{"id":62377,"date":"2024-01-09T12:57:13","date_gmt":"2024-01-09T17:57:13","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=62377"},"modified":"2026-03-17T09:50:32","modified_gmt":"2026-03-17T13:50:32","slug":"dicyclomine-interactions","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/dicyclomine-interactions\/","title":{"rendered":"Dicyclomine interactions to avoid"},"content":{"rendered":"

Relief from the abdominal pain and cramping of <\/span>irritable bowel syndrome<\/span><\/a> (IBS) can come in the form of <\/span>dicyclomine<\/span><\/a> tablets. The medication belongs to the anticholinergics class, but more specifically, it functions as an antispasmodic in IBS, relaxing smooth muscle spasms of the intestinal tract. As appealing as that sounds for sufferers of IBS pain, the drug\u2019s anticholinergic side effects, like dry mouth, dry skin, constipation, drowsiness, and blurred vision, are not the only cautionary tales to be aware of. Dicyclomine, also known by the brand name <\/span>Bentyl<\/span><\/a>, interacts with other anticholinergic treatments, which come from a range of different areas of healthcare. Besides learning how to avoid additive anticholinergic side effects, it is important to understand dicyclomine\u2019s important interactions with certain diuretics, anticonvulsants, pain medication, dementia treatments, potassium supplements, and cannabinoids.<\/span><\/p>\n

Dicyclomine drug interactions<\/span><\/h2>\n

The majority of what you need to watch out for is medication side effects that dicyclomine can magnify. Reduction in the effectiveness of cholinesterase inhibitors is noteworthy, too.<\/span><\/p>\n

Inhaled muscarinic antagonists<\/span><\/h3>\n

Spasms of the smooth muscle around bronchial tubes can be the bane of <\/span>COPD<\/span><\/a> by producing wheezing, cough, and shortness of breath. This spasm is relieved by inhaled antispasmodic agents, such as <\/span>beta-agonists<\/span><\/a> and <\/span>muscarinic antagonists<\/span><\/a>. The latter class does so by an anticholinergic mechanism. Coupled with dicyclomine, anticholinergic side effects can accumulate, namely constipation, dry mouth, drowsiness, difficulty urinating, and blurred vision.<\/span><\/p>\n

Examples of muscarinic antagonists to avoid or speak to the prescriber about include:<\/span><\/p>\n