{"id":628905,"date":"2024-07-10T09:15:13","date_gmt":"2024-07-10T13:15:13","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=628905"},"modified":"2025-02-19T15:52:56","modified_gmt":"2025-02-19T20:52:56","slug":"taking-wegovy-for-the-first-time","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/taking-wegovy-for-the-first-time\/","title":{"rendered":"Taking Wegovy for the first time: Tips and more"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">If you\u2019ve considered taking Ozempic for weight management but discovered it\u2019s only approved by the Food and Drug Administration (FDA) for the treatment of Type 2 diabetes, there is another possible option: <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/wegovy\"><span style=\"font-weight: 400;\">Wegovy<\/span><\/a><span style=\"font-weight: 400;\">. It\u2019s similar to Ozempic both in how it\u2019s administered (by injection) and its active ingredient (semaglutide). But, <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/wegovy-vs-ozempic\/\"><span style=\"font-weight: 400;\">unlike Ozempic<\/span><\/a><span style=\"font-weight: 400;\">, Wegovy is FDA approved for chronic weight management in certain populations, including people 12 years and older who meet specific body mass index (BMI) requirements or have other health conditions affecting their cardiovascular health.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The recent popularity of injectable weight loss drugs has given many people a sense of familiarity with them, but it can still feel intimidating when you\u2019re sent home with your first dose of <a href=\"https:\/\/www.singlecare.com\/prescription\/wegovy\/what-is\">Wegovy<\/a>. While your healthcare provider or pharmacist will likely have talked to you about how to self-administer Wegovy, you may have more questions about what you can expect after taking your first dose. Here\u2019s everything you need to know to get started with your first dose of Wegovy, from where to inject it and what it will feel like to when you can expect results (and potential side effects).<\/span><\/p>\n<h2 id=\"how-to-use-the-wegovy-pen\"><span style=\"font-weight: 400;\">How to use the Wegovy pen<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Wegovy comes in a single-use pen that is pre-loaded with your dose. According to <\/span><a href=\"https:\/\/www.medicalofficesofmanhattan.com\/our-team\/jared-braunstein-do\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Jared Braunstein, DO<\/span><\/a><span style=\"font-weight: 400;\">, an internist with Medical Offices of Manhattan and contributor to LabFinder, the usual starting dose of Wegovy is 0.25 milligrams (mg) once a week. <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/can-i-start-wegovy-at-2-4-mg\/\"><span style=\"font-weight: 400;\">Starting at a higher dose <\/span><\/a><span style=\"font-weight: 400;\">isn\u2019t advised, because your body needs time to adjust to the medication.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">It\u2019s important to follow the instructions your healthcare provider or pharmacist has given you about injecting yourself with the Wegovy pen. Your prescription should also come with detailed instructions for use, and Wegovy\u2019s manufacturer, Novo Nordisk, has <\/span><a href=\"https:\/\/www.wegovy.com\/taking-wegovy\/how-to-use-the-wegovy-pen.html\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">this information (and a helpful instructional video)<\/span><\/a><span style=\"font-weight: 400;\"> on its website for further reference. Wegovy should be kept refrigerated until use or kept at room temperature in its carton for a maximum of 28 days. \u201cYou can take it with or without food,\u201d says Dr. Braunstein. Be mindful of the medication\u2019s environment. Do not let the medication freeze or stay in a hot car or mailbox.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Per Novo Nordisk, the basic steps for using the Wegovy pen are as follows:<\/span><\/p>\n<ol>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Wash your hands.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Inspect your pen for defects, including cracks on the outside of the pen or discolored medication inside the pen. Check that the expiration date has not passed.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Choose an injection site (if you need more help, read more about <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/wegovy-injection-site\/\"><span style=\"font-weight: 400;\">where and how to inject Wegovy<\/span><\/a><span style=\"font-weight: 400;\">), and clean the injection site with rubbing alcohol or soap and water. Pat the area dry.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Remove the medication\u2019s pen cap.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Place the pen against the injection site and press down to get the yellow injection bar moving. You will hear two clicks during this process. Once the yellow bar has stopped moving, the injection is complete, and you can slowly lift the pen away from your skin.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dispose of the pen in an FDA-approved <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/sharps-container\"><span style=\"font-weight: 400;\">sharps container<\/span><\/a><span style=\"font-weight: 400;\"> (or acceptable alternative) and gently dab any blood at the injection site with a cotton pad or ball.\u00a0\u00a0<\/span><\/li>\n<\/ol>\n<p><span style=\"font-weight: 400;\">\t\t<div class=\"singlecare-dynamic-newsletter-wrapper sin-newsletter-wrapper\">\n\t\t\t<span class=\"heading\">Get our weight management newsletter<\/span>\n\t\t\t<form class=\"form-wrapper\" data-newsletter-form=\"1\" data-subsource=\"Weight Management Newsletter\">\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<label for=\"dynamic-email\">Email<\/label>\n\t\t\t\t\t<input type=\"email\" id=\"dynamic-email\" class=\"email\" required>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<input class=\"submit-form-btn\" type=\"submit\" value=\"Click to sign up\">\n\t\t\t\t<\/div>\n\t\t\t<\/form>\n\t\t\t<p class=\"success-message\" aria-live=\"polite\"><\/p>\n\t\t<\/div>\n\t<\/span><\/p>\n<h2 id=\"what-to-expect-the-first-time-taking-wegovy\"><span style=\"font-weight: 400;\">What to expect the first time taking Wegovy<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The first time you take Wegovy, you shouldn\u2019t expect anything noticeable to happen. That may change quickly, however, as side effects usually kick in within the first few days after a dose. Here\u2019s what to expect.\u00a0\u00a0<\/span><\/p>\n<h3 id=\"what-are-the-first-day-side-effects-of-wegovy\"><span style=\"font-weight: 400;\">What are the first-day side effects of Wegovy?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The majority of Wegovy side effects don\u2019t start on the first day. Dr. Braunstein says most people don\u2019t feel anything right away, which means you don\u2019t need to plan your life around your first Wegovy dose: You can drive, go to work, eat normally, and otherwise go about your normal routine. Over time, <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/does-wegovy-make-you-tired\/\"><span style=\"font-weight: 400;\">Wegovy may cause some fatigue<\/span><\/a><span style=\"font-weight: 400;\">, but don\u2019t expect it to happen suddenly.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cThe only side effect you might experience on the first day is injection-site irritation, such as redness, swelling, and itching,\u201d says <\/span><a href=\"https:\/\/www.lightningvip.com\/about-us\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Alexandria Lightning, DNP<\/span><\/a><span style=\"font-weight: 400;\">, founder of Lightning VIP. Irritation at the injection site typically decreases with continued use.<\/span><\/p>\n<h3 id=\"common-wegovy-side-effects-first-weeks-and-beyond\"><span style=\"font-weight: 400;\">Common Wegovy side effects: First weeks and beyond<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">While you will probably feel totally normal on your first day taking Wegovy, Dr. Lightning says that side effects usually begin within the first few days after a dose and may include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea and vomiting, especially when starting or increasing the medication<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Gastrointestinal issues like diarrhea and constipation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Abdominal pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Indigestion<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fatigue<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Headache<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Decreased appetite<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Wegovy works as a weight loss treatment because it suppresses your appetite, Dr. Lightning notes, so a noticeable decrease in hunger is counted among the early symptoms of taking the drug. As you move beyond the first few weeks, that decreased appetite should start leading to sustained weight loss. In fact, in <\/span><a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2032183\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">a double-blind clinical trial of people who took semaglutide over 68 weeks<\/span><\/a><span style=\"font-weight: 400;\">, 69% of participants lost at least 10% of their body weight within 68 weeks of taking Wegovy, and 50.5% lost at least 15%.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cThere may also be other health benefits observed with long-term use of Wegovy,\u201d Dr. Lightning says, \u201cincluding better blood sugar control and a <\/span><a href=\"https:\/\/www.fda.gov\/news-events\/press-announcements\/fda-approves-first-treatment-reduce-risk-serious-heart-problems-specifically-adults-obesity-or\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">lower risk of cardiovascular events<\/span><\/a><span style=\"font-weight: 400;\">.\u201d<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/how-long-does-wegovy-stay-in-your-system\/\"><b>How long does Wegovy stay in your system?<\/b><\/a><\/p>\n<h3 id=\"serious-wegovy-side-effects\"><span style=\"font-weight: 400;\">Serious Wegovy side effects<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">More serious side effects of Wegovy are rare but possible, so it\u2019s important to know what to look for throughout the course of treatment. If you experience any serious side effects, contact your healthcare provider right away or go to the nearest emergency care center, as some of these could be signs of a life-threatening medical condition.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">According to Dr. Lightning, these are the serious side effects to be especially aware of when taking Wegovy:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Inflammation of the pancreas, or <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/pancreatitis-treatment-and-medications\"><span style=\"font-weight: 400;\">pancreatitis<\/span><\/a><span style=\"font-weight: 400;\">, which may appear at first as a fever and severe abdominal pain below the breastbone (that can radiate to the back)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Gallstones, especially if you\u2019ve had significant weight loss while taking it. Gallstones may feel like right-upper-quadrant abdominal pain that worsens after a fatty meal.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dehydration and other kidney issues as a result of gastrointestinal side effects like vomiting<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hypoglycemia, or low blood sugar, which is more common in people with Type 2 diabetes taking other medications that lower blood sugar<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Severe allergic reaction, which may appear as difficulty breathing or swelling of the face, lips, tongue, or throat\u00a0<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Again, these side effects are not common, but they are potentially dangerous. Don\u2019t hesitate to seek medical attention if you\u2019re experiencing any of them. <\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/wegovy-results\/\"><b>Wegovy results: First month and beyond<\/b><\/a><span style=\"font-weight: 400;\"> \u2502 <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/how-quickly-does-wegovy-work\/\"><b>How quickly does Wegovy work?<\/b><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>If you\u2019ve considered taking Ozempic for weight management but discovered it\u2019s only approved by the Food and Drug Administration (FDA) for the treatment of Type 2 diabetes, there is another possible option: Wegovy. It\u2019s similar to Ozempic both in how it\u2019s administered (by injection) and its active ingredient (semaglutide). But, unlike Ozempic, Wegovy is FDA [&hellip;]<\/p>\n","protected":false},"author":149,"featured_media":628907,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[4343,21067,9825],"coauthors":[8860],"class_list":["post-628905","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-brand-name-drugs","tag-glp-1-drugs","tag-weight-loss","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Taking Wegovy for the first time: Tips and more<\/title>\n<meta name=\"description\" content=\"Knowing what to expect when taking Wegovy for the first time can make the injection process easier than you may think.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, 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