{"id":62350,"date":"2023-12-29T15:58:09","date_gmt":"2023-12-29T20:58:09","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=62350"},"modified":"2025-12-22T13:20:21","modified_gmt":"2025-12-22T18:20:21","slug":"buspirone-side-effects","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/buspirone-side-effects\/","title":{"rendered":"Buspirone side effects and how to avoid them"},"content":{"rendered":"<p><a href=\"https:\/\/www.singlecare.com\/prescription\/buspirone-hcl\"><span style=\"font-weight: 400;\">Buspirone<\/span><\/a><span style=\"font-weight: 400;\"> is a generic prescription drug that treats symptoms of <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/anxiety-treatment-and-medications\"><span style=\"font-weight: 400;\">anxiety disorders<\/span><\/a><span style=\"font-weight: 400;\">. Buspirone used to be sold under the brand name Buspar, which is no longer sold in the U.S. Although buspirone was originally developed as an antipsychotic, it was determined to be ineffective for psychosis. However, it works well as an <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/anxiolytics\"><span style=\"font-weight: 400;\">anxiolytic<\/span><\/a><span style=\"font-weight: 400;\"> (an anti-anxiety medication). Even though buspirone lacks the side effects of other anti-anxiety drugs, such as <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/benzodiazepines\"><span style=\"font-weight: 400;\">benzodiazepines<\/span><\/a><span style=\"font-weight: 400;\"> and <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/antidepressants\"><span style=\"font-weight: 400;\">antidepressants<\/span><\/a><span style=\"font-weight: 400;\">, it can cause certain side effects.\u00a0<\/span><\/p>\n<h2 id=\"why-was-buspar-taken-off-the-market\"><span style=\"font-weight: 400;\">Why was Buspar taken off the market?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Brand-name Buspar was taken off the market over a decade ago once generic buspirone became widely available. The Food and Drug Administration (FDA) found that Buspar <\/span><span style=\"font-weight: 400;\">did not cause any concerns<\/span><span style=\"font-weight: 400;\"> for safety or effectiveness.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\t\t<div id=\"coupon-cta\" class=\"coupon-cta master-template\">\n\t\t\t<p id=\"headline\">Save up to 80% on Buspirone with SingleCare<\/p>\n\t\t\t<p id=\"subheadline\">Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t<div class=\"details-wrap\">\n\t\t\t\t<div class=\"details\">\n\t\t\t\t\tBuspirone 5 mg (60 Tablets)\t\t\t\t<\/div>\n\t\t\t\t<div class=\"address\">\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"api-response\">\n\t\t\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-kroger.svg\" alt=\"Kroger Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$4.74<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/buspirone-hcl#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/buspirone-hcl#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-harristeeter.svg\" alt=\"Harris Teeter Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$4.74<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/buspirone-hcl#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/buspirone-hcl#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/buspirone-hcl#blog-cta\" class=\"coupon-see-all-btn\">See Buspirone prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t<\/span><\/p>\n<h2 id=\"what-are-the-side-effects-of-buspirone\"><span style=\"font-weight: 400;\">What are the side effects of buspirone?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Compared to most other anxiolytics, buspirone has fewer side effects.\u00a0<\/span><\/p>\n<h3 id=\"common-side-effects-of-buspirone\"><span style=\"font-weight: 400;\">Common side effects of buspirone<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=07a789a9-c9e8-4737-a56d-7d5405fe8100\"><span style=\"font-weight: 400;\">most common side effects of buspirone<\/span><\/a><span style=\"font-weight: 400;\"> are dizziness, drowsiness, nausea, headache, nervousness, and fatigue. Other side effects are reported in 3% or less of people who take buspirone. These side effects include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Insomnia<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lightheadedness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dry mouth<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Excitement\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Anger<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Confusion<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Blurred vision<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diarrhea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Increased heart rate, palpitations, and chest pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Muscle aches and pains<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Weakness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Numbness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Coordination problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tremor<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Skin rash<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sweating<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tinnitus<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sore throat and nasal congestion<\/span><\/li>\n<\/ul>\n<h3 id=\"serious-side-effects-of-buspirone\"><span style=\"font-weight: 400;\">Serious side effects of buspirone<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Serious side effects caused by buspirone are rare but can include the following:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Increased liver enzymes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Akathisia (intense restlessness)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Involuntary movements<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hallucinations<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/serotonin-syndrome-treatment-and-medications\"><span style=\"font-weight: 400;\">Serotonin syndrome<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/depression-treatment-and-medications\"><span style=\"font-weight: 400;\">Depression<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Seizures<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Suicidality<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Allergic reactions<\/span><\/li>\n<\/ul>\n<h3 id=\"does-buspirone-cause-sexual-side-effects\"><span style=\"font-weight: 400;\">Does buspirone cause sexual side effects?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">In clinical trials, buspirone sexual side effects were rare. The most common (incidence rates of approximately 0.1% to 1%) were decreased or increased libido. Rare side effects (less than\u00a0 0.01% incidence) included delayed ejaculation and impotence. For this reason, healthcare professionals use buspirone as an alternative to <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/ssris\"><span style=\"font-weight: 400;\">selective serotonin reuptake inhibitors (SSRIs)<\/span><\/a><span style=\"font-weight: 400;\"> and <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/snris\/\"><span style=\"font-weight: 400;\">serotonin-norepinephrine reuptake inhibitors (SNRIs)<\/span><\/a><span style=\"font-weight: 400;\">. If you experience buspirone side effects sexually, contact your healthcare provider, who can rule out other causes.\u00a0<\/span><\/p>\n<p><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/resources\/anxiety\"><b>Anxiety medication coupons and resources<\/b><\/a><\/p>\n<h3 id=\"does-buspirone-cause-weight-gain\"><span style=\"font-weight: 400;\">Does buspirone cause weight gain?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Weight gain is a rare side effect of buspirone, affecting only about 0.1% to 1% of people taking the drug. This number is so low that researchers aren\u2019t certain whether the weight gain in these patients is actually caused by buspirone. Again, this makes buspirone preferable to other anxiety drugs, such as antidepressants and benzodiazepines, which can cause weight gain in some people.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/news\/ssri-weight-gain-statistics\/\"><span style=\"font-weight: 400;\">SSRI weight gain statistics<\/span><\/a><\/p>\n<h2 id=\"does-buspirone-cause-nightmares\"><span style=\"font-weight: 400;\">Does buspirone cause nightmares?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Dream disturbances can occur when taking buspirone, but buspirone nightmares are a rare side effect. Buspirone can increase rapid eye movement (REM) sleep and shift its occurrence to later in the sleep cycle. There have also been limited reports of sleepwalking when starting buspirone, but it is uncertain if there is a direct cause. It is unclear exactly how buspirone affects sleep.<\/span><\/p>\n<h2 id=\"how-soon-do-buspirone-side-effects-start\"><span style=\"font-weight: 400;\">How soon do buspirone side effects start?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Buspirone side effects may begin as early as the first week of taking it, since the body is not accustomed to the drug. Healthcare professionals believe that side effects may abate as doses are gradually adjusted to the best dose.\u00a0<\/span><\/p>\n<h2 id=\"buspirone-side-effects-during-the-first-week\"><span style=\"font-weight: 400;\">Buspirone side effects during the first week<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The most common side effects of buspirone <\/span><a href=\"https:\/\/www.pdr.net\/drug-summary\/?drugLabelId=1524\"><span style=\"font-weight: 400;\">start early in treatment<\/span><\/a><span style=\"font-weight: 400;\"> and include dizziness, headache, nervousness, and nausea. In at least <\/span><a href=\"https:\/\/www.amjmed.com\/article\/0002-9343(86)90327-X\/pdf\"><span style=\"font-weight: 400;\">one study<\/span><\/a><span style=\"font-weight: 400;\">, most people taking buspirone rated their side effects as mild or moderate.\u00a0<\/span><\/p>\n<h2 id=\"how-long-do-buspirone-side-effects-last\"><span style=\"font-weight: 400;\">How long do buspirone side effects last?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Healthcare professionals have not studied how long buspirone\u2019s side effects last, but side effects typically subside as the body acclimates to the drug over the first few weeks of treatment. During clinical trials, at least 10% of participants dropped out due to side effects in the first three to four weeks. Most stopped taking buspirone because of problems like dizziness, headache, and nervousness.\u00a0<\/span><\/p>\n<h2 id=\"what-are-the-long-term-side-effects-of-buspirone\"><span style=\"font-weight: 400;\">What are the long-term side effects of buspirone?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The long-term use of buspirone is not associated with a greater risk of potential side effects. Additionally, buspirone is not associated with any long-term adverse effects. However, there have been rare reports of people experiencing movement disorders, such as twitching, grimacing, writhing, intense restlessness, and Parkinson\u2019s disease symptoms, as delayed side effects.\u00a0<\/span><\/p>\n<h2 id=\"buspirone-interactions-that-increase-the-risk-of-side-effects\"><span style=\"font-weight: 400;\">Buspirone interactions that increase the risk of side effects<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Although most people taking buspirone will be spared unpleasant side effects, drug interactions can increase the likelihood of developing minor or serious adverse reactions.\u00a0<\/span><\/p>\n<h3 id=\"monoamine-oxidase-inhibitors\"><span style=\"font-weight: 400;\">Monoamine oxidase inhibitors<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Because of the risk of high blood pressure and serotonin syndrome, buspirone should never be taken with <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/maois\/\"><span style=\"font-weight: 400;\">monoamine oxidase inhibitors (MAOIs)<\/span><\/a><span style=\"font-weight: 400;\">\u2014a small class of medications that includes the antidepressants Marplan (isocarboxazid), Nardil (phenelzine), Parnate (tranylcypromine), and Eldepryl (selegiline). It also includes the cancer drug procarbazine, the antibiotic linezolid, and methylene blue injections.<\/span><\/p>\n<h3 id=\"serotonergic-drugs\"><span style=\"font-weight: 400;\">Serotonergic drugs<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Buspirone increases serotonin levels in the brain. Serotonin is a neurotransmitter that passes signals between nerves. Serotonin syndrome, a potentially hazardous complication of drugs like buspirone, is more likely to occur when buspirone is combined with other drugs that raise serotonin levels (serotonergic drugs) or mimic serotonin (serotonin receptor agonists). These include the following medications:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Other anti-anxiety medications<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">SSRIs\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">SNRIs<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/drug-classes\/tricyclic-antidepressants\"><span style=\"font-weight: 400;\">Tricyclic antidepressants<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/drug-classes\/antipsychotics\"><span style=\"font-weight: 400;\">Antipsychotics<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Bipolar disorder medications, such as lithium<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Amphetamines<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/migraine-treatment-and-medications\"><span style=\"font-weight: 400;\">Migraine drugs<\/span><\/a><span style=\"font-weight: 400;\"> called <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/triptans\"><span style=\"font-weight: 400;\">triptans<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/blog\/anticonvulsants\/\"><span style=\"font-weight: 400;\">Seizure medications<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/blog\/opioids\/\"><span style=\"font-weight: 400;\">Opioids<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/blog\/antiemetics\/\"><span style=\"font-weight: 400;\">Anti-nausea medications<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Parkinson\u2019s disease medications<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Over-the-counter (OTC) dietary supplements, such as tryptophan and St. John\u2019s wort<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Other drugs can interfere with the body\u2019s ability to break down buspirone. Some drugs slow the process down, increasing the risk of buspirone\u2019s side effects. These include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/drug-classes\/macrolides\"><span style=\"font-weight: 400;\">Macrolide antibiotics<\/span><\/a><span style=\"font-weight: 400;\">, such as erythromycin<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Azole <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/antifungals\"><span style=\"font-weight: 400;\">antifungals<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Some antiviral drugs<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Migraine drugs called ergots<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Grapefruit and grapefruit juice<\/span><\/li>\n<\/ul>\n<h2 id=\"safety-measures-while-using-buspirone\"><span style=\"font-weight: 400;\">Safety measures while using buspirone<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Although buspirone is relatively safe, there are some safety measures to be aware of.<\/span><\/p>\n<h3 id=\"who-should-never-take-buspirone\"><span style=\"font-weight: 400;\">Who should never take buspirone?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Some people can\u2019t take buspirone safely because of medical conditions or other drugs that they\u2019re taking. These include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">People who have had an allergic reaction to buspirone<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">People taking MAOIs, serotonergic drugs, and drugs that interfere with the body\u2019s ability to break down buspirone<\/span><\/li>\n<\/ul>\n<h3 id=\"who-should-use-caution-when-taking-buspirone\"><span style=\"font-weight: 400;\">Who should use caution when taking buspirone?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Kidney or liver problems can raise buspirone levels in the blood, increasing the risk of potential side effects. Healthcare providers may prescribe a low dose of buspirone to compensate for this.<\/span><\/p>\n<h3 id=\"can-you-take-buspirone-when-pregnant-or-breastfeeding\"><span style=\"font-weight: 400;\">Can you take buspirone when pregnant or breastfeeding?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Yes. Healthcare providers prescribe buspirone to pregnant women because there\u2019s no evidence from human or animal studies that buspirone causes congenital disabilities or pregnancy problems. Still, you should tell your prescribing healthcare provider whether you are pregnant or plan to become pregnant while taking buspirone.\u00a0\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Women who are breastfeeding may also be prescribed buspirone. The drug crosses into human breast milk, but there have been no reports of adverse effects in nursing infants. However, the FDA cautions nursing women and their doctors to consider alternatives.\u00a0<\/span><\/p>\n<h3 id=\"does-buspirone-cause-withdrawal-symptoms\"><span style=\"font-weight: 400;\">Does buspirone cause withdrawal symptoms?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Buspirone should not be suddenly stopped because of the risk of <\/span><a href=\"https:\/\/www.mayoclinic.org\/drugs-supplements\/buspirone-oral-route\/description\/drg-20062457\"><span style=\"font-weight: 400;\">withdrawal side effects<\/span><\/a><span style=\"font-weight: 400;\">. While stopping it abruptly is not as dangerous as stopping a benzodiazepine, such as Xanax (alprazolam), it can still lead to unpleasant side effects, such as increased anxiety, dizziness, headache, irritability, nausea, nervousness, muscle cramps, trouble with sleeping, or fatigue. Talk to your health care provider before stopping buspirone or any other anti-anxiety medication. They can help you gradually reduce your dose safely with a buspirone taper schedule and avoid withdrawal side effects.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Like all drugs, it\u2019s possible to overdose on buspirone. Symptoms of an overdose include nausea, vomiting, drowsiness, dizziness, digestive system problems, and constricted pupils. There are no reports of death caused by a buspirone overdose. However, a buspirone overdose should be considered a medical emergency. Call <\/span><a href=\"https:\/\/triage.webpoisoncontrol.org\/#!\/exclusions\"><span style=\"font-weight: 400;\">Poison Control<\/span><\/a><span style=\"font-weight: 400;\"> at 800-222-1222 or call 911 if too much buspirone is taken.\u00a0<\/span><\/p>\n<h2 id=\"how-to-avoid-buspirone-side-effects\"><span style=\"font-weight: 400;\">How to avoid buspirone side effects<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Most people don\u2019t experience side effects when taking buspirone. When side effects do occur, they usually fade over time. Even so, a few precautions can help minimize possible side effects:<\/span><\/p>\n<ol>\n<li><b> Take buspirone as directed<\/b><span style=\"font-weight: 400;\">. <\/span><span style=\"font-weight: 400;\">Use an alarm or other reminder to take each dose at its scheduled time. If you miss a dose, take it as soon as you remember. If it\u2019s nearly time to take the next dose, skip the missed dose and take the next dose as scheduled. Never take extra medicine for any reason.<\/span><\/li>\n<li><b> Tell your healthcare provider about all of your medical conditions and medications<\/b><span style=\"font-weight: 400;\">. <\/span>The best way to prevent adverse effects and interactions is to give your prescribing healthcare provider a complete medical history and list of all medications that you\u2019re taking, including prescription drugs, OTC drugs, dietary supplements, and herbal products.<\/li>\n<li><b>Be careful about driving and other risky activities<\/b><span style=\"font-weight: 400;\">.<\/span> <span style=\"font-weight: 400;\">Although buspirone is not as strong of a sedative or muscle relaxant as other anti-anxiety medications, it can cause impairment. Avoid driving or working with heavy machinery until you know how the drug affects you.<\/span><\/li>\n<li><b> Avoid grapefruit and grapefruit juice<\/b><span style=\"font-weight: 400;\">.<\/span> <span style=\"font-weight: 400;\">Grapefruit has a chemical that slows down the body\u2019s ability to metabolize buspirone. One study found that people drinking grapefruit juice while taking buspirone had a total drug exposure that was <\/span><a href=\"https:\/\/ascpt.onlinelibrary.wiley.com\/doi\/abs\/10.1016\/S0009-9236%2898%2990056-X\"><span style=\"font-weight: 400;\">nine times the amount<\/span><\/a><span style=\"font-weight: 400;\"> of drug exposure in people who didn\u2019t drink grapefruit juice. That increased exposure to the drug comes with an increased risk of side effects.<\/span><\/li>\n<\/ol>\n<h2 id=\"how-to-treat-the-side-effects-of-buspirone\"><span style=\"font-weight: 400;\">How to treat the side effects of buspirone<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Talk to your prescribing healthcare provider if you experience concerning side effects of buspirone, such as dizziness or other types of impairment. Lowering the dose may help, and you can avoid risky or complex activities, such as driving a car or operating machinery.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Serious side effects are rare and may require immediate medical help. These include seizures and allergic reactions, which typically accompany symptoms like facial swelling.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If there are movement problems, such as involuntary grimacing, jerking, or others, immediately contact your prescribing healthcare provider.<\/span><\/p>\n<h2 id=\"bottom-line-is-buspirone-safe\"><span style=\"font-weight: 400;\">Bottom line: Is buspirone safe?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Compared to other anti-anxiety drugs, buspirone is considered one of the safest treatment options for generalized anxiety disorder and anxiety symptoms. Buspirone does not cause many side effects, but when it does, they\u2019re usually mild and temporary. There is no danger of drug dependence or addiction, and there\u2019s no known fatality due to a buspirone overdose. Always inform your prescribing healthcare provider of any other medications or supplements you regularly take so that they can determine whether buspirone is safe for your specific condition.<\/span><\/p>\n<h2 id=\"expert-takeaway\"><span style=\"font-weight: 400;\">Expert takeaway<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">\u201cBuspirone can be a safer alternative to other anti-anxiety medications,\u201d says Karen Berger, Pharm.D., member of the SingleCare Medical Board. \u201cThe right medication choice is different for everyone, so consulting with a healthcare provider can help determine the best treatment plan for you.\u201d<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Buspirone is a generic prescription drug that treats symptoms of anxiety disorders. Buspirone used to be sold under the brand name Buspar, which is no longer sold in the U.S. Although buspirone was originally developed as an antipsychotic, it was determined to be ineffective for psychosis. However, it works well as an anxiolytic (an anti-anxiety [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":62351,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[9777,12752],"coauthors":[8861],"class_list":["post-62350","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-anxiety","tag-medication-side-effects","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Buspirone side effects and how to avoid them<\/title>\n<meta name=\"description\" content=\"Dizziness, nervousness, nausea, and headache are the most common buspirone side effects, but they subside as the body gets used to the drug.\" \/>\n<meta name=\"robots\" content=\"index, follow, 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