{"id":628930,"date":"2024-07-10T16:21:11","date_gmt":"2024-07-10T20:21:11","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=628930"},"modified":"2026-03-03T17:40:18","modified_gmt":"2026-03-03T22:40:18","slug":"omeprazole-dosage-for-dogs","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/omeprazole-dosage-for-dogs\/","title":{"rendered":"How much omeprazole can I give my dog?"},"content":{"rendered":"

Omeprazole<\/span><\/a> (brand name Prilosec) is a potent drug that reduces stomach acid. It\u2019s familiar to most people as a <\/span>heartburn<\/span><\/a>, <\/span>GERD<\/span><\/a>, or <\/span>ulcer medication<\/span><\/a>. Veterinarians use omeprazole in dogs to treat stomach ulcers, duodenal ulcers, <\/span>gastritis<\/span><\/a>, and other erosive conditions in the stomach or esophagus. When your dog is prescribed omeprazole, you will typically give once-daily doses of 0.5 to 1 mg per kilogram of body weight, though veterinarians may sometimes prescribe twice-daily doses.<\/span><\/p>\n\t\t

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RELATED: <\/b>Omeprazole for dogs: dosage and safety<\/b><\/a><\/p>\n

Omeprazole dosage for dogs<\/span><\/h2>\n

\u201cThe dosage of omeprazole for dogs depends on the severity of the condition, what condition is being treated, other underlying conditions, the weight of the dog, and if the dog is on any other medications,\u201d says <\/span>Dwight Alleyne, DVM<\/span><\/a>, a veterinarian adviser for <\/span>Betterpet.com<\/span><\/a>.<\/span><\/p>\n

Below are a few medical conditions in which a veterinarian may prescribe omeprazole.<\/span><\/p>\n

Stomach ulcers<\/span><\/h3>\n

Stomach or gastrointestinal ulcers are open sores in <\/span>the stomach lining<\/span><\/a> that can develop from kidney disease, non-steroidal anti-inflammatory drugs (<\/span>NSAIDs<\/span><\/a>), or cancer, such as gastrinomas. These ulcers can cause symptoms like vomiting, anorexia, abdominal pain, and weight loss.\u00a0<\/span><\/p>\n

According to <\/span>Ray Spragley, DVM, CVA, CCRT<\/span><\/a>, the founder of <\/span>Zen Dog Veterinary Care<\/span><\/a>, the typical omeprazole dosage for preventing or treating stomach ulcers is 0.5 mg\/kg once daily by mouth. Doses can go as high as 1 mg\/kg per day.<\/span><\/p>\n

Esophagitis<\/span><\/h3>\n

Esophagitis<\/span><\/a> is a condition that <\/span>causes inflammation<\/span><\/a> in your dog\u2019s esophagus. It can arise from foreign bodies, GERD, and certain drugs, such as <\/span>doxycycline<\/span><\/a>.\u00a0<\/span><\/p>\n

Dr. Spragley recommends 1-2 mg\/kg twice daily by mouth to treat esophagitis in dogs. Veterinarians may prescribe a lower dose for mild or moderate esophagitis.<\/span><\/p>\n

Helicobacter\u00a0<\/span><\/h3>\n

Helicobacter is a type of bacteria that can infect your dog\u2019s stomach. In humans, a type of Helicobacter, H. pylori, has been linked to stomach irritation and ulcers. While <\/span>Helicobacter bacteria<\/span><\/a> are commonly found in dog and cat stomachs, the link between these bacteria and symptoms of stomach ulceration or irritation is not fully understood at this time. Veterinarians may still use omeprazole to reduce stomach acid as part of a medication protocol for treating Helicobacter infections.<\/span><\/p>\n

According to Dr. Spragley, a dose of 0.7 mg\/kg once daily by mouth is recommended for Helicobacter treatment.<\/span><\/p>\n

The duration of treatment with omeprazole depends on the condition your dog is being treated for. \u201cOmeprazole is usually prescribed short-term,\u201d Dr. Spragley says. \u201cOmeprazole is safe to be given long-term, but is usually only given for up to four weeks.\u201d<\/span><\/p>\n

Dr. Alleyne adds that long-term omeprazole use may be appropriate for some dogs with chronic conditions, but they will need to be monitored closely for potential side effects.\u00a0<\/span><\/p>\n

How much omeprazole can I give my dog?<\/span><\/h2>\n

Amanda Chambers, DVM<\/span><\/a>, a veterinary consultant for <\/span>Embrace Pet Insurance<\/span><\/a>, says the recommended omeprazole dosage for dogs is 0.5 to 1 milligrams (mg) per kilogram of body weight by mouth every 12 to 24 hours. To determine the proper dose of omeprazole to administer to your dog, you\u2019ll first need to know your dog\u2019s weight. From there, says Dr. Chambers, you can calculate how much medicine you need to give your pet:<\/span><\/p>\n

\u201cFirst, convert your pet’s weight to kilograms. This is done by dividing your pet\u2019s weight in pounds by 2.2. Once you have their weight in kilograms, multiply this number by 0.5 milligrams and 1 milligram to get the recommended range of milligrams to administer every 12 to 24 hours. Round to the nearest 5 milligrams.\u201d<\/span>
\n<\/span><\/p>\n

In most cases, you won\u2019t need to calculate your dog\u2019s omeprazole dosage on your own. Typically, your dog\u2019s vet will handle any calculations to ensure your dog has the proper dose to relieve their symptoms. \u201cWhen it comes to calculating dosages, pet owners should always refer to their veterinarian to prevent under- or overdosing,\u201d Dr. Alleyne says.<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\n

Omeprazole for dogs dosage chart by weight<\/span><\/h2>\n<\/th>\n<\/tr>\n<\/thead>\n

Weight<\/b><\/td>\nDosage<\/b><\/td>\n<\/tr>\n
5-9 lbs.<\/span><\/td>\n2.5 mg<\/span><\/td>\n<\/tr>\n
10-14 lbs.<\/span><\/td>\n5 mg<\/span><\/td>\n<\/tr>\n
15-46 lbs.<\/span><\/td>\n10 mg<\/span><\/td>\n<\/tr>\n
47-56 lbs.<\/span><\/td>\n15 mg<\/span><\/td>\n<\/tr>\n
57-80 lbs.<\/span><\/td>\n20 mg<\/span><\/td>\n<\/tr>\n
81-87 lbs.<\/span><\/td>\n25 mg<\/span><\/td>\n<\/tr>\n
88-105 lbs.<\/span><\/td>\n30 mg<\/span><\/td>\n<\/tr>\n
106-115 lbs.<\/span><\/td>\n35 mg<\/span><\/td>\n<\/tr>\n
116-130 lbs.<\/span><\/td>\n40 mg<\/span><\/td>\n<\/tr>\n
131-150 lbs.<\/span><\/td>\n45 mg<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Source: <\/span>Media City Animal Hospital<\/span><\/a><\/p>\n

For your dog\u2019s doses, you may need to divide the pills, since omeprazole comes in 10 mg and 20 mg strengths. The veterinarian can supply omeprazole from a compounding pharmacy in a dosage strength as low as 5 mg, but you may still need to cut the pills in half for very small dogs. If you don\u2019t know the proper procedure for dividing tablets, have the veterinarian or a veterinary tech demonstrate.<\/span><\/p>\n

Does omeprazole interact with any other dog medications?<\/span><\/h2>\n

Be sure to notify your veterinarian of all your dog\u2019s prescription medications so that they can determine if prescribing omeprazole is safe. Certain medications can interact with omeprazole. \u201cSome drugs it interacts with are phenobarbital, <\/span>diuretics<\/span><\/a>, digoxin, cyclosporine, benzodiazepines, clopidogrel, cyanocobalamin, levothyroxine, warfarin, and certain <\/span>antibiotics<\/span><\/a>,\u201d Dr. Spragley says.<\/span>
\n<\/span>Like any prescription medication, there are some side effects of omeprazole.<\/span><\/p>\n

\u201cCommon adverse effects of omeprazole include diarrhea, vomiting, and decreased appetite,\u201d Dr. Alleyne says. \u201cIf these are seen, the drug should be discontinued, and a veterinarian should be contacted.\u201d<\/span>
\n<\/span>While omeprazole is typically well-tolerated, the effects of long-term use of omeprazole are still not fully understood. Omeprazole falls under a class of drugs known as proton pump inhibitors (<\/span>PPIs<\/span><\/a>). Research shows that while PPIs are generally <\/span>safe in short courses<\/span><\/a>, decisions to use these drugs long-term should be made with caution and with consideration of other medications the pet is taking to avoid drug interactions.<\/span>\u00a0<\/span><\/p>\n

Omeprazole should also be <\/span>avoided or used with caution<\/span><\/a> in dogs who have liver or kidney disease, are pregnant, or are nursing.\u00a0<\/span><\/p>\n

RELATED: <\/b>Discount pet meds<\/b><\/a><\/p>\n

Guidelines for administering omeprazole in dogs<\/span><\/h2>\n

Dr. Chambers recommends pet owners give their dogs omeprazole on an empty stomach in the morning. \u201cThis allows for quick absorption and acid reduction and will hopefully manage nausea that may otherwise potentially cause vomiting after a meal.\u201d<\/span><\/p>\n

Dr. Alleyne adds that you can give omeprazole to your dog about 30 minutes before their first meal of the day. If your dog vomits while taking the medicine on an empty stomach, you can give future doses with food.<\/span>
\n<\/span><\/p>\n

It\u2019s not uncommon to forget to give a dose of medication to your dog. If you miss a dose of omeprazole, Dr. Chambers says to go ahead and give your dog the dose if it is within a few hours of the scheduled time. \u201cIf the missed dose is not realized until a few hours from the next scheduled dose, consider waiting until that dose is due,\u201d Dr. Chambers adds.<\/span><\/p>\n

If you\u2019re unsure what to do, you can contact your veterinarian for guidance on administering the next dose of omeprazole.\u00a0<\/span><\/p>\n

When you may need to stop giving your dog omeprazole, Dr. Spragley says the medication clears quickly from your dog\u2019s bloodstream. \u201cThe drug’s half-life is only one hour in dogs,\u201d Dr. Spragley says. \u201cThe effects of omeprazole\u2019s antisecretory effect can last up to three to four days from a single dose, even though it is no longer present in the bloodstream.\u201d<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Omeprazole (brand name Prilosec) is a potent drug that reduces stomach acid. It\u2019s familiar to most people as a heartburn, GERD, or ulcer medication. Veterinarians use omeprazole in dogs to treat stomach ulcers, duodenal ulcers, gastritis, and other erosive conditions in the stomach or esophagus. When your dog is prescribed omeprazole, you will typically give […]<\/p>\n","protected":false},"author":133,"featured_media":628931,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[7956],"tags":[7969],"coauthors":[20975],"class_list":["post-628930","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pets","tag-dogs","wpautop"],"acf":[],"yoast_head":"\nOmeprazole dosage for dogs: What you should know<\/title>\n<meta name=\"description\" content=\"The recommended omeprazole dosage for dogs is 0.5 to 1 mg per kilogram of body weight. 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