{"id":626768,"date":"2024-02-20T08:59:58","date_gmt":"2024-02-20T13:59:58","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=626768"},"modified":"2024-10-25T10:08:03","modified_gmt":"2024-10-25T14:08:03","slug":"mirtazapine-interactions","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/mirtazapine-interactions\/","title":{"rendered":"Mirtazapine interactions to avoid"},"content":{"rendered":"<p><a href=\"https:\/\/www.singlecare.com\/prescription\/mirtazapine\"><span style=\"font-weight: 400;\">Mirtazapine<\/span><\/a><span style=\"font-weight: 400;\"> is a member of a drug class called tetracyclic antidepressants. Mirtazapine is approved by the U.S. Food and Drug Administration (<\/span><span style=\"font-weight: 400;\">) to treat <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/depression-treatment-and-medications\"><span style=\"font-weight: 400;\">depression<\/span><\/a><span style=\"font-weight: 400;\">, also known as major depressive disorder or major depression, in adults. It works by increasing levels of serotonin and norepinephrine in the brain. Serotonin and norepinephrine are neurotransmitters (chemical messengers). They regulate various functions, like mood, sleep, memory, and others.&nbsp;<\/span><\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/mirtazapine\/what-is\"><span style=\"font-weight: 400;\">Mirtazapine<\/span><\/a><span style=\"font-weight: 400;\"> is a generic medication and is commonly known by the brand name <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/remeron\"><span style=\"font-weight: 400;\">Remeron<\/span><\/a><span style=\"font-weight: 400;\">. It is available in <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/mirtazapine\/dosage\"><span style=\"font-weight: 400;\">several formulations<\/span><\/a><span style=\"font-weight: 400;\">, including oral tablets (Remeron) and orally disintegrating tablets (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/remeron-soltab\"><span style=\"font-weight: 400;\">Remeron Soltab<\/span><\/a><span style=\"font-weight: 400;\">).<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Some of the most <\/span><a href=\"https:\/\/medlineplus.gov\/druginfo\/meds\/a697009.html\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">common side effects<\/span><\/a><span style=\"font-weight: 400;\"> of mirtazapine include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stomach problems like nausea, vomiting, and constipation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness and drowsiness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Anxiety<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Confusion<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Increased appetite<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Weight gain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dry mouth<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Increased <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/high-cholesterol-treatment-and-medications\"><span style=\"font-weight: 400;\">cholesterol<\/span><\/a><span style=\"font-weight: 400;\"> and triglycerides<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Mirtazapine interacts with various drugs, including monoamine oxidase inhibitors (MAOIs) and other drugs that increase serotonin levels, benzodiazepines, and others. For those who take mirtazapine, it&rsquo;s important to be aware of possible interactions that can affect the effectiveness of this medication or cause other potential complications.<\/span><\/p>\n<h2 id=\"mirtazapine-drug-interactions\"><span style=\"font-weight: 400;\">Mirtazapine drug interactions<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Mirtazapine interacts with various drugs and classes of drugs, which can result in different complications.<\/span><\/p>\n<h3 id=\"monoamine-oxidase-inhibitors-maois\"><span style=\"font-weight: 400;\">Monoamine oxidase inhibitors (MAOIs)<\/span><\/h3>\n<p><a href=\"https:\/\/www.singlecare.com\/drug-classes\/maois\"><span style=\"font-weight: 400;\">Monoamine oxidase inhibitors<\/span><\/a><span style=\"font-weight: 400;\"> (MAOIs) are a class of drugs used to treat depression and other <\/span><span style=\"font-weight: 400;\">neurologic conditions such as <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/parkinsons-symptoms\"><span style=\"font-weight: 400;\">Parkinson&rsquo;s disease<\/span><\/a><span style=\"font-weight: 400;\"> and <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/news\/alzheimers-statistics\/\"><span style=\"font-weight: 400;\">Alzheimer&rsquo;s disease<\/span><\/a><span style=\"font-weight: 400;\">.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">An MAOI drug should never be taken with mirtazapine or within 14 days of taking mirtazapine. Combining an MAOI with mirtazapine could result in a life-threatening condition called <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/serotonin-syndrome-treatment-and-medications\"><span style=\"font-weight: 400;\">serotonin syndrome<\/span><\/a><span style=\"font-weight: 400;\">, which occurs due to the buildup of too much serotonin.&nbsp;&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Serotonin syndrome symptoms can range from mild to life-threatening and can even cause death if untreated. Symptoms of serotonin syndrome may include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Changes in mental status, such as agitation, delirium, and hallucinations<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fast heartbeat<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Changes in <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/blood-pressure-levels\/\"><span style=\"font-weight: 400;\">blood pressure<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sweating, flushing, high fever<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Shaking<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stiff muscles<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Incoordination<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Seizures<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stomach symptoms like nausea, vomiting, and diarrhea<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">If you take an MAOI, your healthcare provider will not prescribe mirtazapine. Examples of MAOIs include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/azilect\"><span style=\"font-weight: 400;\">Azilect<\/span><\/a><span style=\"font-weight: 400;\"> (rasagiline)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/marplan\/what-is\"><span style=\"font-weight: 400;\">Marplan<\/span><\/a><span style=\"font-weight: 400;\"> (isocarboxazid)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/methylene-blue\/what-is\"><span style=\"font-weight: 400;\">Methylene blue<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/nardil\"><span style=\"font-weight: 400;\">Nardil<\/span><\/a><span style=\"font-weight: 400;\"> (phenelzine)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/parnate\"><span style=\"font-weight: 400;\">Parnate<\/span><\/a><span style=\"font-weight: 400;\"> (tranylcypromine)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/selegiline-hcl\/what-is\"><span style=\"font-weight: 400;\">Selegiline<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/zyvox\"><span style=\"font-weight: 400;\">Zyvox<\/span><\/a><span style=\"font-weight: 400;\"> (linezolid)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Serotonin syndrome does not always involve a drug interaction. It can occur with just one drug, including mirtazapine alone. If you take mirtazapine, your healthcare provider will monitor you for serotonin syndrome.&nbsp;<\/span><\/p>\n<h3 id=\"other-drugs-that-increase-the-risk-of-serotonin-syndrome\"><span style=\"font-weight: 400;\">Other drugs that increase the risk of serotonin syndrome<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">In addition to MAOIs, other drugs may increase the risk of serotonin syndrome when used in combination with mirtazapine. However, the difference is that, with these other medications, a two-week period is not required between using mirtazapine and using another medication that affects serotonin levels (called serotonergic drugs).<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Healthcare providers try to avoid combining two drugs that increase serotonin levels. However, in some cases, another alternative is not available, and two serotonergic drugs are prescribed together. In these cases, the patient will be closely monitored for <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/serotonin-syndrome-symptoms\/\"><span style=\"font-weight: 400;\">symptoms of serotonin syndrome<\/span><\/a><span style=\"font-weight: 400;\">. People with symptoms of serotonin syndrome should get emergency medical help.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Examples of drugs that increase the risk of serotonin syndrome include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/blog\/news\/ssri-weight-gain-statistics\/\"><span style=\"font-weight: 400;\">SSRI antidepressants<\/span><\/a><span style=\"font-weight: 400;\"> such as Celexa (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/celexa\/dosage\"><span style=\"font-weight: 400;\">citalopram<\/span><\/a><span style=\"font-weight: 400;\">), <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/paxil\/what-is\"><span style=\"font-weight: 400;\">Paxil<\/span><\/a><span style=\"font-weight: 400;\"> (paroxetine), <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/prozac-generic\/\"><span style=\"font-weight: 400;\">Prozac<\/span><\/a><span style=\"font-weight: 400;\"> (fluoxetine), or <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/lexapro-vs-zoloft\/\"><span style=\"font-weight: 400;\">Lexapro<\/span><\/a><span style=\"font-weight: 400;\"> (escitalopram)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/blog\/ssris-vs-snris\/\"><span style=\"font-weight: 400;\">SNRI antidepressants<\/span><\/a><span style=\"font-weight: 400;\"> such as <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/cymbalta-for-anxiety\/\"><span style=\"font-weight: 400;\">Cymbalta<\/span><\/a><span style=\"font-weight: 400;\"> (duloxetine) or <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/effexor-vs-wellbutrin\/\"><span style=\"font-weight: 400;\">Effexor<\/span><\/a><span style=\"font-weight: 400;\"> (venlafaxine)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/blog\/tricyclic-antidepressants\/\"><span style=\"font-weight: 400;\">Tricyclic antidepressants<\/span><\/a><span style=\"font-weight: 400;\"> such as Elavil (<\/span><a href=\"https:\/\/www.singlecare.com\/blog\/amitriptyline-for-sleep\/\"><span style=\"font-weight: 400;\">amitriptyline<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/drug-classes\/triptans\"><span style=\"font-weight: 400;\">Triptans<\/span><\/a><span style=\"font-weight: 400;\"> for <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/migraine-types\/\"><span style=\"font-weight: 400;\">migraine<\/span><\/a><span style=\"font-weight: 400;\"> such as Imitrex (<\/span><a href=\"https:\/\/www.singlecare.com\/blog\/sumatriptan-side-effects\/\"><span style=\"font-weight: 400;\">sumatriptan<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/blog\/lithium-side-effects\/\"><span style=\"font-weight: 400;\">Lithium<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Amphetamines such as <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/adderall-generic\/\"><span style=\"font-weight: 400;\">Adderall<\/span><\/a><span style=\"font-weight: 400;\"> (mixed amphetamine salts)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/blog\/news\/opioid-epidemic-statistics-legislation\/\"><span style=\"font-weight: 400;\">Opioid pain medications<\/span><\/a><span style=\"font-weight: 400;\"> such as <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/fentanyl-side-effects\/\"><span style=\"font-weight: 400;\">fentanyl<\/span><\/a><span style=\"font-weight: 400;\"> or Ultram (<\/span><a href=\"https:\/\/www.singlecare.com\/blog\/tramadol-alternatives\/\"><span style=\"font-weight: 400;\">tramadol<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/blog\/buspirone-without-insurance\/\"><span style=\"font-weight: 400;\">Buspirone<\/span><\/a><span style=\"font-weight: 400;\">&nbsp;<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dietary supplements such as St. John&rsquo;s wort, tryptophan, and SAMe<\/span><\/li>\n<\/ul>\n<h3 id=\"drugs-that-affect-an-enzyme-called-cyp3a4\"><span style=\"font-weight: 400;\">Drugs that affect an enzyme called CYP3A4<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Cytochrome P450 3A4 is an enzyme involved in the processing of many medications. Certain drugs can affect this enzyme.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">For example, strong CYP3A inducers speed up the processing of mirtazapine in the body. This means your body eliminates it faster, so a regular dose may not be as effective. If you take mirtazapine with a strong CYP3A inducer, you may need a higher dose of mirtazapine. Examples of strong CYP3A inducers include <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/dilantin\"><span style=\"font-weight: 400;\">Dilantin<\/span><\/a><span style=\"font-weight: 400;\"> (phenytoin), Tegretol (<\/span><a href=\"https:\/\/www.singlecare.com\/blog\/carbamazepine-side-effects\/\"><span style=\"font-weight: 400;\">carbamazepine<\/span><\/a><span style=\"font-weight: 400;\">), and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/rifampin\"><span style=\"font-weight: 400;\">rifampin<\/span><\/a><span style=\"font-weight: 400;\">.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">On the other hand, strong CYP3A inhibitors slow down the processing of mirtazapine in the body. This could lead to higher levels of mirtazapine in the body and worsening of adverse effects. If you take mirtazapine with a strong CYP3A inhibitor, you may need a lower dose of mirtazapine. Examples of strong CYP3A inhibitors include <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/itraconazole\"><span style=\"font-weight: 400;\">itraconazole<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/ketoconazole\"><span style=\"font-weight: 400;\">ketoconazole<\/span><\/a><span style=\"font-weight: 400;\">, and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/ritonavir\/what-is\"><span style=\"font-weight: 400;\">ritonavir<\/span><\/a><span style=\"font-weight: 400;\">.&nbsp;<\/span><\/p>\n<h3 id=\"benzodiazepines\"><span style=\"font-weight: 400;\">Benzodiazepines<\/span><\/h3>\n<p><a href=\"https:\/\/www.singlecare.com\/drug-classes\/benzodiazepines\"><span style=\"font-weight: 400;\">Benzodiazepines<\/span><\/a><span style=\"font-weight: 400;\"> are a class of medications used for <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/anxiety-vs-depression\/\"><span style=\"font-weight: 400;\">anxiety<\/span><\/a><span style=\"font-weight: 400;\">. Some benzodiazepines have other uses as well, such as to treat muscle spasms or <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/epilepsy-treatment-and-medications\"><span style=\"font-weight: 400;\">seizures<\/span><\/a><span style=\"font-weight: 400;\">. Mirtazapine causes central nervous system (CNS) depression, which means a slowing down of the nervous system. Benzodiazepines have the same effect, so combining mirtazapine with a benzodiazepine could result in additive effects. In severe cases, excess CNS depression can cause slowed breathing, loss of consciousness, coma, and death. Also, both mirtazapine and benzodiazepines cause sedation, so combining them can increase this sedative effect. The prescribing information states that mirtazapine and benzodiazepines should not be combined.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Examples of benzodiazepines include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/blog\/ativan-alternatives\/\"><span style=\"font-weight: 400;\">Ativan<\/span><\/a><span style=\"font-weight: 400;\"> (lorazepam)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/blog\/klonopin-vs-ativan\/\"><span style=\"font-weight: 400;\">Klonopin<\/span><\/a><span style=\"font-weight: 400;\"> (clonazepam)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/valium\"><span style=\"font-weight: 400;\">Valium<\/span><\/a><span style=\"font-weight: 400;\"> (diazepam)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/blog\/how-long-does-xanax-last\/\"><span style=\"font-weight: 400;\">Xanax<\/span><\/a><span style=\"font-weight: 400;\"> (alprazolam)<\/span><\/li>\n<\/ul>\n<h3 id=\"drugs-that-prolong-the-qt-interval\"><span style=\"font-weight: 400;\">Drugs that prolong the QT interval<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">When you get an electrocardiogram (EKG), there is a measurement called the QT interval. A prolonged QT interval could result in an arrhythmia (irregular heart rhythm), which could be dangerous or cause death. In rare cases, mirtazapine can cause a QT prolongation. Mirtazapine should be used with caution in individuals who have (or are at risk for) a prolonged QT interval. Mirtazapine should not be used with certain drugs due to an increased risk of causing a prolonged QT interval. Examples of interacting drugs include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/blog\/amiodarone-alternatives\/\"><span style=\"font-weight: 400;\">Amiodarone<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/drug-classes\/antipsychotics\"><span style=\"font-weight: 400;\">Antipsychotics<\/span><\/a><span style=\"font-weight: 400;\"> such as <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/geodon\/what-is\"><span style=\"font-weight: 400;\">Geodon (ziprasidone)<\/span><\/a><span style=\"font-weight: 400;\"> or <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/haloperidol\"><span style=\"font-weight: 400;\">haloperidol<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/blog\/multaq-without-insurance\/\"><span style=\"font-weight: 400;\">Dronedarone<\/span><\/a><span style=\"font-weight: 400;\">&nbsp;<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Macrolide antibiotics such as <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/erythromycin\"><span style=\"font-weight: 400;\">erythromycin<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/clarithromycin\/what-is\"><span style=\"font-weight: 400;\">Biaxin (clarithromycin)<\/span><\/a><span style=\"font-weight: 400;\">, or <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/what-is-a-z-pak\/\"><span style=\"font-weight: 400;\">Zithromax (azithromycin)<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/procainamide-hcl\"><span style=\"font-weight: 400;\">Procainamide<\/span><\/a><span style=\"font-weight: 400;\">&nbsp;<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Quinidine<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sotalol<\/span><\/li>\n<\/ul>\n<h3 id=\"warfarin\"><span style=\"font-weight: 400;\">Warfarin<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">People who take the <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/new-blood-thinners\/\"><span style=\"font-weight: 400;\">blood thinner<\/span><\/a><span style=\"font-weight: 400;\"> warfarin with mirtazapine will require close monitoring. The combination could potentially increase the INR, which means that the blood takes longer to clot&mdash;leading to a higher risk of bleeding. Be sure to tell your doctor if you take <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/eliquis-vs-warfarin\/\"><span style=\"font-weight: 400;\">warfarin<\/span><\/a><span style=\"font-weight: 400;\"> before taking mirtazapine so that you can be appropriately monitored. This interaction does not apply to newer blood thinners such as <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/eliquis-vs-xarelto\/\"><span style=\"font-weight: 400;\">Xarelto or Eliquis<\/span><\/a><span style=\"font-weight: 400;\">.&nbsp;<\/span><\/p>\n<h3 id=\"tagamet-cimetidine\"><span style=\"font-weight: 400;\">Tagamet (cimetidine)<\/span><\/h3>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/tagamet-hb\"><span style=\"font-weight: 400;\">Tagamet<\/span><\/a><span style=\"font-weight: 400;\"> (cimetidine) is a medication used to treat conditions such as <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/best-heartburn-medicine\/\"><span style=\"font-weight: 400;\">heartburn<\/span><\/a><span style=\"font-weight: 400;\"> and ulcers. Combining Tagamet with mirtazapine can lead to an interaction that causes increased levels of mirtazapine in the body. This can lead to more serious mirtazapine side effects. If you take Tagamet, your healthcare professional may recommend switching to a different stomach medication while taking mirtazapine. Or, if that is not possible, your healthcare provider may recommend that you take a lower dose of mirtazapine while you are also taking Tagamet.<\/span><\/p>\n<h2 id=\"other-mirtazapine-contraindications-and-interactions\"><span style=\"font-weight: 400;\">Other mirtazapine contraindications and interactions<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Mirtazapine has some contraindications to be aware of, and it also has interactions with alcohol, CBD, and marijuana.<\/span><\/p>\n<h3 id=\"mirtazapine-contraindications\"><span style=\"font-weight: 400;\">Mirtazapine contraindications<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Mirtazapine is not safe for everyone to take. <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK519059\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Contraindications<\/span><\/a><span style=\"font-weight: 400;\"> of mirtazapine (situations where you should not take this medication) include people who:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Are allergic to mirtazapine or any ingredient in the medication<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Take an MAOI medication, or have taken an MAOI in the past 14 days. This includes the antibiotic <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/zyvox\/what-is\"><span style=\"font-weight: 400;\">Zyvox<\/span><\/a><span style=\"font-weight: 400;\"> (linezolid) and intravenous <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/methylene-blue\"><span style=\"font-weight: 400;\">methylene blue<\/span><\/a><span style=\"font-weight: 400;\"> (used to treat a condition called <\/span><span style=\"font-weight: 400;\">methemoglobinemia). Both of these medications<\/span><span style=\"font-weight: 400;\"> are also classified as MAOIs.&nbsp;<\/span><\/li>\n<\/ul>\n<h3 id=\"mirtazapine-and-alcohol\"><span style=\"font-weight: 400;\">Mirtazapine and alcohol&nbsp;<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">While taking mirtazapine, you should avoid alcohol. This interaction is similar to the benzodiazepine interaction described above. Both mirtazapine and alcohol cause CNS depression, so combining the two could result in additive effects. In severe cases, slowed breathing, loss of consciousness, coma, and death could even occur. Also, both mirtazapine and alcohol cause sedation, so combining the two can increase the sedative effect.<\/span><\/p>\n<h3 id=\"mirtazapine-and-cbd-marijuana\"><span style=\"font-weight: 400;\">Mirtazapine and CBD\/marijuana<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">If you use <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/news\/cbd-statistics\/\"><span style=\"font-weight: 400;\">CBD<\/span><\/a><span style=\"font-weight: 400;\"> or marijuana, check with your healthcare provider before using it with mirtazapine. CBD and marijuana both cause CNS depression and impairment, so combining either of these with mirtazapine can result in additive effects.&nbsp;<\/span><\/p>\n<h3 id=\"mirtazapine-and-certain-dietary-supplements\"><span style=\"font-weight: 400;\">Mirtazapine and certain dietary supplements<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Mirtazapine should not be combined with certain dietary supplements because of an interaction that can increase the risk for serotonin syndrome. These include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/blog\/st-johns-wort\/\"><span style=\"font-weight: 400;\">St. John&rsquo;s wort<\/span><\/a><span style=\"font-weight: 400;\"> (a dietary supplement used for mild depression)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tryptophan (a dietary supplement used for various conditions, including <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/insomnia-treatment-and-medications\"><span style=\"font-weight: 400;\">insomnia<\/span><\/a><span style=\"font-weight: 400;\"> and depression)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">SAMe (a dietary supplement used for various conditions, such as depression or <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/arthritis-treatment-and-medications\"><span style=\"font-weight: 400;\">osteoarthritis<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/li>\n<\/ul>\n<h2 id=\"how-to-minimize-mirtazapine-interactions\"><span style=\"font-weight: 400;\">How to minimize mirtazapine interactions<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Although mirtazapine has some potential interactions, in many cases, it can still be taken safely with some precautions.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Always consult your healthcare provider for medical advice before beginning a new medicine. Before you start taking mirtazapine, make your provider aware of all of your medical conditions, <\/span><a href=\"https:\/\/my.clevelandclinic.org\/health\/drugs\/18378-mirtazapine-tablets\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">especially if you<\/span><\/a><span style=\"font-weight: 400;\">:&nbsp;<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Are pregnant or trying to become pregnant<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Are breastfeeding&nbsp;<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Have <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/bipolar-disorder-treatment-and-medications\"><span style=\"font-weight: 400;\">bipolar disorder<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Have <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/glaucoma-treatment-and-medications\"><span style=\"font-weight: 400;\">glaucoma<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Have kidney disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Have liver disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Have (or have had) suicidal thoughts<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Have ever had a reaction to mirtazapine or any other allergies<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Before you take mirtazapine, tell your physician about all of the medicines you take, including prescription and OTC drugs, vitamins, supplements, or herbal products. While taking mirtazapine, do not start any new medicines unless approved by your healthcare provider.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Your healthcare provider may need to change your medicine or adjust the dose of mirtazapine&mdash;or another medicine&mdash;in the event of a potential drug interaction.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Always take your medication as directed by your healthcare provider. Do not take more medication than prescribed. If you have any questions or concerns, consult your healthcare provider.<\/span><\/p>\n<h2 id=\"when-to-talk-to-a-healthcare-provider-about-mirtazapine-interactions\"><span style=\"font-weight: 400;\">When to talk to a healthcare provider about mirtazapine interactions<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">This article outlines some common mirtazapine interactions but is not a complete list of every potential interaction. Tell your healthcare provider about all the medical conditions you have&mdash;as well as all of the medicines you take, including prescription and OTC medicines, vitamins, and supplements. Doing so helps ensure proper management and monitoring of your medical condition.&nbsp;<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Mirtazapine is a member of a drug class called tetracyclic antidepressants. Mirtazapine is approved by the U.S. Food and Drug Administration () to treat depression, also known as major depressive disorder or major depression, in adults. It works by increasing levels of serotonin and norepinephrine in the brain. Serotonin and norepinephrine are neurotransmitters (chemical messengers). [&hellip;]<\/p>\n","protected":false},"author":133,"featured_media":626780,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[451,814],"coauthors":[10668],"class_list":["post-626768","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-depression","tag-drug-interactions","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Mirtazapine interactions to avoid | SingleCare<\/title>\n<meta name=\"description\" content=\"Mirtazapine (Remeron) interacts with MAOIs, benzodiazepines, Warfarin, and alcohol, Here\u2019s what you should not take with mirtazapine to avoid side effects.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.singlecare.com\/blog\/mirtazapine-interactions\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Mirtazapine interactions to avoid\" \/>\n<meta property=\"og:description\" content=\"Mirtazapine (Remeron) interacts with MAOIs, benzodiazepines, Warfarin, and alcohol, Here\u2019s what you should not take with mirtazapine to avoid side effects.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.singlecare.com\/blog\/mirtazapine-interactions\/\" \/>\n<meta property=\"og:site_name\" content=\"The Checkup\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/singlecare\" \/>\n<meta property=\"article:published_time\" content=\"2024-02-20T13:59:58+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-10-25T14:08:03+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2024\/02\/mirtazapine-interactions.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"1080\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Karen Berger, Pharm.D.\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@SingleCare\" \/>\n<meta name=\"twitter:site\" content=\"@SingleCare\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Karen Berger, Pharm.D.\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"8 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/mirtazapine-interactions\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/mirtazapine-interactions\\\/\"},\"author\":{\"name\":\"Christie Falzone\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#\\\/schema\\\/person\\\/5ff7c7bb5ce0c66a6962ecf7c8d7941e\"},\"headline\":\"Mirtazapine interactions to avoid\",\"datePublished\":\"2024-02-20T13:59:58+00:00\",\"dateModified\":\"2024-10-25T14:08:03+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/mirtazapine-interactions\\\/\"},\"wordCount\":1647,\"publisher\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/mirtazapine-interactions\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2024\\\/02\\\/mirtazapine-interactions.png\",\"keywords\":[\"Depression\",\"Drug interactions\"],\"articleSection\":[\"Drug Info\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/mirtazapine-interactions\\\/\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/mirtazapine-interactions\\\/\",\"name\":\"Mirtazapine interactions to avoid | SingleCare\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/mirtazapine-interactions\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/mirtazapine-interactions\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2024\\\/02\\\/mirtazapine-interactions.png\",\"datePublished\":\"2024-02-20T13:59:58+00:00\",\"dateModified\":\"2024-10-25T14:08:03+00:00\",\"description\":\"Mirtazapine (Remeron) interacts with MAOIs, benzodiazepines, Warfarin, and alcohol, Here\u2019s what you should not take with mirtazapine to avoid side effects.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/mirtazapine-interactions\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/mirtazapine-interactions\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/mirtazapine-interactions\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2024\\\/02\\\/mirtazapine-interactions.png\",\"contentUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2024\\\/02\\\/mirtazapine-interactions.png\",\"width\":1920,\"height\":1080,\"caption\":\"Rx prescription pad with Rx pills: Mirtazapine interactions\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/mirtazapine-interactions\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Mirtazapine interactions to avoid\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#website\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/\",\"name\":\"The Checkup, a health blog by SingleCare\",\"description\":\"Read the latest in prescription, wellness, and healthcare news\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#organization\",\"name\":\"SingleCare\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2020\\\/01\\\/placeholderimage-1.jpg\",\"contentUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2020\\\/01\\\/placeholderimage-1.jpg\",\"width\":1200,\"height\":630,\"caption\":\"SingleCare\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/singlecare\",\"https:\\\/\\\/x.com\\\/SingleCare\",\"https:\\\/\\\/www.instagram.com\\\/singlecare\\\/?hl=en\",\"https:\\\/\\\/www.linkedin.com\\\/company\\\/singlecare\\\/\",\"https:\\\/\\\/www.youtube.com\\\/channel\\\/UCd9kiPIjCQw95-2BHCYePKA\"]},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#\\\/schema\\\/person\\\/5ff7c7bb5ce0c66a6962ecf7c8d7941e\",\"name\":\"Christie Falzone\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/2e99585820d49affcf442acba86e464b68d836bf071db26829d667da12209555?s=96&d=mm&r=gf47683752158743086d9c95bc1ebdaa7\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/2e99585820d49affcf442acba86e464b68d836bf071db26829d667da12209555?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/2e99585820d49affcf442acba86e464b68d836bf071db26829d667da12209555?s=96&d=mm&r=g\",\"caption\":\"Christie Falzone\"},\"description\":\"Christie Falzone recently graduated summa cum laude from Old Dominion University in Norfolk, Virginia, with a bachelor\u2019s degree in professional writing. During her time in college, she developed a passion for helping children and volunteers as a Court Appointed Special Advocate on behalf of foster youth.\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/author\\\/cfalzone\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Mirtazapine interactions to avoid | SingleCare","description":"Mirtazapine (Remeron) interacts with MAOIs, benzodiazepines, Warfarin, and alcohol, Here\u2019s what you should not take with mirtazapine to avoid side effects.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.singlecare.com\/blog\/mirtazapine-interactions\/","og_locale":"en_US","og_type":"article","og_title":"Mirtazapine interactions to avoid","og_description":"Mirtazapine (Remeron) interacts with MAOIs, benzodiazepines, Warfarin, and alcohol, Here\u2019s what you should not take with mirtazapine to avoid side effects.","og_url":"https:\/\/www.singlecare.com\/blog\/mirtazapine-interactions\/","og_site_name":"The Checkup","article_publisher":"https:\/\/www.facebook.com\/singlecare","article_published_time":"2024-02-20T13:59:58+00:00","article_modified_time":"2024-10-25T14:08:03+00:00","og_image":[{"width":1920,"height":1080,"url":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2024\/02\/mirtazapine-interactions.png","type":"image\/png"}],"author":"Karen Berger, Pharm.D.","twitter_card":"summary_large_image","twitter_creator":"@SingleCare","twitter_site":"@SingleCare","twitter_misc":{"Written by":"Karen Berger, Pharm.D.","Est. reading time":"8 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.singlecare.com\/blog\/mirtazapine-interactions\/#article","isPartOf":{"@id":"https:\/\/www.singlecare.com\/blog\/mirtazapine-interactions\/"},"author":{"name":"Christie Falzone","@id":"https:\/\/www.singlecare.com\/blog\/#\/schema\/person\/5ff7c7bb5ce0c66a6962ecf7c8d7941e"},"headline":"Mirtazapine interactions to avoid","datePublished":"2024-02-20T13:59:58+00:00","dateModified":"2024-10-25T14:08:03+00:00","mainEntityOfPage":{"@id":"https:\/\/www.singlecare.com\/blog\/mirtazapine-interactions\/"},"wordCount":1647,"publisher":{"@id":"https:\/\/www.singlecare.com\/blog\/#organization"},"image":{"@id":"https:\/\/www.singlecare.com\/blog\/mirtazapine-interactions\/#primaryimage"},"thumbnailUrl":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2024\/02\/mirtazapine-interactions.png","keywords":["Depression","Drug interactions"],"articleSection":["Drug Info"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.singlecare.com\/blog\/mirtazapine-interactions\/","url":"https:\/\/www.singlecare.com\/blog\/mirtazapine-interactions\/","name":"Mirtazapine interactions to avoid | SingleCare","isPartOf":{"@id":"https:\/\/www.singlecare.com\/blog\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.singlecare.com\/blog\/mirtazapine-interactions\/#primaryimage"},"image":{"@id":"https:\/\/www.singlecare.com\/blog\/mirtazapine-interactions\/#primaryimage"},"thumbnailUrl":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2024\/02\/mirtazapine-interactions.png","datePublished":"2024-02-20T13:59:58+00:00","dateModified":"2024-10-25T14:08:03+00:00","description":"Mirtazapine (Remeron) interacts with MAOIs, benzodiazepines, Warfarin, and alcohol, Here\u2019s what you should not take with mirtazapine to avoid side effects.","breadcrumb":{"@id":"https:\/\/www.singlecare.com\/blog\/mirtazapine-interactions\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.singlecare.com\/blog\/mirtazapine-interactions\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.singlecare.com\/blog\/mirtazapine-interactions\/#primaryimage","url":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2024\/02\/mirtazapine-interactions.png","contentUrl":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2024\/02\/mirtazapine-interactions.png","width":1920,"height":1080,"caption":"Rx prescription pad with Rx pills: Mirtazapine interactions"},{"@type":"BreadcrumbList","@id":"https:\/\/www.singlecare.com\/blog\/mirtazapine-interactions\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.singlecare.com\/blog\/"},{"@type":"ListItem","position":2,"name":"Mirtazapine interactions to avoid"}]},{"@type":"WebSite","@id":"https:\/\/www.singlecare.com\/blog\/#website","url":"https:\/\/www.singlecare.com\/blog\/","name":"The Checkup, a health blog by SingleCare","description":"Read the latest in prescription, wellness, and healthcare news","publisher":{"@id":"https:\/\/www.singlecare.com\/blog\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.singlecare.com\/blog\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.singlecare.com\/blog\/#organization","name":"SingleCare","url":"https:\/\/www.singlecare.com\/blog\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.singlecare.com\/blog\/#\/schema\/logo\/image\/","url":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2020\/01\/placeholderimage-1.jpg","contentUrl":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2020\/01\/placeholderimage-1.jpg","width":1200,"height":630,"caption":"SingleCare"},"image":{"@id":"https:\/\/www.singlecare.com\/blog\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/singlecare","https:\/\/x.com\/SingleCare","https:\/\/www.instagram.com\/singlecare\/?hl=en","https:\/\/www.linkedin.com\/company\/singlecare\/","https:\/\/www.youtube.com\/channel\/UCd9kiPIjCQw95-2BHCYePKA"]},{"@type":"Person","@id":"https:\/\/www.singlecare.com\/blog\/#\/schema\/person\/5ff7c7bb5ce0c66a6962ecf7c8d7941e","name":"Christie Falzone","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/2e99585820d49affcf442acba86e464b68d836bf071db26829d667da12209555?s=96&d=mm&r=gf47683752158743086d9c95bc1ebdaa7","url":"https:\/\/secure.gravatar.com\/avatar\/2e99585820d49affcf442acba86e464b68d836bf071db26829d667da12209555?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/2e99585820d49affcf442acba86e464b68d836bf071db26829d667da12209555?s=96&d=mm&r=g","caption":"Christie Falzone"},"description":"Christie Falzone recently graduated summa cum laude from Old Dominion University in Norfolk, Virginia, with a bachelor\u2019s degree in professional writing. During her time in college, she developed a passion for helping children and volunteers as a Court Appointed Special Advocate on behalf of foster youth.","url":"https:\/\/www.singlecare.com\/blog\/author\/cfalzone\/"}]}},"_links":{"self":[{"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/posts\/626768","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/users\/133"}],"replies":[{"embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/comments?post=626768"}],"version-history":[{"count":0,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/posts\/626768\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/media\/626780"}],"wp:attachment":[{"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/media?parent=626768"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/categories?post=626768"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/tags?post=626768"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/coauthors?post=626768"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}