{"id":627200,"date":"2024-03-06T16:57:35","date_gmt":"2024-03-06T21:57:35","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=627200"},"modified":"2025-11-07T17:32:55","modified_gmt":"2025-11-07T22:32:55","slug":"trazodone-for-cats","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/trazodone-for-cats\/","title":{"rendered":"Trazodone for cats"},"content":{"rendered":"<p><a href=\"https:\/\/www.singlecare.com\/prescription\/trazodone-hcl\"><span style=\"font-weight: 400;\">Trazodone<\/span><\/a><span style=\"font-weight: 400;\"> is a serotonin reuptake inhibitor (SARI) used to treat people with depression. In veterinary care, trazodone is commonly prescribed to treat dogs with anxiety-related behavior issues and sometimes as a sedative before vet visits. Although veterinarians sometimes use trazodone in cats, it\u2019s more widely used and well-studied in dogs.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\t\t<div id=\"coupon-cta\" class=\"coupon-cta master-template\">\n\t\t\t<p id=\"headline\">Save up to 80% on Trazodone with SingleCare<\/p>\n\t\t\t<p id=\"subheadline\">Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t<div class=\"details-wrap\">\n\t\t\t\t<div class=\"details\">\n\t\t\t\t\tTrazodone 50 mg (30 Tablet)\t\t\t\t<\/div>\n\t\t\t\t<div class=\"address\">\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"api-response\">\n\t\t\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-kroger.svg\" alt=\"Kroger Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$6.06<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/trazodone-hcl#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/trazodone-hcl#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-harristeeter.svg\" alt=\"Harris Teeter Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$6.06<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/trazodone-hcl#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/trazodone-hcl#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/trazodone-hcl#blog-cta\" class=\"coupon-see-all-btn\">See Trazodone prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t<\/span><\/p>\n<h2 id=\"what-is-trazodone-used-for-in-cats\"><span style=\"font-weight: 400;\">What is trazodone used for in cats?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Veterinarians may use trazodone to help cats relax in situations that cause situational anxiety, such as veterinary visits, hospitalization, thunderstorms, or travel. It may also be prescribed to prevent cats from being overly active while they recover from surgery. However, veterinarians are more likely to use <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/gabapentin\"><span style=\"font-weight: 400;\">gabapentin<\/span><\/a><span style=\"font-weight: 400;\"> to sedate cats since its use has been better studied than trazodone and proven effective and safe. Some veterinarians may add a trazodone dose to the gabapentin dose <\/span><a href=\"https:\/\/www.andersonmoores.com\/wp-content\/uploads\/2022\/09\/Sedation-protocols-for-cats.pdf\"><span style=\"font-weight: 400;\">in exceptional cases<\/span><\/a><span style=\"font-weight: 400;\"> where the gabapentin doesn\u2019t sufficiently calm the cat\u2019s behaviors.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/gabapentin-for-cats\/\"><b>Gabapentin for cats<\/b><\/a><\/p>\n<p><span style=\"font-weight: 400;\">For trazodone to effectively calm cats, it must be given about two hours before the cat experiences stress. For instance, if the cat needs sedation for vet visits, the pet parents should give the trazodone dose two hours before putting that cat in a carrier for transport. They will have to give their cat a tablet. If this proves too hard, the vet can provide a liquid version for easier dosing.\u00a0<\/span><\/p>\n<h3 id=\"long-term-use-of-trazodone-for-anxiety\"><span style=\"font-weight: 400;\">Long-term use of trazodone for anxiety<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Trazodone\u2019s use as a long-term anxiety medication has not been researched in cats, even though it is used in dogs as an add-on daily medication <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/dog-anxiety-medication\/\"><span style=\"font-weight: 400;\">to calm anxiety-related behavior problems<\/span><\/a><span style=\"font-weight: 400;\">, such as aggressiveness or fearfulness. For long-term use in cats, most veterinarians start with a <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/ssris\"><span style=\"font-weight: 400;\">selective serotonin reuptake inhibitor (SSRI)<\/span><\/a><span style=\"font-weight: 400;\"> like Reconcile <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/fluoxetine-hcl\/what-is\"><span style=\"font-weight: 400;\">(fluoxetine)<\/span><\/a><span style=\"font-weight: 400;\"> or a tricyclic antidepressant such as <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/amitriptyline-hcl\"><span style=\"font-weight: 400;\">amitriptyline<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/clomipramine-hcl\"><span style=\"font-weight: 400;\">clomipramine<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/imipramine-hcl\"><span style=\"font-weight: 400;\">imipramine<\/span><\/a><span style=\"font-weight: 400;\">, or <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/doxepin-hcl\"><span style=\"font-weight: 400;\">doxepin<\/span><\/a><span style=\"font-weight: 400;\">, since these drugs have dosage guidelines.\u00a0<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/trazodone-for-dogs\/\"><b>How trazodone can help anxious dogs<\/b><\/a><b>\u00a0<\/b><\/p>\n<h2 id=\"is-trazodone-safe-for-cats\"><span style=\"font-weight: 400;\">Is trazodone safe for cats?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Trazodone is not well-studied in cats. In two studies using trazodone to calm cats before and during a vet visit, trazodone doses of <\/span><a href=\"https:\/\/journals.sagepub.com\/doi\/10.1177\/1098612X15587956\"><span style=\"font-weight: 400;\">50 mg, 75 mg, and 100 mg<\/span><\/a><span style=\"font-weight: 400;\"> were effective and didn\u2019t cause any side effects that would cause worry.<\/span><\/p>\n<h3 id=\"side-effects-of-trazodone-in-cats\"><span style=\"font-weight: 400;\">Side effects of trazodone in cats<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The most common side effects of trazodone in cats are relatively mild and include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sleepiness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Poor coordination<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea, vomiting, diarrhea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Appetite changes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Agitation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Changes in behavior<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Among potential side effects, the most concerning is <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/serotonin-syndrome-treatment-and-medications\"><span style=\"font-weight: 400;\">serotonin syndrome<\/span><\/a><span style=\"font-weight: 400;\">. Serotonin is a chemical that transmits signals between nerves. Trazodone is a serotonin antagonist and reuptake inhibitor (SARI). That means the drug increases active serotonin levels at the connections between nerves throughout the central nervous system. However, medications like trazodone can overdo it sometimes, resulting in too much active serotonin at the nerve connections, resulting in a host of problems collectively called serotonin syndrome. Fortunately, it\u2019s not likely to happen if a cat or dog only takes one drug that increases serotonin, like trazodone. It\u2019s more of a risk if other serotonin-increasing drugs are taken along with trazodone.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Serotonin syndrome can be very serious and even fatal, so get emergency veterinary treatment for the cat if you notice a cluster of symptoms, including:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Vomiting<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diarrhea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Seizures<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sensitivity<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Depression<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pupil dilation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Abnormal or excessive vocalization<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Disorientation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Loss of coordination<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heightened reflexes<\/span><\/li>\n<\/ul>\n<h3 id=\"interactions-of-trazodone-with-other-pet-meds\"><span style=\"font-weight: 400;\">Interactions of trazodone with other pet meds<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Like all drugs, trazodone could cause problems when combined with other medications.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Veterinarians are most concerned about serotonin syndrome, which is typically a result of combining trazodone with other types of antidepressants. Still, anti-anxiety medications, some opioid pain relievers, and the acid reflux drug metoclopramide can cause serotonin syndrome when combined with trazodone.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Because trazodone makes a cat sleepy, veterinarians are cautious about combining it with other sedatives and <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/opioids\"><span style=\"font-weight: 400;\">narcotic pain medications<\/span><\/a><span style=\"font-weight: 400;\"> like <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/tramadol-hcl\"><span style=\"font-weight: 400;\">tramadol<\/span><\/a><span style=\"font-weight: 400;\">. However, cats may receive several sedatives when they undergo surgery or are hospitalized. That\u2019s normal, but veterinary professionals will monitor the cat.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Some drug interactions increase the risk of trazodone side effects. These include some <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/antifungals\"><span style=\"font-weight: 400;\">antifungal drugs<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/macrolides\"><span style=\"font-weight: 400;\">macrolide antibiotics<\/span><\/a><span style=\"font-weight: 400;\">, and phenothiazines (<\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/typical-antipsychotics\"><span style=\"font-weight: 400;\">a type of antipsychotic<\/span><\/a><span style=\"font-weight: 400;\">).<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Nonsteroidal anti-inflammatory drugs (<\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/nsaids\"><span style=\"font-weight: 400;\">NSAIDs<\/span><\/a><span style=\"font-weight: 400;\">) might also be a problem when combined with trazodone. Cats aren\u2019t given human NSAIDs like aspirin or ibuprofen, but they can be prescribed robenacoxib or <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/meloxicam\"><span style=\"font-weight: 400;\">meloxicam<\/span><\/a><span style=\"font-weight: 400;\"> for osteoarthritis or post-surgical pain. Trazodone could theoretically increase the risk of digestive system complications from NSAID treatment.<\/span><\/p>\n<h2 id=\"trazodone-dosage-for-cats\"><span style=\"font-weight: 400;\">Trazodone dosage for cats<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">There\u2019s no standard trazodone dosage chart for cats, although there is one <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/trazodone-for-dogs\/\"><span style=\"font-weight: 400;\">for dogs<\/span><\/a><span style=\"font-weight: 400;\">. Still, <\/span><a href=\"https:\/\/assets.ctfassets.net\/4dmg3l1sxd6g\/1ahtaRtQWXdeKJscMIueEJ\/5b2ab21afbf97601a0dd5463a82b2545\/ptb_ts_trazodone-29476-article.pdf\"><span style=\"font-weight: 400;\">Plumb\u2019s Veterinary Manual<\/span><\/a><span style=\"font-weight: 400;\"> suggests a starting dose of 25 mg for a cat that needs sedation before a veterinary visit, post-operative confinement, hospitalization, or other stressful event such as traveling. The dose may need to be increased if the cat remains too stressed.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Another suggested dosage is 10 mg per kilogram of body weight. That works out to 40\u201350 mg of trazodone for an average healthy cat.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">At least <\/span><a href=\"https:\/\/journals.sagepub.com\/doi\/10.1177\/1098612X15587956\"><span style=\"font-weight: 400;\">one study<\/span><\/a><span style=\"font-weight: 400;\"> has shown that doses of 50 mg, 75 mg, and 100 mg of trazodone can safely and effectively sedate a cat before veterinary procedures, as measured by how much the medicine reduces the cat\u2019s activity.\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/249\/2\/javma.249.2.202.xml\"><span style=\"font-weight: 400;\">Another placebo-controlled study<\/span><\/a><span style=\"font-weight: 400;\"> found that 50 mg doses were effective and safe for calming cats before a vet visit. This study, too, was limited in that only 10 cats were involved.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">To be effective, cats must be provided trazodone about two hours before the stressful event. The medicine is given orally as a tablet, but liquid versions can be prepared to make dosing easier.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">For hospitalized cats or those confined after surgery in a vet\u2019s office or animal hospital, veterinary professionals will administer trazodone doses. Trazodone is widely available as an oral tablet, and injectable versions are uncommon.\u00a0<\/span><\/p>\n<h3 id=\"can-cats-overdose-on-trazodone\"><span style=\"font-weight: 400;\">Can cats overdose on trazodone?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Trazodone overdoses have not been studied in cats, and there is no maximum trazodone dose for cats. Research has determined that doses as high as 100 mg are safe for cats.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">It\u2019s unlikely that a pet owner will give a cat too much trazodone unless they give it on their own. Currently, the only use for trazodone in cats is to sedate a cat before vet visits, so the vet will probably give owners only one or two doses.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">When a person overdoses on trazodone, the effects are generally mild, <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=4006d439-e2de-4590-82e9-fc9d56e3ec1b\"><span style=\"font-weight: 400;\">usually sleepiness and nausea<\/span><\/a><span style=\"font-weight: 400;\">. In the worst situations, <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10147490\"><span style=\"font-weight: 400;\">a trazodone overdose can throw off the heart\u2019s rhythm<\/span><\/a><span style=\"font-weight: 400;\">, sometimes badly enough to cause death. It can also slow down breathing to the point where breathing stops altogether.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If a dog is given too much trazodone, it can develop symptoms very similar to serotonin syndrome, a potentially serious side effect of drugs like trazodone. <\/span><a href=\"https:\/\/www.aspcapro.org\/resource\/understanding-trazodone-toxicosis\"><span style=\"font-weight: 400;\">Symptoms of a trazodone overdose in animals include<\/span><\/a><span style=\"font-weight: 400;\">:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Depression<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Loss of coordination<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Disorientation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hypersensitivity<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Frequent peeing<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Changes in heart rate<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Changes in blood pressure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tremors<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Seizures<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">If a cat is given too much trazodone or shows unusual symptoms after being given a dose, contact the ASPCA Animal Poison Control Center or a local emergency veterinary hospital.<\/span><\/p>\n<h3 id=\"can-i-give-my-cat-trazodone-every-day\"><span style=\"font-weight: 400;\">Can I give my cat trazodone every day?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Veterinarians usually don\u2019t prescribe daily trazodone for cats. Instead, veterinarians use trazodone in cats to calm them temporarily in extraordinary situations like a veterinary examination or travel. The cat may only need one dose or, at most, a few days of trazodone doses.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The veterinary literature only discusses trazodone dosages for short-term situational sedation. There are no dosing or monitoring protocols for treating cats with daily doses of trazodone. If a veterinarian prescribes trazodone as a daily medication, ask the veterinarian why trazodone is the best choice and if there are alternatives. Follow all the dosing instructions given by the vet.<\/span><\/p>\n<h3 id=\"how-to-give-your-cat-trazodone\"><span style=\"font-weight: 400;\">How to give your cat trazodone<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Veterinarians usually ask cat owners to give their cat a single dose of trazodone. Some situations, like travel over several days, may require a few doses.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If administering a tablet is too difficult, ask the veterinarian for an oral suspension. This could be done by the vet\u2019s office or a compounding pharmacy.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Give the trazodone dose with food at least two hours before the anticipated stressful situation, such as putting the cat in a carrier to go to the vet\u2019s. The medicine takes about two hours to reach its peak effects in a cat.<\/span><\/p>\n<h2 id=\"trazodone-alternatives-for-cats\"><span style=\"font-weight: 400;\">Trazodone alternatives for cats<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Trazodone is not the drug of choice for sedating a cat, and there are more commonly prescribed alternatives. The first-line choice is <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/gabapentin\/what-is\"><span style=\"font-weight: 400;\">gabapentin<\/span><\/a><span style=\"font-weight: 400;\"> because of its effectiveness and safety. If gabapentin is not an option, <\/span><a href=\"https:\/\/www.dvm360.com\/view\/medicine-to-ease-the-feline-mind\"><span style=\"font-weight: 400;\">other alternatives<\/span><\/a><span style=\"font-weight: 400;\"> include <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/clonidine-hcl\"><span style=\"font-weight: 400;\">clonidine<\/span><\/a><span style=\"font-weight: 400;\">, acepromazine (a tranquilizer), and <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/benzodiazepines\"><span style=\"font-weight: 400;\">benzodiazepines<\/span><\/a><span style=\"font-weight: 400;\"> such as <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/lorazepam\"><span style=\"font-weight: 400;\">lorazepam<\/span><\/a><span style=\"font-weight: 400;\"> or <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/midazolam\"><span style=\"font-weight: 400;\">midazolam<\/span><\/a><span style=\"font-weight: 400;\">. Some of these drugs are more powerful sedatives than trazodone and may be more likely to cause adverse effects.<\/span><\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/resources\/pet-meds\"><b>Save on trazodone &amp; other pet meds<\/b><\/a><\/p>\n<h2 id=\"bottom-line\"><span style=\"font-weight: 400;\">Bottom line<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Though not the drug of choice, trazodone is sometimes used to calm or sedate a cat before veterinary visits, veterinary procedures, or other anxiety-inducing situations. It works very well and has minimal side effects. Because there are risks, trazodone should only be given to a cat under the direction of a veterinary professional.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Trazodone is a serotonin reuptake inhibitor (SARI) used to treat people with depression. In veterinary care, trazodone is commonly prescribed to treat dogs with anxiety-related behavior issues and sometimes as a sedative before vet visits. Although veterinarians sometimes use trazodone in cats, it\u2019s more widely used and well-studied in dogs. What is trazodone used for [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":627202,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[7956],"tags":[9777,15095],"coauthors":[8861],"class_list":["post-627200","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pets","tag-anxiety","tag-cats","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Trazodone for cats: Dosage and safety<\/title>\n<meta name=\"description\" content=\"Trazodone is used to treat situational anxiety in cats, but usually as a second option when other methods don\u2019t work. It\u2019s more widely used in dogs.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.singlecare.com\/blog\/trazodone-for-cats\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Trazodone for cats\" \/>\n<meta property=\"og:description\" content=\"Trazodone is used to treat situational anxiety in cats, but usually as a second option when other methods don\u2019t work. It\u2019s more widely used in dogs.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.singlecare.com\/blog\/trazodone-for-cats\/\" \/>\n<meta property=\"og:site_name\" content=\"The Checkup\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/singlecare\" \/>\n<meta property=\"article:published_time\" content=\"2024-03-06T21:57:35+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-11-07T22:32:55+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2024\/03\/trazodone-for-cats.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"1080\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"SingleCare Team\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@SingleCare\" \/>\n<meta name=\"twitter:site\" content=\"@SingleCare\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"SingleCare Team\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"7 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/trazodone-for-cats\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/trazodone-for-cats\\\/\"},\"author\":{\"name\":\"SingleCare Team\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#\\\/schema\\\/person\\\/403ef50a9f402fb9ce49c429659555f5\"},\"headline\":\"Trazodone for cats\",\"datePublished\":\"2024-03-06T21:57:35+00:00\",\"dateModified\":\"2025-11-07T22:32:55+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/trazodone-for-cats\\\/\"},\"wordCount\":1516,\"publisher\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/trazodone-for-cats\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2024\\\/03\\\/trazodone-for-cats.png\",\"keywords\":[\"Anxiety\",\"Cats\"],\"articleSection\":[\"Pets\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/trazodone-for-cats\\\/\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/trazodone-for-cats\\\/\",\"name\":\"Trazodone for cats: Dosage and safety\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/trazodone-for-cats\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/trazodone-for-cats\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2024\\\/03\\\/trazodone-for-cats.png\",\"datePublished\":\"2024-03-06T21:57:35+00:00\",\"dateModified\":\"2025-11-07T22:32:55+00:00\",\"description\":\"Trazodone is used to treat situational anxiety in cats, but usually as a second option when other methods don\u2019t work. It\u2019s more widely used in dogs.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/trazodone-for-cats\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/trazodone-for-cats\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/trazodone-for-cats\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2024\\\/03\\\/trazodone-for-cats.png\",\"contentUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2024\\\/03\\\/trazodone-for-cats.png\",\"width\":1920,\"height\":1080,\"caption\":\"An orange cat looking into an Rx pill bottle: Trazodone for cats\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/trazodone-for-cats\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Trazodone for cats\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#website\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/\",\"name\":\"The Checkup, a health blog by SingleCare\",\"description\":\"Read the latest in prescription, wellness, and healthcare news\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#organization\",\"name\":\"SingleCare\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2020\\\/01\\\/placeholderimage-1.jpg\",\"contentUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2020\\\/01\\\/placeholderimage-1.jpg\",\"width\":1200,\"height\":630,\"caption\":\"SingleCare\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/singlecare\",\"https:\\\/\\\/x.com\\\/SingleCare\",\"https:\\\/\\\/www.instagram.com\\\/singlecare\\\/?hl=en\",\"https:\\\/\\\/www.linkedin.com\\\/company\\\/singlecare\\\/\",\"https:\\\/\\\/www.youtube.com\\\/channel\\\/UCd9kiPIjCQw95-2BHCYePKA\"]},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#\\\/schema\\\/person\\\/403ef50a9f402fb9ce49c429659555f5\",\"name\":\"SingleCare Team\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/7c56ea35da6164263b446caa5424dd8beeb331518803b6043b40932812936fb2?s=96&d=mm&r=gcda8e0f4c5718cb7f68c0ee812f6fafb\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/7c56ea35da6164263b446caa5424dd8beeb331518803b6043b40932812936fb2?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/7c56ea35da6164263b446caa5424dd8beeb331518803b6043b40932812936fb2?s=96&d=mm&r=g\",\"caption\":\"SingleCare Team\"},\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/author\\\/singlecareteam\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Trazodone for cats: Dosage and safety","description":"Trazodone is used to treat situational anxiety in cats, but usually as a second option when other methods don\u2019t work. It\u2019s more widely used in dogs.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.singlecare.com\/blog\/trazodone-for-cats\/","og_locale":"en_US","og_type":"article","og_title":"Trazodone for cats","og_description":"Trazodone is used to treat situational anxiety in cats, but usually as a second option when other methods don\u2019t work. It\u2019s more widely used in dogs.","og_url":"https:\/\/www.singlecare.com\/blog\/trazodone-for-cats\/","og_site_name":"The Checkup","article_publisher":"https:\/\/www.facebook.com\/singlecare","article_published_time":"2024-03-06T21:57:35+00:00","article_modified_time":"2025-11-07T22:32:55+00:00","og_image":[{"width":1920,"height":1080,"url":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2024\/03\/trazodone-for-cats.png","type":"image\/png"}],"author":"SingleCare Team","twitter_card":"summary_large_image","twitter_creator":"@SingleCare","twitter_site":"@SingleCare","twitter_misc":{"Written by":"SingleCare Team","Est. reading time":"7 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.singlecare.com\/blog\/trazodone-for-cats\/#article","isPartOf":{"@id":"https:\/\/www.singlecare.com\/blog\/trazodone-for-cats\/"},"author":{"name":"SingleCare Team","@id":"https:\/\/www.singlecare.com\/blog\/#\/schema\/person\/403ef50a9f402fb9ce49c429659555f5"},"headline":"Trazodone for cats","datePublished":"2024-03-06T21:57:35+00:00","dateModified":"2025-11-07T22:32:55+00:00","mainEntityOfPage":{"@id":"https:\/\/www.singlecare.com\/blog\/trazodone-for-cats\/"},"wordCount":1516,"publisher":{"@id":"https:\/\/www.singlecare.com\/blog\/#organization"},"image":{"@id":"https:\/\/www.singlecare.com\/blog\/trazodone-for-cats\/#primaryimage"},"thumbnailUrl":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2024\/03\/trazodone-for-cats.png","keywords":["Anxiety","Cats"],"articleSection":["Pets"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.singlecare.com\/blog\/trazodone-for-cats\/","url":"https:\/\/www.singlecare.com\/blog\/trazodone-for-cats\/","name":"Trazodone for cats: Dosage and safety","isPartOf":{"@id":"https:\/\/www.singlecare.com\/blog\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.singlecare.com\/blog\/trazodone-for-cats\/#primaryimage"},"image":{"@id":"https:\/\/www.singlecare.com\/blog\/trazodone-for-cats\/#primaryimage"},"thumbnailUrl":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2024\/03\/trazodone-for-cats.png","datePublished":"2024-03-06T21:57:35+00:00","dateModified":"2025-11-07T22:32:55+00:00","description":"Trazodone is used to treat situational anxiety in cats, but usually as a second option when other methods don\u2019t work. It\u2019s more widely used in dogs.","breadcrumb":{"@id":"https:\/\/www.singlecare.com\/blog\/trazodone-for-cats\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.singlecare.com\/blog\/trazodone-for-cats\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.singlecare.com\/blog\/trazodone-for-cats\/#primaryimage","url":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2024\/03\/trazodone-for-cats.png","contentUrl":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2024\/03\/trazodone-for-cats.png","width":1920,"height":1080,"caption":"An orange cat looking into an Rx pill bottle: Trazodone for cats"},{"@type":"BreadcrumbList","@id":"https:\/\/www.singlecare.com\/blog\/trazodone-for-cats\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.singlecare.com\/blog\/"},{"@type":"ListItem","position":2,"name":"Trazodone for cats"}]},{"@type":"WebSite","@id":"https:\/\/www.singlecare.com\/blog\/#website","url":"https:\/\/www.singlecare.com\/blog\/","name":"The Checkup, a health blog by SingleCare","description":"Read the latest in prescription, wellness, and healthcare news","publisher":{"@id":"https:\/\/www.singlecare.com\/blog\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.singlecare.com\/blog\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.singlecare.com\/blog\/#organization","name":"SingleCare","url":"https:\/\/www.singlecare.com\/blog\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.singlecare.com\/blog\/#\/schema\/logo\/image\/","url":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2020\/01\/placeholderimage-1.jpg","contentUrl":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2020\/01\/placeholderimage-1.jpg","width":1200,"height":630,"caption":"SingleCare"},"image":{"@id":"https:\/\/www.singlecare.com\/blog\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/singlecare","https:\/\/x.com\/SingleCare","https:\/\/www.instagram.com\/singlecare\/?hl=en","https:\/\/www.linkedin.com\/company\/singlecare\/","https:\/\/www.youtube.com\/channel\/UCd9kiPIjCQw95-2BHCYePKA"]},{"@type":"Person","@id":"https:\/\/www.singlecare.com\/blog\/#\/schema\/person\/403ef50a9f402fb9ce49c429659555f5","name":"SingleCare Team","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/7c56ea35da6164263b446caa5424dd8beeb331518803b6043b40932812936fb2?s=96&d=mm&r=gcda8e0f4c5718cb7f68c0ee812f6fafb","url":"https:\/\/secure.gravatar.com\/avatar\/7c56ea35da6164263b446caa5424dd8beeb331518803b6043b40932812936fb2?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/7c56ea35da6164263b446caa5424dd8beeb331518803b6043b40932812936fb2?s=96&d=mm&r=g","caption":"SingleCare Team"},"url":"https:\/\/www.singlecare.com\/blog\/author\/singlecareteam\/"}]}},"_links":{"self":[{"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/posts\/627200","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/users\/15"}],"replies":[{"embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/comments?post=627200"}],"version-history":[{"count":0,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/posts\/627200\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/media\/627202"}],"wp:attachment":[{"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/media?parent=627200"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/categories?post=627200"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/tags?post=627200"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/coauthors?post=627200"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}