{"id":62019,"date":"2023-12-06T13:43:28","date_gmt":"2023-12-06T18:43:28","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=62019"},"modified":"2024-10-25T10:22:13","modified_gmt":"2024-10-25T14:22:13","slug":"rooster-comb-injections","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/rooster-comb-injections\/","title":{"rendered":"What is a rooster comb injection?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Rooster comb injections may sound medieval, but they are a fascinating, research-proven treatment for knee arthritis. Stiff, achy knees are a bane to so many of us, that it was welcome news when a new treatment option was approved 30 years ago, promising to reduce arthritis pain by injecting a lubricating fluid into the joints. The premise is termed <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/viscosupplements\"><span style=\"font-weight: 400;\">viscosupplementation<\/span><\/a>,<span style=\"font-weight: 400;\"> based on adding more viscous fluid to the joint space, and since initially released, product options have certainly expanded. What this all has to do with roosters and what exact benefits and risks the infections involve are some of the topics we will fill you in on.<\/span><\/p>\n<h2 id=\"what-is-a-rooster-comb-injection\"><span style=\"font-weight: 400;\">What is a rooster comb injection?&nbsp;<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The floppy, red comb of a rooster adorns the bird&rsquo;s head and is made of hyaluronic acid. That same substance is found in our joints, functioning as a lubricant and shock absorber. Extracting hyaluronate from the rooster&rsquo;s comb or synthesizing it in a lab provides the active ingredient for viscosupplements. The term &ldquo;rooster comb injection&rdquo; is now applied to this class of therapeutics, even if a product does not get its substrate from a chicken. Products in the class include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/supartz-fx\"><span style=\"font-weight: 400;\">Supartz Fx<\/span><\/a><span style=\"font-weight: 400;\"> (sodium hyaluronate)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/euflexxa\"><span style=\"font-weight: 400;\">Euflexxa<\/span><\/a><span style=\"font-weight: 400;\"> (sodium hyaluronate)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/gelsyn-3\"><span style=\"font-weight: 400;\">Gelsyn-3<\/span><\/a><span style=\"font-weight: 400;\"> (sodium hyaluronate)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/durolane\"><span style=\"font-weight: 400;\">Durolane<\/span><\/a><span style=\"font-weight: 400;\"> (sodium hyaluronate)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/synvisc\"><span style=\"font-weight: 400;\">Synvisc<\/span><\/a><span style=\"font-weight: 400;\"> (hylan gf-20)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/synvisc-one\"><span style=\"font-weight: 400;\">Synvisc-One<\/span><\/a><span style=\"font-weight: 400;\"> (hylan gf-20)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/genvisc-850\"><span style=\"font-weight: 400;\">Genvisc 850<\/span><\/a><span style=\"font-weight: 400;\"> (sodium hyaluronate)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/hyalgan\"><span style=\"font-weight: 400;\">Hyalgan<\/span><\/a><span style=\"font-weight: 400;\"> (sodium hyaluronate)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/monovisc\"><span style=\"font-weight: 400;\">Monovisc<\/span><\/a><span style=\"font-weight: 400;\"> (high molecular weight hyaluronan)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/orthovisc\"><span style=\"font-weight: 400;\">Orthovisc<\/span><\/a><span style=\"font-weight: 400;\"> (high molecular weight hyaluronan)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/triluron\"><span style=\"font-weight: 400;\">Triluron<\/span><\/a><span style=\"font-weight: 400;\"> (sodium hyaluronate)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/trivisc\"><span style=\"font-weight: 400;\">Trivisc<\/span><\/a><span style=\"font-weight: 400;\"> (sodium hyaluronate)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/visco-3\"><span style=\"font-weight: 400;\">Visco-3<\/span><\/a><span style=\"font-weight: 400;\"> (sodium hyaluronate)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">By injecting a viscosupplement into the synovial fluid of a joint with osteoarthritis, the hope is that the worn-down cartilage of the joint glides more smoothly and less painfully. The simple injection procedure is done in a medical office by a primary care, orthopedic, or sports medicine provider. Using sterile methods, a needle is inserted into the joint space in order to inject the viscosupplement. It takes just a minute, and you can return home afterward.<\/span><\/p>\n<h2 id=\"who-can-benefit-from-rooster-comb-injections\"><span style=\"font-weight: 400;\">Who <\/span><span style=\"font-weight: 400;\">can benefit from rooster comb injections?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Hyaluronic acid injections, or rooster comb injections as they are often called, are only approved by the Food and Drug Administration (FDA) for use in <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/living-with-osteoarthritis\/\"><span style=\"font-weight: 400;\">osteoarthritis<\/span><\/a><span style=\"font-weight: 400;\"> of the knee joint. Other forms of arthritis, such as <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/osteoarthritis-vs-rheumatoid-arthritis\/\"><span style=\"font-weight: 400;\">rheumatoid<\/span><\/a><span style=\"font-weight: 400;\"> and psoriatic arthritis, and other joints are not included in the indication. That may sound like a limiting factor for its use, but when you consider that osteoarthritis is the <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/news\/arthritis-statistics\/\"><span style=\"font-weight: 400;\">most common type of arthritis<\/span><\/a><span style=\"font-weight: 400;\"> and the knee joint is most often affected, it becomes clear that rooster comb injections can potentially benefit a vast number of people.<\/span><\/p>\n<h2 id=\"how-long-do-rooster-comb-injections-last\"><span style=\"font-weight: 400;\">How long do rooster comb injections last?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Improvements in joint pain and stiffness may last six months. However, we should back up a bit to get our expectations in check. Not everyone improves after rooster comb shots. In fact, <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26677239\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">clinical studies<\/span><\/a><span style=\"font-weight: 400;\"> and expert guidelines are split on whether this modality is sufficiently effective and advisable. You will want to get the medical advice of your primary care provider or orthopedic surgeon for help in determining if rooster comb injections are right for you.<\/span><\/p>\n<h2 id=\"what-are-the-side-effects-of-rooster-injections\"><span style=\"font-weight: 400;\">What are the side effects of rooster injections?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Putting these shots into a joint is meant to provide pain relief, but the potential side effects include pain, swelling, and redness at the site. These types of local immune reactions can occur with other types of joint injections, so it is a phenomenon that is not unique to rooster comb injections. Systemic immune reactions can create general achiness, but they can also amount to full-blown hypersensitivity with allergic reactions. To lessen this risk, anyone with a history of bird protein, feathers, or eggs may need to avoid viscosupplements.<\/span><\/p>\n<h2 id=\"how-much-do-rooster-comb-injections-cost\"><span style=\"font-weight: 400;\">How much do rooster comb injections cost?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">As you might imagine, the price of rooster comb shots varies depending on the product. Some products are given as a weekly injection for three to five weeks, while others are only given once. For example, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/supartz-fx\/what-is\"><span style=\"font-weight: 400;\">Supartz FX<\/span><\/a><span style=\"font-weight: 400;\"> is injected every week for five weeks, but <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/durolane\/what-is\"><span style=\"font-weight: 400;\">Durolane<\/span><\/a><span style=\"font-weight: 400;\"> is given one time. The total cost of a treatment course usually ends up being fairly similar, ranging between about $1200 and $1800. Courses of injections are sometimes repeated after six months or more. A <\/span><a href=\"https:\/\/www.singlecare.com\/prescription-discount-card\"><span style=\"font-weight: 400;\">SingleCare discount card<\/span><\/a><span style=\"font-weight: 400;\"> can help keep the costs from piling up too much.<\/span><\/p>\n<h2 id=\"frequently-asked-questions-about-rooster-comb-injections\"><span style=\"font-weight: 400;\">Frequently asked questions about rooster comb injections<\/span><\/h2>\n<h3 id=\"what-are-rooster-comb-injections-made-from\"><span style=\"font-weight: 400;\">What are rooster comb injections made from?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Hyaluronic acid is the key ingredient in viscosupplement shots for knee arthritis. The substance allows joint surfaces to glide more smoothly, cushion impacts, and reduce inflammation. The hyaluronate was historically extracted and purified from the combs of roosters, but it can also be synthesized in laboratories.<\/span><\/p>\n<h3 id=\"is-rooster-comb-better-than-cortisone\"><span style=\"font-weight: 400;\">Is rooster comb better than cortisone?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Results of clinical trials are conflicted on whether viscosupplementation is better than cortisone injections, which are used for their anti-inflammatory properties in the setting of different types of arthritis and in various joints. Regarding knee osteoarthritis, <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8567800\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">some studies<\/span><\/a><span style=\"font-weight: 400;\"> have found rooster comb shots to be superior, and others have found them to be no better than <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/corticosteroids\"><span style=\"font-weight: 400;\">corticosteroid<\/span><\/a><span style=\"font-weight: 400;\"> shots. Other findings pointed out that viscosupplements may have longer-lasting benefits but not act as quickly as steroid injections.<\/span><\/p>\n<h3 id=\"is-synvisc-the-same-as-rooster-comb\"><span style=\"font-weight: 400;\">Is Synvisc the same as rooster comb?<\/span><\/h3>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/synvisc\/what-is\"><span style=\"font-weight: 400;\">Synvisc<\/span><\/a><span style=\"font-weight: 400;\"> is one of the brand-name hyaluronic acid products indicated by the FDA for knee osteoarthritis. Given as a three-dose series of injections, it is considered one of the &ldquo;rooster comb shots&rdquo; based on its active ingredient, hyaluronate. The manufacturer also has a single-dose version called <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/synvisc-one\/what-is\"><span style=\"font-weight: 400;\">Synvisc-One<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h3 id=\"does-medicare-cover-rooster-comb-injections-for-the-knee\"><span style=\"font-weight: 400;\">Does Medicare cover rooster comb injections for the knee?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">In general, <\/span><a href=\"https:\/\/www.cms.gov\/medicare-coverage-database\/view\/lcd.aspx?lcdid=33767&amp;ver=36&amp;\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Medicare<\/span><\/a><span style=\"font-weight: 400;\"> considers viscosupplement shots as medically reasonable and necessary for knee osteoarthritis when other conservation measures have been tried, such as physical therapy, nonsteroidal anti-inflammatory drugs (<\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/nsaids\"><span style=\"font-weight: 400;\">NSAIDs<\/span><\/a><span style=\"font-weight: 400;\">), and corticosteroid injections. According to <\/span><a href=\"https:\/\/www.synvisconehcp.com\/medicare\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Sanofi<\/span><\/a><span style=\"font-weight: 400;\">, the maker of Synvisc products, all local Medicare Administrative Contractors cover their products in these circumstances.<\/span><\/p>\n<h3 id=\"can-rooster-comb-injections-be-used-in-conjunction-with-other-treatments-or-medications\"><span style=\"font-weight: 400;\">Can rooster comb injections be used in conjunction with other treatments or medications?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Rooster comb injections do not need to stand alone as a treatment for osteoarthritis of the knee. They can be used in conjunction with corticosteroid shots, NSAIDs, <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/prp-injection\/\"><span style=\"font-weight: 400;\">platelet-rich plasma (PRP) injections<\/span><\/a><span style=\"font-weight: 400;\">, and physical therapy, but not all of these may be right for you. If these are ineffective, knee replacement is yet another option. Check with your team of healthcare professionals to find the optimal regimen for your knee pain.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Rooster comb injections may sound medieval, but they are a fascinating, research-proven treatment for knee arthritis. Stiff, achy knees are a bane to so many of us, that it was welcome news when a new treatment option was approved 30 years ago, promising to reduce arthritis pain by injecting a lubricating fluid into the joints. [&hellip;]<\/p>\n","protected":false},"author":133,"featured_media":62022,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[8029],"tags":[20955],"coauthors":[20732],"class_list":["post-62019","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health-education","tag-inflammation","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>What is a rooster comb injection, and is it right for you?<\/title>\n<meta name=\"description\" content=\"Discover the benefits, side effects, and cost of rooster comb injections. 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Learn if this treatment is right for you.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.singlecare.com\/blog\/rooster-comb-injections\/\" \/>\n<meta property=\"og:site_name\" content=\"The Checkup\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/singlecare\" \/>\n<meta property=\"article:published_time\" content=\"2023-12-06T18:43:28+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-10-25T14:22:13+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2023\/12\/rooster-comb-injections.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"1080\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Chad Shaffer, MD\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@SingleCare\" \/>\n<meta name=\"twitter:site\" content=\"@SingleCare\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Chad Shaffer, MD\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/rooster-comb-injections\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/rooster-comb-injections\\\/\"},\"author\":{\"name\":\"Christie Falzone\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#\\\/schema\\\/person\\\/5ff7c7bb5ce0c66a6962ecf7c8d7941e\"},\"headline\":\"What is a rooster comb injection?\",\"datePublished\":\"2023-12-06T18:43:28+00:00\",\"dateModified\":\"2024-10-25T14:22:13+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/rooster-comb-injections\\\/\"},\"wordCount\":1048,\"publisher\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/rooster-comb-injections\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2023\\\/12\\\/rooster-comb-injections.png\",\"keywords\":[\"Inflammation\"],\"articleSection\":[\"Health Education\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/rooster-comb-injections\\\/\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/rooster-comb-injections\\\/\",\"name\":\"What is a rooster comb injection, and is it right for you?\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/rooster-comb-injections\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/rooster-comb-injections\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2023\\\/12\\\/rooster-comb-injections.png\",\"datePublished\":\"2023-12-06T18:43:28+00:00\",\"dateModified\":\"2024-10-25T14:22:13+00:00\",\"description\":\"Discover the benefits, side effects, and cost of rooster comb injections. 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