{"id":628079,"date":"2024-05-07T14:26:41","date_gmt":"2024-05-07T18:26:41","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=628079"},"modified":"2024-10-25T09:58:27","modified_gmt":"2024-10-25T13:58:27","slug":"what-happens-if-you-take-jardiance-at-night","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/what-happens-if-you-take-jardiance-at-night\/","title":{"rendered":"What happens if you take Jardiance at night?"},"content":{"rendered":"

Jardiance, known generically as empagliflozin, is an oral medication often prescribed to manage blood sugar levels in people with Type 2 diabetes. It works as a <\/span>sodium-glucose cotransporter 2 (SGLT2) inhibitor<\/span><\/a> that helps the kidneys remove blood sugar or glucose from the bloodstream through the urine. It’s typically recommended to take Jardiance in the morning.<\/span><\/p>\n

If you take Jardiance at night, it could cause you to wake frequently to urinate. As a result, Jardiance might also disrupt your sleep patterns. Some studies suggest that the timing of Jardiance doses may also affect the drug’s metabolism, with the effects of Jardiance on blood sugar levels varying between morning and evening doses. <\/span><\/p>\n

Read on to learn more about what happens if you take Jardiance at night.<\/span><\/p>\n

The circadian rhythm and timing of medications<\/b><\/h2>\n

The field of chronopharmacology explores how our body’s internal clock, known as its <\/span>circadian rhythm<\/span><\/a>, affects the effectiveness and safety of medications. This rhythm regulates various bodily functions, including blood pressure and blood sugar levels. Medications can have different effects depending on the time they are taken, as our bodies respond differently to treatment throughout the day.<\/span><\/p>\n

The body’s circadian rhythm also <\/span>affects how the kidneys work<\/span><\/a>. The kidneys have different functions, such as filtering the blood and helping control blood pressure. This natural rhythm guides when these functions are most active or slow. Understanding this timing can help healthcare providers choose the best times to give medications for better results in treating kidney-related issues.<\/span><\/p>\n

Researchers are studying how the timing of Jardiance aligns with our biological clock, especially as it relates to <\/span>managing blood sugar levels<\/span><\/a>. By considering the natural fluctuations in our body’s functions throughout the day, healthcare providers may be able to personalize treatment plans for better outcomes.<\/span><\/p>\n

How is Jardiance administered?<\/b><\/h2>\n

Jardiance is a brand-name drug available as oral tablets in strengths of <\/a><\/span>10 and 25 milligrams (<\/span>mg<\/span>). People typically take Jardiance once daily in the morning, with or without food. Taking it at the same time every day may help maintain a consistent level of the medication in the bloodstream.<\/span><\/p>\n

The typical starting dose of Jardiance is 10 mg, which healthcare providers may increase to 25 mg based on how well a patient’s blood sugar levels are controlled and their overall tolerance to the medication. As it works in the kidneys, it’s recommended to have kidney function assessed before taking the drug. Like all medications, following the prescribed dosing instructions is important to ensure the best results.<\/span><\/p>\n

This diabetes medication is recommended to be taken along with diet and exercise to lower blood sugar levels. Although it’s mainly prescribed for diabetes, it can also help reduce the risk of death from <\/span>heart failure<\/span><\/a> or heart disease. It has also been approved to reduce the risk of worsening kidney function that could lead to hospital visits or death in people with chronic kidney disease. <\/span><\/p>\n

What happens when you take Jardiance at night?<\/b><\/h2>\n

While Jardiance is generally recommended in the morning, taking it in the evening could still help manage blood sugar levels. Recent studies suggest that the timing of the dose does not significantly alter the efficacy of Jardiance.<\/span><\/p>\n

Studies on the effects of Jardiance at night<\/b><\/h2>\n

The recommendation to take Jardiance in the morning comes from its drug label and is based on clinical research about the drug’s peak action times and its potential effects on the circadian rhythm. Taking this medication in the morning may be beneficial because <\/span>blood sugar levels tend to rise early in the day<\/span><\/a>.<\/span><\/p>\n

A <\/span>recent study<\/span><\/a> looked at the effects of taking Jardiance in the evening versus the morning in healthy adults. The study found that after taking a single 10 mg dose of Jardiance, the time it took for the medication to reach its peak concentration (T max) was slightly shorter in the morning compared to the evening. <\/span><\/p>\n

Interestingly, the total exposure of the drug measured through AUC (area under the curve) was slightly higher for the evening dose than for the morning dose. In other words, there were differences in how the body processed the medication depending on the time it was given. <\/span><\/p>\n

The study also looked at the amount of blood sugar excreted in urine (UGE) over 24 hours after taking Jardiance. Surprisingly, the study found that more blood sugar was excreted after the evening dose than after the morning dose. However, despite these differences between evening and morning doses, the study concluded that there was no significant statistical difference in the effects of Jardiance when taken at night versus in the morning. <\/span><\/p>\n

It’s important to follow the advice of a healthcare provider since factors like kidney function, blood sugar levels, and other medications can affect the timing.<\/span><\/p>\n

Potential side effects during sleep<\/b><\/h3>\n

Jardiance works to lower blood sugar the same way at nighttime as it does in the morning. However, there may still be <\/span>side effects<\/span><\/a> associated with taking it at night. For example, taking Jardiance at night may increase the risk of nocturnal hypoglycemia (low blood sugar during sleep), especially if it’s taken with other glucose-lowering medications such as insulin.<\/span><\/p>\n

Symptoms of low blood sugar<\/span><\/a> to be aware of include:<\/span><\/p>\n