{"id":626944,"date":"2024-02-20T17:39:29","date_gmt":"2024-02-20T22:39:29","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=626944"},"modified":"2024-10-25T10:07:26","modified_gmt":"2024-10-25T14:07:26","slug":"new-psoriasis-medication","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/new-psoriasis-medication\/","title":{"rendered":"New psoriasis medication: Your options explained"},"content":{"rendered":"

The need for better psoriasis treatments has been long-standing for years. Now, options for effective psoriasis relief have multiplied. Due to these recent developments, <\/span>8 million Americans and 30 million people worldwide<\/span><\/a> with psoriasis have reason for optimism. Patients affected by this skin disease span all ages and genders, often having a family history of the condition and many times having an <\/span>associated risk factor<\/span><\/a> like obesity, smoking, and alcohol use. Regardless of your circumstances, <\/span>if you have psoriasis<\/span><\/a>, you deserve to be introduced to the new psoriasis medication.<\/span><\/p>\n

Current treatments for psoriasis<\/span><\/h2>\n

Psoriasis<\/span><\/a> is not a uniform disease. <\/span>Variants<\/span><\/a> include plaque psoriasis with <\/span>thick, scaly areas<\/span><\/a>, guttate psoriasis with temporary outbreaks, inverse psoriasis that affects skin folds, and pustular psoriasis that can be generalized or limited to the palms and soles. Associated conditions like psoriatic arthritis can be part of the picture, too. <\/span><\/p>\n

Treatment options are diverse as well. Topical therapies, like <\/span>corticosteroids<\/span><\/a>, emollients, and <\/span>retinoids<\/span><\/a>, have traditionally attacked this disease via anti-inflammatory mechanisms, moisturization, or inhibition of skin cell proliferation, respectively. Systemic oral and injectable treatments, like methotrexate and <\/span>biologics<\/span><\/a>, target aspects of the immune system to reduce inflammation.<\/span><\/p>\n

Problems with existing psoriasis treatments<\/span><\/h2>\n

The problem with pre-existing psoriasis treatments has been that the relatively safe topical options weren’t always effective. Immunosuppressants like early biologics risked a multitude of serious side effects. Hence, the search was on for <\/span>new medication for psoriasis<\/span> that combined tolerability with high efficacy.<\/span><\/p>\n

Newly approved psoriasis medication<\/span><\/h2>\n

In the past two years, new topical and systemic agents have been added to the list of options for psoriasis management. Their advantages are significant for individuals looking for a new treatment for psoriasis.<\/span><\/p>\n

Vtama<\/span><\/h3>\n

Approved by the Food and Drug Administration (FDA) in 2022 for use in adults, Vtama (tapinarof) is a topical cream that treats plaque psoriasis by decreasing inflammation. It accomplishes this by modifying interleukin 17 (IL-17) cytokines, which are the immune system’s messenger proteins. Vtama offers another topical treatment option to help avoid the topical corticosteroid side effect of skin atrophy or thinning.<\/span><\/p>\n

Zoryve<\/span><\/h3>\n

Zoryve (roflumilast) is also a topical cream for plaque psoriasis in adults. It, too, got approval from the FDA in 2022. The drug’s mechanism of action as a phosphodiesterase 4 inhibitor means it is not a steroid. This important distinction allows it to be used in skin folds, unlike topical steroids, which cannot be used due to skin atrophy side effects. <\/span><\/p>\n

Sotyktu<\/span><\/h3>\n

By inhibiting tyrosine kinase 2, and thereby modifying cytokines like interleukin 23, Sotyktu (deucravacitinib) acts as an effective anti-inflammatory treatment for moderate-to-severe plaque psoriasis. The FDA approved this oral tablet as an anti-psoriatic medication in 2022. <\/span>Clinical trials<\/span><\/a> leading to its approval demonstrated efficacy and safety.<\/span><\/p>\n

Bimzelx<\/span><\/h3>\n

Bimzelx (bimekizumab) is a monoclonal antibody that inhibits IL-17 to reduce psoriasis inflammation. The treatment requires a subcutaneous injection every four weeks for 16 weeks, and then every eight weeks thereafter. FDA approval was granted in 2023 for moderate to severe plaque psoriasis in adults.<\/span><\/p>\n

Compare new psoriasis medications<\/span><\/h2>\n

According to the medical reference <\/span>UpToDate<\/span><\/a>, psoriasis medications come in various formulations, with most all aiming to reduce the inflammatory cascade in psoriasis. Reviewing and comparing options may help you narrow down which new medication for psoriasis to consult your healthcare provider about.<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\n

Common psoriasis medications<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n

Drug name<\/b><\/td>\nDrug class<\/b><\/td>\nForm<\/b><\/td>\nSafety & side effect highlights<\/b><\/td>\nSingleCare savings<\/b><\/td>\n<\/tr>\n
Clobex (clobetasol) 0.05% liquid<\/span><\/td>\nCorticosteroid<\/span><\/td>\nTopical<\/span><\/td>\nSkin atrophy with extended use<\/span><\/td>\nGet Clobex coupon<\/span><\/a><\/td>\n<\/tr>\n
Vanos (fluocinonide) 0.1% cream<\/span><\/td>\nCorticosteroid<\/span><\/td>\nTopical<\/span><\/td>\nSkin atrophy with extended use<\/span><\/td>\nGet Vanos coupon<\/span><\/a><\/td>\n<\/tr>\n
Sorilux (calcipotriene) foam<\/span><\/td>\nVitamin D analog<\/span><\/td>\nTopical<\/span><\/td>\nSkin irritation<\/span><\/td>\nGet Sorilux coupon<\/span><\/a><\/td>\n<\/tr>\n
Calcitriol ointment<\/span><\/td>\nVitamin D analog<\/span><\/td>\nTopical<\/span><\/td>\nSkin irritation<\/span><\/td>\nGet calcitriol coupon<\/span><\/a><\/td>\n<\/tr>\n
Psoriasin (tar)<\/span><\/td>\nCoal tar<\/span><\/td>\nTopical<\/span><\/td>\nCan stain skin, hair, and clothing; unpleasant odor<\/span><\/td>\nGet Psoriasin coupon<\/span><\/a><\/td>\n<\/tr>\n
Tazorac (tazarotene) cream<\/span><\/td>\nRetinoid<\/span><\/td>\nTopical<\/span><\/td>\nSkin irritation, sun sensitivity, avoid in pregnancy and breastfeeding<\/span><\/td>\nGet Tazorac coupon<\/span><\/a><\/td>\n<\/tr>\n
Tacrolimus 0.1% ointment<\/span><\/td>\nCalcineurin inhibitor<\/span><\/td>\nTopical<\/span><\/td>\nAvoids skin atrophy but has an FDA boxed warning about lymphoma risk, although <\/span>studies<\/span><\/a> have not confirmed the risk<\/span><\/td>\nGet tacrolimus coupon<\/span><\/a><\/td>\n<\/tr>\n
Elidel (pimecrolimus) 1% cream<\/span><\/td>\nCalcineurin inhibitor<\/span><\/td>\nTopical<\/span><\/td>\nAvoids skin atrophy but has an FDA boxed warning about lymphoma risk, although <\/span>studies<\/span><\/a> have not confirmed the risk<\/span><\/td>\nGet Elidel coupon<\/span><\/a><\/td>\n<\/tr>\n
Vtama (tapinarof) 0.1% cream<\/span><\/td>\nAryl hydrocarbon receptor-modulating agent<\/span><\/td>\nTopical<\/span><\/td>\nSkin rash, headache<\/span><\/td>\nGet Vtama coupon<\/span><\/a><\/td>\n<\/tr>\n
Zoryve (roflumilast) 0.3% cream<\/span><\/td>\nPhosphodiesterase 4 inhibitor<\/span><\/td>\nTopical<\/span><\/td>\nDiarrhea, headache<\/span><\/td>\nGet Zoryve coupon<\/span><\/a><\/td>\n<\/tr>\n
Methotrexate tablets<\/span><\/td>\nFolic acid antagonist<\/span><\/td>\nOral<\/span><\/td>\nMultiple FDA warnings, including liver toxicity, lung toxicity, intestinal toxicity, reduced clearance with kidney disease, increased infection risk, and severe skin and allergic reactions<\/span><\/td>\nGet methotrexate coupon<\/span><\/a><\/td>\n<\/tr>\n
Acitretin capsules<\/span><\/td>\nRetinoid<\/span><\/td>\nOral<\/span><\/td>\nMultiple FDA warnings including liver toxicity, strict avoidance in pregnancy, strict precautions against pregnancy in women of childbearing age, avoidance of alcohol by women while taking, and avoidance of blood donation during and for at least 3 years after treatment <\/span><\/td>\nGet acitretin coupon<\/span><\/a><\/td>\n<\/tr>\n
Neoral (cyclosporine) tablets<\/span><\/td>\nT cell immune suppressant<\/span><\/td>\nOral<\/span><\/td>\nMultiple FDA warnings including kidney toxicity, increased infection and cancer risk, and hypertension risk<\/span><\/td>\nGet Neoral coupon<\/span><\/a><\/td>\n<\/tr>\n
Otezla (apremilast) tablets<\/span><\/td>\nPhosphodiesterase 4 inhibitor<\/span><\/td>\nOral<\/span><\/td>\nDiarrhea, nausea, headache, depression, and weight loss<\/span><\/td>\nGet Otezla coupon<\/span><\/a><\/td>\n<\/tr>\n
Enbrel (etanercept) injection<\/span><\/td>\nTNF-alpha inhibitor<\/span><\/td>\nSubcutaneous injection<\/span><\/td>\nFDA warnings regarding increased infection and cancer risk<\/span><\/td>\nGet Enbrel coupon<\/span><\/a><\/td>\n<\/tr>\n
Remicade (infliximab) injection<\/span><\/td>\nTNF-alpha inhibitor<\/span><\/td>\nIntravenous infusion<\/span><\/td>\nFDA warnings regarding increased infection and cancer risk<\/span><\/td>\nGet a SingleCare discount card<\/span><\/a><\/td>\n<\/tr>\n
Humira (adalimumab) injection<\/span><\/td>\nTNF-alpha inhibitor<\/span><\/td>\nSubcutaneous injection<\/span><\/td>\nFDA warnings regarding increased infection and cancer risk<\/span><\/td>\nGet Humira coupon<\/span><\/a><\/td>\n<\/tr>\n
Cimzia (certolizumab) injection<\/span><\/td>\nTNF-alpha inhibitor<\/span><\/td>\nSubcutaneous injection<\/span><\/td>\nFDA warnings regarding increased infection and cancer risk<\/span><\/td>\nGet Cimzia coupon<\/span><\/a><\/td>\n<\/tr>\n
Cosentyx (secukinumab) injection<\/span><\/td>\nIL-17A inhibitor<\/span><\/td>\nSubcutaneous injection<\/span><\/td>\nDiarrhea, infection risk, low immune cell count, severe eczema, inflammatory bowel disease<\/span><\/td>\nGet SingleCare discount card<\/span><\/a><\/td>\n<\/tr>\n
Taltz (ixekizumab) injection<\/span><\/td>\nIL-17A inhibitor<\/span><\/td>\nSubcutaneous injection<\/span><\/td>\nNausea, infection risk, low immune or clotting cell count, inflammatory bowel disease<\/span><\/td>\nGet SingleCare discount card<\/span><\/a><\/td>\n<\/tr>\n
Siliq (brodalumab)<\/span><\/p>\n

injection<\/span><\/td>\n

IL-17A inhibitor<\/span><\/td>\nSubcutaneous injection<\/span><\/td>\nFDA warning about suicidality, diarrhea, infection risk, inflammatory bowel disease<\/span><\/td>\nGet Siliq coupon<\/span><\/a><\/td>\n<\/tr>\n
Bimzelx (bimekizumab)<\/span><\/td>\nIL-17A and IL-17F inhibitor<\/span><\/td>\nSubcutaneous injection<\/span><\/td>\nFDA warning about suicidality, headache, infection risk, inflammatory bowel disease<\/span><\/td>\nGet Bimzelx coupon<\/span><\/a><\/td>\n<\/tr>\n
Stelara (ustekinumab) injection<\/span><\/td>\nIL-23 inhibitor<\/span><\/td>\nSubcutaneous injection<\/span><\/td>\nInfection risk, cancer risk, headache, diarrhea<\/span><\/td>\nGet SingleCare discount card<\/span><\/a><\/td>\n<\/tr>\n
Tremfya (guselkumab) injection<\/span><\/td>\nIL-23 inhibitor<\/span><\/td>\nSubcutaneous injection<\/span><\/td>\nInfection risk, headache, joint pains<\/span><\/td>\nGet Tremfya coupon<\/span><\/a><\/td>\n<\/tr>\n
Ilumya (tildrakizumab) injection<\/span><\/td>\nIL-23 inhibitor<\/span><\/td>\nSubcutaneous injection<\/span><\/td>\nInfection risk, diarrhea<\/span><\/td>\nGet SingleCare discount card<\/span><\/a><\/td>\n<\/tr>\n
Skyrisi (risankizumab) injection<\/span><\/td>\nIL-23 inhibitor<\/span><\/td>\nSubcutaneous injection<\/span><\/td>\nInfection risk, joint pain, headache, anemia<\/span><\/td>\nGet Skyrizi coupon<\/span><\/a><\/td>\n<\/tr>\n
Sotyktu (deucravacitinib) tablets<\/span><\/td>\nTyrosine kinase inhibitor<\/span><\/td>\nOral<\/span><\/td>\nInfection risk, muscle enzyme elevation, triglyceride elevation<\/span><\/td>\nGet Sotyktu coupon<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/span><\/p>\n

Ask your healthcare provider about new psoriasis medication<\/span><\/h2>\n

The plethora of new treatments for psoriasis is impressive when compared with the options available twenty years ago. Considering how the drugs are administered and what side effects are risked can make it easier to narrow down the list to a few options that you might feel comfortable trying. Have a conversation with your healthcare provider to review more details about the new psoriasis medication on the market and make the best choice together.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

The need for better psoriasis treatments has been long-standing for years. Now, options for effective psoriasis relief have multiplied. Due to these recent developments, 8 million Americans and 30 million people worldwide with psoriasis have reason for optimism. Patients affected by this skin disease span all ages and genders, often having a family history of […]<\/p>\n","protected":false},"author":149,"featured_media":626949,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[790,20955,15105],"coauthors":[20732],"class_list":["post-626944","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-chronic-disease","tag-inflammation","tag-skincare","wpautop"],"acf":[],"yoast_head":"\nNew psoriasis medication: Your options explained<\/title>\n<meta name=\"description\" content=\"More than 8 million Americans have psoriasis. 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