{"id":628778,"date":"2024-07-01T12:05:42","date_gmt":"2024-07-01T16:05:42","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=628778"},"modified":"2025-04-16T10:20:41","modified_gmt":"2025-04-16T14:20:41","slug":"natural-substitutes-for-prednisone","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/natural-substitutes-for-prednisone\/","title":{"rendered":"6 natural alternatives for prednisone"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Prednisone is a glucocorticoid, often called a steroid. It is a prescription medication that manages conditions that need to suppress inflammation. It treats a wide variety of conditions, including asthma, allergic reactions, rheumatoid arthritis, eye or vision problems, autoimmune diseases, gastrointestinal issues such as inflammatory bowel disease, hormone disorders, skin diseases, soft tissue diseases, blood disorders, cancer, and other medical conditions.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">However, prednisone can cause negative <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/prednisone-side-effects\/\"><span style=\"font-weight: 400;\">side effects<\/span><\/a><span style=\"font-weight: 400;\">, such as stomach pain, unwanted hair growth, fluid retention, headaches, and more, as well as serious side effects , such as high blood pressure, steroid psychosis, and muscle damage. Considering these adverse side effects, some patients may prefer a less pharmacologic approach, especially if they need a solution for long-term use. Thankfully, several options are available. Curcumin, ginger, and palmitoylethanolamide are just a few examples of prednisone alternatives that experts recommend. Be sure to discuss this decision with your healthcare provider, as there are conditions that only a prescription-strength glucocorticoid can effectively treat.\u00a0<\/span><\/p>\n<h2 id=\"6-natural-alternatives-to-prednisone\"><span style=\"font-weight: 400;\">6 natural alternatives to prednisone\u00a0<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">First and foremost, it\u2019s important to note that prednisone users shouldn\u2019t stop prednisone and switch to an alternative without prior consultation with a healthcare provider. Patients who have been taking prednisone for more than two weeks need a gentle taper off the medicine, or the body may experience symptoms of cortisol deficiency.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Users may even want to work with professionals when deciding which prednisone alternative will work best for them. \u201cNatural supplements are most effective when prescribed at the right dose and the right duration, with the right product,\u201d says <\/span><a href=\"https:\/\/www.theshiftclinic.com\/team\/katherine-maslen\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Katherine Maslen, ND<\/span><\/a><span style=\"font-weight: 400;\">, a clinical naturopath, nutritionist, and founder of <\/span><a href=\"https:\/\/www.theshiftclinic.com\/\"><span style=\"font-weight: 400;\">The Shift Clinic<\/span><\/a><span style=\"font-weight: 400;\">. \u201cSeeing a qualified naturopathic physician or integrative doctor trained on using natural alternatives may give you better results than trying to self-prescribe.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">When it comes to picking a natural product, the \u201cbig thing to keep in mind is that the main mechanism of action of prednisone is by decreasing the inflammation, both locally and systemically, in the body,\u201d says <\/span><a href=\"https:\/\/www.spinemd.com\/medical_team\/dr-yash-mehta\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Dr. Yash Mehta, DO<\/span><\/a><span style=\"font-weight: 400;\">, an interventional spine and sports medicine doctor at Virginia Spine Institute. So, he recommends adding herbs and supplements that fight chronic <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/inflammation\/\"><span style=\"font-weight: 400;\">inflammation<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Maslen and Dr. Mehta share six natural alternatives available at local pharmacies.<\/span><\/p>\n<h3 id=\"1-turmeric\"><span style=\"font-weight: 400;\">1. Turmeric<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Turmeric is a well-trusted go-to supplement, as it\u2019s been <\/span><a href=\"https:\/\/www.mountsinai.org\/health-library\/herb\/turmeric\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">used in Ayurvedic and Chinese medicine<\/span><\/a><span style=\"font-weight: 400;\"> as an anti-inflammatory for thousands of years. It can help with arthritis, other joint disorders, exercise-induced inflammation, muscle soreness, allergies, and colitis, according to Dr. Mehta. \u201cTurmeric works by regulating inflammatory-signaling pathways and inhibiting the production of inflammatory mediators, which helps to boost the immune system,\u201d he says, noting patients can take as much as 1200 mg daily. \u201cAlso, it neutralizes free radicals and has detoxification abilities.\u201d A <\/span><a href=\"https:\/\/trialsjournal.biomedcentral.com\/articles\/10.1186\/s13063-019-3327-2\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">study in <\/span><i><span style=\"font-weight: 400;\">Trials<\/span><\/i><\/a><span style=\"font-weight: 400;\"> found it relieves pain symptoms and has fewer side effects.<\/span><\/p>\n<h3 id=\"2-bioavailable-curcuma\"><span style=\"font-weight: 400;\">2. Bioavailable curcuma<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Dr. Mehta also recommends curcumin, the active ingredient in turmeric, and a yellow pigment in <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7522354\/#\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Curcuma longa L. rhizome<\/span><\/a><span style=\"font-weight: 400;\">, which has been used for thousands of years. Maslen mentions <\/span><i><span style=\"font-weight: 400;\">bioavailable<\/span><\/i><span style=\"font-weight: 400;\"> curcuma. The \u201cbioavailable\u201d part refers to how easily the body can <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/vitamin-absorption\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">absorb the nutrients<\/span><\/a><span style=\"font-weight: 400;\">. Technology has allowed it to become that way, Maslen explains, because the curcuminoids in turmeric aren\u2019t very easily absorbed. Maslen believes it\u2019s the stronger option. \u201cThe bioavailable curcumins we have on the market these days are up to <\/span><a href=\"https:\/\/www.lifeextension.com\/magazine\/2020\/2\/major-curcumin-enhancement\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">45 times more absorbable<\/span><\/a><span style=\"font-weight: 400;\"> than regular turmeric and, therefore, are powerful agents for reducing inflammation,\u201d she says. \u201cCurcuma is probably the closest natural agent to prednisone because it covers more inflammatory pathways than any other herb.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Curcumin works by reducing inflammation and is useful to help decrease <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/best-eczema-treatment\/\"><span style=\"font-weight: 400;\">eczema<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/contact-dermatitis-treatment\/\"><span style=\"font-weight: 400;\">dermatitis<\/span><\/a><span style=\"font-weight: 400;\">, and <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/current-and-upcoming-chronic-pain-management\/\"><span style=\"font-weight: 400;\">chronic pain<\/span><\/a><span style=\"font-weight: 400;\"> from osteoarthritis, autoimmune conditions, and migraines. It also has fewer side effects, if any. Maslen continues that it is also compatible with most medications. \u201cCurcuma is generally regarded as safe, although always check with your physician if taking other medications.\u201d The dosage depends on various factors\u2014another reason to check with a healthcare professional\u2014but usually, Maslen says, one to two doses a day is enough. It\u2019s \u201cbest taken in divided doses to keep levels high.\u201d<\/span><\/p>\n<h3 id=\"3-ginger\"><span style=\"font-weight: 400;\">3. Ginger<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">According to Dr. Mehta, ginger is a general immune booster and helps with joint and bone health issues (such as osteoarthritis). Research backs up its <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3665023\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">anti-oxidative and anti-inflammatory properties<\/span><\/a><span style=\"font-weight: 400;\">, anti-cancer potential, and <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9654013\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">ability to relieve nausea<\/span><\/a><span style=\"font-weight: 400;\">. Dr. Mehta says adults can take as much as 1000 mg of ginger a day.<\/span><\/p>\n<h3 id=\"4-quercetin\"><span style=\"font-weight: 400;\">4. Quercetin<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">This antioxidant is another immune booster. \u201cQuercetin is well-researched for its impact on the immune system,\u201d Maslen says, noting it reduces inflammation and oxidative stress. She continues to say that it can also be used to treat eczema and allergies and may also be helpful for pain, hay fever, sinus issues, asthma, and other immune issues with concurrent inflammation. A <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10384403\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">study in <\/span><i><span style=\"font-weight: 400;\">Pharmaceuticals<\/span><\/i><\/a><span style=\"font-weight: 400;\"> mentions its antioxidant, antimicrobial, anti-inflammatory, antiviral, and anticancer properties, saying they\u2019ve been extensively studied. More specifically, the research says quercetin can help prevent chronic disease, <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/blood-pressure-levels\"><span style=\"font-weight: 400;\">lower blood pressure<\/span><\/a><span style=\"font-weight: 400;\">, reduce <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/cholesterol-levels-by-age-chart\/\"><span style=\"font-weight: 400;\">cholesterol levels<\/span><\/a><span style=\"font-weight: 400;\">, and improve endothelial function, making it promising for preventing and treating cardiovascular diseases.<\/span><\/p>\n<h3 id=\"5-glucosamine\"><span style=\"font-weight: 400;\">5. Glucosamine<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Glucosamine is another chemical the body naturally produces, but people can take it as a supplement for joint health. \u201cNatural glucosamine, or taking a supplement, can help with <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/arthritis-pain-relief\/\"><span style=\"font-weight: 400;\">osteoarthritis<\/span><\/a><span style=\"font-weight: 400;\"> and other chronic inflammatory conditions,\u201d Dr. Mehta says. The Glucosamine\/Chondroitin Arthritis Intervention Trial <\/span><a href=\"https:\/\/www.arthritis.org\/health-wellness\/treatment\/complementary-therapies\/supplements-and-vitamins\/expert-q-a-glucosamine-and-chondroitin-for-oa\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">(GAIT)<\/span><\/a><span style=\"font-weight: 400;\"> was a comprehensive, long-term study that found that the combination of glucosamine and chondroitin helped a small subgroup of people with moderate-to-severe knee pain. <\/span><a href=\"https:\/\/www.arthritis.org\/health-wellness\/treatment\/complementary-therapies\/supplements-and-vitamins\/glucosamine-chondroitin-osteoarthritis-pain\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">More recent studies<\/span><\/a><span style=\"font-weight: 400;\"> have found even more encouraging, consistent results. \u201cIt is believed that this is done by overall reduction of inflammation, although the mechanism is not quite understood,\u201d Dr. Mehta explains. He says as much as 1500 mg a day is okay to take.<\/span><\/p>\n<h3 id=\"6-palmitoylethanolamide-pea\"><span style=\"font-weight: 400;\">6. Palmitoylethanolamide (PEA)<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Palmitoylethanolamide (PEA) is another natural option found in the human body. Maslen says it\u2019s \u201csafe to use short-term and is well-tolerated by patients\u201d and \u201ccan also be used alongside most drugs.\u201d It\u2019s also found in small amounts in some foods, such as egg yolks and peanuts. Maslen adds that PEA has analgesic and anti-inflammatory properties, meaning it can effectively treat chronic pain and allergic rhinitis or hay fever.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">A <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10053226\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">study in <\/span><i><span style=\"font-weight: 400;\">Nutrients<\/span><\/i><\/a><span style=\"font-weight: 400;\"> affirms the former, finding \u201cPEA is an effective and well-tolerated treatment for chronic pain.\u201dIf a person decides to take this and it\u2019s okay with their doctor, Maslen has a few suggestions. \u201cPEA works best by starting with a loading dose and then tapering off once a result has been achieved,\u201d she says. \u201cIt is also helpful to take a break from time to time, as a tolerance can be built up.\u201d While users can build a tolerance to it, Maslen adds, and it works on the same pathways as cannabis, it doesn\u2019t have the same potential side effects, such as dependence.\u00a0<\/span><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h2 id=\"natural-alternatives-to-prednisone\"><span class=\"title\">Natural alternatives to prednisone<\/span><\/h2>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><span style=\"font-weight: 400;\">Natural alternative to prednisone<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Conditions treated<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Turmeric<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Arthritis, joint disorders, exercise-induced inflammation, muscle soreness, allergies, and colitis<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Bioavailable curcuma<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Chronic pain, osteoarthritis, autoimmune conditions, migraines, eczema, and dermatitis<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Ginger<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Osteoarthritis and other bone\/joint issues<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Liposomal quercetin<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Eczema, allergies or hay fever, pain, sinus issues, asthma, and other immune issues that cause inflammation<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Glucosamine<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Osteoarthritis and other inflammatory conditions<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Palmitoylethanolamide (PEA)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Chronic pain and allergic rhinitis or hay fever<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span style=\"font-weight: 400;\">In addition to these natural products, people looking for a more holistic approach can turn to <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/prednisone-alternatives\/\"><span style=\"font-weight: 400;\">natural remedies<\/span><\/a><span style=\"font-weight: 400;\"> such as drinking more water, adopting a Mediterranean diet, opting for moderate exercise with frequent breaks instead of long endurance exercises, and engaging in stress-busting activities.<\/span><\/p>\n\t\t<div id=\"coupon-cta\" class=\"coupon-cta master-template\">\n\t\t\t<p id=\"headline\">Save up to 80% on Prednisone with SingleCare<\/p>\n\t\t\t<p id=\"subheadline\">Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t<div class=\"details-wrap\">\n\t\t\t\t<div class=\"details\">\n\t\t\t\t\tPrednisone 20 mg (10 Tablets)\t\t\t\t<\/div>\n\t\t\t\t<div class=\"address\">\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"api-response\">\n\t\t\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-walmart-nbh-market.svg\" alt=\"Walmart Neighborhood Market\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$3.15<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/prednisone#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/prednisone#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-walmart.svg\" alt=\"Walmart Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$3.15<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/prednisone#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/prednisone#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/prednisone#blog-cta\" class=\"coupon-see-all-btn\">See Prednisone prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n<h2 id=\"when-to-see-your-healthcare-provider\"><span style=\"font-weight: 400;\">When to see your healthcare provider<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">With all of that said, at what point should people stop natural alternatives and seek medical treatment? \u201cIf symptoms are becoming worse or unmanageable, it is time to check in with a healthcare provider,\u201d Maslen recommends.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Dr. Mehta agrees, saying medical advice is also warranted if symptoms don\u2019t improve.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">When using (or considering using) natural substitutes for prednisone, remember they aren\u2019t helpful to the same extent. \u201cIt is important to know that while these are nowhere near as powerful as drugs like prednisone, they do have a place in the therapeutic toolkit when it comes to managing pain, inflammation, and immune disorders,\u201d Maslen says.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If and when a healthcare provider says <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/prednisone\"><span style=\"font-weight: 400;\">taking prednisone<\/span><\/a><span style=\"font-weight: 400;\"> (over a natural substitute) is a safe option, patients can buy it at a discounted rate using a <\/span><a href=\"https:\/\/www.singlecare.com\/prescription-discount-card\"><span style=\"font-weight: 400;\">SingleCare prescription discount card<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Prednisone is a glucocorticoid, often called a steroid. It is a prescription medication that manages conditions that need to suppress inflammation. It treats a wide variety of conditions, including asthma, allergic reactions, rheumatoid arthritis, eye or vision problems, autoimmune diseases, gastrointestinal issues such as inflammatory bowel disease, hormone disorders, skin diseases, soft tissue diseases, blood [&hellip;]<\/p>\n","protected":false},"author":133,"featured_media":628779,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[20955,812],"coauthors":[21001],"class_list":["post-628778","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-inflammation","tag-supplements","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>6 natural substitutes for prednisone<\/title>\n<meta name=\"description\" content=\"Explore natural alternatives for prednisone to help in managing inflammation. 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