{"id":61557,"date":"2023-11-15T09:30:09","date_gmt":"2023-11-15T14:30:09","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=61557"},"modified":"2025-10-30T16:44:25","modified_gmt":"2025-10-30T20:44:25","slug":"is-cephalexin-a-strong-antibiotic","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/is-cephalexin-a-strong-antibiotic\/","title":{"rendered":"Is cephalexin a strong antibiotic?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Your ear has been throbbing for days. Perhaps you have a hacking cough that just won\u2019t go away. Or, you experience a burning sensation when you urinate. One trip to the doctor and a diagnosis later, you\u2019re walking out of the office with a prescription for cephalexin in hand.\u00a0<\/span><\/p>\n<p><span data-sheets-root=\"1\" data-sheets-value=\"{&quot;1&quot;:2,&quot;2&quot;:&quot;&quot;}\" data-sheets-userformat=\"{&quot;2&quot;:6849,&quot;3&quot;:{&quot;1&quot;:0},&quot;9&quot;:1,&quot;10&quot;:2,&quot;12&quot;:0,&quot;14&quot;:{&quot;1&quot;:2,&quot;2&quot;:0},&quot;15&quot;:&quot;Arial&quot;}\" data-sheets-formula=\"=CONCATENATE(R[0]C[-2],R[0]C[-3],R[0]C[-1])\"><\/span><\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/cephalexin\"><span style=\"font-weight: 400;\">Cephalexin<\/span><\/a><span style=\"font-weight: 400;\"> (also known by the brand name Keflex) is an antibiotic from the <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/cephalosporins\"><span style=\"font-weight: 400;\">cephalosporin family<\/span><\/a><span style=\"font-weight: 400;\"> that is approved by the Food and Drug Administration (FDA) to treat a number of bacterial infections, including skin and tissue infections, respiratory tract infections, urinary tract infections (UTIs), and ear infections.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">This drug is often favored by healthcare providers because it is typically \u201cwell-tolerated\u201d by patients and has less toxicity than other classes of antibiotics, such as fluoroquinolones, according to <\/span><a href=\"https:\/\/faculty.utah.edu\/u6024742-HANNAH_N._IMLAY\/hm\/index.hml\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Hannah Imlay<\/span><\/a><span style=\"font-weight: 400;\">, MD, an assistant professor of infectious diseases at the University of Utah Health in Salt Lake City. All that said, how strong is cephalexin? And how quickly will it work to clear the infection?<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/cephalexin-vs-amoxicillin\/\"><b>Cephalexin vs. Amoxicillin<\/b><\/a><\/p>\n<h2 id=\"is-cephalexin-a-strong-antibiotic\"><span style=\"font-weight: 400;\">Is cephalexin a strong antibiotic?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Cephalexin is a first-generation cephalosporin and broad-spectrum antibiotic that is effective against a <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK549780\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">number of pathogens<\/span><\/a><span style=\"font-weight: 400;\"> including <\/span><i><span style=\"font-weight: 400;\">Streptococcus pneumonia, Staphylococcus aureus<\/span><\/i><span style=\"font-weight: 400;\">, and <\/span><i><span style=\"font-weight: 400;\">Streptococcus pyogenes<\/span><\/i><span style=\"font-weight: 400;\">. These bacteria cause common ailments, including <\/span><a href=\"https:\/\/hhs.iowa.gov\/cade\/disease-information\/streptococcus-pneumoniae\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">middle ear infections<\/span><\/a><span style=\"font-weight: 400;\"> (otitis media), genitourinary tract infections, <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/6364089\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">skin infections<\/span><\/a><span style=\"font-weight: 400;\">, soft tissue infections, respiratory infections, and bone infections.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">However, there are some notable exceptions. \u201cIt doesn&#8217;t cover some stronger bugs, like MRSA [Methicillin-resistant Staphylococcus aureus] or some stronger staph infections or pseudomonas,\u201d says <\/span><a href=\"https:\/\/www.familymedicine.pitt.edu\/people\/gregory-castelli-pharmd\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Greg Castelli<\/span><\/a><span style=\"font-weight: 400;\">, Pharm.D., <\/span><span style=\"font-weight: 400;\">director of academic and clinical pharmacy in the Department of Family Medicine at the University of Pittsburgh School of Medicine.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Your healthcare professional may take a culture to ensure that your infection is caused by a type of bacteria that is susceptible to cephalexin. Like other antibiotics, cephalexin does not help treat the common cold, flu, COVID-19, or other types of viral infections.\u00a0<\/span><\/p>\n\t\t<div id=\"coupon-cta\" class=\"coupon-cta master-template\">\n\t\t\t<p id=\"headline\">Save up to 80% on Cephalexin with SingleCare<\/p>\n\t\t\t<p id=\"subheadline\">Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t<div class=\"details-wrap\">\n\t\t\t\t<div class=\"details\">\n\t\t\t\t\tCephalexin 500 mg (28 Capsule)\t\t\t\t<\/div>\n\t\t\t\t<div class=\"address\">\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"api-response\">\n\t\t\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-walmart-nbh-market.svg\" alt=\"Walmart Neighborhood Market\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$8.68<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/cephalexin#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/cephalexin#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-walmart.svg\" alt=\"Walmart Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$8.68<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/cephalexin#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/cephalexin#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/cephalexin#blog-cta\" class=\"coupon-see-all-btn\">See Cephalexin prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n<h2 id=\"how-quickly-does-cephalexin-work\"><span style=\"font-weight: 400;\">How quickly does cephalexin work?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Cephalexin starts working within <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK549780\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">one hour<\/span><\/a><span style=\"font-weight: 400;\"> of taking the first dose. However, it takes a little bit longer to notice the difference in your symptoms, which is in indication that the bacterial infection is going away. This prescription drug works by inhibiting the growth of bacteria, according to Dr. Castelli. Depending on the type of infection you have, you may start feeling better as soon as the next day after starting treatment. Other more severe infections may take longer.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If you\u2019re not feeling better after the entire course of your antibiotic, you should call your healthcare provider. And even if you do start feeling better before you\u2019ve finished your prescription, it\u2019s important to take the entire course of the antibiotic to ensure the infection is gone and to prevent <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/finish-antibiotics\/\"><span style=\"font-weight: 400;\">antibiotic resistance<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h2 id=\"how-is-cephalexin-used\"><span style=\"font-weight: 400;\">How is cephalexin used?<\/span><\/h2>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/cephalexin\/what-is\"><span style=\"font-weight: 400;\">Cephalexin<\/span><\/a><span style=\"font-weight: 400;\"> comes in three oral dosage forms: <\/span><a href=\"https:\/\/www.mayoclinic.org\/drugs-supplements\/cephalexin-oral-route\/description\/drg-20073325\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">capsule, tablet, and liquid<\/span><\/a><span style=\"font-weight: 400;\">. Dosage depends on age. For children ages 1 year to 15 years old, the dose is based on body weight. For adults, the typical dose is between 250 mg to 500 mg, taken up to four times a day (though it might be as low as twice a day), for <\/span><a href=\"https:\/\/medlineplus.gov\/druginfo\/meds\/a682733.html\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">seven to 14 days<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Consistent dosing is particularly important for cephalexin. \u201cYou have to keep a certain amount of the drug in your body to consistently have that bacteria-killing effect,\u201d Dr. Castelli explains. \u201cFor most infections, four times a day is what you need.\u201d\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In the case of a missed dose, if only a couple of hours have passed, it\u2019s okay to take it when you remember, according to Dr. Castelli. But if you\u2019re close to your next dose, simply wait until then and resume normal dosing. Do not double up on medication to try to make up for a missed dose.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Cephalexin can be taken with or without food. If you experience abdominal pain or any stomach problems while on the drug (which is common for many antibiotics), take it with a light snack, such as yogurt, which will also provide probiotic benefits to help regulate your gut bacteria.\u00a0<\/span><\/p>\n<h2 id=\"side-effects-of-cephalexin\"><span style=\"font-weight: 400;\">Side effects of cephalexin<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Common side effects of cephalexin include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Vomiting<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diarrhea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Yeast infection (either vaginal or oral)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fatigue<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Headache<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">If you\u2019re experiencing heavy diarrhea (five or more times a day), Dr. Imlay recommends contacting your healthcare provider, as that could be a sign of a <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/clostridium-difficile-treatment-and-medications\"><span style=\"font-weight: 400;\">Clostridioides difficile infection<\/span><\/a><span style=\"font-weight: 400;\"> (also known as C. diff). Other symptoms may include stomach pain, fever, and bloody or watery stools. A C. diff infection can cause colitis and damage the colon, so it\u2019s important to get quick treatment. These infections can occur while taking an antibiotic, or even up to several months after finishing the antibiotic.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If you experience any of the following adverse effects, which may indicate an allergic reaction or hypersensitivity to cephalexin, you should seek emergency medical attention immediately:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Skin rash or hives<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Swelling of the face or mouth<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Trouble breathing or swallowing<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">If you\u2019re worried about any of your side effects or if you are still not feeling well after you\u2019ve taken the entire prescription, contact your healthcare provider. <\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/cephalexin-alternatives\/\"><b>Cephalexin alternatives<\/b><\/a><\/p>\n<h2 id=\"what-should-i-avoid-while-taking-cephalexin\"><span style=\"font-weight: 400;\">What should I avoid while taking cephalexin?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">While cephalexin has fewer drug interactions than other antibiotics, there are a handful to be aware of. Tell your healthcare provider about all the medications you take, including prescription drugs, over-the-counter medicines, and vitamins or dietary supplements before taking cephalexin. Some interactions include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/metformin\"><b>Metformin<\/b><\/a><b>:<\/b><span style=\"font-weight: 400;\"> Co-administration of the Type 2 diabetes drug and cephalexin resulted in increased plasma concentration and decreased renal clearance of metformin, according to<\/span> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12222753\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">one study<\/span><\/a><span style=\"font-weight: 400;\">.<\/span> <span style=\"font-weight: 400;\">This means that metformin levels could build up in the body, which could increase the drug\u2019s blood sugar-lowering effects and\/or side effects.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/probenecid\"><b>Probenecid<\/b><\/a><b>:<\/b><span style=\"font-weight: 400;\"> The uric-acid reducer <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2006\/050405s097lbl.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">inhibits the renal excretions <\/span><\/a><span style=\"font-weight: 400;\">of cephalexin, meaning that cephalexin levels in the body can increase, potentially causing worsened side effects.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/warfarin-sodium\"><b>Warfarin<\/b><\/a><b>:<\/b><span style=\"font-weight: 400;\"> Cephalexin can affect your levels while on blood thinners, increasing the risk of bleeding. \u201cThe reason is that the concentration of blood thinners depends on the bacteria in your gut,\u201d Dr. Imlay says.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Zinc: <\/b><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3370346\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Studies<\/span><\/a><span style=\"font-weight: 400;\"> have found that this supplement may reduce the absorption rate of cephalexin. It\u2019s advised that you allow at least three hours to pass after a cephalexin dose before taking zinc.\u00a0<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">You should also alert your healthcare provider if you have renal issues, such as kidney disease, as they may change your dosage, says Dr. Castelli. \u201cAntibiotics can tend to hang out longer [in your body] if you have kidney dysfunction,\u201d he says.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Caution should be taken if you are breastfeeding, as cephalexin will be present in your breast milk. (There aren\u2019t adequate studies on the effect of cephalexin in pregnant women, so it\u2019s advised to take it only when necessary.) Always check with your provider if you are pregnant, planning to become pregnant, or breastfeeding.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Cephalexin should not be taken if you are allergic to cephalosporin antibiotics. In addition, seek medical advice if you are allergic to penicillin. In some cases, cephalexin is an alternative option if a patient is allergic to penicillin. In other cases, because the two families of drugs are closely related, there is also a chance of cross-reactivity (i.e., being allergic to both drugs).<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/cephalexin-interactions-to-avoid\/\"><b>Cephalexin interactions to avoid<\/b><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Your ear has been throbbing for days. Perhaps you have a hacking cough that just won\u2019t go away. Or, you experience a burning sensation when you urinate. One trip to the doctor and a diagnosis later, you\u2019re walking out of the office with a prescription for cephalexin in hand.\u00a0 Cephalexin (also known by the brand [&hellip;]<\/p>\n","protected":false},"author":94,"featured_media":61554,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[715],"coauthors":[8215],"class_list":["post-61557","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-antibiotics","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Is cephalexin a strong antibiotic?<\/title>\n<meta name=\"description\" content=\"Cephalexin is a broad-spectrum antibiotic that is effective against a variety of infections. 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