{"id":62383,"date":"2024-01-11T14:02:22","date_gmt":"2024-01-11T19:02:22","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=62383"},"modified":"2024-10-25T10:16:35","modified_gmt":"2024-10-25T14:16:35","slug":"sumatriptan-interactions","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/sumatriptan-interactions\/","title":{"rendered":"Sumatriptan interactions to avoid"},"content":{"rendered":"

Sumatriptan<\/span><\/a>, marketed under the brand name Imitrex, is a triptan approved by the Food and Drug Administration (FDA) for treating <\/span>migraines<\/span><\/a>, with or without <\/span>aura<\/span><\/a>. It works by attaching to serotonin receptors in the brain. This narrows blood vessels in the head and blocks the release of substances that cause inflammation. <\/span>Sumatriptan<\/span><\/a> is available in several forms, including a tablet, injection, nasal powder, and nasal spray. The sumatriptan <\/span>injection<\/span><\/a> can also be used to treat cluster <\/span>headaches<\/span><\/a>. <\/span><\/p>\n

Although it is an effective treatment option for migraines, sumatriptan can interact with several drugs. These interactions can result in serious adverse effects, such as high blood pressure. Read on for more drug information and to learn more about which drugs sumatriptan can interact with and how to minimize the risk of interactions. <\/span><\/p>\n

Related: <\/b>Sumatriptan dosage<\/b><\/a> <\/b>Sumatriptan side effects<\/b><\/a><\/p>\n

Sumatriptan drug interactions<\/span><\/h2>\n

Sumatriptan interacts with various medications, including drugs that increase serotonin levels and certain antidepressants. These interactions increase the risk of serious side effects. Read on to learn about some of the most common sumatriptan drug interactions.<\/span><\/p>\n

Medications that increase serotonin levels<\/span><\/h3>\n

Serotonin syndrome<\/span><\/a> is a rare but serious condition that occurs when serotonin levels reach high levels in the body. Serotonin syndrome may happen if you take more than one medication that increases serotonin levels, if you take too much of a medication that increases serotonin levels, or if the dose of a medication that increases serotonin levels is raised. Symptoms can come on very quickly, and in some cases, they may become severe. Examples of symptoms include high blood pressure, fever, confusion, agitation, stiff muscles, and anxiety. If you develop any symptoms of serotonin syndrome, get emergency medical help immediately. <\/span><\/p>\n

Sumatriptan increases serotonin levels. Therefore, taking it with other medicines that raise serotonin increases the risk of serotonin syndrome. Other types of prescription drugs that are known to increase serotonin in the body are <\/span>selective serotonin reuptake inhibitors (SSRIs)<\/span><\/a>, <\/span>serotonin and norepinephrine reuptake inhibitors (SNRIs)<\/span><\/a>, and <\/span>tricyclic antidepressants (TCAs)<\/span><\/a>. <\/span><\/p>\n

Specific examples of drugs that increase serotonin levels include: <\/span><\/p>\n