{"id":628379,"date":"2024-05-24T13:51:45","date_gmt":"2024-05-24T17:51:45","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=628379"},"modified":"2025-08-20T13:26:35","modified_gmt":"2025-08-20T17:26:35","slug":"metformin-over-the-counter","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/metformin-over-the-counter\/","title":{"rendered":"Can you buy metformin over the counter?"},"content":{"rendered":"<p><a href=\"https:\/\/www.singlecare.com\/prescription\/metformin\"><span style=\"font-weight: 400;\">Metformin<\/span><\/a><span style=\"font-weight: 400;\">\u00a0is a generic drug <\/span><a href=\"https:\/\/nctr-crs.fda.gov\/fdalabel\/services\/spl\/set-ids\/45cc673a-e125-4d76-8013-89a089eb0ae9\/spl-doc\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">approved<\/span><\/a><span style=\"font-weight: 400;\"> by the Food and Drug Administration (FDA) to help manage blood sugar levels in people with <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/type-2-diabetes-treatment-and-medications\"><span style=\"font-weight: 400;\">Type 2 diabetes mellitus<\/span><\/a><span style=\"font-weight: 400;\">. It can also be used <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/off-label-prescription-drugs\/\"><span style=\"font-weight: 400;\">off-label<\/span><\/a><span style=\"font-weight: 400;\"> for weight loss. Healthcare providers typically prescribe <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/metformin\/what-is\"><span style=\"font-weight: 400;\">metformin<\/span><\/a><span style=\"font-weight: 400;\"> along with a healthy diet and regular exercise routine. Often referred to by its brand names Glucophage, Fortamet, and Glumetza, metformin is available as an oral tablet and oral solution. Metformin tablets come in immediate-release or extended-release form.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Metformin is only available by prescription and is not sold over the counter (OTC). Therefore, you will need a prescription from a licensed healthcare provider to obtain the medication.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Read on to learn more about how to access metformin and if it\u2019s available over the counter.\u00a0<\/span><\/p>\n<h2 id=\"can-you-get-metformin-over-the-counter\"><span style=\"font-weight: 400;\">Can you get metformin over the counter?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Unfortunately, metformin isn\u2019t available over the counter or without a prescription in the United States. <\/span><span style=\"font-weight: 400;\">To get the medication, you will need a <\/span><span style=\"font-weight: 400;\">metformin prescription<\/span><span style=\"font-weight: 400;\"> from a licensed <\/span><span style=\"font-weight: 400;\">medical provider<\/span><span style=\"font-weight: 400;\">.<\/span><span style=\"font-weight: 400;\"> Although it\u2019s rare, metformin can cause serious <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/metformin-side-effects\/\"><span style=\"font-weight: 400;\">side effects<\/span><\/a><span style=\"font-weight: 400;\"> such as lactic acidosis. Because of this, it isn\u2019t the right choice for everyone. Healthcare providers will typically only prescribe metformin after thoroughly evaluating your medical history.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">While metformin isn\u2019t available without a prescription, there are some OTC options that may help with diabetes symptoms or weight management. There are also natural supplements that claim to help with blood sugar levels and weight loss.\u00a0<\/span><\/p>\n<h2 id=\"otc-substitutes-for-metformin\"><span style=\"font-weight: 400;\">OTC substitutes for metformin<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">There are no exact OTC substitutes for metformin, and there aren\u2019t any FDA-approved OTC medications for diabetes. However, if you\u2019re looking for a metformin alternative for weight loss, there is one OTC weight-loss medication available called <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/alli\"><span style=\"font-weight: 400;\">Alli<\/span><\/a><span style=\"font-weight: 400;\"> (orlistat).\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Read on to learn more about OTC substitutes for metformin.\u00a0<\/span><\/p>\n<h3 id=\"otc-metformin-substitutes-for-diabetes\"><span style=\"font-weight: 400;\">OTC metformin substitutes for diabetes<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">While there aren\u2019t any OTC equivalents to metformin, there may be some OTC medications that can help with certain symptoms of diabetes. For example, doctors <\/span><a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/diabetic-neuropathy\/diagnosis-treatment\/drc-20371587\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">may recommend<\/span><\/a><span style=\"font-weight: 400;\"> OTC pain-relieving medications in combination with prescription medications to relieve <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/peripheral-diabetic-neuropathy-treatment-and-medications\"><span style=\"font-weight: 400;\">diabetic neuropathy<\/span><\/a><span style=\"font-weight: 400;\">, a type of nerve damage caused by diabetes. Examples of OTC pain relievers include Motrin (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/ibuprofen\"><span style=\"font-weight: 400;\">ibuprofen<\/span><\/a><span style=\"font-weight: 400;\">) and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/tylenol\"><span style=\"font-weight: 400;\">Tylenol<\/span><\/a><span style=\"font-weight: 400;\"> (acetaminophen). However, <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/antidepressants\"><span style=\"font-weight: 400;\">antidepressants<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/anticonvulsants\"><span style=\"font-weight: 400;\">anticonvulsants<\/span><\/a><span style=\"font-weight: 400;\">, and topical anesthetics are the <\/span><a href=\"https:\/\/www.niddk.nih.gov\/health-information\/diabetes\/overview\/preventing-problems\/nerve-damage-diabetic-neuropathies\/peripheral-neuropathy\"><span style=\"font-weight: 400;\">first-line treatments<\/span><\/a><span style=\"font-weight: 400;\"> for diabetic neuropathy <\/span><span style=\"font-weight: 400;\">and these are <\/span><span style=\"font-weight: 400;\">prescription drugs<\/span><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h3 id=\"otc-metformin-substitutes-for-weight-loss\"><span style=\"font-weight: 400;\">OTC metformin substitutes for weight loss<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">In certain situations, healthcare providers may prescribe metformin off-label for weight loss. In a <\/span><a href=\"https:\/\/diabetesjournals.org\/care\/article\/35\/4\/731\/38345\/Long-Term-Safety-Tolerability-and-Weight-Loss\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">2012 study<\/span><\/a><span style=\"font-weight: 400;\">, researchers found the average weight loss was 2.7 kilograms (about 6 pounds) after 1 year of taking metformin. The study also found that while gastrointestinal (GI) side effects were more common in people taking metformin, these side effects declined over time and there were no significant safety issues that occurred.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">For weight loss, the only FDA-approved OTC weight-loss pill available is <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/fda\/fdaDrugXsl.cfm?setid=a2d3bd73-f3af-4ea5-a57c-66b0004cfe4f&amp;type=display\"><span style=\"font-weight: 400;\">Alli<\/span><\/a><span style=\"font-weight: 400;\"> (orlistat). By lowering the amount of fat absorbed by the body, Alli can be used for weight loss in adults 18 years and older along with a reduced-calorie and low-fat diet. In studies, Alli helped people lose <\/span><a href=\"https:\/\/www.myalli.com\/alli-faq\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">50% more weight<\/span><\/a><span style=\"font-weight: 400;\"> than with diet alone. This means if you lost 10 pounds with diet alone, Alli may help you lose 5 additional pounds. Nevertheless, Alli can cause side effects, including digestive symptoms. And although it\u2019s rare, severe liver problems have been <\/span><a href=\"https:\/\/www.fda.gov\/drugs\/postmarket-drug-safety-information-patients-and-providers\/fda-drug-safety-communication-completed-safety-review-xenicalalli-orlistat-and-severe-liver-injury\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">reported<\/span><\/a><span style=\"font-weight: 400;\"> with Alli.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Whatever the reason is for seeking an OTC substitute for metformin, be sure to check with your healthcare provider or pharmacist before starting a new medication. This can help prevent <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/metformin-interactions\/\"><span style=\"font-weight: 400;\">drug interactions<\/span><\/a><span style=\"font-weight: 400;\">, which can cause medications to be less effective or increase your risk of side effects.\u00a0<\/span><\/p>\n<h2 id=\"what-are-some-natural-alternatives-to-metformin\"><span style=\"font-weight: 400;\">What are some natural alternatives to metformin?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">There aren\u2019t any FDA-approved natural alternatives to metformin. That said, some natural supplements claim they can help manage blood glucose levels or weight loss. But it\u2019s important to keep in mind that <\/span><a href=\"https:\/\/www.fda.gov\/news-events\/rumor-control\/facts-about-dietary-supplements\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">supplements<\/span><\/a><span style=\"font-weight: 400;\"> differ from OTC medications because they contain natural ingredients. They aren\u2019t approved by the FDA for safety or effectiveness before they are sold to the public.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Examples of natural supplements that may lower blood sugar include:<\/span><\/p>\n<ul>\n<li aria-level=\"1\"><b>Berberine<\/b><span style=\"font-weight: 400;\">: Berberine is a compound found in several plants. It\u2019s commonly used in Chinese medicine for a variety of medical problems, including high blood sugar levels. <\/span><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2211383512000871\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Research<\/span><\/a><span style=\"font-weight: 400;\"> suggests berberine may help lower blood sugar levels in various ways, such as increasing insulin sensitivity and improving insulin release. In a <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18397984\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">2008 study<\/span><\/a><span style=\"font-weight: 400;\">, researchers found berberine was safe and effective for the treatment of type 2 diabetes. At a dosage of 1 gram daily, berberine lowered hemoglobin A1C levels by 12%.<\/span><\/li>\n<li aria-level=\"1\"><b>CinSulin<\/b><span style=\"font-weight: 400;\">: Cinnamon is commonly marketed as a supplement <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4609100\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">that can help<\/span><\/a><span style=\"font-weight: 400;\"> support obesity, diabetes, and high cholesterol. CinSulin is a spray-dried, water extract of cinnamon. In a <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27774415\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">2015 study<\/span><\/a><span style=\"font-weight: 400;\">, CinSulin was found to decrease fasting glucose more significantly than a placebo.\u00a0<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">The following are examples of natural supplements that may support weight loss.<\/span><\/p>\n<ul>\n<li><b>Glucomannan<\/b><span style=\"font-weight: 400;\">: <\/span><a href=\"https:\/\/ods.od.nih.gov\/factsheets\/WeightLoss-HealthProfessional\/#glucomannan\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Glucomannan<\/span><\/a><span style=\"font-weight: 400;\"> is a soluble fiber that can make you feel fuller, slows digestion in the stomach, and lowers fat and protein absorption. In theory, this may help you lose weight but its effects on weight loss have been inconsistent.\u00a0<\/span><\/li>\n<li><b>Green tea and green tea extract<\/b><span style=\"font-weight: 400;\">: Green tea and green tea extract may speed up breakdown of fat and decrease fat absorption. In a <\/span><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S026156141500134X\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">2016 study<\/span><\/a><span style=\"font-weight: 400;\">, 12 weeks of high-dose green tea extract resulted in significant weight loss, decreases in body mass index (BMI), and waist circumference.<\/span><\/li>\n<li><b>Probiotics<\/b><span style=\"font-weight: 400;\">: The evidence is mixed on whether probiotics can support weight loss. But there is <\/span><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1111\/obr.12626\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">some research<\/span><\/a><span style=\"font-weight: 400;\"> that says probiotics can help reduce your body weight and fat percentage in comparison to placebo.\u00a0<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Although dietary supplements have their place in the diabetes and weight-loss market, it\u2019s a good idea to discuss their use with a healthcare professional before taking them. Despite their natural ingredients, they come with risks, just as any medications do. <\/span><span style=\"font-weight: 400;\">A <\/span><span style=\"font-weight: 400;\">healthcare provider<\/span><span style=\"font-weight: 400;\"> can help you decide if the supplement is right for you, given your <\/span><span style=\"font-weight: 400;\">medication<\/span><span style=\"font-weight: 400;\"> list and medical conditions. <\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Metformin\u00a0is a generic drug approved by the Food and Drug Administration (FDA) to help manage blood sugar levels in people with Type 2 diabetes mellitus. It can also be used off-label for weight loss. Healthcare providers typically prescribe metformin along with a healthy diet and regular exercise routine. Often referred to by its brand names [&hellip;]<\/p>\n","protected":false},"author":133,"featured_media":628380,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[10298,10708],"coauthors":[20969],"class_list":["post-628379","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-diabetes","tag-over-the-counter-medications","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Can you buy metformin over the counter?<\/title>\n<meta name=\"description\" content=\"Metformin is only available with an authorized prescription. However, there are some OTC options that may help ease diabetes symtoms. 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