{"id":627805,"date":"2024-04-15T11:59:04","date_gmt":"2024-04-15T15:59:04","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=627805"},"modified":"2026-04-17T11:21:10","modified_gmt":"2026-04-17T15:21:10","slug":"take-claritin-and-zyrtec-together","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/take-claritin-and-zyrtec-together\/","title":{"rendered":"Can you take Claritin and Zyrtec together?"},"content":{"rendered":"<p><a href=\"https:\/\/www.singlecare.com\/prescription\/claritin\/what-is\"><span style=\"font-weight: 400;\">Claritin<\/span><\/a><span style=\"font-weight: 400;\"> (generic name loratadine) and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/zyrtec-allergy\/what-is\"><span style=\"font-weight: 400;\">Zyrtec<\/span><\/a><span style=\"font-weight: 400;\"> (generic name cetirizine) are both over-the-counter (OTC) medicines commonly taken to treat allergy symptoms of hay fever, also known as seasonal allergies and hives (urticaria). They both temporarily relieve itchy and watery eyes, runny nose (allergic rhinitis), sneezing, and itching of the nose or throat. Antihistamines work by reducing the production of a natural substance in the body called histamine, which is responsible for causing allergic reactions when the body is exposed to allergens, such as pollen.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Both Claritin and Zyrtec, along with <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/allegra-allergy\/what-is\"><span style=\"font-weight: 400;\">Allegra<\/span><\/a><span style=\"font-weight: 400;\"> (fexofenadine) and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/xyzal-allergy-24hr\/what-is\"><span style=\"font-weight: 400;\">Xyzal<\/span><\/a><span style=\"font-weight: 400;\"> (cetirizine), are classified as second-generation antihistamines. Notably, these newer antihistamines cause fewer central nervous system (CNS) side effects, such as drowsiness and sedation, compared to allergy medications known as first-generation antihistamines, such as <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/benadryl-allergy\/what-is\"><span style=\"font-weight: 400;\">Benadryl<\/span><\/a><span style=\"font-weight: 400;\"> (diphenhydramine).<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\t\t<div id=\"coupon-cta\" class=\"coupon-cta master-template\">\n\t\t\t<p id=\"headline\">Save up to 80% on Claritin with SingleCare<\/p>\n\t\t\t<p id=\"subheadline\">Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t<div class=\"details-wrap\">\n\t\t\t\t<div class=\"details\">\n\t\t\t\t\tClaritin 10 mg (30 Tablet)\t\t\t\t<\/div>\n\t\t\t\t<div class=\"address\">\n\t\t\t\t\t23663 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"api-response\">\n\t\t\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-food-lion.svg\" alt=\"Food Lion\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$9.43<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/claritin#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/claritin#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-kroger.svg\" alt=\"Kroger Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$9.46<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/claritin#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/claritin#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/claritin#blog-cta\" class=\"coupon-see-all-btn\">See Claritin prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t<\/span><\/p>\n<h2 id=\"can-you-take-claritin-and-zyrtec-together\"><span style=\"font-weight: 400;\">Can you take Claritin and Zyrtec together?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Although Claritin and Zyrtec are chemically different antihistamines, they are in the same drug class and share a similar blocking action on the histamine receptors. Because of these similar mechanisms of action, it is not recommended that they be taken together other than on direct medical advice from a healthcare provider.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">High doses of antihistamines beyond the recommended dose are not likely to provide better relief of allergic symptoms but may increase the risk of undesirable, particularly sedating, side effects. Other potential side effects of <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2000\/20641s7lbl.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Claritin<\/span><\/a><span style=\"font-weight: 400;\"> and <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2002\/19835s15,%2020346s8lbl.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Zyrtec<\/span><\/a><span style=\"font-weight: 400;\">, alone or combined, include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fatigue<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dry mouth<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Headache<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stomach pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nervousness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diarrhea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Constipation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cough<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dry eyes<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Serious side effects that may require immediate medical attention may include:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Abnormal heart rate<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Palpitations<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Blood pressure disturbances<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Severe faintness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Confusion<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hypersensitivity (allergic) reaction to inactive or active ingredients<\/span><\/li>\n<\/ul>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/zyrtec-and-blood-pressure\/\"><b>Does Zyrtec raise blood pressure?<\/b><\/a><\/p>\n<p><span style=\"font-weight: 400;\">Although it is not recommended to take Claritin and Zyrtec together or on the same day, there are other allergy medicine combinations that can provide greater allergy relief. An antihistamine combined with a decongestant, such as pseudoephedrine (the active ingredient in <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/sudafed-sinus-congestion-24hr\/what-is\"><span style=\"font-weight: 400;\">Sudafed<\/span><\/a><span style=\"font-weight: 400;\">), provides additional help with nasal congestion and sinus pressure. Both Claritin and Zyrtec come in a combination form that includes pseudoephedrine under the brand names <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/claritin-d-24-hour\/what-is\"><span style=\"font-weight: 400;\">Claritin-D<\/span><\/a><span style=\"font-weight: 400;\"> and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/zyrtec-d-allergy-congestion\/what-is\"><span style=\"font-weight: 400;\">Zyrtec-D<\/span><\/a><span style=\"font-weight: 400;\">. Another combination of allergy medicines to consider would be Claritin or Zyrtec with a steroid nasal spray, such as <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/flonase-allergy-relief\/what-is\"><span style=\"font-weight: 400;\">Flonase<\/span><\/a><span style=\"font-weight: 400;\"> (fluticasone). This combination may be appropriate for some allergy sufferers depending on the clinical symptoms and the response to treatment.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\t\t<div class=\"singlecare-dynamic-newsletter-wrapper sin-newsletter-wrapper\">\n\t\t\t<span class=\"heading\">Get our allergies newsletter<\/span>\n\t\t\t<form class=\"form-wrapper\" data-newsletter-form=\"1\" data-subsource=\"Allergies Newsletter\">\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<label for=\"dynamic-email\">Email<\/label>\n\t\t\t\t\t<input type=\"email\" id=\"dynamic-email\" class=\"email\" required>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<input class=\"submit-form-btn\" type=\"submit\" value=\"Click to sign up\">\n\t\t\t\t<\/div>\n\t\t\t<\/form>\n\t\t\t<p class=\"success-message\" aria-live=\"polite\"><\/p>\n\t\t<\/div>\n\t<\/span><\/p>\n<h2 id=\"what-are-the-drug-interactions-between-claritin-and-zyrtec\"><span style=\"font-weight: 400;\">What are the drug interactions between Claritin and Zyrtec?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">It is important to note that, while there have been no drug interactions reported, taking Claritin and Zyrtec together or within the same 24-hour period may result in an increased likelihood of adverse events without the benefit of increased symptom relief.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\t\t<div id=\"coupon-cta\" class=\"coupon-cta master-template\">\n\t\t\t<p id=\"headline\">Save up to 80% on Zyrtec with SingleCare<\/p>\n\t\t\t<p id=\"subheadline\">Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t<div class=\"details-wrap\">\n\t\t\t\t<div class=\"details\">\n\t\t\t\t\tZyrtec 10 mg, 100 tablets (1 Bottle)\t\t\t\t<\/div>\n\t\t\t\t<div class=\"address\">\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"api-response\">\n\t\t\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-kroger.svg\" alt=\"Kroger Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$9.34<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/zyrtec-allergy#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/zyrtec-allergy#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-harristeeter.svg\" alt=\"Harris Teeter Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$9.34<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/zyrtec-allergy#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/zyrtec-allergy#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/zyrtec-allergy#blog-cta\" class=\"coupon-see-all-btn\">See Zyrtec prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t<\/span><\/p>\n<h2 id=\"how-long-after-taking-claritin-can-i-take-zyrtec\"><span style=\"font-weight: 400;\">How long after taking Claritin can I take Zyrtec?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Zyrtec is only available as an extended dosage form that is effective for 24 hours. Therefore, it is not recommended to take both Claritin and Zyrtec within the same 24-hour period. When switching from one allergy med to the other, wait at least 24 hours after taking Zyrtec, at least 12 hours when taking the 12-hour dosage form of Claritin, or 24 hours when taking the 24-hour dosage form of Claritin.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Because both are considered less sedating, Claritin and Zyrtec can be taken at any time of the day, including in the morning. Some may experience drowsiness with one or both products, so for those people, it may be best to take their dose in the evening.\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Claritin (generic name loratadine) and Zyrtec (generic name cetirizine) are both over-the-counter (OTC) medicines commonly taken to treat allergy symptoms of hay fever, also known as seasonal allergies and hives (urticaria). They both temporarily relieve itchy and watery eyes, runny nose (allergic rhinitis), sneezing, and itching of the nose or throat. Antihistamines work by reducing [&hellip;]<\/p>\n","protected":false},"author":133,"featured_media":627806,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[554,10708],"coauthors":[20733],"class_list":["post-627805","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-allergies","tag-over-the-counter-medications","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Can you take Claritin and Zyrtec together? | SingleCare<\/title>\n<meta name=\"description\" content=\"Claritin and Zyrtec belong to the same drug class. 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They should not be taken together because of their similar mechanisms of action. 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