{"id":628492,"date":"2024-06-07T12:27:12","date_gmt":"2024-06-07T16:27:12","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=628492"},"modified":"2025-10-20T15:01:04","modified_gmt":"2025-10-20T19:01:04","slug":"qulipta-vs-nurtec","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/qulipta-vs-nurtec\/","title":{"rendered":"Qulipta vs. Nurtec: Differences and similarities explained"},"content":{"rendered":"

Although migraines are common and sometimes hard to manage, relatively new treatment options like <\/span>Qulipta<\/span><\/a> (atogepant) and <\/span>Nurtec ODT<\/span><\/a> (rimegepant) can help make life easier. Both help prevent episodic migraines and work by blocking <\/span>calcitonin gene-related peptide (CGRP)<\/span><\/a>, a protein involved in inflammation in the brain. They\u2019re both CGRP receptor antagonists, but they may differ in approved uses, dosages, and potential costs or side effects.\u00a0<\/span><\/p>\n

Qulipta vs. Nurtec ODT: Key differences<\/span><\/h2>\n

Both <\/span>migraine medications<\/span><\/a> have similar mechanisms of action and are approved by the Food and Drug Administration (FDA). The main difference between Qulipta and Nurtec ODT is that they contain different active ingredients: Qulipta contains atogepant, while Nurtec ODT contains rimegepant.\u00a0<\/span><\/p>\n

In addition, they differ in their dosing and forms. Qulipta is a regular <\/span>oral tablet<\/span><\/a> that\u2019s taken daily to prevent migraines. On the other hand, Nurtec ODT is an <\/span>orally disintegrating tablet<\/span><\/a> that melts on or under the tongue and is taken as needed to relieve a migraine attack. It can also be taken every other day for preventive treatment.\u00a0<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n
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Compare Qulipta vs. Nurtec ODT key differences<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n

<\/td>\nQulipta<\/b><\/td>\nNurtec ODT<\/b><\/td>\n<\/tr>\n
Drug class<\/b><\/td>\nCGRP receptor antagonists, gepants\u00a0<\/span><\/td>\nCGRP receptor antagonists, gepants\u00a0<\/span><\/td>\n<\/tr>\n
Brand\/generic status<\/b><\/td>\nBrand<\/span><\/td>\nBrand<\/span><\/td>\n<\/tr>\n
What is the generic name?<\/b><\/td>\nAtogepant<\/span><\/td>\nRimegepant<\/span><\/td>\n<\/tr>\n
What form(s) does the drug come in?<\/b><\/td>\nTablet<\/span><\/td>\nOrally disintegrating tablet<\/span><\/td>\n<\/tr>\n
What is the standard dosage?<\/b><\/td>\n10 mg, 30 mg, or 60 mg once daily<\/span><\/td>\n75 mg as needed for acute migraine OR 75 mg every other day for prevention<\/span><\/p>\n

Maximum dosage of 75 mg per day and no more than 18 doses in a 30-day period<\/span><\/td>\n<\/tr>\n

How long is the typical treatment?<\/b><\/td>\nLong-term<\/span><\/td>\nLong-term<\/span><\/td>\n<\/tr>\n
Who typically uses the medication?<\/b><\/td>\nAdults<\/span><\/td>\nAdults\u00a0<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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Qulipta vs. Nurtec ODT: Conditions treated<\/span><\/h2>\n

Qulipta and Nurtec ODT are prescription options used for people living with migraine headaches, but they\u2019re FDA approved for slightly different uses.\u00a0<\/span><\/p>\n

Qulipta is approved to help prevent both <\/span>episodic and chronic migraines<\/span><\/a> in adults. It\u2019s taken every day to reduce the number of migraine days per month, whether a person has less frequent migraines (episodic) or more frequent ones (chronic).<\/span><\/p>\n

Nurtec ODT is approved to provide relief during acute migraine attacks. It’s also approved to prevent episodic migraines when taken every other day. However, it\u2019s not approved to prevent chronic migraines.<\/span><\/p>\n

The difference between <\/span>episodic and chronic migraines<\/span><\/a> is that episodic migraines occur less frequently, typically fewer than 15 days per month, while chronic migraines occur 15 or more days per month.<\/span><\/p>\n\n\n\n\n\n\n\n\n
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Compare conditions treated by Qulipta vs. Nurtec ODT<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n

Condition<\/b><\/td>\nQulipta<\/b><\/td>\nNurtec ODT<\/b><\/td>\n<\/tr>\n
Acute treatment of migraine with or without aura<\/strong><\/td>\nNo<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Preventive treatment of episodic migraines<\/strong><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Preventive treatment of chronic migraines<\/strong><\/td>\nYes<\/span><\/td>\nNo<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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Is Nurtec ODT better than Qulipta?<\/span><\/h2>\n

The better treatment option will depend on what it\u2019s being used for:<\/span><\/p>\n