{"id":628564,"date":"2024-06-11T12:32:50","date_gmt":"2024-06-11T16:32:50","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=628564"},"modified":"2024-10-25T09:54:50","modified_gmt":"2024-10-25T13:54:50","slug":"gabapentin-cause-ataxia-in-dogs","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/gabapentin-cause-ataxia-in-dogs\/","title":{"rendered":"Can gabapentin cause ataxia in dogs?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">If your dog suddenly starts walking funny, it can be pretty concerning. But it might be a simple side effect of medications like <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/gabapentin\/what-is\"><span style=\"font-weight: 400;\">gabapentin<\/span><\/a><span style=\"font-weight: 400;\"> (brand names: Horizant, Gralise, Neurontin). An anticonvulsant drug that vets often use for seizures, neuropathic pain, or anxiety, <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/gabapentin-for-dogs\/\"><span style=\"font-weight: 400;\">gabapentin for dogs<\/span><\/a><span style=\"font-weight: 400;\"> may also cause a loss of balance, coordination, and motor control in the limbs&mdash;a condition called ataxia. It&rsquo;s a fairly common side effect, especially at high doses, but it is important to know what causes it and what to do if it happens.&nbsp;<\/span><\/p>\n<h2 id=\"can-gabapentin-cause-ataxia-in-dogs\"><span style=\"font-weight: 400;\">Can gabapentin cause ataxia in dogs?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Any dog owner who sees their four-legged friend wobbling down the hall or falling over might want to know: Can gabapentin cause ataxia in dogs? It sure can. <\/span><a href=\"https:\/\/www.mdpi.com\/2076-2615\/14\/10\/1462\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Studies show<\/span><\/a><span style=\"font-weight: 400;\"> that sedation and ataxia are commonly reported side effects with higher doses of gabapentin.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Ataxia is a central nervous system condition that manifests as an inability to make normal, voluntary movements, like walking in a straight line. Depending on where it occurs in the central nervous system, it can affect the legs, body, or head. However, the clinical signs include an unsteady gait, awkward motions, muscle weakness, falling, or poor balance. If your dog looks uncharacteristically clumsy, it could have ataxia.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">&ldquo;Gabapentin works by affecting the central nervous system, which can lead to motor coordination issues in some dogs,&rdquo; says <\/span><a href=\"https:\/\/www.linkedin.com\/in\/sara-ochoa-37866a65\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Dr. Sara Ochoa, DVM<\/span><\/a><span style=\"font-weight: 400;\">, veterinarian at the Animal Hospital of West Monroe and co-founder of <\/span><a href=\"http:\/\/howto-pets.com\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Howto<\/span><span style=\"font-weight: 400;\">-pets.com<\/span><\/a><span style=\"font-weight: 400;\">. &ldquo;This disruption in the communication between the brain and the body can result in ataxia.&rdquo;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Sometimes, ataxia is only temporary, though. &ldquo;There may be an adjustment period when starting gabapentin. Some dogs may experience ataxia as a temporary side effect while their bodies adapt to the medication,&rdquo; Dr. Ochoa says. &ldquo;But each dog is unique, and their medication response can vary.&rdquo;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Gabapentin isn&rsquo;t the only cause of ataxia in dogs. It&rsquo;s one of several, including metabolic diseases like hypoglycemia, <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/dog-ear-infection\/\"><span style=\"font-weight: 400;\">middle and inner ear infections<\/span><\/a><span style=\"font-weight: 400;\">, inflammatory diseases, intervertebral disc disease (IVDD), degenerative myelopathy, spinal cord issues, head trauma, and brain tumors.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10536490\/\"><span style=\"font-weight: 400;\">one study on humans<\/span><\/a><span style=\"font-weight: 400;\">, 14% of subjects reported ataxia as a side effect of gabapentin. Researchers from <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10295034\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">four separate studies<\/span><\/a><span style=\"font-weight: 400;\"> have observed occasional episodes of ataxia in dogs after gabapentin administration, which makes it one of the drug&rsquo;s most common side effects. Not all pets will experience ataxia after the use of gabapentin, but some will, so monitor your dog closely for signs.&nbsp;<\/span><\/p>\n<h2 id=\"what-to-do-if-my-dog-cant-walk-because-of-gabapentin\"><span style=\"font-weight: 400;\">What to do if my dog can&rsquo;t walk because of gabapentin?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">First off, try not to panic. An ataxic dog might look like a dire situation, but if the ataxia comes solely from too much gabapentin, the dog should recover. &ldquo;The first thing to do is to immediately stop giving gabapentin to your dog and contact your veterinarian for further guidance,&rdquo; says Dr. Ochoa.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">But what should you do in the meantime? Per Dr. Ochoa, &ldquo;It&#8217;s important to stay calm. Your pooch is likely picking up on your emotions, so a soothing voice and gentle petting can reassure them that you&rsquo;re there to help. They may be confused or afraid if their legs aren&rsquo;t cooperating, so your comfort can make a big difference.&rdquo;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Dr. Sabrina Kong, DVM, a Staff Veterinarian Writer at<\/span> <a href=\"https:\/\/welovedoodles.com\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">WeLoveDoodles<\/span><\/a><span style=\"font-weight: 400;\">, adds, &ldquo;Keep your dog in a safe, confined area to prevent injuries from falls. Supportive care, such as helping your dog move, ensuring access to water, and providing a comfortable resting place, can aid their recovery. Your vet may also suggest physical therapy or other interventions to help regain mobility.&rdquo;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The prescribing veterinarian may recommend adjusting the dog&rsquo;s <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/gabapentin-dosage-for-dogs-by-weight\/\"><span style=\"font-weight: 400;\">dosage of gabapentin<\/span><\/a><span style=\"font-weight: 400;\"> since higher doses are more likely than low doses to cause ataxia. In certain cases, the vet might also recommend stopping the medication completely. But this depends on the condition they prescribed it to treat. If your pet has been on gabapentin for a long time, or if gabapentin is being used to treat seizures, your vet may suggest tapering the treatment off since suddenly halting gabapentin may cause seizures. Follow the vet&rsquo;s directions exactly, and your dog should be fine.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">This recovery isn&rsquo;t always quick, so Dr. Ochoa says giving your dog extra love, care, and positive reinforcement is important throughout the process. Then, keep an eye on their behavior and health going forward, noting any improvements or setbacks to discuss with the vet.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">It would take a lot of gabapentin for a dog to overdose, and an overdose is rarely fatal, but it&rsquo;s not impossible. Signs of a gabapentin overdose include severe lethargy, incoordination, diarrhea, and vomiting. Per the American Kennel Club, gabapentin will stay in a dog&rsquo;s system for around a day.&nbsp;<\/span><\/p>\n<h2 id=\"what-other-side-effects-can-gabapentin-cause-in-dogs\"><span style=\"font-weight: 400;\">What other side effects can gabapentin cause in dogs?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Lethargy and ataxia are two of the most common <\/span><a href=\"https:\/\/vcahospitals.com\/know-your-pet\/gabapentin\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">side effects of gabapentin<\/span><\/a><span style=\"font-weight: 400;\"> for dogs, but there are several other, less common ones to know. According to <\/span><a href=\"https:\/\/stud.epsilon.slu.se\/13297\/7\/Peck_C_180424.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">a 2017 questionnaire study<\/span><\/a><span style=\"font-weight: 400;\">, other possible side effects include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tremors<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nervousness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Increased sleep<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Increased appetite<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Abdominal pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Vomiting<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diarrhea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Constipation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Weight changes<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">&ldquo;The effects of gabapentin generally wear off within 24 hours, but this can vary depending on the dog&#8217;s metabolism, dosage, and frequency of administration,&rdquo; according to Dr. Kong. If you notice an adverse reaction in your dog, contact the vet for medical advice.&nbsp;<\/span><\/p>\n<h2 id=\"gabapentin-alternatives-for-dogs\"><span style=\"font-weight: 400;\">Gabapentin alternatives for dogs<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Gabapentin is a solid option for many dogs, but it&rsquo;s not the best option for every dog. Whether your dog has an allergy, the vet recommends against it, or you&rsquo;re worried about the potential side effects, some other treatment options are available. Which works best for your dog depends on their medical condition.<\/span><\/p>\n<h3 id=\"chronic-pain-medication-alternatives\"><span style=\"font-weight: 400;\">Chronic pain medication alternatives<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Just like for humans, non-steroidal anti-inflammatory drugs (NSAIDs) can help provide <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/pain-relief-for-dogs-cats\"><span style=\"font-weight: 400;\">pain relief<\/span><\/a><span style=\"font-weight: 400;\"> in dogs. FDA-approved <\/span><a href=\"https:\/\/www.fda.gov\/animal-veterinary\/animal-health-literacy\/get-facts-about-pain-relievers-pets\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">NSAIDs for dogs<\/span><\/a><span style=\"font-weight: 400;\"> include carprofen, deracoxib, firocoxib, grapiprant, and others. <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/tramadol-for-dogs\/\"><span style=\"font-weight: 400;\">An opioid called tramado<\/span><\/a><span style=\"font-weight: 400;\">l and an antiviral medicine called amantadine are also common for pain management in dogs.&nbsp;<\/span><\/p>\n<h3 id=\"anxiety-medication-alternatives\"><span style=\"font-weight: 400;\">Anxiety medication alternatives<\/span><\/h3>\n<p><a href=\"https:\/\/www.singlecare.com\/blog\/dog-anxiety-medication\/\"><span style=\"font-weight: 400;\">Dogs with anxiety<\/span><\/a><span style=\"font-weight: 400;\"> also often respond well to benzodiazepines like Xanax and Valium, as well as selective serotonin-reuptake inhibitors (SSRIs) like <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/putting-dog-prozac-anti-anxiety-medication\"><span style=\"font-weight: 400;\">Prozac<\/span><\/a><span style=\"font-weight: 400;\"> and Zoloft. <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/trazodone-for-dogs\/\"><span style=\"font-weight: 400;\">Trazodone<\/span><\/a><span style=\"font-weight: 400;\"> is another common substitute, as is clomipramine.<\/span><\/p>\n<h3 id=\"seizure-medication-alternatives\"><span style=\"font-weight: 400;\">Seizure medication alternatives<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">For dogs with epilepsy or other <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/dog-seizures\/\"><span style=\"font-weight: 400;\">seizure conditions<\/span><\/a><span style=\"font-weight: 400;\">, the <\/span><a href=\"https:\/\/www.merckvetmanual.com\/pharmacology\/systemic-pharmacotherapeutics-of-the-nervous-system\/antiepileptic-drugs-used-to-stop-ongoing-seizure-activity\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Merck Veterinary Manual <\/span><\/a><span style=\"font-weight: 400;\">recommends anti-seizure medications like benzodiazepines (diazepam and clonazepam) or barbiturates (phenobarbital and propofol).&nbsp;&nbsp;<\/span><\/p>\n<h3 id=\"natural-alternatives\"><span style=\"font-weight: 400;\">Natural alternatives<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Drugs aren&rsquo;t the only solution for dogs with chronic pain, anxiety, or even seizures. <\/span><a href=\"https:\/\/www.vet.cornell.edu\/departments\/riney-canine-health-center\/canine-health-information\/cbd-what-you-need-know-about-its-uses-and-efficacy\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">A study from Cornell University<\/span><\/a><span style=\"font-weight: 400;\"> showed that CBD oil or supplements reduce osteoarthritis pain in 80% of canine subjects and reduce anxiety before a stressful event in 83%. <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31067185\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Another study <\/span><\/a><span style=\"font-weight: 400;\">showed that dogs who took CBD had a significant reduction in seizure frequency. Tumeric has also <\/span><a href=\"https:\/\/www.mdpi.com\/1422-0067\/24\/19\/14561\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">shown some effectiveness<\/span><\/a><span style=\"font-weight: 400;\"> in treating canine osteoarthritis and degenerative myelopathy.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Dr. Ochoa and Dr. Kong both recommend glucosamine and chondroitin to support joint health and potentially reduce future pain. They also agree that omega-3 fatty acids can help joints, especially for dogs with inflammatory conditions. <\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>If your dog suddenly starts walking funny, it can be pretty concerning. But it might be a simple side effect of medications like gabapentin (brand names: Horizant, Gralise, Neurontin). An anticonvulsant drug that vets often use for seizures, neuropathic pain, or anxiety, gabapentin for dogs may also cause a loss of balance, coordination, and motor [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":628566,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[7956],"tags":[7969],"coauthors":[8861],"class_list":["post-628564","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pets","tag-dogs","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Ataxia in dogs taking gabapentin<\/title>\n<meta name=\"description\" content=\"Gabapentin may cause loss of balance, coordination, and motor control in the limbs of dogs. 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