{"id":61468,"date":"2023-11-13T09:30:24","date_gmt":"2023-11-13T14:30:24","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=61468"},"modified":"2024-10-25T10:26:44","modified_gmt":"2024-10-25T14:26:44","slug":"how-long-does-it-take-for-ibuprofen-to-work","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/how-long-does-it-take-for-ibuprofen-to-work\/","title":{"rendered":"How long does it take ibuprofen to work?"},"content":{"rendered":"<p><a href=\"https:\/\/www.singlecare.com\/prescription\/ibuprofen\"><span style=\"font-weight: 400;\">Ibuprofen<\/span><\/a><span style=\"font-weight: 400;\"> is a nonsteroidal anti-inflammatory drug (<\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/nsaids\"><span style=\"font-weight: 400;\">NSAID<\/span><\/a><span style=\"font-weight: 400;\">) that is available over the counter (OTC) and by prescription in higher doses. Commonly referred to by brand names <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/advil\"><span style=\"font-weight: 400;\">Advil<\/span><\/a><span style=\"font-weight: 400;\"> and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/motrin-ib\"><span style=\"font-weight: 400;\">Motrin<\/span><\/a><span style=\"font-weight: 400;\">, ibuprofen works by reducing hormone-like substances called prostaglandins that cause pain and inflammation in the body. After administration, you should start feeling relief from symptoms as quickly as 20-30 minutes&mdash;depending on the form of medication you take and what you&rsquo;re treating.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Ibuprofen is often taken for discomforts such as period pain, fever, <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/rheumatoid-arthritis-symptoms\"><span style=\"font-weight: 400;\">rheumatoid arthritis<\/span><\/a><span style=\"font-weight: 400;\">, back pain, and migraines. The time it takes for ibuprofen to work depends on the formulation, the route of administration, and whether you&rsquo;re treating pain, fever, or inflammation. Here&rsquo;s what to expect.<\/span><\/p>\n<h2 id=\"how-long-does-it-take-for-ibuprofen-to-work\"><span style=\"font-weight: 400;\">How long does it take for ibuprofen to work?&nbsp;<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">&ldquo;After taking ibuprofen, someone should have relief or at least an easing of their pain or fever within 20 to 30 minutes,&rdquo; says <\/span><a href=\"https:\/\/wexnermedical.osu.edu\/find-a-doctor\/barbara-bawer-md-79613\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Barbara Bawer<\/span><\/a><span style=\"font-weight: 400;\">, MD, family medicine physician at The Ohio State University Wexner Medical Center. &ldquo;It does this by decreasing prostaglandin production, chemicals that trigger pain, fever, and inflammation in the body.&rdquo; If you are taking ibuprofen for conditions caused by inflammation, it can take a couple of weeks for full relief.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">How quickly ibuprofen works is also impacted by the type you are taking:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Oral tablets:<\/b><span style=\"font-weight: 400;\"> After being taken orally, ibuprofen should begin to work in 20-30 minutes. Peak blood levels occur at approximately 120 minutes. The anti-inflammatory effects can be expected to last for four to six hours, and the medication typically exits the system within a day.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Oral suspensions: <\/b><span style=\"font-weight: 400;\">These formulations will typically start to relieve pain in approximately 20 minutes and can be expected to last for four to six hours. Peak blood levels occur <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/fda\/fdaDrugXsl.cfm?setid=38ebacc3-378f-483e-babc-76119677e7df&amp;type=display\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">within one to two hours<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Topical patches or creams: <\/b><span style=\"font-weight: 400;\">Topical patches or creams will typically start to relieve pain in a day or two, says Dr. Bawer.<\/span><\/li>\n<\/ul>\n<h2 id=\"what-can-affect-how-long-it-takes-to-work\"><span style=\"font-weight: 400;\">What can affect how long it takes to work?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">There are a few factors that can affect how long it takes ibuprofen to work, including:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Age:<\/b> <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1884260\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Older adults<\/span><\/a><span style=\"font-weight: 400;\"> may be more sensitive to ibuprofen due to slower clearance of the drug from the body, while <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4355401\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">children under 5<\/span><\/a><span style=\"font-weight: 400;\"> generally process the drug more quickly. However, very young infants, especially premature ones, have a much slower clearance rate, which means the effects of ibuprofen may last longer in their bodies.&nbsp;<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Weight:<\/b><span style=\"font-weight: 400;\"> Ibuprofen may distribute more widely throughout the body of <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/4052122\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">people with obesity<\/span><\/a><span style=\"font-weight: 400;\">. However, individuals with obesity typically feel ibuprofen&#8217;s effects in the same amount of time as those of average weight.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Food: <\/b><span style=\"font-weight: 400;\">Taking ibuprofen after eating will slow the absorption rate slightly. Taking ibuprofen on an empty stomach might result in faster pain relief, but some people are more likely to experience common side effects of ibuprofen, such as nausea\/vomiting, indigestion, and stomach pain, on an empty stomach. However, gastrointestinal issues may be reduced when ibuprofen is taken with food, milk, or antacids.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Always tell your pharmacist or provider all of the medications and supplements you are taking and read all the labels and pharmacy instructions before taking ibuprofen with any other medications.<\/span><\/p>\n<h2 id=\"what-is-the-standard-ibuprofen-dosage\"><span style=\"font-weight: 400;\">What is the standard ibuprofen dosage?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Ibuprofen dosage varies depending on your age and existing medical conditions.<\/span><\/p>\n<h3 id=\"adult-dosages\"><span style=\"font-weight: 400;\">Adult dosages<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">For adults, the typical ibuprofen dose is <\/span><a href=\"https:\/\/reference.medscape.com\/drug\/advil-motrin-ibuprofen-343289\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">200 mg to 400 mg<\/span><\/a><span style=\"font-weight: 400;\"> up to four times daily. However, this can vary based on treatment needs or age. For example, certain conditions such as osteoarthritis may require higher doses.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">For adults with no medical issues, the maximum dosage in 24 hours is 3,200 mg, but it may be lower if you have health problems like heart disease, stomach ulcers, or kidney disease, according to Dr. Bawer.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">When determining a course of treatment, it&rsquo;s important to consider the reason for taking ibuprofen. For example, while short-term conditions such as headaches may need only a one-time pill, ibuprofen may need to be taken every four to six hours for a few days to treat something like a muscle injury, notes Dr. Bawer.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">While it is highly unlikely for someone to be taking ibuprofen daily for a full year, by doing so, your risk of developing stomach ulcers and kidney disease increases; it can also worsen liver and heart disease, according to Dr. Bawer.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">You should always start with the lowest possible dose for the shortest amount of time to relieve your symptoms. If chronic pain or inflammation persist after a few months of therapy, talk to your healthcare provider about exploring a different class of NSAID or gastrointestinal protection medicine such as a protein pump inhibitor.<\/span><\/p>\n<h3 id=\"childrens-dosages\"><span style=\"font-weight: 400;\">Children&rsquo;s dosages<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Children older than 2 can also be given ibuprofen as a pain reliever or fever reducer, but they generally take <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28516288\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">lower doses<\/span><\/a><span style=\"font-weight: 400;\"> that are often based on weight. Typically children can take 10 mg per kg of weight every six to eight hours, up to 40 mg per kg per day&mdash;but always consult with your pediatrician first.<\/span><\/p>\n<h2 id=\"who-should-avoid-taking-ibuprofen\"><span style=\"font-weight: 400;\">Who should avoid taking ibuprofen?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">While ibuprofen is an over-the-counter drug, there are a few factors that you should take into consideration before taking it.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">According to Dr. Bawer, you should <\/span><a href=\"https:\/\/fda.gov\/drugs\/postmarket-drug-safety-information-patients-and-providers\/ibuprofen-drug-facts-label\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">avoid taking ibuprofen<\/span><\/a><span style=\"font-weight: 400;\"> or speak with a healthcare provider if you:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Have allergies to ibuprofen<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Have had an allergic reaction to other NSAIDs such as <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/naproxen\"><span style=\"font-weight: 400;\">naproxen<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Are pregnant<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Have had recent surgery, peptic ulcer disease, or heartburn<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Are using other NSAIDs at the same time<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Are taking medications such as blood thinners, steroids, or blood pressure medications<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">If you have health conditions such as <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/news\/heart-disease-statistics\/\"><span style=\"font-weight: 400;\">heart disease<\/span><\/a><span style=\"font-weight: 400;\">, kidney or liver disease, or asthma, it&rsquo;s best to talk to your healthcare provider before taking ibuprofen. Ibuprofen may increase the risk of kidney problems, liver dysfunction, breathing problems, and heart attacks&mdash;especially in older adults with these conditions.<\/span><\/p>\n<h2 id=\"the-bottom-line\"><span style=\"font-weight: 400;\">The bottom line<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Knowing that ibuprofen can begin to provide relief from common pains from sprains to toothaches in as little as 20-30 minutes&mdash;depending on the delivery method&mdash;can be helpful when these ailments arise.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">While ibuprofen is generally considered safe, there are several considerations to take into account, including allergies, other medications, and stomach conditions when taking this medication. If you have any questions, discuss them with your healthcare provider or pharmacist.&nbsp;<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is available over the counter (OTC) and by prescription in higher doses. Commonly referred to by brand names Advil and Motrin, ibuprofen works by reducing hormone-like substances called prostaglandins that cause pain and inflammation in the body. After administration, you should start feeling relief from symptoms as [&hellip;]<\/p>\n","protected":false},"author":135,"featured_media":61321,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[20955,10708,808,8905],"coauthors":[12463],"class_list":["post-61468","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-inflammation","tag-over-the-counter-medications","tag-pain-management","tag-seasonal","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>How long does it take for ibuprofen to work?<\/title>\n<meta name=\"description\" content=\"You should start to notice the effects of oral ibuprofen within 20-30 minutes of use. 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