{"id":626991,"date":"2024-02-27T12:27:05","date_gmt":"2024-02-27T17:27:05","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=626991"},"modified":"2025-12-17T16:37:12","modified_gmt":"2025-12-17T21:37:12","slug":"rexulti-alternatives","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/rexulti-alternatives\/","title":{"rendered":"Rexulti alternatives: What can I take instead of Rexulti?"},"content":{"rendered":"

Rexulti<\/span><\/a> (brexpiprazole) is a brand-name prescription drug made by Otsuka America Pharmaceutical. Rexulti is approved by the Food and Drug Administration (FDA) as an adjunct to be used along with an <\/span>antidepressant medicine<\/span><\/a> to treat <\/span>major depressive disorder<\/span><\/a> (MDD, also known as depression) in adults. It is also FDA approved to treat <\/span>schizophrenia<\/span><\/a> in adults and children ages 13 and older, and to treat agitation that may occur with <\/span>dementia due to Alzheimer\u2019s disease<\/span><\/a>. Rexulti is part of a group of drugs known as <\/span>atypical or second-generation antipsychotics<\/span><\/a>.<\/span><\/p>\n

While Rexulti is an effective treatment for many people, some may have better options. For various reasons, such as cost, side effect profile, or allergy to the active or inactive ingredients, discussing an alternative medicine with one\u2019s healthcanare provider may be necessary.<\/span><\/p>\n

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Save up to 80% on Rexulti with SingleCare<\/p>\n\t\t\t

Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t

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\n\t\t\t\t\tRexulti 1 mg (30 Tablets)\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t
\n\t\t\t\"Kroger\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t$1471.43\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\ti<\/span>\n\t\t\t\t\tPrice with signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\tGet free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
\n\t\t\t
\n\t\t\t\"Harris\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t$1471.43\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\ti<\/span>\n\t\t\t\t\tPrice with signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\tGet free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\tSee Rexulti prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t<\/span><\/p>\n

What can I take in place of Rexulti?<\/span><\/h2>\n

There are other antipsychotic drugs available to treat MDD, schizophrenia, or agitation from dementia due to Alzheimer\u2019s disease if symptoms do not improve with Rexulti or if it cannot be tolerated. The table below compares Rexulti with some of the other FDA-approved atypical antipsychotic drugs.<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
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Compare Rexulti alternatives<\/span><\/h2>\n<\/th>\n<\/tr>\n<\/thead>\n

Drug name<\/b><\/td>\nUses<\/b><\/td>\nDosage*<\/b><\/td>\nSavings options<\/b><\/td>\n<\/tr>\n
Rexulti <\/a>(brexpiprazole)<\/strong><\/td>\nSchizophrenia, add-on treatment for depression, and agitation associated with dementia in Alzheimer’s disease<\/span><\/td>\n2 to 4 mg once daily<\/span><\/td>\nRexulti coupons<\/span><\/a><\/td>\n<\/tr>\n
Abilify <\/strong><\/span><\/a>(aripiprazole)<\/a><\/strong><\/td>\nSchizophrenia, bipolar disorder, add-on treatment for depression, irritability due to autistic disorder, Tourette\u2019s disorder<\/span><\/td>\n10 to 15 mg once daily for schizophrenia and bipolar disorder<\/span><\/td>\nAbilify coupons<\/span><\/a><\/td>\n<\/tr>\n
Caplyta<\/a> (lumateperone)<\/strong><\/td>\nSchizophrenia, bipolar depression<\/span><\/td>\n42 mg once daily<\/span><\/td>\nCaplyta coupons<\/span><\/a><\/td>\n<\/tr>\n
Clozaril <\/a>(clozapine)<\/a><\/strong><\/td>\nTreatment-resistant schizophrenia<\/span><\/td>\n12.5 mg once or twice daily and gradually increased<\/span><\/td>\nClozaril coupons<\/span><\/a><\/td>\n<\/tr>\n
Geodon <\/a>(ziprasidone)<\/a><\/strong><\/td>\nSchizophrenia, bipolar disorder<\/span><\/td>\n20 mg twice daily for schizophrenia; 40 to 80 mg twice daily for bipolar disorder<\/span><\/td>\nGeodon coupons<\/span><\/a><\/td>\n<\/tr>\n
Invega <\/a><\/strong>(paliperidone)<\/strong><\/span><\/a><\/td>\nSchizophrenia, schizoaffective disorder<\/span><\/td>\n3 to 6 mg once daily<\/span><\/td>\nInvega coupons<\/span><\/a><\/td>\n<\/tr>\n
Latuda <\/a>(lurasidone)<\/a><\/strong><\/td>\nSchizophrenia,<\/span><\/p>\n

bipolar depression<\/span><\/td>\n

40 to 160 mg once daily for schizophrenia; 20 to 120 mg for bipolar depression<\/span><\/td>\nLatuda coupons<\/span><\/a><\/td>\n<\/tr>\n
Saphris <\/a>(asenapine)<\/a><\/strong><\/td>\nSchizophrenia, bipolar disorder<\/span><\/td>\n5 to 10 mg sublingually (under the tongue) twice daily<\/span><\/td>\nSaphris coupons<\/span><\/a><\/td>\n<\/tr>\n
Risperdal <\/a>(risperidone)<\/a><\/strong><\/td>\nSchizophrenia, bipolar disorder, and irritability associated with autistic disorder<\/span><\/td>\n1 to 8 mg per day (once daily or divided into twice-daily doses)<\/span><\/td>\nRisperdal coupons<\/span><\/a><\/td>\n<\/tr>\n
Seroquel<\/a><\/strong><\/p>\n

(quetiapine)<\/a><\/strong><\/td>\n

Schizophrenia, bipolar disorder, bipolar depression, and add-on treatment for depression<\/span><\/td>\n150 to 750 mg daily, divided into 2 or 3 doses for schizophrenia; 200 to 400 mg twice daily for bipolar disorder<\/span><\/td>\nSeroquel coupons<\/span><\/a><\/td>\n<\/tr>\n
Vraylar <\/a>(cariprazine)<\/strong><\/td>\nSchizophrenia, bipolar disorder, bipolar depression, and add-on treatment for depression<\/span><\/td>\n1.5 to 6 mg once daily<\/span><\/td>\nVraylar coupons<\/span><\/a><\/td>\n<\/tr>\n
Zyprexa<\/a> (olanzapine)<\/a><\/strong><\/td>\nSchizophrenia, bipolar disorder, treatment-resistant depression<\/span><\/td>\n5 to 20 mg daily<\/span><\/td>\nZyprexa coupons<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

*Dosage may vary by factors such as age, weight, and reason for use.<\/span><\/em><\/small><\/small><\/p>\n

Other alternatives to Rexulti<\/span><\/h2>\n

Rexulti is an atypical, or second-generation, <\/span>antipsychotic<\/span><\/a>. This group of antipsychotics is newer and causes fewer movement-related side effects than the first-generation or typical antipsychotics. Examples of typical antipsychotics include:<\/span><\/p>\n