{"id":62193,"date":"2023-12-15T09:30:18","date_gmt":"2023-12-15T14:30:18","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=62193"},"modified":"2024-11-12T19:58:59","modified_gmt":"2024-11-13T00:58:59","slug":"does-zyrtec-make-you-drowsy","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/does-zyrtec-make-you-drowsy\/","title":{"rendered":"Does Zyrtec make you drowsy?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">You\u2019ve had itchy, watery eyes for days. Or maybe you can\u2019t stop sneezing. Desperate for help, you head to the store for meds that promise allergy relief. Chances are, you walk out with an over-the-counter (OTC) treatment like Zyrtec in hand.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Zyrtec is the brand name for <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/cetirizine-hcl\"><span style=\"font-weight: 400;\">cetirizine<\/span><\/a><span style=\"font-weight: 400;\">, an <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/antihistamines\"><span style=\"font-weight: 400;\">antihistamine<\/span><\/a><span style=\"font-weight: 400;\"> used to treat allergy symptoms like itchy eyes, runny nose, and sneezing. Like all antihistamine medications, it works by blocking the effects of histamines, natural substances the body produces in response to allergens. <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2003\/21150se8-002_zyrtec_lbl.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Zyrtec-D<\/span><\/a><span style=\"font-weight: 400;\">, a different option, combines cetirizine and the nasal decongestant pseudoephedrine.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">While Zyrtec is considered generally safe for most people, it may still cause side effects. The most common side effects of Zyrtec include drowsiness, dry mouth, and dizziness. So, will Zyrtec make you sleepy? And if so, how long will it take for the drowsiness to wear off?<\/span><\/p>\n<h2 id=\"does-zyrtec-make-you-drowsy\"><span style=\"font-weight: 400;\">Does Zyrtec make you drowsy?\u00a0<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Drowsiness is a common side effect of Zyrtec. In placebo-controlled clinical trials, <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2002\/19835s15,%2020346s8lbl.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">11% to 14%<\/span><\/a><span style=\"font-weight: 400;\"> of patients taking Zyrtec reported feeling sleepy after taking the medication.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Of course, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/cetirizine-hcl\/what-is\"><span style=\"font-weight: 400;\">Zyrtec<\/span><\/a><span style=\"font-weight: 400;\"> is not the only allergy medication that causes drowsiness. Older, first-generation antihistamines\u2014such as <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/benadryl-allergy\"><span style=\"font-weight: 400;\">Benadryl<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/diphenhydramine-hcl\"><span style=\"font-weight: 400;\">diphenhydramine<\/span><\/a><span style=\"font-weight: 400;\">) or <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/hydroxyzine-hcl\"><span style=\"font-weight: 400;\">hydroxyzine<\/span><\/a><span style=\"font-weight: 400;\">\u2014are even more likely to have sedative-like effects, explains <\/span><a href=\"https:\/\/www.harborhealth.com\/clinicians\/necessitatibus-magni-distinctio\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Jodie Pepin<\/span><\/a><span style=\"font-weight: 400;\">, Pharm.D., the clinical pharmacy program director at <\/span><a href=\"https:\/\/www.harborhealth.com\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Harbor Health<\/span><\/a><span style=\"font-weight: 400;\"> in Austin, Texas. Second-generation antihistamines were developed to be as effective with fewer or less severe side effects.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">According to Dr. Pepin, if you\u2019re one of the people who experience drowsiness from Zyrtec, you\u2019ll start feeling sleepy 60-90 minutes after taking it. This side effect can last up to eight hours, she adds.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In addition to drowsiness, other common <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/cetirizine-hcl\/what-is\"><span style=\"font-weight: 400;\">Zyrtec side effects<\/span><\/a><span style=\"font-weight: 400;\"> include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fatigue<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dry mouth<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sore throat<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Some less common side effects of Zyrtec include abdominal pain, diarrhea, and nosebleeds.<\/span><\/p>\n<h2 id=\"4-reasons-zyrtec-could-make-you-drowsy\"><span style=\"font-weight: 400;\">4 reasons Zyrtec could make you drowsy<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Although you may not be able to fully control cetirizine making you drowsy, there are four factors that impact the likelihood the medication will make you more sleepy.\u00a0<\/span><\/p>\n<ol>\n<li><b> You\u2019re taking a high dose. <\/b><span style=\"font-weight: 400;\">The higher your Zyrtec dose, the more likely you will experience adverse side effects. Zyrtec (cetirizine) is available in standard tablets (10 mg), liquid gels (10 mg), chewable tablets (2.5 mg and 10 mg), and syrup (1 mg per 1 mL). The recommended dose for most adults is 10 mg (one pill) per day. However, people older than 65 or with kidney or liver disease should consider reducing their dose to 5 mg daily, according to Dr. Pepin.\u00a0<\/span><\/li>\n<li><b> You\u2019re taking it in the morning. <\/b><span style=\"font-weight: 400;\">If you want to avoid daytime sleepiness from Zyrtec, take it at night, says Dr. Pepin. \u201cSince sedation can occur up to eight hours after taking a dose, taking it at bedtime will alleviate the daytime sleepiness that can occur if taken in the morning,\u201d she explains.\u00a0<\/span><\/li>\n<li><b> You\u2019re combining it with alcohol. <\/b><span style=\"font-weight: 400;\">Zyrtec and alcohol both have sedative-like effects. Combining the two can worsen drowsiness, cautions <\/span><a href=\"https:\/\/www.sjmed.com\/assets\/documents\/gme\/pharmacy-residency\/sjhs-pharmacy-residency-faculty-roster-2021.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Blair Gingerich<\/span><\/a><span style=\"font-weight: 400;\">, Pharm.D., a clinical care and retail pharmacist in northern Indiana.<\/span><\/li>\n<li><b> You\u2019re mixing it with other medications. <\/b><span style=\"font-weight: 400;\">Taking Zyrtec with medications that also cause drowsiness may amplify the effect overall, says Dr. Gingerich. Drugs known to cause drowsiness include <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/benzodiazepines\"><span style=\"font-weight: 400;\">benzodiazepines<\/span><\/a><span style=\"font-weight: 400;\"> (a type of anxiety medication), <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/opioids\"><span style=\"font-weight: 400;\">opioid pain medicines<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/sleep-aids-guide\/\"><span style=\"font-weight: 400;\">sleeping medications<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/best-muscle-relaxers\/\"><span style=\"font-weight: 400;\">muscle relaxants<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/anticonvulsants\"><span style=\"font-weight: 400;\">seizure medications<\/span><\/a><span style=\"font-weight: 400;\"> (such as <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/gabapentin\"><span style=\"font-weight: 400;\">gabapentin<\/span><\/a><span style=\"font-weight: 400;\">), and other CNS depressant medications (medicines that slow down the central nervous system).<\/span><\/li>\n<\/ol>\n<p><span style=\"font-weight: 400;\">\t\t<div class=\"singlecare-dynamic-newsletter-wrapper sin-newsletter-wrapper\">\n\t\t\t<span class=\"heading\">Get our allergies newsletter<\/span>\n\t\t\t<form class=\"form-wrapper\" data-newsletter-form=\"1\" data-subsource=\"Allergies Newsletter\">\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<label for=\"dynamic-email\">Email<\/label>\n\t\t\t\t\t<input type=\"email\" id=\"dynamic-email\" class=\"email\" required>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<input class=\"submit-form-btn\" type=\"submit\" value=\"Click to sign up\">\n\t\t\t\t<\/div>\n\t\t\t<\/form>\n\t\t\t<p class=\"success-message\" aria-live=\"polite\"><\/p>\n\t\t<\/div>\n\t<\/span><\/p>\n<h2 id=\"how-to-use-zyrtec-safely\"><span style=\"font-weight: 400;\">How to use Zyrtec safely<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Zyrtec is considered safe by the U.S. Food and Drug Administration (FDA) when proper dosage is followed. Always follow the instructions on the label for accurate dosing. The standard daily Zyrtec dosage depends on the age of the patient as well as the formulation<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Zyrtec is considered generally safe for <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/taking-antihistamines-daily\/\"><span style=\"font-weight: 400;\">long-term use<\/span><\/a><span style=\"font-weight: 400;\">. However, it\u2019s best to consult your healthcare provider about possible interactions with other medications or potential long-term side effects based on age and health conditions. Specifically, you should talk to your healthcare provider before taking Zyrtec if you are:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pregnant or planning to become pregnant<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Breastfeeding<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Living with kidney disease or liver disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Taking an allergy medicine for the first time<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Some people are allergic to one or more components of Zyrtec or generic cetirizine. If you experience signs of anaphylaxis, such as hives, swelling, or trouble breathing, call 911.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Once you have taken Zyrtec for allergy symptoms, Dr. Pepin recommends monitoring yourself to determine if you are one of the 14% of people who experience drowsiness. If you are, avoid driving or operating heavy machinery until you know how Zyrtec affects you. Because both Zyrtec and alcohol can cause excessive sleepiness, it\u2019s best to avoid drinking alcohol while taking Zyrtec.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If you do not want to take Zyrtec, or if you find that Zyrtec is not working for you, a primary care provider or allergist can offer medical advice about other medications for seasonal allergies, hay fever, or sinus issues. For example, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/claritin\"><span style=\"font-weight: 400;\">Claritin<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/loratadine\"><span style=\"font-weight: 400;\">loratadine<\/span><\/a><span style=\"font-weight: 400;\">), <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/allegra-allergy\"><span style=\"font-weight: 400;\">Allegra<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/fexofenadine-hcl\"><span style=\"font-weight: 400;\">fexofenadine<\/span><\/a><span style=\"font-weight: 400;\">), and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/xyzal-allergy-24hr\"><span style=\"font-weight: 400;\">Xyzal<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/levocetirizine-dihydrochloride\"><span style=\"font-weight: 400;\">levocetirizine<\/span><\/a><span style=\"font-weight: 400;\">) are all second-generation antihistamines. Or, you might need a nasal steroid, such as <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/flonase-allergy-relief\"><span style=\"font-weight: 400;\">Flonase<\/span><\/a><span style=\"font-weight: 400;\">, or an allergy eye drop, such as <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/pataday\"><span style=\"font-weight: 400;\">Pataday<\/span><\/a><span style=\"font-weight: 400;\">. If your allergy symptoms are severe, a healthcare provider can also offer guidance on prescription drugs or <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/allergy-shots\/\"><span style=\"font-weight: 400;\">allergy shots<\/span><\/a><span style=\"font-weight: 400;\"> for allergy relief.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>You\u2019ve had itchy, watery eyes for days. Or maybe you can\u2019t stop sneezing. Desperate for help, you head to the store for meds that promise allergy relief. Chances are, you walk out with an over-the-counter (OTC) treatment like Zyrtec in hand. Zyrtec is the brand name for cetirizine, an antihistamine used to treat allergy symptoms [&hellip;]<\/p>\n","protected":false},"author":135,"featured_media":62067,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[554,12752,8905,802],"coauthors":[20942],"class_list":["post-62193","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-allergies","tag-medication-side-effects","tag-seasonal","tag-seasonal-allergies","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Does Zyrtec make you drowsy?<\/title>\n<meta name=\"description\" content=\"Zyrtec causes drowsiness in up to 14% of people. 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