{"id":62090,"date":"2023-12-12T13:45:42","date_gmt":"2023-12-12T18:45:42","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=62090"},"modified":"2024-10-25T10:21:42","modified_gmt":"2024-10-25T14:21:42","slug":"zolpidem-interactions","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/zolpidem-interactions\/","title":{"rendered":"Zolpidem interactions to avoid"},"content":{"rendered":"

Zolpidem tartrate<\/span><\/a>, better known by its brand names <\/span>Ambien<\/span><\/a> and <\/span>Ambien CR<\/span><\/a>, is a famed hypnotic for the treatment of insomnia. It became infamous for reports of sleepwalking and even sleep-driving behaviors by users. Recognition of these next-day events has led to greater caution with the drug’s use and dosing, and just as important, concerns involving <\/span>side effects<\/span><\/a> have called attention to drug interactions that can escalate adverse reactions. Learning more about zolpidem’s interactions with other medications, alcohol, and disease states could help to keep you out of harm’s way.<\/span><\/p>\n

Zolpidem drug interactions<\/span><\/h2>\n

Most of the interactions involving zolpidem fall into one of two categories, doubling up on drowsiness-inducing substances or affecting the drug’s metabolism. Otherwise, there are a couple of other notable interactions.<\/span><\/p>\n

Opioids<\/span><\/h3>\n

Opioid agonist pain relievers<\/span><\/a> commonly cause drowsiness. Combining them with other agents that induce sedation can be a recipe for disaster, with life-threatening reductions in breathing, <\/span>increased falls, and deaths. The Food and Drug Administration (FDA) even sent a <\/span> to call attention to this risk. For that reason, it is typically best to avoid combining opiates with zolpidem. Examples of opiates include:<\/span><\/p>\n