{"id":627539,"date":"2024-04-03T09:30:07","date_gmt":"2024-04-03T13:30:07","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=627539"},"modified":"2025-04-09T16:48:07","modified_gmt":"2025-04-09T20:48:07","slug":"prednisone-and-caffeine","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/prednisone-and-caffeine\/","title":{"rendered":"Can you drink coffee while taking prednisone?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">If you start your day with a cup of coffee, you\u2019re in good company. The National Coffee Association reports that more Americans (up to 63%) drink coffee daily than any other beverage\u2014including water. For a good reason\u2014the caffeine it contains is good for an energy boost, and there are some notable <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/coffee-benefits\/\"><span style=\"font-weight: 400;\">health benefits<\/span><\/a><span style=\"font-weight: 400;\">. However, like most substances, there are health risks, such as anxiety and trouble sleeping, when consumed in excess. And it can interact with or worsen the side effects of certain medications, including the popular steroid <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/prednisone\"><span style=\"font-weight: 400;\">prednisone<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/prednisone\/what-is\"><span style=\"font-weight: 400;\">Prednisone<\/span><\/a><span style=\"font-weight: 400;\"> is a <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/corticosteroids\"><span style=\"font-weight: 400;\">corticosteroid<\/span><\/a><span style=\"font-weight: 400;\">\u2014just like hydrocortisone and cortisone. \u201cIt is used to control <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/inflammation\/\"><span style=\"font-weight: 400;\">inflammation<\/span><\/a><span style=\"font-weight: 400;\"> by suppressing the immune system,\u201d says Jelena Radan, Pharm.D., BCPS, Lead Clinical Pharmacy Specialist at KSP Specialty Pharmacy. Healthcare professionals prescribe this medication for treating inflammatory conditions such as <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/types-of-arthritis\/\"><span style=\"font-weight: 400;\">arthritis<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/allergy\/what-is\"><span style=\"font-weight: 400;\">allergies<\/span><\/a><span style=\"font-weight: 400;\">, inflammatory bowel disease (IBD), lung disorders, and <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/autoimmune-disease-management\/\"><span style=\"font-weight: 400;\">autoimmune diseases<\/span><\/a><span style=\"font-weight: 400;\">. It may also be used to <\/span><a href=\"https:\/\/www.kidneyfund.org\/treatments\/medicines-kidney-disease\/prednisone\"><span style=\"font-weight: 400;\">slow the progression of kidney disease<\/span><\/a><span style=\"font-weight: 400;\">. If your healthcare provider prescribes a medical treatment that includes prednisone, avoiding or limiting coffee consumption may be best, as the caffeine in coffee may worsen your medication\u2019s side effects.<\/span><\/p>\n<h2 id=\"does-coffee-interact-with-prednisone\"><span style=\"font-weight: 400;\">Does coffee interact with prednisone?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">\u201cCaffeine does not reduce the effect of prednisone in patients. Patients taking steroids can consume coffee or caffeinated products,\u201d says <\/span><a href=\"https:\/\/www.karmanos.org\/karmanos\/karmanos-physician-directory\/shao-yusra-f-11150\"><span style=\"font-weight: 400;\">Yusra Shao,<\/span><\/a><span style=\"font-weight: 400;\"> MD, a medical oncologist who works at the <\/span><a href=\"https:\/\/www.karmanos.org\/karmanos\/karmanos-home\"><span style=\"font-weight: 400;\">Barbara Ann Karmanos Cancer Institute<\/span><\/a><span style=\"font-weight: 400;\"> in Detroit, Michigan. \u201cHowever, caution may be advised when consuming both due to overlapping side effects such as <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/insomnia-treatment-and-medications\"><span style=\"font-weight: 400;\">insomnia<\/span><\/a><span style=\"font-weight: 400;\"> and <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/home-remedies-for-heartburn\/\"><span style=\"font-weight: 400;\">heartburn<\/span><\/a><span style=\"font-weight: 400;\">. Patients who experience these symptoms may benefit from minimizing their caffeine intake.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If you are taking prednisone, here are some things to keep in mind about drinking coffee with your medication:<\/span><\/p>\n<h3 id=\"it-may-have-immunosuppressing-effects\"><span style=\"font-weight: 400;\">It may have immunosuppressing effects<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Although conflicting, some studies suggest that coffee is an immunosuppressant. According to a <\/span><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S1568997217301271\"><span style=\"font-weight: 400;\">study<\/span><\/a><span style=\"font-weight: 400;\">, the beverage acts in an anti-inflammatory manner on different components of the immune system, such as natural killer (NK) cells, monocytes, and neutrophils. While there is no available study on how this effect of coffee may impact people taking immune-suppressing medications, insights suggest that coffee may amplify the immunosuppressive effects of prednisone.<\/span><\/p>\n<h3 id=\"it-may-worsen-the-side-effects-of-prednisone\"><span style=\"font-weight: 400;\">It may worsen the side effects of prednisone<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">One study showed that <\/span><a href=\"https:\/\/www.mdpi.com\/2072-6643\/12\/10\/3080\"><span style=\"font-weight: 400;\">consuming caffeine<\/span><\/a><span style=\"font-weight: 400;\">, especially in high amounts, can cause sleep disturbances and sleep disorders like insomnia, while another study indicated that <\/span><a href=\"https:\/\/www.mdpi.com\/2072-6643\/12\/8\/2259\"><span style=\"font-weight: 400;\">caffeine may play a role in migraine<\/span><\/a><span style=\"font-weight: 400;\"> headaches. Sleep disturbances and headaches are <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/prednisone-side-effects\/\"><span style=\"font-weight: 400;\">common side effects<\/span><\/a><span style=\"font-weight: 400;\"> of prednisone. It\u2019s important to keep in mind that taking this drug along with coffee may worsen these side effects.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Caffeine <\/span><a href=\"https:\/\/www.cambridge.org\/core\/journals\/nutrition-research-reviews\/article\/caffeine-and-blood-pressure-a-critical-review-perspective\/593DED6470D0EF70778667196777EAA7\"><span style=\"font-weight: 400;\">may also increase blood pressure<\/span><\/a><span style=\"font-weight: 400;\">, and an increase in blood pressure is one of the <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK534809\/\"><span style=\"font-weight: 400;\">primary adverse effects of prednisone<\/span><\/a><span style=\"font-weight: 400;\">. Other \u201ccommon side effects that a co-consumption of caffeine and prednisone can exacerbate include anxiety and an irregular heartbeat,&#8221; <\/span><a href=\"https:\/\/www.linkedin.com\/in\/jelena-radan-pharmd-bcps-13a152a6\/\"><span style=\"font-weight: 400;\">Dr. Radan<\/span><\/a><span style=\"font-weight: 400;\"> points out.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Other prednisone side effects not likely to be affected by caffeine include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Increased appetite<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Weight gain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fluid retention<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hyperglycemia (high blood sugar levels)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Allergic reactions<\/span><\/li>\n<\/ul>\n\t\t<div id=\"coupon-cta\" class=\"coupon-cta master-template\">\n\t\t\t<p id=\"headline\">Save up to 80% on Prednisone with SingleCare<\/p>\n\t\t\t<p id=\"subheadline\">Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t<div class=\"details-wrap\">\n\t\t\t\t<div class=\"details\">\n\t\t\t\t\tPrednisone 20 mg (10 Tablets)\t\t\t\t<\/div>\n\t\t\t\t<div class=\"address\">\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"api-response\">\n\t\t\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-walmart-nbh-market.svg\" alt=\"Walmart Neighborhood Market\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$3.15<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/prednisone#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/prednisone#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-walmart.svg\" alt=\"Walmart Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$3.15<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/prednisone#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/prednisone#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/prednisone#blog-cta\" class=\"coupon-see-all-btn\">See Prednisone prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n<h3 id=\"it-may-worsen-the-symptoms-of-your-medical-condition\"><span style=\"font-weight: 400;\">It may worsen the symptoms of your medical condition<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Coffee may also worsen the symptoms of certain medical conditions treated with prednisone, such as IBD. <\/span><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S088985531200074X\"><span style=\"font-weight: 400;\">Diarrhea is a hallmark symptom<\/span><\/a><span style=\"font-weight: 400;\">, and some available evidence suggests coffee may have significant effects on digestive function, including laxative effects. For instance, a <\/span><a href=\"https:\/\/www.mdpi.com\/2072-6643\/14\/2\/399\"><span style=\"font-weight: 400;\">review of studies<\/span><\/a><span style=\"font-weight: 400;\"> indicates that both regular and decaffeinated coffee may stimulate and increase the movement of bowel content through the large intestine, thereby facilitating the emptying of the bowels. This means consuming coffee while taking prednisone for IBD may worsen symptoms like <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/diarrhea-treatment-and-medications\"><span style=\"font-weight: 400;\">diarrhea<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Decaffeinated coffee is a safer option for people on medication since it contains little to no caffeine, the major controversial ingredient in coffee. However, it still contains other ingredients that may interact with your medication or its effects. For instance, similar to regular coffee, decaffeinated coffee may also <\/span><a href=\"https:\/\/www.mdpi.com\/2072-6643\/14\/2\/399\"><span style=\"font-weight: 400;\">have stimulatory effects on colon bowel movement<\/span><\/a><span style=\"font-weight: 400;\">, indicating that caffeine is not the causative ingredient in this case.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/coffee-for-constipation\/\"><b>Is coffee good for constipation?<\/b><\/a><\/p>\n<h3 id=\"it-may-help-with-inflammation\"><span style=\"font-weight: 400;\">It may help with inflammation<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">A <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28967799\/\"><span style=\"font-weight: 400;\">review of 15 studies<\/span><\/a><span style=\"font-weight: 400;\"> suggests that coffee consumption is associated with anti-inflammatory action. However, this does not mean you have the green light for unlimited coffee consumption if you have an inflammatory condition. The effect of coffee on inflammation depends on genetics and other individual differences. A study published in<\/span><i><span style=\"font-weight: 400;\"> Molecular Nutrition and Food Research<\/span><\/i><span style=\"font-weight: 400;\"> observed <\/span><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mnfr.201600328\"><span style=\"font-weight: 400;\">contradictory effects of coffee<\/span><\/a><span style=\"font-weight: 400;\"> on inflammation, with the beverage causing a significant pro-inflammatory impact on the study participants.<\/span><\/p>\n<h2 id=\"best-practices-for-taking-prednisone\"><span style=\"font-weight: 400;\">Best practices for taking prednisone\u00a0<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">To ensure you are taking prednisone safely and to maximize its effects, here are some general helpful practices you may want to adopt:<\/span><b><\/b><\/p>\n<ul>\n<li><b>Take the medication with food. <\/b><span style=\"font-weight: 400;\">This <\/span><a href=\"https:\/\/www.nhs.uk\/medicines\/prednisolone\/how-and-when-to-take-prednisolone-tablets-and-liquid\/\"><span style=\"font-weight: 400;\">can reduce stomach upset<\/span><\/a><span style=\"font-weight: 400;\"> unless your medication is labeled &#8220;enteric coated&#8221; or &#8220;gastro-resistant.&#8221; These may be taken without food.\u00a0<\/span><\/li>\n<li><b>Take it in the morning.<\/b><span style=\"font-weight: 400;\"> If your prednisone dosage is once daily, consider taking the pills in the morning to reduce its likelihood of affecting your sleep. If your dosage is twice daily, take the second dose for the day no later than mid-afternoon.<\/span><\/li>\n<li><b>Swallow the pill whole.<\/b><span style=\"font-weight: 400;\"> Prednisone in tablet form is <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK534809\/\"><span style=\"font-weight: 400;\">best ingested whole<\/span><\/a><span style=\"font-weight: 400;\"> without crushing, breaking, chewing, or dividing it. Solutions are available for those unable to take pills.<\/span><\/li>\n<li><b>Avoid taking certain medications with prednisone.<\/b><span style=\"font-weight: 400;\"> Tell your healthcare provider if you are taking medicines like diuretics (water pills), <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/nsaids\"><span style=\"font-weight: 400;\">non-steroidal anti-inflammatory drugs (NSAIDs)<\/span><\/a><span style=\"font-weight: 400;\">, estrogen pills (including <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/best-birth-control-pill-contraceptive-guide\/\"><span style=\"font-weight: 400;\">birth control pills<\/span><\/a><span style=\"font-weight: 400;\">), blood thinners (such as <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/warfarin-sodium\/what-is\"><span style=\"font-weight: 400;\">warfarin<\/span><\/a><span style=\"font-weight: 400;\">), and diabetes medications. These medications may interfere with prednisone.<\/span><\/li>\n<li><b>Protect yourself against infections by adopting good hygiene practices.<\/b><span style=\"font-weight: 400;\"> Prednisone can make you <\/span><a href=\"https:\/\/www.nhs.uk\/medicines\/prednisolone\/about-prednisolone-tablets-and-liquid\/\"><span style=\"font-weight: 400;\">vulnerable to infections<\/span><\/a><span style=\"font-weight: 400;\"> like COVID-19. Keep up-to-date on vaccines as recommended by your provider.<\/span><\/li>\n<li><b>Do not stop your prednisone therapy suddenly. <\/b><span style=\"font-weight: 400;\">This can cause <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/prednisone-withdrawal\/\"><span style=\"font-weight: 400;\">withdrawal symptoms<\/span><\/a><span style=\"font-weight: 400;\">, especially if you are taking a high dose. Your healthcare provider can guide you on how to quit taking prednisone medication safely.<\/span><\/li>\n<li><b>Do not take prednisone with certain supplements. <\/b><span style=\"font-weight: 400;\">Herbal supplements are not regulated by the FDA, so the full extent of interactions with drugs like prednisone is unknown. On the other hand, long-term prednisone consumption can reduce calcium absorption and activation of vitamin D to aid in calcium absorption; therefore, you may be told to <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7046131\/\"><span style=\"font-weight: 400;\">take calcium and vitamin D supplements<\/span><\/a><span style=\"font-weight: 400;\"> while taking steroids.<\/span><\/li>\n<li><b>Avoid foods with a high amount of salt or sugar.<\/b><span style=\"font-weight: 400;\"> Since high blood sugar (hyperglycemia) and high blood pressure (hypertension) are side effects of prednisone, it makes sense to <\/span><a href=\"https:\/\/www.kidney.org\/content\/what-you-need-know-about-prednisone\"><span style=\"font-weight: 400;\">limit your intake of foods with high amounts<\/span><\/a><span style=\"font-weight: 400;\"> of refined sugar and salt, which can contribute to hyperglycemia and hypertension, respectively.<\/span><\/li>\n<\/ul>\n<p><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/prednisone\"><span style=\"font-weight: 400;\">Prednisone coupons<\/span><\/a><\/p>\n<h2 id=\"bottom-line-drinking-coffee-with-prednisone-is-low-risk\"><span style=\"font-weight: 400;\">Bottom line: Drinking coffee with prednisone is low risk<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Coffee is safe to consume in moderate amounts while taking prednisone, though there are some potential risks, including immune suppression, increased side effects, or worsened symptoms. If you are a coffee lover, cutting it out entirely may be difficult. Instead, try drinking less coffee and ensuring you don\u2019t take it close to your medication time to minimize potential risks. Always consult your healthcare provider for medical advice about drug interactions and other possible side effects<\/span><span style=\"font-weight: 400;\">.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>If you start your day with a cup of coffee, you\u2019re in good company. The National Coffee Association reports that more Americans (up to 63%) drink coffee daily than any other beverage\u2014including water. For a good reason\u2014the caffeine it contains is good for an energy boost, and there are some notable health benefits. However, like [&hellip;]<\/p>\n","protected":false},"author":135,"featured_media":627201,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[814,20955,8905],"coauthors":[20970],"class_list":["post-627539","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-drug-interactions","tag-inflammation","tag-seasonal","franchise-the-jolt","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.8 (Yoast SEO v27.8) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Can you drink coffee while taking prednisone?<\/title>\n<meta name=\"description\" content=\"Although it\u2019s generally safe to drink coffee with prednisone, it can increase the risk of side effects. 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