{"id":61239,"date":"2023-11-08T09:30:33","date_gmt":"2023-11-08T14:30:33","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=61239"},"modified":"2025-02-19T15:28:54","modified_gmt":"2025-02-19T20:28:54","slug":"semaglutide-storage","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/semaglutide-storage\/","title":{"rendered":"Does Ozempic need to be refrigerated?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">You\u2019ve likely heard about <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/ozempic-0-25-or-0-5-mg-dose\/what-is\"><span style=\"font-weight: 400;\">Ozempic<\/span><\/a><span style=\"font-weight: 400;\"> (semaglutide), a <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/glp-1-agonists\"><span style=\"font-weight: 400;\">glucagon-like peptide-1 (GLP-1) receptor agonist<\/span><\/a><span style=\"font-weight: 400;\"> approved by the Food &amp; Drug Administration (FDA) to manage blood sugar levels for people with <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/type-2-diabetes-treatment-and-medications\"><span style=\"font-weight: 400;\">Type 2 diabetes<\/span><\/a><span style=\"font-weight: 400;\">. It gained approval in 2017 but has surged in popularity recently due to the medication\u2019s ability to help with weight loss. <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/ozempic\"><span style=\"font-weight: 400;\">Ozempic<\/span><\/a><span style=\"font-weight: 400;\"> can be prescribed <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/off-label-prescription-drugs\/\"><span style=\"font-weight: 400;\">off-label<\/span><\/a><span style=\"font-weight: 400;\"> (a use that is not FDA-approved) for weight loss, or your healthcare provider may prescribe <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/wegovy\"><span style=\"font-weight: 400;\">Wegovy<\/span><\/a><span style=\"font-weight: 400;\">, an injectable medication that is made by the same manufacturer with the same active ingredient and that <\/span><i><span style=\"font-weight: 400;\">is<\/span><\/i><span style=\"font-weight: 400;\"> approved for weight loss.<\/span><\/p>\n<p><span data-sheets-root=\"1\"><\/span><\/p>\n<p><span style=\"font-weight: 400;\">Ozempic and Wegovy are both prefilled pens given as a weekly injection. To make sure the medication remains safe to use and lasts until its expiration date, you need to store it properly when you\u2019re at home or taking a trip. For Ozempic, that means keeping it refrigerated\u2014most of the time.<\/span><\/p>\n<h2 id=\"does-ozempic-need-to-be-refrigerated\"><span style=\"font-weight: 400;\">Does Ozempic need to be refrigerated?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Whether Ozempic needs to be refrigerated depends on whether it has been used yet.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If your Ozempic pen is new, the <\/span><a href=\"https:\/\/www.ozempic.com\/how-to-take\/ozempic-pen.html\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">manufacturer<\/span><\/a><span style=\"font-weight: 400;\"> recommends that it should be refrigerated between 36 and 46 degrees Fahrenheit. Ozempic pens are intended for multiple uses, so once it is opened, you can continue to keep them for up to 56 days in the fridge or at room temperature. If you decide not to keep your used Ozempic pen refrigerated, make sure it\u2019s not exposed to temperatures below 59 F or above 86 F.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\t\t<div class=\"singlecare-dynamic-newsletter-wrapper sin-newsletter-wrapper\">\n\t\t\t<span class=\"heading\">Get our weight management newsletter<\/span>\n\t\t\t<form class=\"form-wrapper\" data-newsletter-form=\"1\" data-subsource=\"Weight Management Newsletter\">\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<label for=\"dynamic-email\">Email<\/label>\n\t\t\t\t\t<input type=\"email\" id=\"dynamic-email\" class=\"email\" required>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<input class=\"submit-form-btn\" type=\"submit\" value=\"Click to sign up\">\n\t\t\t\t<\/div>\n\t\t\t<\/form>\n\t\t\t<p class=\"success-message\" aria-live=\"polite\"><\/p>\n\t\t<\/div>\n\t<\/span><\/p>\n<h2 id=\"does-wegovy-need-to-be-refrigerated\"><span style=\"font-weight: 400;\">Does Wegovy need to be refrigerated?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The Wegovy <\/span><a href=\"https:\/\/www.novomedlink.com\/obesity\/products\/treatments\/wegovy\/resources\/frequently-asked-questions.html\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">manufacturer<\/span><\/a><span style=\"font-weight: 400;\"> also recommends that Wegovy pens should be refrigerated between 36 F and 46 F. However, unopened Wegovy pens can be stored outside of the refrigerator in temperatures between 46 F and 86 F if needed, in the original carton, for up to 28 days. Unlike Ozempic, Wegovy is available as a single-use pen, so it should be safely discarded after use.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">When storing Ozempic or Wegovy outside of the refrigerator, it \u201cshould be kept out of direct sunlight and away from excessive heat,\u201d says <\/span><a href=\"https:\/\/app.pharmacy.vcu.edu\/emsisson\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Evan Sisson<\/span><\/a><span style=\"font-weight: 400;\">, Pharm.D., vice chair of Practice and Service in the VCU School of Pharmacy&#8217;s Department of Pharmacotherapy and Outcomes Science.\u00a0<\/span><\/p>\n<h2 id=\"how-long-can-ozempic-and-wegovy-be-left-unrefrigerated\"><span style=\"font-weight: 400;\">How long can Ozempic and Wegovy be left unrefrigerated?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Unopened Ozempic should always be refrigerated. After you have used your Ozempic pen, the medication can be kept either in the refrigerator or at room temperature for up to 56 days.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Unopened Wegovy pens can be stored in the refrigerator. Or, unlike Ozempic, unopened Wegovy pens <\/span><i><span style=\"font-weight: 400;\">can<\/span><\/i><span style=\"font-weight: 400;\"> be stored unrefrigerated with the pen cap still on for up to 28 days at temperatures between 46 F and 86 F. It should be kept in the original carton to protect it from light.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If you are home, you likely will not have any issues with the storage recommendations. However, if you\u2019re traveling, you may need to take some extra steps: You can purchase an insulin pouch with an ice pack to transport it.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">As with any medication, you should put Ozempic or Wegovy in your carry-on luggage so it\u2019s guaranteed to arrive with you at your destination. <\/span><a href=\"https:\/\/www.tsa.gov\/travel\/travel-tips\/can-you-pack-your-meds-pill-case-and-more-questions-answered\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Although the Transportation Security Administration (TSA) does allow<\/span><\/a><span style=\"font-weight: 400;\"> you to travel with liquid medications, it never hurts to get a letter from your prescribing provider explaining your need for the medication. This should make your screening through airport security go smoother.<\/span><\/p>\n<p><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/ozempic\"><span style=\"font-weight: 400;\">Ozempic coupons<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/wegovy\"><span style=\"font-weight: 400;\">Wegovy coupons<\/span><\/a><\/p>\n<h2 id=\"why-does-ozempic-need-to-be-refrigerated\"><span style=\"font-weight: 400;\">Why does Ozempic need to be refrigerated?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Storing Ozempic properly preserves its quality, safety, and effectiveness. \u201cProteins, like Ozempic, may break down or lose potency if exposed to heat,\u201d Dr. Sisson says. \u201cOzempic that has not been stored properly is unlikely to be harmful but will be less effective than expected.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If Ozempic isn\u2019t refrigerated properly, the medication may become unsafe for use or increase the risk of <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8326694\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">side effects<\/span><\/a><span style=\"font-weight: 400;\"> of Ozempic when improperly kept outside the recommended temperature conditions.\u00a0<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/safe-medication-storage-home-children\/\"><b>Medication storage ideas<\/b><\/a><\/p>\n<p><span style=\"font-weight: 400;\">\u201cFreezing, excessive heat or high temperature, and sunlight can damage the Ozempic medication, leaving the medication ineffective,\u201d explains <\/span><a href=\"https:\/\/brio-medical.com\/team\/dr-nathan-goodyear-md\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Nathan Goodyear<\/span><\/a><span style=\"font-weight: 400;\">, MD, medical director of Brio-Medical in Scottsdale, Arizona.\u00a0<\/span><\/p>\n<h2 id=\"how-to-store-ozempic\"><span style=\"font-weight: 400;\">How to store Ozempic<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">To ensure proper storage of Ozempic, you should follow a few basic rules:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Before opening a new pen, keep it in the refrigerator between 36 F and 46 F.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">After first use, keep it refrigerated or at room temperature between 59 F and 86 F.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Never freeze Ozempic or expose it to excessive heat.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Keep the medication in a dry, dim place. Don\u2019t expose it to direct sunlight.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ensure the pen cap is fully closed after taking each dose of Ozempic.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Safely remove and dispose of the needle after taking your <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/ozempic-0-25-or-0-5-mg-dose\/dosage\"><span style=\"font-weight: 400;\">weekly Ozempic injection<\/span><\/a><span style=\"font-weight: 400;\">. Never store the Ozempic pen with an injection needle attached to it.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dispose of Ozempic when it has been open for longer than 56 days, or it has reached its expiration date.\u00a0<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">\t\t<div class=\"singlecare-dynamic-newsletter-wrapper sin-newsletter-wrapper\">\n\t\t\t<span class=\"heading\">Get our weight management newsletter<\/span>\n\t\t\t<form class=\"form-wrapper\" data-newsletter-form=\"1\" data-subsource=\"Weight Management Newsletter\">\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<label for=\"dynamic-email\">Email<\/label>\n\t\t\t\t\t<input type=\"email\" id=\"dynamic-email\" class=\"email\" required>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<input class=\"submit-form-btn\" type=\"submit\" value=\"Click to sign up\">\n\t\t\t\t<\/div>\n\t\t\t<\/form>\n\t\t\t<p class=\"success-message\" aria-live=\"polite\"><\/p>\n\t\t<\/div>\n\t<\/span><\/p>\n<h2 id=\"how-to-store-wegovy\"><span style=\"font-weight: 400;\">How to store Wegovy<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Wegovy <a href=\"https:\/\/www.novo-pi.com\/wegovy.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">storage recommendations<\/span><\/a><span style=\"font-weight: 400;\"> are slightly different than Ozempic:<\/span><\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Before opening a new pen, keep it in the refrigerator between 36 F and 46 F or, if needed, you may store it outside of the refrigerator between 46 F and 86 F for up to 28 days.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Never freeze Wegovy or expose it to excessive heat.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Keep the medication in a dry, dim place in its original carton. Don\u2019t expose it to direct sunlight.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Safely remove and dispose of the pen after taking your <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/wegovy\/dosage\"><span style=\"font-weight: 400;\">weekly Wegovy injection<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Discard the Wegovy pen after use, or it has reached the expiration date.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">If you are concerned your semaglutide pen has not been stored properly, speak with your healthcare professional or pharmacist about what to do.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>You\u2019ve likely heard about Ozempic (semaglutide), a glucagon-like peptide-1 (GLP-1) receptor agonist approved by the Food &amp; Drug Administration (FDA) to manage blood sugar levels for people with Type 2 diabetes. It gained approval in 2017 but has surged in popularity recently due to the medication\u2019s ability to help with weight loss. Ozempic can be [&hellip;]<\/p>\n","protected":false},"author":94,"featured_media":60894,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[8029],"tags":[10298,788,21067,9825],"coauthors":[20972],"class_list":["post-61239","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health-education","tag-diabetes","tag-drug-safety","tag-glp-1-drugs","tag-weight-loss","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Do Ozempic and Wegovy need to be refrigerated?<\/title>\n<meta name=\"description\" content=\"It&#039;s best to store Ozempic and Wegovy in the refrigerator, but some exceptions apply. 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