{"id":628828,"date":"2024-07-03T11:27:40","date_gmt":"2024-07-03T15:27:40","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=628828"},"modified":"2025-12-18T09:18:47","modified_gmt":"2025-12-18T14:18:47","slug":"how-long-does-it-take-for-levothyroxine-to-work","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/how-long-does-it-take-for-levothyroxine-to-work\/","title":{"rendered":"How long does it take levothyroxine to work?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Levothyroxine, also known by brand names like Synthroid, Tirosint, and Levoxyl, is a thyroid medicine known as thyroid replacement therapy or thyroid hormone replacement. It is used in people with an underactive thyroid (hypothyroidism) and replaces the thyroid hormone the body normally makes. It is also used to treat certain types of thyroid cancer and thyroid disorders. Many people who start taking levothyroxine for hypothyroidism want to know how fast it will start working. The good news is that levothyroxine starts to work immediately for thyroid disease, but it may take up to four to six weeks to notice the medication&#8217;s full benefit. Continue reading to learn more about levothyroxine.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/prescription\/levothyroxine-sodium\/what-is\"><b>What is levothyroxine?<\/b><\/a><b> | <\/b><a href=\"https:\/\/www.singlecare.com\/prescription\/levothyroxine-sodium\"><b>Levothyroxine coupons<\/b><\/a><\/p>\n<h2 id=\"how-long-does-it-take-for-levothyroxine-to-work\"><span style=\"font-weight: 400;\">How long does it take for levothyroxine to work?\u00a0<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">When your healthcare provider prescribes levothyroxine, they will determine the starting dose depending on several factors, such as your age, weight, lab values, and other medications you take.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Levothyroxine starts to work immediately; however, it may take up to <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=a6233381-3043-4e9a-aaa6-a6b105e5142b\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">four to six weeks<\/span><\/a><span style=\"font-weight: 400;\"> to see its full effect. Even if you do not notice a difference in symptoms immediately, the medication takes time to start regulating your thyroid levels. It\u2019s important to continue to take your daily dose as directed.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">A dose adjustment may be required in some cases. Your healthcare provider will order blood work, generally about <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6822824\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">six weeks<\/span><\/a><span style=\"font-weight: 400;\"> after you start taking levothyroxine, to see how well the medication is working. The blood tests will check your <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/tsh-test\/\"><span style=\"font-weight: 400;\">thyroid-stimulating hormone (TSH)<\/span><\/a><span style=\"font-weight: 400;\"> levels to measure your thyroid function.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Once the medication reaches a steady level in the body, in about six weeks, your hypothyroidism symptoms should subside as your thyroid hormone levels regulate.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If, after several weeks, your symptoms worsen or do not improve, your healthcare provider may need to adjust the dose of your medicine. Generally, healthcare providers will <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK539808\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">check TSH levels and adjust doses<\/span><\/a><span style=\"font-weight: 400;\"> every six to eight weeks, if required, until thyroid levels normalize. Older adults or people with heart problems may be monitored more frequently, like every four to six weeks, until levels normalize. Once your healthcare provider determines that you are taking the right dose and your TSH level is appropriate, they may check again in three to six months, then every six to 12 months.\u00a0<\/span><\/p>\n<h2 id=\"how-do-you-know-levothyroxine-is-working\"><span style=\"font-weight: 400;\">How do you know levothyroxine is working?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Some <\/span><a href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/12120-hypothyroidism#symptoms-and-causes\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">common symptoms<\/span><\/a><span style=\"font-weight: 400;\"> of hypothyroidism include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fatigue\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Constipation\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Weight gain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sore muscles<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Depression\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dry skin and hair<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Feeling cold<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Brain fog<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Irregular heartbeats<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">If you are taking levothyroxine and you notice symptoms of hypothyroidism (low thyroid levels), consult your healthcare provider. You may need a higher dose of levothyroxine, which will normalize your TSH levels and reduce these symptoms.\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/14129-hyperthyroidism\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Common symptoms<\/span><\/a><span style=\"font-weight: 400;\"> of <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/hypethyroidism-treatment-and-medications\"><span style=\"font-weight: 400;\">hyperthyroidism<\/span><\/a><span style=\"font-weight: 400;\"> (overactive thyroid) include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fast heart rate or palpitations<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Chest pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Shakiness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nervousness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Weight loss<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Increased appetite<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diarrhea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Thin and warm skin<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Feeling hot; excess sweating<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Trouble sleeping<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Neck swelling from an enlarged thyroid gland (goiter)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hair loss<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Weak muscles<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Bulging eyes (seen with Graves\u2019 disease, a common cause of hyperthyroidism)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">If you take levothyroxine and notice symptoms of hyperthyroidism, you should consult your healthcare provider. You may require a lower dose of levothyroxine to help normalize TSH levels and reduce symptoms.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Side effects of levothyroxine are generally those of hyperthyroidism, which can occur when the dose is too high.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">As you can see, taking your medication as directed is important, and notify your healthcare provider if you notice any underactive or overactive thyroid symptoms.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/hypothyroidism-vs-hyperthyroidism\/\"><b>Hypothyroidism vs. hyperthyroidism<\/b><\/a><\/p>\n\t\t<div id=\"coupon-cta\" class=\"coupon-cta master-template\">\n\t\t\t<p id=\"headline\">Save up to 80% on Levothyroxine with SingleCare<\/p>\n\t\t\t<p id=\"subheadline\">Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t<div class=\"details-wrap\">\n\t\t\t\t<div class=\"details\">\n\t\t\t\t\tLevothyroxine 75 mcg (90 Tablets)\t\t\t\t<\/div>\n\t\t\t\t<div class=\"address\">\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"api-response\">\n\t\t\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-walmart-nbh-market.svg\" alt=\"Walmart Neighborhood Market\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$10.00<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/levothyroxine-sodium#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/levothyroxine-sodium#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-walmart.svg\" alt=\"Walmart Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$10.00<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/levothyroxine-sodium#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/levothyroxine-sodium#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/levothyroxine-sodium#blog-cta\" class=\"coupon-see-all-btn\">See Levothyroxine prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n<h2 id=\"what-is-the-standard-levothyroxine-dosage\"><span style=\"font-weight: 400;\">What is the standard levothyroxine dosage?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">There is no standard dose for levothyroxine, as the dosages vary based on various factors.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Levothyroxine tablets are available in the <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/synthroid\/dosage\"><span style=\"font-weight: 400;\">following strengths<\/span><\/a><span style=\"font-weight: 400;\">:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">25 micrograms (mcg)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">50 mcg<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">75 mcg<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">88 mcg<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">100 mcg<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">112 mcg<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">125 mcg\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">137 mcg<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">150 mcg\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">175 mcg\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">200 mcg\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">300 mcg<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">For those younger than 60, a general <\/span><a href=\"https:\/\/www.aafp.org\/pubs\/afp\/issues\/2021\/0515\/p605.html\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">starting dose<\/span><\/a><span style=\"font-weight: 400;\"> may be 1.5 to 1.8 mcg per kilogram (kg) daily.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">To translate this into a real-life example, if someone weighs 175 pounds, that equals about 80 kilograms. If the healthcare provider wants to start with 1.5 mcg per kg daily, they would multiply 1.5 x 80, and the answer would be 120.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Considering the available doses of levothyroxine above, the starting dose would be either 112 mcg or 125 mcg.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">For older adults or people with heart disease, healthcare providers generally follow the guidelines from 12.5 mcg to 50 mcg daily.\u00a0<\/span><\/p>\n<h2 id=\"tips-for-taking-levothyroxine\"><span style=\"font-weight: 400;\">Tips for taking levothyroxine<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Here are some tips for taking levothyroxine:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Before taking levothyroxine, tell your healthcare provider about any health conditions you have, including if you are pregnant, planning to become pregnant, or breastfeeding.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Take levothyroxine exactly as directed by your healthcare provider. Take only what is prescribed.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Take levothyroxine once daily on an empty stomach, 30 to 60 minutes before eating. Many patients take their daily dose before breakfast. Take your medicine with a full glass of water to avoid choking or gagging.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">See the next section for more information about the timing of certain other foods and medications.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">It may take several weeks until you notice your symptoms subside. Continue to take your medicine as directed.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">If you are scheduled for any type of surgery, tell your healthcare provider that you take levothyroxine.\u00a0<\/span><\/li>\n<\/ul>\n<h2 id=\"what-can-affect-how-long-it-takes-levothyroxine-to-work\"><span style=\"font-weight: 400;\">What can affect how long it takes levothyroxine to work?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Certain factors can affect the absorption of levothyroxine, such as the timing of medication, other foods, and other medications or supplements.<\/span><\/p>\n<h3 id=\"timing-of-medication\"><span style=\"font-weight: 400;\">Timing of medication\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Levothyroxine is best absorbed on an empty stomach. Many people take levothyroxine in the morning, 30 to 60 minutes before breakfast, as the prescribing information recommends.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Some individuals, though, prefer to <\/span><a href=\"https:\/\/www.uclahealth.org\/medical-services\/surgery\/endocrine-surgery\/conditions-treated\/thyroid\/how-should-i-take-thyroid-hormone\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">take levothyroxine at night<\/span><\/a><span style=\"font-weight: 400;\">. That is generally fine, as long as you take it at least three or four hours after your last meal of the day so that you take it on an empty stomach.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">It\u2019s also best to take levothyroxine at about the same time every day.\u00a0<\/span><\/p>\n<h3 id=\"foods\"><span style=\"font-weight: 400;\">Foods\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Certain foods or ingredients can interfere with the absorption of levothyroxine, including:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Soybean flour<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cottonseed meal<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Walnuts<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dietary fiber<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Grapefruit and grapefruit juice<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">If you consume anything on this list, consult your healthcare provider. <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/hypothyroidism-diet\/\"><span style=\"font-weight: 400;\">Avoiding these foods<\/span><\/a><span style=\"font-weight: 400;\"> or ingredients within an hour or two of taking your medication should suffice.<\/span><\/p>\n<h3 id=\"medications-or-supplements\"><span style=\"font-weight: 400;\">Medications or supplements<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Various medications, including certain prescription drugs, OTC meds, and dietary supplements, can interfere with the absorption of levothyroxine. If you take anything on the list below, avoid taking them for four hours before or four hours after taking levothyroxine:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Antacids such as Maalox, Mylanta, Milk of Magnesia<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/drug-classes\/bile-acid-sequestrants\"><span style=\"font-weight: 400;\">Bile acid sequestrants<\/span><\/a><span style=\"font-weight: 400;\"> such as Colestid (colestipol), Questran (cholestyramine), or Welchol (colesevelam)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Calcium products such as Tums or calcium vitamins<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Carafate (sucralfate)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Iron supplements<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kayexalate (sodium polystyrene sulfonate)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/drug-classes\/phosphate-binders\"><span style=\"font-weight: 400;\">Phosphate binders<\/span><\/a><span style=\"font-weight: 400;\"> such as Fosrenol (lanthanum), Renagel (sevelamer), or Renvela (sevelamer)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/drug-classes\/proton-pump-inhibitors\"><span style=\"font-weight: 400;\">Proton pump inhibitors<\/span><\/a><span style=\"font-weight: 400;\"> such as Nexium (esomeprazole) or Protonix (pantoprazole)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Other medications may affect levothyroxine as well. Consult your healthcare professional for more information and medical advice.\u00a0<\/span><\/p>\n<h2 id=\"the-bottom-line\"><span style=\"font-weight: 400;\">The bottom line<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">If you are taking levothyroxine for hypothyroidism, it may take up to six weeks to notice the full benefit of the medication. Take your medication once daily as directed, on an empty stomach\u2014and always with a full glass of water to prevent choking or gagging. Your healthcare provider will tell you when to follow up for blood work, and you should consult your provider if you notice any underactive or overactive thyroid symptoms, which may require a dosage adjustment.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Levothyroxine, also known by brand names like Synthroid, Tirosint, and Levoxyl, is a thyroid medicine known as thyroid replacement therapy or thyroid hormone replacement. It is used in people with an underactive thyroid (hypothyroidism) and replaces the thyroid hormone the body normally makes. It is also used to treat certain types of thyroid cancer and [&hellip;]<\/p>\n","protected":false},"author":133,"featured_media":628829,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[3896],"coauthors":[10668],"class_list":["post-628828","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-thyroid","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>How long does it take for levothyroxine to work?<\/title>\n<meta name=\"description\" content=\"Levothyroxine starts to work immediately for thyroid disease, but may take up to six weeks for you to notice the full benefits. Learn tips for taking levothyroxine.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.singlecare.com\/blog\/how-long-does-it-take-for-levothyroxine-to-work\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"How long does it take levothyroxine to work?\" \/>\n<meta property=\"og:description\" content=\"Levothyroxine starts to work immediately for thyroid disease, but may take up to six weeks for you to notice the full benefits. 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