"><b>Ativan alternatives<\/b><\/a><b>  <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/otc-sleep-aids\"><b>Is it safe to take OTC sleep aids every night?<\/b><\/a><\/p>\n<h2 id=\"lorazepam-side-effects-and-warnings\"><span style=\"font-weight: 400;\">Lorazepam side effects and warnings<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Like any medicine, lorazepam may cause <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> in some people. Some of the more common side effects when taking lorazepam for insomnia include the following symptoms:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lightheadedness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Unsteadiness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Decreased ability to concentrate<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Muscle weakness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dry mouth<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Rare but more <\/span><span style=\"font-weight: 400;\">serious side effects<\/span><span style=\"font-weight: 400;\"> that may require medical help include the following symptoms:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Shuffling walk<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tremors or inability to sit still<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fever<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Breathing problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Difficulty swallowing<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Skin rash or hives<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Yellowing of skin or eyes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Irregular heartbeat&nbsp;<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Memory loss or memory problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Disorientation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sleep apnea or worsening of sleep apnea<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Taking lorazepam for a long time, particularly at high doses, may result in long-term effects, usually seen as exaggerated versions of the side effects listed above.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Withdrawal from benzodiazepines, including lorazepam, can be potentially dangerous. The rate of drug withdrawal, the strength of the dose taken, and the longer use time will contribute to how severe the withdrawal symptoms might be. The most common withdrawal symptoms include a significant worsening of sleep, headaches, sweating, tremors, increased blood pressure, GI effects (e.g., nausea, cramps, vomiting), tension, irritability, anxiety, mental confusion, and even seizures in rare cases. Lorazepam should be gradually stopped under medical supervision.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Lorazepam has a <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/black-box-warning\/\"><span style=\"font-weight: 400;\">black box warning<\/span><\/a><span style=\"font-weight: 400;\">, also known as a boxed warning, regarding the combined use of lorazepam and opioid medications, a class of drugs used to reduce pain. Combining the two medications can worsen adverse reactions caused by lorazepam alone and may result in medical emergencies such as profound sedation, respiratory depression, coma, and death. Following a physician&rsquo;s or other healthcare professional&rsquo;s medical advice, is important in order to avoid risks when combining lorazepam with another sedating drug.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>For many, falling asleep at night isn&#8217;t always as simple as lying down and closing one&rsquo;s eyes. Worries from the day may race through the mind, or getting comfortable may be impossible. Although it is normal to have trouble falling asleep and maintaining sleep occasionally, chronic insomnia can take its toll physically and mentally on [&hellip;]<\/p>\n","protected":false},"author":133,"featured_media":58952,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[],"coauthors":[20733],"class_list":["post-58948","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Lorazepam for sleep: Can lorazepam help with sleep? | SingleCare<\/title>\n<meta name=\"description\" content=\"Lorazepam treats anxiety but may be used off-label as a sleep aid if other insomnia treatments don&#039;t work. Here\u2019s what you should know about using Lorazepam for sleep.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.singlecare.com\/blog\/lorazepam-for-sleep\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Lorazepam for sleep: Can lorazepam help with sleep?\" \/>\n<meta property=\"og:description\" content=\"Lorazepam treats anxiety but may be used off-label as a sleep aid if other insomnia treatments don&#039;t work. 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