{"id":627191,"date":"2024-03-08T15:33:20","date_gmt":"2024-03-08T20:33:20","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=627191"},"modified":"2026-01-06T15:30:05","modified_gmt":"2026-01-06T20:30:05","slug":"ibuprofen-for-dogs","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/ibuprofen-for-dogs\/","title":{"rendered":"Can dogs take ibuprofen?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Though safe for humans, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/ibuprofen\"><span style=\"font-weight: 400;\">ibuprofen<\/span><\/a><span style=\"font-weight: 400;\"> (Motrin or Advil) and other human nonsteroidal anti-inflammatory (NSAID) pain relievers such as aspirin, naproxen (Aleve), or acetaminophen (Tylenol) should never be given to dogs. Even a low dose for a person (200 mg) could be toxic to a small dog.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Ibuprofen and other over-the-counter human NSAIDS are not FDA-approved for use in dogs. Veterinarians do not prescribe ibuprofen because other, <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/pain-relief-for-dogs-cats\/\"><span style=\"font-weight: 400;\">safer medications<\/span><\/a><span style=\"font-weight: 400;\"> are specifically formulated for dogs. Veterinarians can prescribe ibuprofen off-label to a dog, but if that happens, ask the vet about safer alternatives. Even a very low dose of ibuprofen will eventually cause ulcers in a dog if given for long enough. A very high dose\u2014for instance, if a dog chews open an ibuprofen bottle\u2014could quickly cause severe illness, kidney failure, seizures, coma, and death.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Ibuprofen poisoning is one of the <\/span><a href=\"https:\/\/www.cliniciansbrief.com\/columns\/6\/top-10-toxicoses\"><span style=\"font-weight: 400;\">most common drug poisonings<\/span><\/a><span style=\"font-weight: 400;\"> reported to the ASPCA Animal Poison Control Center. It\u2019s usually the result of accidental ingestion or a well-meaning owner using it to relieve a pet\u2019s pain in the mistaken belief that it\u2019s safe. Veterinarians typically consider ibuprofen poisoning a veterinary emergency, so if a dog has been given or eaten ibuprofen, call a veterinary poison helpline or seek emergency veterinary treatment.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/prescription\/ibuprofen\"><b>Save up to 80% on ibuprofen<\/b><\/a><\/p>\n<h2 id=\"is-ibuprofen-safe-for-dogs\"><span style=\"font-weight: 400;\">Is ibuprofen safe for dogs?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Ibuprofen is NOT safe for dogs to take.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Ibuprofen belongs to a class of drugs called nonsteroidal anti-inflammatory drugs (<\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/nsaids\"><span style=\"font-weight: 400;\">NSAIDs<\/span><\/a><span style=\"font-weight: 400;\">). Over-the-counter NSAIDS such as <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/aspirin\/what-is\"><span style=\"font-weight: 400;\">aspirin<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/naproxen\/what-is\"><span style=\"font-weight: 400;\">naproxen<\/span><\/a><span style=\"font-weight: 400;\">, and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/ibuprofen\/what-is\"><span style=\"font-weight: 400;\">ibuprofen<\/span><\/a><span style=\"font-weight: 400;\"> are common fixtures in household medicine cabinets because they are effective and have a wide margin of safety. Though it is safe in humans, no OTC NSAID is safe for animals. The only human NSAID FDA-approved for use in animals is prescription meloxicam.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In dogs, ibuprofen has a narrow range of safety in terms of dosage. Ibuprofen blocks the enzymes used to produce substances called <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/prostaglandins\"><span style=\"font-weight: 400;\">prostaglandins<\/span><\/a><span style=\"font-weight: 400;\"> that protect the stomach and intestines from stomach acid. Prostaglandins also <\/span><a href=\"https:\/\/www.cliniciansbrief.com\/article\/nsaid-therapy-dogs\"><span style=\"font-weight: 400;\">help increase blood flow to the kidneys<\/span><\/a><span style=\"font-weight: 400;\"> if the dog is dehydrated. Dogs given human NSAIDs are particularly prone to stomach acid damage and kidney damage because of these effects. The only publisheddose is <\/span><a href=\"https:\/\/www.dvm360.com\/view\/toxciology-brief-ibuprofen-toxicosis-dogs-cats-and-ferrets\"><span style=\"font-weight: 400;\">5 mg per kilogram of body weight daily<\/span><\/a><span style=\"font-weight: 400;\">. Even that dose (or lower) is high enough to eventually cause stomach ulcers and even perforation after a few weeks of dosing. A single dose of 25mg per kg, which equals 11mg per pound, can result in <\/span><a href=\"https:\/\/www.aspcapro.org\/sites\/default\/files\/t-toxbrief_0704.pdf\"><span style=\"font-weight: 400;\">symptoms of toxicity<\/span><\/a><span style=\"font-weight: 400;\"> and requires immediate veterinary care.\u00a0<\/span><\/p>\n<h3 id=\"side-effects-of-ibuprofen-in-dogs\"><span style=\"font-weight: 400;\">Side effects of ibuprofen in dogs<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Small doses of ibuprofen will, over time, produce digestive problems such as ulcers that are marked by side effects such as:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Abdominal pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lethargy<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Vomiting<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/blog\/dog-diarrhea\/\"><span style=\"font-weight: 400;\">Diarrhea<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Black and tarry stools<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">If a dog ingests too much ibuprofen all at once (more than 11 mg per pound), side effects can include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Abdominal pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diarrhea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Loss of appetite<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">A serious overdose of ibuprofen (more than 80 mg per pound) can cause significant kidney disease and even kidney failure. Besides those listed above, symptoms include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Blood in the vomit<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Black and tarry stools<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Increased drinking<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Increased urination or sudden lack of urine production<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Symptoms of low blood pressure or dehydration, such as lightheadedness<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">A severe ibuprofen overdose (more than 200 mg per pound) will cause neurological symptoms such as:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Depression<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/blog\/dog-seizures\/\"><span style=\"font-weight: 400;\">Seizures<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Loss of coordination<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Coma<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Death<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">If a dog has been given or accidentally ingested ibuprofen, immediately call a pet poison helpline, veterinarian, or veterinary emergency hospital.<\/span><\/p>\n<h3 id=\"interactions-of-ibuprofen-with-other-pet-meds\"><span style=\"font-weight: 400;\">Interactions of ibuprofen with other pet meds<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Ibuprofen should never be given to dogs because there\u2019s a high risk of poisoning and serious side effects. These side effects are more likely and could be more severe if the dog is taking other types of drugs, particularly:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Another type of NSAID, such as carprofen<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Any type of <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/corticosteroids\"><span style=\"font-weight: 400;\">corticosteroid<\/span><\/a><span style=\"font-weight: 400;\">, such as <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/prednisone\"><span style=\"font-weight: 400;\">prednisone<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Any kind of drug that can damage the kidneys, such as <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/aminoglycosides\"><span style=\"font-weight: 400;\">aminoglycoside antibiotics<\/span><\/a><span style=\"font-weight: 400;\"> (like <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/gentamicin-sulfate\"><span style=\"font-weight: 400;\">gentamicin<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Any kind of drug that causes fluid loss, such as a <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/diuretics\"><span style=\"font-weight: 400;\">diuretic<\/span><\/a><span style=\"font-weight: 400;\"> (like <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/furosemide\"><span style=\"font-weight: 400;\">furosemide<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/li>\n<\/ul>\n<h2 id=\"ibuprofen-alternatives-for-dogs\"><span style=\"font-weight: 400;\">Ibuprofen alternatives for dogs<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Because both OTC and most prescription human NSAIDs are not safe for dogs, pharmaceutical companies have formulated safer versions of these medications. They are FDA-approved for use in dogs at a particular dosage to relieve pain and swelling due to <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/arthritis-in-dogs\/\"><span style=\"font-weight: 400;\">osteoarthritis<\/span><\/a><span style=\"font-weight: 400;\"> or surgical procedures. However, veterinarians may use them off-label for <\/span><a href=\"https:\/\/www.cliniciansbrief.com\/article\/top-5-situations-judicious-nsaid-use\"><span style=\"font-weight: 400;\">other problems with pain or swelling, such as<\/span><\/a><span style=\"font-weight: 400;\"> muscle injury, bone injury, cancer, or fever. Some of these drugs can be used long-term, but others may need to be discontinued after a few days or weeks. All these alternatives require a prescription from a veterinarian.<\/span><\/p>\n<h3 id=\"dog-safe-prescription-nsaids-include\"><span style=\"font-weight: 400;\">Dog-safe prescription NSAIDs include:<\/span><\/h3>\n<ul>\n<li aria-level=\"1\"><b>Carprofen (brand names include Rimadyl, Rovera, Quellin, Vetprofen, Carprieve, Carprodyl)<\/b><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Administered as a tablet, chewable tablet, caplet, or injection<\/span><\/p>\n<ul>\n<li aria-level=\"1\"><b>Deracoxib (Coxiba, Deramaxx, Doxidyl, Ostimax)<\/b><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Administered as a chewable tablet<\/span><\/p>\n<ul>\n<li aria-level=\"1\"><b>Firocoxib (Firovet, Firox, Flexira, Osticoxib, Previcox)<\/b><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Administered as a chewable tablet<\/span><\/p>\n<ul>\n<li aria-level=\"1\"><b>Grapiprant (Galliprant)<\/b><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Administered as a tablet; FDA-approved only as a treatment for osteoarthritis<\/span><\/p>\n<ul>\n<li aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/meloxicam\"><b>Meloxicam<\/b><\/a><b> (Alloxate, Loxicom, Meloxidyl, Meloxivet, Metacam, Ostilox)<\/b><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Administered as an oral solution or injection; FDA-approved only as an <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/meloxicam-for-dogs\/\"><span style=\"font-weight: 400;\">osteoarthritis treatment in dogs<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Only meloxicam is used in both animals and humans. In both cases, healthcare professionals use the lowest effective dose for the shortest possible duration because of the risk of side effects.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Other painkillers approved for use in dogs include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/amantadine-hcl\"><span style=\"font-weight: 400;\">Amantadine<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/gabapentin\"><span style=\"font-weight: 400;\">Gabapentin<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/tramadol-hcl\"><span style=\"font-weight: 400;\">Tramadol<\/span><\/a><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Pain medications aren\u2019t the only choice for pain management in dogs. Alternative therapies for a pet\u2019s pain include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Weight loss<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low-intensity physical activity<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dietary supplements such as glucosamine-chondroitin or omega-3 fatty acids<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Physical therapy<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Surgery<\/span><\/li>\n<\/ul>\n<h2 id=\"expert-takeaway\"><span style=\"font-weight: 400;\">Expert takeaway<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">\u201cIn my experience, toxicities from ibuprofen are frequently well-meaning owners trying to relieve their pet\u2019s pain and not knowing the difference in safety of this medication between species,\u201d says <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/author\/emma-ryan\/page\/3\/\"><span style=\"font-weight: 400;\">Emma Ryan<\/span><\/a><span style=\"font-weight: 400;\">, DVM, and member of the SingleCare Medical Board. She goes on to say, \u201cUnfortunately, no safe and effective pain medication exists for dogs without a prescription, so seeking veterinary care is important if you believe your pet is in pain.\u201d<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Though safe for humans, ibuprofen (Motrin or Advil) and other human nonsteroidal anti-inflammatory (NSAID) pain relievers such as aspirin, naproxen (Aleve), or acetaminophen (Tylenol) should never be given to dogs. Even a low dose for a person (200 mg) could be toxic to a small dog.\u00a0 Ibuprofen and other over-the-counter human NSAIDS are not FDA-approved [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":627196,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[7956],"tags":[7969,808],"coauthors":[8861],"class_list":["post-627191","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pets","tag-dogs","tag-pain-management","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Can dogs take ibuprofen?<\/title>\n<meta name=\"description\" content=\"Ibuprofen is toxic to dogs. 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