{"id":626836,"date":"2024-02-19T09:30:22","date_gmt":"2024-02-19T14:30:22","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=626836"},"modified":"2025-02-12T18:44:31","modified_gmt":"2025-02-12T23:44:31","slug":"vitamins-for-depression","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/vitamins-for-depression\/","title":{"rendered":"8 vitamins for depression"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Depression is one of the most common mental health conditions. A National Institute of Mental Health survey found that in one year 21 million adults\u2014or 8.3% of American adults\u2014experienced a <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/depression-treatment-and-medications\"><span style=\"font-weight: 400;\">major depressive disorder<\/span><\/a><span style=\"font-weight: 400;\"> episode. It is more than just feeling sad; it\u2019s a psychiatric disorder with symptoms that can be severe and can seriously affect your ability to function in daily life, socially, and at work. Thankfully, depression is treatable. <\/span><\/p>\n<p><span style=\"font-weight: 400;\">The <\/span><span style=\"font-weight: 400;\">most effective depression treatments are psychotherapy and medication<\/span><span style=\"font-weight: 400;\">\u2014often a combination of the two. Lifestyle changes that improve your overall health and well-being can also help treat symptoms, including vitamins for depression. Taking dietary supplements shouldn\u2019t be the only way you treat depression, but they do have their place, especially if you are deficient in certain vitamins or minerals. Keep reading to learn which supplements could help.<\/span><\/p>\n<h2 id=\"8-vitamins-and-minerals-for-depression\"><span style=\"font-weight: 400;\">8 vitamins and minerals for depression<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">It\u2019s essential to emphasize that depression is a serious mental illness, and vitamins are not a cure-all. You should always see a mental health professional for a comprehensive treatment plan that includes therapy and medication. Then, you can work with your provider to add supplements to your regimen as needed.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Though vitamins and minerals can\u2019t cure depression, they can play a significant role in managing it, says <\/span><a href=\"https:\/\/solacetreatmentcenter.com\/reviewer\/dr-clifford-feldman\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Clifford Feldman, MD<\/span><\/a><span style=\"font-weight: 400;\">, board-certified psychiatrist and medical director at<\/span> <a href=\"https:\/\/solacetreatmentcenter.com\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Solace Treatment<\/span> <span style=\"font-weight: 400;\">Center<\/span><\/a><span style=\"font-weight: 400;\"> in Whittier, California. \u201cThey help by supporting the body&#8217;s natural production of neurotransmitters such as serotonin, dopamine, and norepinephrine, which are responsible for regulating mood,\u201d he explains.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Here are the eight best vitamins to try for depression.<\/span><\/p>\n<h3 id=\"1-vitamin-d\"><span style=\"font-weight: 400;\">1. Vitamin D<\/span><\/h3>\n<p><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/vitamin-d\"><span style=\"font-weight: 400;\">Vitamin D coupons<\/span><\/a><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9468237\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Research<\/span><\/a><span style=\"font-weight: 400;\"> shows that people with low vitamin D levels have a higher risk of developing symptoms of depression. \u201cVitamin D, also known as the sunshine vitamin, is important for brain function,\u201d says <\/span><a href=\"http:\/\/somamandalmd.com\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Soma Mandal, MD,<\/span><\/a><span style=\"font-weight: 400;\"> an internist at Summit Health in Berkeley Heights, New Jersey. \u201cLow vitamin D can cause fatigue and is associated with depression and seasonal affective disorders.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If you think you might be <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/how-much-vitamin-d-should-i-take\/\"><span style=\"font-weight: 400;\">deficient in vitamin D<\/span><\/a><span style=\"font-weight: 400;\">, check with a healthcare provider about how to supplement. According to the National Institutes of Health (NIH), the daily recommended vitamin D dosage for adults is <\/span><a href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminD-HealthProfessional\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">600 or 800 IUs per day<\/span><\/a><span style=\"font-weight: 400;\">. However, more is often recommended if you are vitamin D deficient. Just keep in mind that vitamin D may interact with certain medications, including weight loss drugs, <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/statins\"><span style=\"font-weight: 400;\">statins<\/span><\/a><span style=\"font-weight: 400;\">, steroids, and certain diuretics, so you should always consult with your healthcare provider or pharmacist before taking this supplement.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\t\t<div class=\"singlecare-dynamic-newsletter-wrapper sin-newsletter-wrapper\">\n\t\t\t<span class=\"heading\">Get our mental health newsletter<\/span>\n\t\t\t<form class=\"form-wrapper\" data-newsletter-form=\"1\" data-subsource=\"Mental Health Newsletter\">\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<label for=\"dynamic-email\">Email<\/label>\n\t\t\t\t\t<input type=\"email\" id=\"dynamic-email\" class=\"email\" required>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<input class=\"submit-form-btn\" type=\"submit\" value=\"Click to sign up\">\n\t\t\t\t<\/div>\n\t\t\t<\/form>\n\t\t\t<p class=\"success-message\" aria-live=\"polite\"><\/p>\n\t\t<\/div>\n\t<\/span><\/p>\n<h3 id=\"2-b12\"><span style=\"font-weight: 400;\">2. B12<\/span><\/h3>\n<p><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/vitamin-b12\"><span style=\"font-weight: 400;\">B12 coupons<\/span><\/a><\/p>\n<p><span style=\"font-weight: 400;\">\u201cResearch has shown that supplementing with vitamin B12 can delay the onset of depression in individuals with B12 deficiency, explains <\/span><a href=\"https:\/\/www.linkedin.com\/in\/shaykevich\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Yelena Wheeler, MPH, RDN<\/span><\/a><span style=\"font-weight: 400;\">, a registered dietitian based in Los Angeles, California. For example,<\/span> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20519557\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">one study<\/span><\/a><span style=\"font-weight: 400;\"> found that older adults who supplement with B12 and B6 tend to have a lower risk of developing depression over the next 12 years.<\/span> <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7688056\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">A research review<\/span><\/a><span style=\"font-weight: 400;\"> found that B12 supplementation may improve the effects of<\/span> <a href=\"https:\/\/www.singlecare.com\/blog\/common-depression-medication\/\"><span style=\"font-weight: 400;\">antidepressant medication<\/span><\/a><span style=\"font-weight: 400;\">, such as selective serotonin reuptake inhibitors (<\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/ssris\"><span style=\"font-weight: 400;\">SSRIs<\/span><\/a><span style=\"font-weight: 400;\">).<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The recommended daily intake for adults is <\/span><a href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminB12-HealthProfessional\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">2.4 mcg of B12 daily<\/span><\/a><span style=\"font-weight: 400;\">. If you are taking gastric acid inhibitors or metformin, you should check with a healthcare provider before supplementing with vitamin B12, as these medications can reduce the absorption of B12 into the body.\u00a0\u00a0<\/span><\/p>\n<h3 id=\"3-folic-acid\"><span style=\"font-weight: 400;\">3. Folic acid<\/span><\/h3>\n<p><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/folic-acid\"><span style=\"font-weight: 400;\">Folic acid supplements<\/span><\/a><\/p>\n<p><span style=\"font-weight: 400;\">\u201cFolate helps to produce neurotransmitters in the brain,\u201d Dr. Feldman says. \u201cInadequate folate<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">intake has been linked to mental health conditions like depression and<\/span> <span style=\"font-weight: 400;\">schizophrenia.\u201d <\/span><span style=\"font-weight: 400;\">Indeed,<\/span> <a href=\"https:\/\/www.mdpi.com\/2072-6643\/15\/17\/3859\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">studies have found<\/span><\/a><span style=\"font-weight: 400;\"> that people living with depression often have low levels of folate, also known as vitamin B9, which adds to the evidence that supplementation may help improve symptoms of depression.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The average adult should take <\/span><a href=\"https:\/\/ods.od.nih.gov\/factsheets\/Folate-HealthProfessional\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">400 mcg of folic acid per day<\/span><\/a><span style=\"font-weight: 400;\">, according to the National Institutes of Health (NIH). If you are pregnant, you should take 600 mcg daily; breastfeeding individuals need 500 mcg daily. Folic acid supplements can interact with a few medications, including <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/methotrexate\/dosage\"><span style=\"font-weight: 400;\">methotrexate<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/anticonvulsants\"><span style=\"font-weight: 400;\">antiepileptic medications<\/span><\/a><span style=\"font-weight: 400;\">, and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/sulfasalazine\/what-is\"><span style=\"font-weight: 400;\">sulfasalazine<\/span><\/a><span style=\"font-weight: 400;\">. In addition to folic acid supplements, you can get folate from foods like leafy greens, legumes, and citrus fruits.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/folic-acid-foods\/\"><b>10 folate-rich foods<\/b><\/a><\/p>\n<h3 id=\"4-magnesium\"><span style=\"font-weight: 400;\">4. Magnesium<\/span><\/h3>\n<p><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/magnesium\"><span style=\"font-weight: 400;\">Magnesium coupons<\/span><\/a><\/p>\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0899900716302441\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">A study<\/span><\/a><span style=\"font-weight: 400;\"> found that people who took 500 mg of magnesium oxide vitamins daily for eight weeks had improvements in symptoms of depression. However, these patients were known to be deficient in magnesium. More research is needed to determine if this supplement would improve symptoms for those who are not magnesium deficient.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Daily magnesium recommendations are <\/span><a href=\"https:\/\/ods.od.nih.gov\/factsheets\/Magnesium-HealthProfessional\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">400 to 420 mg for adult men and 310 to 320 mg for adult women<\/span><\/a><span style=\"font-weight: 400;\"> who are not pregnant. If you are taking certain medications, you should take precautions if you are supplementing with high doses of magnesium. Magnesium is known to interact with <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/bisphosphonates\"><span style=\"font-weight: 400;\">bisphosphonates<\/span><\/a><span style=\"font-weight: 400;\">, antibiotics, diuretics, and <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/proton-pump-inhibitors\"><span style=\"font-weight: 400;\">proton pump inhibitors<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h3 id=\"5-zinc\"><span style=\"font-weight: 400;\">5. Zinc<\/span><\/h3>\n<p><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/zinc\"><span style=\"font-weight: 400;\">Zinc coupons<\/span><\/a><\/p>\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0163834320301146\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Research<\/span><\/a><span style=\"font-weight: 400;\"> finds that zinc deficiency is linked with depressive symptoms\u2014such as sadness, hopelessness, and feeling numb\u2014and that supplementing can decrease these symptoms. Zinc supplementation can also decrease depression symptoms for people on antidepressants, as zinc may be able to enhance the effects of antidepressants like selective serotonin reuptake inhibitors (SSRIs), Wheeler notes.<\/span><span style=\"font-weight: 400;\">\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Adult men should take <\/span><a href=\"https:\/\/ods.od.nih.gov\/factsheets\/Zinc-HealthProfessional\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">11 mg of zinc daily<\/span><\/a><span style=\"font-weight: 400;\">, and adult women need 8mg. Zinc may interact with certain antibiotics and diuretics, leading to decreased zinc absorption, so make sure to talk to a health professional if you are considering zinc supplementation while taking other medications.\u00a0<\/span><\/p>\n<h3 id=\"6-omega-3-fatty-acids\"><span style=\"font-weight: 400;\">6. Omega-3 fatty acids<\/span><\/h3>\n<p><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/omega-3\"><span style=\"font-weight: 400;\">Omega-3 coupons<\/span><\/a><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9962071\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">There is evidence that omega-3 supplements<\/span><\/a><span style=\"font-weight: 400;\">, also known as fish oil, may help with depression. These fatty acids \u201care essential for brain health and can enhance the effectiveness of antidepressant medications,\u201d Dr. Mandel explains. Omega-3 fatty acids can also be found in foods like salmon, walnuts, flaxseeds, and chia seeds.<\/span><span style=\"font-weight: 400;\">\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The recommended daily dose of omega-3 fatty acids for adults is <\/span><a href=\"https:\/\/ods.od.nih.gov\/factsheets\/Omega3FattyAcids-HealthProfessional\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">1.6 grams for males and 1.1 grams<\/span><\/a><span style=\"font-weight: 400;\"> for females. People taking anticoagulants like warfarin should talk to their healthcare provider before taking omega-3 fatty acid supplements due to a potentially increased risk of bleeding.<\/span><\/p>\n<h3 id=\"7-turmeric\"><span style=\"font-weight: 400;\">7. Turmeric<\/span><\/h3>\n<p><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/turmeric\"><span style=\"font-weight: 400;\">Turmeric coupons<\/span><\/a><\/p>\n<p><span style=\"font-weight: 400;\">\u201cTurmeric contains an active compound called curcumin, which has potential benefits, including depression,\u201d Dr. Mandel explains.<\/span> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31423805\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Research<\/span><\/a><span style=\"font-weight: 400;\"> has found curcumin to be effective in relieving symptoms of depression and anxiety in people with major depressive disorder. It also has the potential to help with anxiety. Moreover, turmeric is generally well tolerated by people who use it as a supplement. However, as Dr. Mandel points out, the research we have so far is based on small sample sizes. More research is needed to confirm the link between turmeric and depression.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/turmeric-benefits\/\"><b>14 health benefits of turmeric<\/b><\/a><\/p>\n<h3 id=\"8-probiotics\"><span style=\"font-weight: 400;\">8. Probiotics\u00a0<\/span><\/h3>\n<p><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/probiotic\"><span style=\"font-weight: 400;\">Probiotics coupons<\/span><\/a><\/p>\n<p><span style=\"font-weight: 400;\">Though not a vitamin or mineral,<\/span> <a href=\"https:\/\/www.singlecare.com\/blog\/probiotics-do-they-work\/\"><span style=\"font-weight: 400;\">probiotics<\/span><\/a><span style=\"font-weight: 400;\"> (which contain live bacteria and yeasts) may be helpful for people with depression. More research is needed, but there is some<\/span> <a href=\"https:\/\/nutrition.bmj.com\/content\/3\/2\/351\"><span style=\"font-weight: 400;\">evidence<\/span><\/a><span style=\"font-weight: 400;\"> that <\/span><span style=\"font-weight: 400;\">these supplements can balance your gut microbiome, which may help with certain mood disorders and mood regulation.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">How might this work exactly? <\/span><span style=\"font-weight: 400;\">\u201c<\/span><span style=\"font-weight: 400;\">Imbalances in the gut microbiome can cause inflammation and changes in<\/span> <span style=\"font-weight: 400;\">neurotransmitter levels, contributing to mood disorders such as depression,\u201d Dr. Feldman explains. <\/span><span style=\"font-weight: 400;\">\u201c<\/span><span style=\"font-weight: 400;\">Probiotics may help alleviate depression symptoms and improve overall <\/span><span style=\"font-weight: 400;\">mental health by rebalancing the gut microbiome.\u201d<\/span><\/p>\n<h2 id=\"who-should-avoid-vitamins-for-depression\"><span style=\"font-weight: 400;\">Who should avoid vitamins for depression?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">On their own, vitamins and supplements usually aren\u2019t harmful, except when taken in larger than recommended dosages or among certain vulnerable populations, such as<\/span> <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6618111\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">pregnant or breastfeeding individuals<\/span><\/a><span style=\"font-weight: 400;\">. Anyone with an underlying health condition should talk to their healthcare provider before taking a vitamin supplement. \u201cYou should also consult with a physician if you are taking any other medications to make sure there are no contraindications to taking these vitamins or supplements,\u201d Wheeler advises.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Again, it should be emphasized that vitamins are not meant to be the sole treatment for depression, and people should be wary of any supplement that claims to cure depression. It\u2019s also important to remember that<\/span> <a href=\"https:\/\/www.fda.gov\/food\/information-consumers-using-dietary-supplements\/questions-and-answers-dietary-supplements\"><span style=\"font-weight: 400;\">the FDA doesn\u2019t regulate or approve supplements<\/span><\/a><span style=\"font-weight: 400;\"> before they are marketed to consumers. Still, there are a few independent organizations that do quality testing on supplements to make sure they contain the ingredients listed on the label and don\u2019t have any contaminants. You can look for vitamins that have been approved by consumerlab.com, NSF International, or U.S. Pharmacopeia.<\/span><\/p>\n<h2 id=\"bottom-line-ask-your-healthcare-provider-for-help\"><span style=\"font-weight: 400;\">Bottom line: Ask your healthcare provider for help<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Your healthcare provider or pharmacist can help you decide which vitamin or supplement to take\u2014including which manufacturer to trust. Don\u2019t hesitate to reach out to them for a recommendation.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Finally, if you are living with depression or other mental health conditions or mood disorders, make sure you are getting treatment from a licensed mental health professional or other health professional. If you experience thoughts of self-harm or suicide, contact the 24-hour helpline at 988, or go to the nearest emergency room.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Depression is one of the most common mental health conditions. A National Institute of Mental Health survey found that in one year 21 million adults\u2014or 8.3% of American adults\u2014experienced a major depressive disorder episode. It is more than just feeling sad; it\u2019s a psychiatric disorder with symptoms that can be severe and can seriously affect [&hellip;]<\/p>\n","protected":false},"author":135,"featured_media":626579,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[11],"tags":[451,450,812],"coauthors":[20899],"class_list":["post-626836","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-wellness","tag-depression","tag-mental-health","tag-supplements","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>8 vitamins and minerals for depression<\/title>\n<meta name=\"description\" content=\"Low vitamin D and B-12 levels are linked to depression. 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