{"id":628104,"date":"2024-05-09T14:12:51","date_gmt":"2024-05-09T18:12:51","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=628104"},"modified":"2024-10-25T09:58:05","modified_gmt":"2024-10-25T13:58:05","slug":"armour-thyroid-vs-synthroid","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/armour-thyroid-vs-synthroid\/","title":{"rendered":"Armour Thyroid vs. Synthroid: Differences, similarities &#038; side effects"},"content":{"rendered":"<p><span style=\"font-weight: 400;\"><a href=\"#key-differences\">Key differences<\/a>&#9474;<a href=\"#conditions\">Conditions treated<\/a>&#9474;<a href=\"#insurance\">Insurance and cost<\/a>&#9474;<a href=\"#side-effects\">Side effects<\/a>&#9474;<a href=\"#warnings\">Warnings<\/a>&#9474;<a href=\"#bottom-line\">Bottom line<\/a><\/span><\/p>\n<p><span style=\"font-weight: 400;\">Armour Thyroid and Synthroid are both brand-name medications used to treat an underactive thyroid gland (hypothyroidism). They are part of the <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/thyroid-hormones\"><span style=\"font-weight: 400;\">thyroid hormone<\/span><\/a><span style=\"font-weight: 400;\"> drug class and work by supplementing thyroid hormones that are usually produced by the body. While both medications are known as thyroid agents, they have notable differences in chemical makeup and price.<\/span><\/p>\n<h2 id=\"armour-thyroid-vs-synthroid-key-differences\"><span style=\"font-weight: 400;\">Armour Thyroid vs. Synthroid: Key differences<\/span><\/h2>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/armour-thyroid\"><span style=\"font-weight: 400;\">Armour Thyroid<\/span><\/a><span style=\"font-weight: 400;\"> and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/synthroid\"><span style=\"font-weight: 400;\">Synthroid<\/span><\/a><span style=\"font-weight: 400;\"> are both thyroid hormone replacement medications, but they are biochemically different.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Amy Offutt, MD, <\/span><span style=\"font-weight: 400;\">president of the <\/span><a href=\"https:\/\/www.ilads.org\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">International Lyme and Associated Diseases Society (ILADS<\/span><span style=\"font-weight: 400;\">)<\/span><\/a><span style=\"font-weight: 400;\">,<\/span> <span style=\"font-weight: 400;\">and <\/span><a href=\"https:\/\/www.digestivereset.com\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Inna Melamed, Pharm.D.<\/span><\/a><span style=\"font-weight: 400;\">, a functional medicine practitioner and author of <\/span><i><span style=\"font-weight: 400;\">Digestive Reset<\/span><\/i><span style=\"font-weight: 400;\">, both sum up the differences:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Armour Thyroid is a dried, animal-derived thyroid hormone (from pig thyroid glands), while Synthroid is a synthetic thyroid (synthetic T).<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Armour Thyroid contains triiodothyronine (T3) and thyroxine (T4), while Synthroid contains only T4.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Armour Thyroid is only available as a brand-name drug, while Synthroid is just one brand-name version of the generic drug levothyroxine.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">In addition to biochemical differences, Armour Thyroid costs more than Synthroid and tends to cause more side effects, according to Dr. Offutt. Dosing also differs dramatically between Armour Thyroid and Synthroid. Armour Thyroid is <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/armour-thyroid\/what-is#dosage\"><span style=\"font-weight: 400;\">dosed in milligrams<\/span><\/a><span style=\"font-weight: 400;\">, which are thousandths of grams. Synthroid is <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/synthroid\/what-is#dosage\"><span style=\"font-weight: 400;\">dosed in micrograms<\/span><\/a><span style=\"font-weight: 400;\">, which are millionths of grams.&nbsp;<\/span><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h3 id=\"compare-key-differences-armour-thyroid-vs-synthroid\"><span class=\"title\">Compare key differences: Armour thyroid vs. Synthroid<br \/>\n<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><\/td>\n<td><strong>Armour Thyroid&nbsp;<\/strong><\/td>\n<td><strong>Synthroid<\/strong><\/td>\n<\/tr>\n<tr>\n<td><b>Drug class<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Thyroid hormone<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Thyroid hormone<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Brand\/generic status<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Brand<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Brand<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>What is the generic name?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">N\/A<\/span><\/td>\n<td><span style=\"font-weight: 400;\"> Levothyroxine<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>What form(s) does the drug come in?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Oral tablet<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Oral tablet<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>What is the standard dosage?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">30&ndash;120 mg once per day<\/span><\/td>\n<td><span style=\"font-weight: 400;\">25&ndash;200 mcg once per day<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>How long is the typical treatment?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Indefinite; long-term<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Indefinite; long-term<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Who typically uses the medication?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Adults with hypothyroidism<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Adults with hypothyroidism<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"armour-thyroid-vs-synthroid-conditions-treated\"><span style=\"font-weight: 400;\">Armour Thyroid vs. Synthroid: Conditions treated<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Both Armour Thyroid and Synthroid are used to treat underactive thyroid, medically known as hypothyroidism. &ldquo;Any patient who needs thyroid replacement hormone (because the thyroid is not secreting enough hormone naturally) can potentially benefit from Armour Thyroid or Synthroid,&rdquo; Dr. Offutt says.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Armour Thyroid and Synthroid are used for hypothyroidism of all types:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Primary hypothyroidism: When the thyroid gland itself does not secrete enough hormone<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.uclahealth.org\/medical-services\/surgery\/endocrine-surgery\/patient-resources\/patient-education\/endocrine-surgery-encyclopedia\/hypothyroidism-secondary#:~:text=Definition,failure%20of%20the%20pituitary%20gland.\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Secondary hypothyroidism<\/span><\/a><span style=\"font-weight: 400;\">: When problems with the pituitary gland decrease thyroid activity<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK519536\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Tertiary hypothyroidism<\/span><\/a><span style=\"font-weight: 400;\">: When disorders of the hypothalamus result in reduced thyroid activity<\/span><\/li>\n<\/ul>\n<h3 id=\"armour-thyroid-vs-synthroid-for-hashimotos\"><span style=\"font-weight: 400;\">Armour Thyroid vs. Synthroid for Hashimoto&#8217;s&nbsp;&nbsp;<\/span><\/h3>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK459262\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Hashimoto thyroiditis<\/span><\/a><span style=\"font-weight: 400;\"> is an autoimmune disease in which the body attacks its <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/tag\/thyroid\/\"><span style=\"font-weight: 400;\">thyroid cells<\/span><\/a><span style=\"font-weight: 400;\">. This destruction of thyroid cells causes hypothyroidism.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">&#8220;Either of these medications may be used to treat patients with hypothyroidism secondary to Hashimoto thyroiditis,&#8221; Dr. Offutt says. However, Dr. Melamed notes that the American Thyroid Association and other international organizations recommend Synthroid as the most effective option for Hashimoto&#8217;s-related hypothyroidism.<\/span><\/p>\n<p>&nbsp;<\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h3 id=\"compare-conditions-treated-armour-thyroid-vs-synthroid\"><span class=\"title\">Compare conditions treated: Armour Thyroid vs. Synthroid<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><b>Condition<\/b><\/td>\n<td><b>Armour Thyroid<\/b><\/td>\n<td><b>Synthroid<\/b><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Primary (thyroidal) hypothyroidism<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Secondary (pituitary) hypothyroidism<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Tertiary (hypothalamic) hypothyroidism<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Hashimoto&rsquo;s thyroiditis<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<h2 id=\"is-armour-thyroid-better-than-synthroid\"><span style=\"font-weight: 400;\">Is Armour Thyroid better than Synthroid?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Both Armour Thyroid and Synthroid are effective thyroid medications. They both replace thyroid hormones in patients whose thyroids <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/thyroid-issue-symptoms\"><span style=\"font-weight: 400;\">do not secrete enough hormones naturally<\/span><\/a><span style=\"font-weight: 400;\">. Though Synthroid only has the T4 component of thyroid hormone, Dr. Offutt says it is believed that humans can convert some T4 to T3 after ingesting it. So, while Armour Thyroid offers a more complete hormone replacement, it is not always better.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">&ldquo;The current conventional prescribing approach tends to be the prescription of levothyroxine (Synthroid),&rdquo; Dr. Offutt says. However, she emphasizes the importance of a personalized approach and says that some patients may experience more improvement of symptoms with a T4 or T3 product like Armour Thyroid.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In one retrospective study of 250 hypothyroid patients published in the <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8089975\/\" target=\"_blank\" rel=\"noopener\"><i><span style=\"font-weight: 400;\">Journal of the Endocrine Society<\/span><\/i><\/a><span style=\"font-weight: 400;\">, researchers found that patients tend to feel better when taking Armour Thyroid than when taking levothyroxine, but they also have a higher risk of adverse effects with Armour Thyroid than with levothyroxine.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Ultimately, the most effective medication should be determined by a healthcare provider who has a complete picture of your medical condition, history, and other medications that you&rsquo;re taking in order to see if they interact with Armour Thyroid or Synthroid.<\/span><\/p>\n<h2 id=\"armour-thyroid-vs-synthroid-insurance-coverage-and-cost-comparison\"><span style=\"font-weight: 400;\">Armour Thyroid vs. Synthroid: Insurance coverage and cost comparison<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Without insurance, Armour Thyroid costs about $55 for 30, 60 mg tablets, while Synthroid costs about $76 for 30, 100 mcg tablets. However, drug prices vary widely. It&rsquo;s a good idea to check with your insurance company or Medicare Part D plan for information that is accurate for your situation.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">SingleCare coupons can help you save on <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/armour-thyroid#coupon-prices\"><span style=\"font-weight: 400;\">Armour Thyroid<\/span><\/a><span style=\"font-weight: 400;\">, bringing the cost down to about $28 for 30, 60 mg tablets. You can also save on <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/synthroid#coupon-prices\"><span style=\"font-weight: 400;\">Synthroid<\/span><\/a><span style=\"font-weight: 400;\">, paying about $50 for 30, 50 mcg tablets.<\/span><\/p>\n<p>&nbsp;<\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h3 id=\"compare-cost-coverage-armour-thyroid-vs-synthroid\"><span class=\"title\">Compare cost &amp; coverage: Armour Thyroid vs. Synthroid&nbsp;<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><\/td>\n<td><b>Armour Thyroid<\/b><\/td>\n<td><b>Synthroid<\/b><\/td>\n<\/tr>\n<tr>\n<td><b>Typically covered by insurance?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">In most cases, no<\/span><\/td>\n<td><span style=\"font-weight: 400;\">In most cases, yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Typically covered by Medicare Part D?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">In most cases, yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Quantity<\/b><\/td>\n<td><span style=\"font-weight: 400;\">30, 60 mg tablets&nbsp;<\/span><\/td>\n<td><span style=\"font-weight: 400;\">30, 50 mcg tablets<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>SingleCare cost<\/b><\/td>\n<td><span style=\"font-weight: 400;\">$28<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$50<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<h2 id=\"armour-thyroid-vs-synthroid-side-effects\"><span style=\"font-weight: 400;\">Armour Thyroid vs. Synthroid side effects<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Adverse reactions of both Armour Thyroid and Synthroid tend to be <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/thyroid-issue-symptoms\"><span style=\"font-weight: 400;\">symptoms of thyroid problems<\/span><\/a><span style=\"font-weight: 400;\"> rather than drug side effects. In other words, a person taking these drugs might experience symptoms of hyperthyroidism (if their dose is too high) or hypothyroidism (if their dose is too low).&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Common symptoms of imbalanced thyroid hormone include weight changes, hair loss, fast heart rate, and excessive sweating or nervousness. Side effects of <\/span><a href=\"https:\/\/www.mayoclinic.org\/drugs-supplements\/levothyroxine-oral-route\/side-effects\/drg-20072133\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Synthroid<\/span><\/a><span style=\"font-weight: 400;\"> and <\/span><a href=\"https:\/\/www.mayoclinic.org\/drugs-supplements\/thyroid-oral-route\/side-effects\/drg-20069086?p=1\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Armour Thyroid<\/span><\/a><span style=\"font-weight: 400;\"> are somewhat similar, with the exception of fatigue. In fact, 40.8% of patients in the study published by the <\/span><i><span style=\"font-weight: 400;\">Journal of the Endocrine Society <\/span><\/i><span style=\"font-weight: 400;\">switched from levothyroxine to Armour Thyroid because of the fatigue they experienced on levothyroxine.<\/span><\/p>\n<p>&nbsp;<\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h3 id=\"compare-side-effects-armour-thyroid-vs-synthroid\"><span class=\"title\">Compare side effects: Armour Thyroid vs. Synthroid&nbsp;<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><\/td>\n<td><b>Armour Thyroid<\/b><\/td>\n<td><b>Synthroid<\/b><\/td>\n<\/tr>\n<tr>\n<td><b>Side effect<\/b><\/td>\n<td><b>Applicable?<\/b><\/td>\n<td><b>Applicable?<\/b><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Appetite changes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/blog\/tag\/weight-loss\/\"><span style=\"font-weight: 400;\">Weight loss<\/span><\/a><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Heat intolerance<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Excessive sweating<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Headache&nbsp;<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Hyperactivity or nervousness<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/conditions\/hair-loss-causes\"><span style=\"font-weight: 400;\">Hair loss<\/span><\/a><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Menstrual irregularities<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Fatigue<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span style=\"font-weight: 400;\">Source: DailyMed (<\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=5be7ee95-a27e-409d-881f-927f42074033\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Synthroid<\/span><\/a><span style=\"font-weight: 400;\">\/<\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=227e445c-b03d-44a3-b911-f00d3b2e118f#_OVERDOSAGE\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Armour Thyroid<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/p>\n<h2 id=\"synthroid-armour-thyroid-drug-interactions\"><span style=\"font-weight: 400;\">Synthroid &amp; Armour Thyroid drug interactions<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Drug interactions with Synthroid and Armour Thyroid tend to result in decreased thyroid hormone absorption. The interplay between drugs and hormones can be complicated, so it&rsquo;s essential to seek medical advice from your healthcare provider or pharmacist if you are using Synthroid or Armour Thyroid along with other medications or supplements.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">According to <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25040647\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">an observational study<\/span><\/a><span style=\"font-weight: 400;\"> that included 10,999 patients, the most common drug interactions with Synthroid (levothyroxine) are iron, calcium, proton pump inhibitors, statins, and estrogens. These medications increase thyroid stimulating hormone (TSH), which helps regulate hormones made by the thyroid, in patients taking levothyroxine. Since these medications throw off the hormone balance, they may also <\/span><a href=\"https:\/\/www.rxabbvie.com\/pdf\/armour_thyroid_pi.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">interact with Armour Thyroid<\/span><\/a><span style=\"font-weight: 400;\">.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">According to the <\/span><a href=\"https:\/\/www.thyroid.org\/thyroid-hormone-treatment\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">American Thyroid Association<\/span><\/a><span style=\"font-weight: 400;\">, thyroid hormone dosage may need to be adjusted for patients taking birth control pills, estrogen or testosterone, heart medications, anti-seizure medications, lithium, iron, calcium, and some cholesterol-lowering medications.<\/span><\/p>\n<p>&nbsp;<\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h3 id=\"compare-drug-interactions-synthroid-vs-armour-thyroid\"><span class=\"title\">Compare drug interactions: Synthroid vs. Armour Thyroid&nbsp;<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><b>Drug class<\/b><\/td>\n<td><b>Examples<\/b><\/td>\n<td><b>Interact with Synthroid?<\/b><\/td>\n<td><b>Interact with Armour Thyroid?<\/b><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Iron<\/span><\/td>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/iron\"><span style=\"font-weight: 400;\">Iron supplement<\/span><\/a><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Blood thinners<\/span><\/td>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/warfarin-sodium\/what-is\"><span style=\"font-weight: 400;\">Warfarin<\/span><\/a><span style=\"font-weight: 400;\">, Heparin<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/antacid\"><span style=\"font-weight: 400;\">Antacids<\/span><\/a><span style=\"font-weight: 400;\"> containing calcium<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Tums, Alka-Seltzer, Rolaids<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/conditions\/diabetes-treatment-and-medications\"><span style=\"font-weight: 400;\">Antidiabetics<\/span><\/a><\/td>\n<td><span style=\"font-weight: 400;\">Insulin, Diabinese, Glucotrol<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/drug-classes\/contraceptives\"><span style=\"font-weight: 400;\">Oral contraceptives<\/span><\/a><\/td>\n<td><span style=\"font-weight: 400;\">Estrogen, Progesterone&nbsp;<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/drug-classes\/bile-acid-sequestrants\"><span style=\"font-weight: 400;\">Bile acid sequestrants<\/span><\/a><\/td>\n<td><span style=\"font-weight: 400;\">Cholestyramine, Colestipol<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/drug-classes\/proton-pump-inhibitors\"><span style=\"font-weight: 400;\">Proton pump inhibitors<\/span><\/a><\/td>\n<td><span style=\"font-weight: 400;\">Omeprazole,<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Esomeprazole,<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Lansoprazole,<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Dexlansoprazole,<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Pantoprazole,<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Rabeprazole<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Anticonvulsants<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Phenytoin, Carbamazepine<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Antimanic<\/span><\/td>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/lithium\/what-is\"><span style=\"font-weight: 400;\">Lithium<\/span><\/a><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<h2 id=\"synthroid-armour-thyroid-drug-warnings\"><span style=\"font-weight: 400;\">Synthroid &amp; Armour Thyroid drug warnings<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Synthroid and Armour Thyroid both have an FDA boxed warning (once known as a black box warning) advising against taking them for weight loss. <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK538521\/#:~:text=Boxed%20warnings%20(formerly%20known%20as,major%20risks%20of%20the%20drug.\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Box warnings<\/span><\/a><span style=\"font-weight: 400;\"> are the strongest safety-related warnings that alert healthcare providers and patients about dangerous uses and harmful effects.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Even when taken to supplement thyroid hormone levels, there are still serious possible side effects to be aware of. Severe diarrhea and intense sweating should be reported to a healthcare provider immediately. These are signs of hyperthyroidism&mdash;too much thyroid hormone due to overdosage. To prevent this, keep all appointments for blood tests that measure your hormone levels.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Also, let your healthcare provider know if you are pregnant or breastfeeding. According to <\/span><a href=\"https:\/\/www.marchofdimes.org\/find-support\/topics\/pregnancy\/thyroid-conditions-during-pregnancy#:~:text=Levothyroxine%20replaces%20the%20thyroid%20hormone,safe%20to%20use%20during%20pregnancy.\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">March of Dimes<\/span><\/a><span style=\"font-weight: 400;\">, Synthroid can be taken during pregnancy, but Armour Thyroid cannot.<\/span><\/p>\n<h2 id=\"bottom-line-armour-thyroid-vs-synthroid\"><span style=\"font-weight: 400;\">Bottom line: Armour Thyroid vs. Synthroid&nbsp;<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Synthroid and Armour Thyroid are both intended to treat hypothyroidism. They replace thyroid hormones in patients whose thyroids do not secrete enough hormones naturally.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Synthroid is a synthetic form of T4, while Armour Thyroid is an animal-derived form of T3 and T4. Both Synthroid and Armour Thyroid are brand-name drugs, but Synthroid is available in a generic form, which can be more affordable.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Both Synthroid and Armour Thyroid can be effective treatments for hypothyroidism. Only a healthcare provider with a complete picture of your health and medication list can recommend which one is better for you.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Key differences&#9474;Conditions treated&#9474;Insurance and cost&#9474;Side effects&#9474;Warnings&#9474;Bottom line Armour Thyroid and Synthroid are both brand-name medications used to treat an underactive thyroid gland (hypothyroidism). They are part of the thyroid hormone drug class and work by supplementing thyroid hormones that are usually produced by the body. While both medications are known as thyroid agents, they have [&hellip;]<\/p>\n","protected":false},"author":149,"featured_media":628106,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[8313],"tags":[4343,3896],"coauthors":[20942],"class_list":["post-628104","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-vs-drug","tag-brand-name-drugs","tag-thyroid","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Armour Thyroid vs. Synthroid: Differences, similarities &amp; side effects<\/title>\n<meta name=\"description\" content=\"Armour Thyroid vs Synthroid treat [condition] but they work in different ways. 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