{"id":626635,"date":"2024-02-09T15:50:40","date_gmt":"2024-02-09T20:50:40","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=626635"},"modified":"2026-03-23T15:16:04","modified_gmt":"2026-03-23T19:16:04","slug":"repatha-alternatives","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/repatha-alternatives\/","title":{"rendered":"Repatha (evolocumab) alternatives: What can I take instead of Repatha?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> (evolocumab) is an injectable medication prescribed to lower LDL (\u201cbad\u201d) cholesterol, especially in people with familial hypercholesterolemia or established heart disease. It works by blocking a protein called PCSK9, allowing the liver to remove more LDL from the bloodstream. While it can be effective when other medications and lifestyle changes aren\u2019t enough, it may not be right for everyone due to <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/repatha-without-insurance\/\"><span style=\"font-weight: 400;\">costs<\/span><\/a><span style=\"font-weight: 400;\">, side effects, or a preference to avoid injections. Fortunately, several alternatives may also help manage <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/high-cholesterol-treatment-and-medications\"><span style=\"font-weight: 400;\">high cholesterol levels<\/span><\/a><span style=\"font-weight: 400;\"> and reduce cardiovascular risk.<\/span><\/p>\n<h2 id=\"what-can-i-take-instead-of-repatha\"><span style=\"font-weight: 400;\">What can I take instead of Repatha?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">If Repatha isn\u2019t the right fit, other medications are available to help lower LDL cholesterol (LDL-C) and reduce heart disease risk. These include oral options like <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/statins\"><span style=\"font-weight: 400;\">statins<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/bile-acid-sequestrants\"><span style=\"font-weight: 400;\">bile acid sequestrants<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/fibrates\"><span style=\"font-weight: 400;\">fibrates<\/span><\/a><span style=\"font-weight: 400;\">, and <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/fatty-acids\"><span style=\"font-weight: 400;\">omega-3 fatty acids<\/span><\/a><span style=\"font-weight: 400;\">. Injectable options include Evkeeza (evinacumab-dgnb) and other PCSK9 inhibitors like Praluent (alirocumab) and Levqio (inclisiran). A newer drug like Nexletol (bempedoic acid) is also a potential alternative. Each option differs in how it works, how it&#8217;s taken, and its potential side effects, so it&#8217;s important to seek medical advice from your healthcare provider for the best option.\u00a0<\/span><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h3 id=\"compare-repatha-alternatives\">Compare Repatha alternatives<\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><b>Drug name<\/b><\/td>\n<td><b>Price without insurance<\/b><\/td>\n<td><b>SingleCare price<\/b><\/td>\n<td><b>Savings options<\/b><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Repatha (evolocumab)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$817 for 2, 1 mL of 140 mg\/mL syringes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$473 for 2, 1 mL of 140 mg\/mL syringes at Kroger or Harris Teeter<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/repatha\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Praluent (alirocumab)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$774 for 2, 1 mL of 75 mg\/mL pens<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$527 for 2, 1 mL of 75 mg\/mL pens at Kroger or Harris Teeter<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/praluent\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Leqvio (inclisiran)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$4,724 for 1, 1.5 mL of 284 mg\/1.5 mL pen<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$3,651 for 1, 1.5 mL of 284 mg\/1.5 mL pen at Kroger or Harris Teeter<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/leqvio\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Lipitor (atorvastatin)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$679 for 30, 40 mg tablets<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$8 for 30, 40 mg tablets at Kroger or Harris Teeter<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/lipitor\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Crestor (rosuvastatin)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$361 for 30, 10 mg tablets<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$8 for 30, 10 mg tablets at Kroger or Harris Teeter<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/crestor\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Zocor (simvastatin)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$1,028 for 90, 20 mg tablets<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$7 for 90, 20 mg tablets at Kroger or Harris Teeter<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/zocor\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Colestid (colestipol)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$180 for 60, 1 gm tablets<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$35 for 60, 1 gm tablets at CVS<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/colestid\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Welchol (colesevelam)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$1,008 for 180, 625 mg tablets<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$44 for 180, 625 mg tablets at CVS<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/welchol\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Niaspan (niacin)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$9 for 90, 500 mg tablets<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$5 for 90, 500 mg tablets at Walgreens<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/niacin\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Lovaza (omega-3-acid ethyl esters)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$1,492 per 120, 1 gm capsules<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$30 per 120, 1 gm capsules at Walgreens<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/lovaza\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Nexletol (bempedoic acid)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$595 for 30, 180 mg tablets<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$390 for 30, 180 mg tablets at Kroger or Harris Teeter<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/nexletol\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Zetia (ezetimibe)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$851 for 90, 10 mg tablets<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$14 for 90, 10 mg tablets at Kroger or Harris Teeter<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/ezetimibe\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Tricor (fenofibrate)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$216 for 90, 160 mg tablets<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$17 for 90, 160 mg tablets at Kroger or Harris Teeter<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/fenofibrate\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Evkeeza (evinacumab-dgnb)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$13,474 for 2.3 mL of 345 mg\/2.3 mL single-dose vial<\/span><\/td>\n<td><span style=\"font-weight: 400;\">N\/A<\/span><\/td>\n<td><span style=\"font-weight: 400;\">*Only available from your prescriber\u2019s office<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><small><i><span style=\"font-weight: 400;\">Prescription drug prices often change. These are the most accurate medication prices at the time of publishing in ZIP code 23666 as of March 23, 2026. The listed price without insurance references the price of brand-name drugs (unless otherwise specified). The listed SingleCare price references the price of generic drugs if available.<\/span><\/i><small><\/small><\/small><\/p>\n\t\t<div id=\"coupon-cta\" class=\"coupon-cta master-template\">\n\t\t\t<p id=\"headline\">Save up to 80% on Repatha with SingleCare<\/p>\n\t\t\t<p id=\"subheadline\">Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t<div class=\"details-wrap\">\n\t\t\t\t<div class=\"details\">\n\t\t\t\t\tRepatha 1ml of 140 mg\/mL (2 Injection)\t\t\t\t<\/div>\n\t\t\t\t<div class=\"address\">\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"api-response\">\n\t\t\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-kroger.svg\" alt=\"Kroger Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$504.51<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/repatha#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/repatha#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-harristeeter.svg\" alt=\"Harris Teeter Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$504.51<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/repatha#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/repatha#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/repatha#blog-cta\" class=\"coupon-see-all-btn\">See Repatha prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n<h3 id=\"other-alternatives-to-repatha\"><span style=\"font-weight: 400;\">Other alternatives to Repatha<\/span><\/h3>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Questran (cholestyramine)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lopid (gemfibrozil)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Trilipix (fenofibric acid)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fenoglide (fenofibrate)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Vascepa (icosapent ethyl)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Vytorin (ezetimibe\/ simvastatin)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mevacor (lovastatin)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Livalo (pitavastatin)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lescol (fluvastatin)<\/span><\/li>\n<\/ul>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/which-cholesterol-drug-is-safest\/\"><b>What\u2019s the safest cholesterol medication?<\/b><\/a><\/p>\n<h2 id=\"top-5-repatha-alternatives\"><span style=\"font-weight: 400;\">Top 5 Repatha alternatives<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The following are some of the most common alternatives to Repatha. Remember, all cholesterol-lowering therapies should be used in combination with lifestyle changes and an appropriate diet.<\/span><\/p>\n<h3 id=\"1-statin-medications\"><span style=\"font-weight: 400;\">1. Statin medications<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Statins are oral cholesterol-lowering medications often used as a first-line treatment for <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK430940\/\"><span style=\"font-weight: 400;\">high LDL cholesterol levels<\/span><\/a><span style=\"font-weight: 400;\">. Unlike Repatha, an injectable monoclonal antibody, statins are taken once daily by mouth and are available in many generic forms. They work by blocking an enzyme in the liver (HMG-CoA reductase) to <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/cholesterol-levels-by-age-chart\/\"><span style=\"font-weight: 400;\">reduce cholesterol production<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Statins are generally effective and affordable, but may cause <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/statin-side-effects\/\"><span style=\"font-weight: 400;\">muscle pain<\/span><\/a><span style=\"font-weight: 400;\">, which can limit their use in some people. They can be used alone or in combination with other treatments, such as Repatha, when stronger cholesterol control is required. Examples include Lipitor (atorvastatin), Crestor (rosuvastatin), and Zocor (simvastatin).<\/span><\/p>\n<h3 id=\"2-zetia-ezetimibe\"><span style=\"font-weight: 400;\">2. Zetia (ezetimibe)<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Zetia<\/span><span style=\"font-weight: 400;\"> contains ezetimibe, a cholesterol absorption inhibitor that can be combined with statins to lower LDL-C levels. Zetia is an oral, once-daily drug that works by blocking the absorption of cholesterol in the small intestine. Zetia can be effective in lowering LDL-C levels, with one study showing that Zetia lowered LDL cholesterol by about <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24691094\/\"><span style=\"font-weight: 400;\">17% to 19%<\/span><\/a><span style=\"font-weight: 400;\"> more than placebo.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The most common <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/ezetimibe-side-effects\/\"><span style=\"font-weight: 400;\">side effects<\/span><\/a><span style=\"font-weight: 400;\"> of Zetia are upper respiratory infection, diarrhea, and joint pain. People with severe liver disease should avoid using Zetia because their bodies may not process the drug properly, leading to higher levels and an increased risk of side effects.<\/span><\/p>\n<h3 id=\"3-nexletol-bempedoic-acid\"><span style=\"font-weight: 400;\">3. Nexletol (bempedoic acid)<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Nexletol<\/span><span style=\"font-weight: 400;\"> contains bempedoic acid, an ACL inhibitor that lowers LDL cholesterol by blocking cholesterol synthesis in the liver. Nexletol is an oral tablet taken once daily and is only approved for use in adults. Nexletol is intended to be used alongside statin therapy.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Clinical trials have shown that bempedoic acid can lower LDL cholesterol by <\/span><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10900064\"><span style=\"font-weight: 400;\">about 18%<\/span><\/a><span style=\"font-weight: 400;\"> when taken with a statin, 21% in people who are unable to take statins, and up to 38% when combined with ezetimibe. Side effects may include increased uric acid levels, elevated liver enzymes, muscle spasms, and back pain. There is no generic for Nexletol, and the average retail price is over $500 per month without insurance.<\/span><\/p>\n<h3 id=\"4-evkeeza-evinacumab-dgnb\"><span style=\"font-weight: 400;\">4. Evkeeza (evinacumab-dgnb)<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Evkeeza (evinacumab-dgnb) is a monthly injection used alongside other treatments to lower LDL cholesterol in people with familial hypercholesterolemia, including adults and children 5 and older. Like Repatha, it\u2019s a <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/monoclonal-antibodies\"><span style=\"font-weight: 400;\">monoclonal antibody<\/span><\/a><span style=\"font-weight: 400;\">, but it works by blocking enzymes involved in lipid metabolism. Evkeeza can also lower triglyceride levels, offering broader lipid control.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">This product is an injection that is only given <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2023\/761181s001lbl.pdf\"><span style=\"font-weight: 400;\">once per month<\/span><\/a><span style=\"font-weight: 400;\">. The most common side effects are flu-like symptoms, dizziness, and runny nose. Evkeeza does not currently have a generic on the market. Evkeeza can only be administered in a provider\u2019s office and be billed by them. This can not be purchased directly at the pharmacy for self-administration.<\/span><\/p>\n<h3 id=\"5-other-pcsk9-inhibitors\"><span style=\"font-weight: 400;\">5. Other PCSK9 inhibitors<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Other injectable PCSK9 inhibitors include Praluent (alirocumab) and Leqvio (inclisiran), both used to help lower LDL cholesterol in people with cardiovascular disease or genetic high cholesterol. <\/span><span style=\"font-weight: 400;\">Like Repatha, Praluent is a monoclonal antibody administered<\/span><a href=\"https:\/\/www.singlecare.com\/blog\/praluent-vs-repatha\/\"> <span style=\"font-weight: 400;\">every two to four weeks<\/span><\/a><span style=\"font-weight: 400;\">, whereas Leqvio is only administered<\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2024\/214012s011lbl.pdf\"> <span style=\"font-weight: 400;\">twice a year<\/span><\/a><span style=\"font-weight: 400;\">, following the initial two doses.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Common side effects include injection site reactions, flu-like symptoms, and muscle pain. Like Repatha, these drugs may also raise blood sugar levels. Both options require a prescription and are typically used alongside diet and other cholesterol-lowering therapies.<\/span><\/p>\n<h2 id=\"natural-alternatives-to-repatha\"><span style=\"font-weight: 400;\">Natural alternatives to Repatha<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">A heart-healthy, <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/low-cholesterol-diet\/\"><span style=\"font-weight: 400;\">low-cholesterol diet<\/span><\/a><span style=\"font-weight: 400;\"> is an important part of any cholesterol-lowering plan, whether or not you use medication. Focus on lean proteins, such as chicken, turkey, and fish, instead of processed meats like bologna or sausage. Choose fresh vegetables and season them with herbs and spices rather than heavy, oily sauces. You can also opt for low-fat or non-fat dairy products, and make sure to include plenty of fiber-rich foods like whole grains, fruits, beans, and vegetables.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Several natural products and supplements may help lower cholesterol, although they should not be used without medical advice.<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Red yeast rice contains monacolin K, a compound that\u2019s chemically identical to the prescription drug lovastatin. However, in the U.S., the FDA <\/span><a href=\"https:\/\/www.nccih.nih.gov\/health\/red-yeast-rice\"><span style=\"font-weight: 400;\">prohibits the sale<\/span><\/a><span style=\"font-weight: 400;\"> of red yeast rice products with more than trace amounts of monacolin K, so their effectiveness may vary. Products with higher monacolin K levels have shown cholesterol-lowering benefits, but can also cause statin-like side effects such as muscle pain.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Psyllium, a soluble fiber, has been shown to <\/span><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10201678\/\"><span style=\"font-weight: 400;\">lower LDL cholesterol<\/span><\/a><span style=\"font-weight: 400;\"> and may help slow the development of atherosclerosis. It forms a gel in the gut that traps bile acids, which are then excreted in waste. To avoid constipation or blockage, it\u2019s important to take psyllium with plenty of fluids.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37300664\/\"><span style=\"font-weight: 400;\">Other supplements<\/span><\/a><span style=\"font-weight: 400;\"> that may offer modest cholesterol-lowering effects include soy, green tea, berberine, guggul, and garlic.\u00a0<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Always consult a healthcare provider before starting a natural product or supplement to lower cholesterol. They can help determine whether it\u2019s safe and effective for your condition.\u00a0<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/natural-remedies-for-high-cholesterol\/\"><b>10 natural remedies for high cholesterol<\/b><\/a><\/p>\n<h2 id=\"how-to-switch-to-a-repatha-alternative\"><span style=\"font-weight: 400;\">How to switch to a Repatha alternative<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">There may be various reasons you are considering a change from Repatha. Whether it is due to cost, side effects, method of administration, or allergic sensitivities, there are other cholesterol-lowering medications besides Repatha. The first step is to speak to your healthcare provider.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">It is important to have your cholesterol checked regularly with blood draws and lab work. The results of those tests can help you and your doctor make an appropriate choice. Other comorbidities, such as diabetes or high blood pressure, may also affect which medication to take.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Your pharmacist or insurance plan can provide more information on your <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/what-is-a-formulary\/\"><span style=\"font-weight: 400;\">formulary<\/span><\/a><span style=\"font-weight: 400;\"> coverage and what options would be most cost-effective with your plan. If you don\u2019t have insurance coverage or want to ensure you are paying the best price, check SingleCare to find the best prices at pharmacies near you.<\/span><\/p>\n<h2 id=\"choosing-the-right-path-for-high-cholesterol-treatment\"><span style=\"font-weight: 400;\">Choosing the right path for high cholesterol treatment<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">There are many alternatives to Repatha, including statins, other oral drugs, injectable medications, and even natural supplements. Each option works differently and has its own pros and cons. The best option will depend on your reason for switching from Repatha. Talk to your healthcare provider to find the right treatment plan based on your cholesterol levels, health history, and budget.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Repatha (evolocumab) is an injectable medication prescribed to lower LDL (\u201cbad\u201d) cholesterol, especially in people with familial hypercholesterolemia or established heart disease. It works by blocking a protein called PCSK9, allowing the liver to remove more LDL from the bloodstream. While it can be effective when other medications and lifestyle changes aren\u2019t enough, it may [&hellip;]<\/p>\n","protected":false},"author":133,"featured_media":626636,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[737],"coauthors":[10437],"class_list":["post-626635","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-heart-health","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Top Repatha (evolocumab) alternatives and how to switch your Rx<\/title>\n<meta name=\"description\" content=\"ANGPTL3, bile acid sequestrants, Nexletol, statins, and Zetia are some Repatha alternatives. 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