{"id":628662,"date":"2024-07-05T09:30:36","date_gmt":"2024-07-05T13:30:36","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=628662"},"modified":"2024-10-25T09:52:04","modified_gmt":"2024-10-25T13:52:04","slug":"does-doxycycline-make-you-tired","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/does-doxycycline-make-you-tired\/","title":{"rendered":"Does doxycycline make you tired?"},"content":{"rendered":"<p><a href=\"https:\/\/www.singlecare.com\/prescription\/doxycycline\/what-is\"><span style=\"font-weight: 400;\">Doxycycline<\/span><\/a><span style=\"font-weight: 400;\"> is a powerful tetracycline antibiotic that can <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK555888\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">treat<\/span><\/a><span style=\"font-weight: 400;\"> a wide range of bacterial infections. Also sold under the brand names <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/vibramycin\"><span style=\"font-weight: 400;\">Vibramycin<\/span><\/a><span style=\"font-weight: 400;\"> and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/doryx-mpc\"><span style=\"font-weight: 400;\">Doryx<\/span><\/a><span style=\"font-weight: 400;\">, it&rsquo;s prescribed for sexually transmitted diseases (like chlamydia), severe acne or rosacea, respiratory infections, and Lyme disease. It can even prevent life-threatening medical conditions such as anthrax. If you&rsquo;re taking this antibiotic, you may feel tired. Drowsiness is not a side effect of this medication. It may be a symptom of the infection that <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/doxycycline-hyclate\"><span style=\"font-weight: 400;\">doxycycline<\/span><\/a><span style=\"font-weight: 400;\"> is prescribed to treat. Here&rsquo;s what you need to know about doxycycline-related fatigue, plus what you can do to feel better.<\/span><\/p>\n<h2 id=\"does-doxycycline-make-you-tired\"><span style=\"font-weight: 400;\">Does doxycycline make you tired?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">D<\/span><span style=\"font-weight: 400;\">rowsiness is not a typical doxycycline side effect, <\/span><span style=\"font-weight: 400;\">according to<\/span> <a href=\"http:\/\/www.dr911md.com\/bio.php\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Robert Glatter, MD<\/span><\/a><span style=\"font-weight: 400;\">, a board-certified emergency medicine physician<\/span> <span style=\"font-weight: 400;\">and assistant professor of emergency medicine at Northwell Health in New York<\/span><span style=\"font-weight: 400;\">. However, some individuals may experience increased fatigue while on doxycycline as part of the body&#8217;s natural response to a <\/span><a href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/24189-bacterial-infection\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">bacterial infection<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">&ldquo;Drowsiness or fatigue is typically from the infection itself&mdash;not from taking the antibiotic,&rdquo; Dr. Glatter says. <\/span><span style=\"font-weight: 400;\">The most common symptoms <\/span><span style=\"font-weight: 400;\">of<\/span><span style=\"font-weight: 400;\"> bacterial infections are <\/span><span style=\"font-weight: 400;\">fever, chills, headache, and fatigue.<\/span><span style=\"font-weight: 400;\"> In other words, while you may experience low energy levels from the illness this antibiotic is prescribed to treat, doxycycline doesn&rsquo;t cause fatigue.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Although doxycycline is unlikely to make you tired, it does increase sun sensitivity, making it more likely for you to get a <\/span><a href=\"https:\/\/www.mayoclinic.org\/drugs-supplements\/doxycycline-oral-route\/precautions\/drg-20068229#\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">severe sunburn<\/span><\/a><span style=\"font-weight: 400;\">. Sunburns, especially in severe cases, may cause <\/span><a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/sunburn\/symptoms-causes\/syc-20355922\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">fatigue<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Gastrointestinal side effects such as nausea and vomiting are also common with doxycycline. You may feel <\/span><a href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/9013-dehydration\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">more tired<\/span><\/a><span style=\"font-weight: 400;\"> If you become dehydrated due to these symptoms.&nbsp;<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/finish-antibiotics\/\"><b>What happens if you don&rsquo;t finish antibiotics?<\/b><\/a><\/p>\n<h2 id=\"doxycycline-side-effects\"><span style=\"font-weight: 400;\">Doxycycline side effects<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/doxycycline-hyclate-side-effects\/\"><span style=\"font-weight: 400;\">common side effects of doxycycline<\/span><\/a><span style=\"font-weight: 400;\"> include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea, vomiting, and loss of appetite<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stomach cramps<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diarrhea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Itching of the rectum<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Vaginal discharge, redness, burning, irritation, itching, or swelling<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pain or difficulty when urinating<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nasal congestion<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sore nose or throat<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Headache<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Swollen tongue or dry mouth<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Back or muscle pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Anxiety<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Yeast infections<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Inflammation of the lining of the heart<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sensitivity to sunlight<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Skin discoloration<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kidney dysfunction<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Most of these side effects are short-term and end with discontinuation of the medication. However, in children or breastfed infants, doxycycline can cause permanent tooth discoloration.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Although rare, more serious side effects may occur, such as:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Blurred vision, double vision, or loss of vision<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Rash with fever or swollen glands<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hives or skin reactions, such as peeling or blistering<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Signs of an allergic reaction, such as trouble breathing or swallowing or swelling of the lips, tongue, throat, eyes, or face<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Unusual bruising or bleeding<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Watery or bloody stools, stomach cramps, or fever that lasts after completing treatment<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Signs of infection, such as a fever, sore throat, or chills<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Joint pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Blood disorders<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Liver dysfunction<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/pancreatitis-treatment-and-medications\"><span style=\"font-weight: 400;\">Pancreatitis<\/span><\/a><span style=\"font-weight: 400;\"> (inflammation or infection of the pancreas)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Esophagitis (inflammation of the lining of the esophagus) or esophageal ulcer<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Intracranial hypertension (high skull pressure)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Clostridium difficile infection<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Autoimmune reactions<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">The following individuals should seek medical advice from a healthcare professional before taking doxycycline, as it may be dangerous in these groups:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pregnant or breastfeeding women<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Children younger than 12<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Individuals with liver disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Those with a recent case of colitis caused by antibiotic use<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">People with kidney disease&nbsp;<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Individuals with a history of <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/lupus-treatment-and-medications\"><span style=\"font-weight: 400;\">lupus<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Patients with porphyria (a blood disease)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/myasthenia-gravis-treatment-and-medications\"><span style=\"font-weight: 400;\">Myasthenia gravis<\/span><\/a><span style=\"font-weight: 400;\"> (an autoimmune disease causing involuntary muscle contractions)<\/span><\/li>\n<\/ul>\n<h2 id=\"doxycycline-interactions\"><span style=\"font-weight: 400;\">Doxycycline interactions<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Doxycycline should not be combined with:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Warfarin<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Penicillin<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Amoxicillin<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Isotretinoin<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Potential drug interactions may occur. <\/span><span style=\"font-weight: 400;\">Doxycycline may <\/span><a href=\"https:\/\/www.fda.gov\/drugs\/bioterrorism-and-drug-preparedness\/questions-and-answers-consumers-doxycycline\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">decrease the effectiveness<\/span><\/a><span style=\"font-weight: 400;\"> of certain oral<\/span><span style=\"font-weight: 400;\"> contraceptives. <\/span><span style=\"font-weight: 400;\">Avoid taking <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/bismuth-subsalicylate\"><span style=\"font-weight: 400;\">bismuth subsalicylate<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">antacids, or supplements containing <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/magnesium\"><span style=\"font-weight: 400;\">&#8203;magnesium<\/span><\/a><span style=\"font-weight: 400;\">, aluminum, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/calcium-citrate\"><span style=\"font-weight: 400;\">calcium<\/span><\/a><span style=\"font-weight: 400;\">, or <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/ferrous-sulfate\"><span style=\"font-weight: 400;\">iron<\/span><\/a><span style=\"font-weight: 400;\"> within one to two hours of doxycycline.<\/span><\/p>\n<h2 id=\"what-to-do-if-doxycycline-makes-you-tired\"><span style=\"font-weight: 400;\">What to do if doxycycline makes you tired<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Though fatigue isn&rsquo;t caused by doxycycline, you may be feeling more tired than usual when you have a bacterial infection. The following <\/span><a href=\"https:\/\/www.upstate.edu\/whatsup\/2020\/0515-how-to-feel-better-tips-for-self-care-when-sick.php\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">tips<\/span><\/a><span style=\"font-weight: 400;\"> can help you manage fatigue while your body recovers from an illness:<\/span><\/p>\n<ul>\n<li><b>Get plenty of rest:<\/b> <span style=\"font-weight: 400;\">R<\/span><span style=\"font-weight: 400;\">esting and getting extra sleep are good ways to help your body recover from a bacterial infection and restore your energy, says <\/span><a href=\"https:\/\/www.linkedin.com\/in\/sazan-sylejmani-a6ba1080\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Sazan Sylejmani, Pharm.D.<\/span><\/a><span style=\"font-weight: 400;\">, owner and pharmacy manager at <\/span><a href=\"https:\/\/www.westmontpharmacy.com\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Westmont Pharmacy<\/span><\/a><span style=\"font-weight: 400;\"> in Illinois<\/span><span style=\"font-weight: 400;\">.&nbsp;<\/span><\/li>\n<li><b>Take the medication with food: <\/b><span style=\"font-weight: 400;\">&ldquo;Taking it with food and a full glass of water will prevent stomach upset,&rdquo; says Dr. Glatter. This can help you avoid side effects that could cause dehydration-related fatigue.<\/span><\/li>\n<li><b>Stay hydrated:<\/b><span style=\"font-weight: 400;\">&nbsp; Drinking plenty of fluids can help mitigate some side effects and help your immune system work to fight the infection.<\/span><\/li>\n<li aria-level=\"1\"><b>Wear protective clothing and sunscreen: <\/b><span style=\"font-weight: 400;\">If you need to be outside while taking doxycycline, these measures can prevent sunburn and the associated tiredness.<\/span><\/li>\n<li aria-level=\"1\"><b>Eat a healthy diet:<\/b><span style=\"font-weight: 400;\"> Eating a balanced diet with fruits, vegetables, and whole grains can support overall energy levels.<\/span><\/li>\n<li aria-level=\"1\"><b>Get some light exercise: <\/b><span style=\"font-weight: 400;\">Gentle activity, like walking, can boost energy levels. But listen to your body&mdash;only exercise if you&rsquo;re feeling up to it.<\/span><\/li>\n<li aria-level=\"1\"><b>Avoid alcohol:<\/b> <a href=\"https:\/\/www.mayoclinic.org\/healthy-lifestyle\/consumer-health\/expert-answers\/antibiotics-and-alcohol\/faq-20057946\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Alcohol<\/span><\/a><span style=\"font-weight: 400;\"> worsens side effects, decreases immune system function, and lowers your energy levels.<\/span><\/li>\n<li aria-level=\"1\"><b>Take probiotics:<\/b><span style=\"font-weight: 400;\"> It&rsquo;s important to <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/taking-probiotics-with-antibiotics\/\"><span style=\"font-weight: 400;\">take probiotics when you&rsquo;re on antibiotics<\/span><\/a><span style=\"font-weight: 400;\"> to <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3601687\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">replenish<\/span><\/a><span style=\"font-weight: 400;\"> the gut microbiome, which plays an essential role in immune system function.<\/span><\/li>\n<li aria-level=\"1\"><b>Consult your healthcare provider:<\/b><span style=\"font-weight: 400;\"> If your fatigue persists or is severe, consult with your prescribing provider. They may prescribe a different medication or dosage.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Any drowsiness you experience typically<\/span><span style=\"font-weight: 400;\"> subsides once the course of antibiotics is completed (usually a week or two). Why? Because that&rsquo;s about the time you&rsquo;ll be fully recovered from the infection&mdash;and any sunburns or gastrointestinal upset.<\/span><\/p>\n<h2 id=\"the-bottom-line-doxycycline-doesnt-cause-drowsiness\"><span style=\"font-weight: 400;\">The bottom line: Doxycycline doesn&rsquo;t cause drowsiness<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Fatigue isn&rsquo;t caused by doxycycline but rather the underlying infection it&rsquo;s treating. Tiredness could also be due to other side effects, such as sunburn from photosensitivity or dehydration from nausea and vomiting. You should see your healthcare provider if your fatigue is severe, persistent, or accompanied by other worrying symptoms like shortness of breath, chest pain, or severe dizziness, which may indicate a drug reaction, says Dr. Sylejmani.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Doxycycline is a powerful tetracycline antibiotic that can treat a wide range of bacterial infections. Also sold under the brand names Vibramycin and Doryx, it&rsquo;s prescribed for sexually transmitted diseases (like chlamydia), severe acne or rosacea, respiratory infections, and Lyme disease. It can even prevent life-threatening medical conditions such as anthrax. If you&rsquo;re taking this [&hellip;]<\/p>\n","protected":false},"author":135,"featured_media":628717,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[715,20954,12752],"coauthors":[20608],"class_list":["post-628662","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-antibiotics","tag-infections","tag-medication-side-effects","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.8 (Yoast SEO v27.8) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Does doxycycline make you tired?<\/title>\n<meta name=\"description\" content=\"Taking doxycycline for an infection? Fatigue isn&#039;t a direct side effect, but underlying infections, sunburn, or dehydration might cause it. 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Fatigue isn't a direct side effect, but underlying infections, sunburn, or dehydration might cause it. 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