{"id":629061,"date":"2024-08-12T09:30:14","date_gmt":"2024-08-12T13:30:14","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=629061"},"modified":"2026-05-01T10:37:27","modified_gmt":"2026-05-01T14:37:27","slug":"farxiga-weight-loss","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/farxiga-weight-loss\/","title":{"rendered":"Does Farxiga cause weight loss?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Nearly half of U.S. adults want to lose weight<\/span><span style=\"font-weight: 400;\">, and many are looking for solutions that can aid them in their journey. Some are turning to <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/farxiga\"><span style=\"font-weight: 400;\">Farxiga (dapagliflozin)<\/span><\/a><span style=\"font-weight: 400;\">, a Type 2 diabetes drug that can cause weight loss as a side effect. This medication improves blood glucose levels by removing excess sugar from the body. <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/farxiga\/what-is\"><span style=\"font-weight: 400;\">Farxiga<\/span><\/a><span style=\"font-weight: 400;\"> also can reduce the risk of hospitalization from heart failure and slow down kidney disease progression in patients with chronic renal disease.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">However, experts say taking Farxiga <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/off-label-prescription-drugs\/\"><span style=\"font-weight: 400;\">off-label<\/span><\/a><span style=\"font-weight: 400;\"> for weight loss isn\u2019t for everyone. Here\u2019s what you need to know about how the medication works, how much weight you may lose, and whether it\u2019s the right option for you.<\/span><\/p>\n\t\t<div id=\"coupon-cta\" class=\"coupon-cta master-template\">\n\t\t\t<p id=\"headline\">Save up to 80% on Farxiga with SingleCare<\/p>\n\t\t\t<p id=\"subheadline\">Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t<div class=\"details-wrap\">\n\t\t\t\t<div class=\"details\">\n\t\t\t\t\tFarxiga 10 mg (30 tablets)\t\t\t\t<\/div>\n\t\t\t\t<div class=\"address\">\n\t\t\t\t\t23663 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"api-response\">\n\t\t\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-food-lion.svg\" alt=\"Food Lion\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$40.70<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/farxiga#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/farxiga#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-cvs.svg\" alt=\"CVS Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$207.43<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/farxiga#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/farxiga#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/farxiga#blog-cta\" class=\"coupon-see-all-btn\">See Farxiga prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n<h2 id=\"does-farxiga-cause-weight-loss\"><span style=\"font-weight: 400;\">Does Farxiga cause weight loss?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">One possible side effect of Farxiga (dapagliflozin) is weight loss. However, the U.S. Food and Drug Administration (FDA) has not approved Farxiga as a <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/best-weight-loss-pills\/\"><span style=\"font-weight: 400;\">weight-loss medication<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Rather, Farxiga is an FDA-approved treatment for Type 2 diabetes mellitus. This drug helps to control blood sugar levels and reduce the <\/span><a href=\"https:\/\/www.fda.gov\/news-events\/press-announcements\/fda-approves-new-treatment-type-heart-failure\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">risk of heart failure<\/span><\/a><span style=\"font-weight: 400;\">. The medication is also used to help slow down the progression of <\/span><a href=\"https:\/\/www.fda.gov\/news-events\/press-announcements\/fda-approves-treatment-chronic-kidney-disease\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">chronic kidney disease<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Because Farxiga can cause weight loss as a side effect, the drug has been used off-label for weight management. <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2022\/202293s028lbl.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Clinical studies<\/span><\/a><span style=\"font-weight: 400;\"> show that people who took Farxiga for 24 weeks lost up to seven pounds (just over three kilograms). <\/span><a href=\"https:\/\/link.springer.com\/article\/10.1007\/s40265-019-01148-3\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Another study<\/span><\/a><span style=\"font-weight: 400;\"> of patients with Type 2 diabetes and heart disease found that Farxiga led to an average of six pounds lost within one year of starting the medication.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Experts believe that Farxiga sends extra glucose, or sugar, from blood to the urine. Calories from the glucose then leave the body in the urine. \u201cThe studies show that glucose output from medications like Farxiga is equal to about 300 calories per day,\u201d says <\/span><a href=\"https:\/\/www.linkedin.com\/in\/briee-landis\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Briee Kulesa, Pharm.D.<\/span><\/a><span style=\"font-weight: 400;\">, a clinical pharmacist with <\/span><a href=\"https:\/\/www.franciscanhealth.org\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Franciscan Health<\/span><\/a><span style=\"font-weight: 400;\">. \u201cThis reduction in calories as well as fluid volume reduction from urine contributes to weight loss.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">While lifestyle factors like a healthy diet, exercise, other medications, and genetics can contribute to weight loss, Dr. Kulesa says the average person can expect to lose three to ten pounds while taking Farxiga.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\t\t<div class=\"singlecare-dynamic-newsletter-wrapper sin-newsletter-wrapper\">\n\t\t\t<span class=\"heading\">Get our weight management newsletter<\/span>\n\t\t\t<form class=\"form-wrapper\" data-newsletter-form=\"1\" data-subsource=\"Weight Management Newsletter\">\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<label for=\"dynamic-email\">Email<\/label>\n\t\t\t\t\t<input type=\"email\" id=\"dynamic-email\" class=\"email\" required>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<input class=\"submit-form-btn\" type=\"submit\" value=\"Click to sign up\">\n\t\t\t\t<\/div>\n\t\t\t<\/form>\n\t\t\t<p class=\"success-message\" aria-live=\"polite\"><\/p>\n\t\t<\/div>\n\t<\/span><\/p>\n<h2 id=\"how-does-farxiga-work-for-weight-loss\"><span style=\"font-weight: 400;\">How does Farxiga work for weight loss?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Farxiga belongs to a family of medications called <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/sglt2-inhibitors\"><span style=\"font-weight: 400;\">SGLT2 inhibitors<\/span><\/a><span style=\"font-weight: 400;\">, or sodium-glucose co-transporter 2 inhibitors. Healthcare providers use these medications to treat conditions like Type 2 diabetes mellitus, heart failure, and chronic kidney disease.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The active ingredient in Farxiga, dapagliflozin, blocks the SGLT2 protein in the kidneys from doing its job\u2014reabsorbing glucose into the bloodstream, says <\/span><a href=\"https:\/\/www.thehcginstitute.com\/doctors\/danielle-kelvas-md\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Danielle Kelvas<\/span><\/a><span style=\"font-weight: 400;\">, MD, a primary care provider with the <\/span><a href=\"https:\/\/www.thehcginstitute.com\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">HCG Institute<\/span><\/a><span style=\"font-weight: 400;\">, a telemedicine weight loss company.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">By blocking this process, dapagliflozin causes excess sugar to leave the body through the urine, aiding in weight loss and improved blood pressure. \u201cWhile not officially sanctioned for weight loss, its mechanism contributes to weight reduction, marking it as a noteworthy off-label option for this purpose,\u201d Dr. Kelvas explains.<\/span><\/p>\n<h2 id=\"how-fast-does-farxiga-cause-weight-loss\"><span style=\"font-weight: 400;\">How fast does Farxiga cause weight loss?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">When patients first begin taking <\/span><span style=\"font-weight: 400;\">Farxiga<\/span><span style=\"font-weight: 400;\">, they may initially lose weight thanks to the need to urinate more frequently, Dr. Kulesa says.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">A healthcare study published in <\/span><a href=\"https:\/\/cardiab.biomedcentral.com\/articles\/10.1186\/s12933-019-0852-y\" target=\"_blank\" rel=\"noopener\"><i><span style=\"font-weight: 400;\">Cardiovascular Diabetology<\/span><\/i><\/a><span style=\"font-weight: 400;\"> found that participants noticed a drop in body weight within just three days. Any weight lost in the first month when on drugs like Farxiga is often from fluid loss, commonly known as water weight, says <\/span><a href=\"https:\/\/www.drugwatch.com\/contributors\/shannon-fitzgerald-pharmd\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Shannon Fitzgerald<\/span><\/a><span style=\"font-weight: 400;\">, Pharm.D., a medical expert with Drugwatch. \u201cA reduction in body weight is usually noticed in the first two to four weeks, typically water loss, with a fat reduction noticed by six weeks,\u201d Dr. Fitzgerald said.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">When people lose weight in general, they may lose fat, muscle, water, or other body elements. \u201cThe body holds on to fat and water in different ways,\u201d Dr. Kulesa explains. \u201cFat loss often occurs more slowly and gradually, whereas water loss often occurs more rapidly and fluctuates more. Both can be affected by diet and medications, among other factors.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\t\t<div class=\"singlecare-dynamic-newsletter-wrapper sin-newsletter-wrapper\">\n\t\t\t<span class=\"heading\">Get our diabetes newsletter<\/span>\n\t\t\t<form class=\"form-wrapper\" data-newsletter-form=\"1\" data-subsource=\"Diabetes Newsletter\">\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<label for=\"dynamic-email\">Email<\/label>\n\t\t\t\t\t<input type=\"email\" id=\"dynamic-email\" class=\"email\" required>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<input class=\"submit-form-btn\" type=\"submit\" value=\"Click to sign up\">\n\t\t\t\t<\/div>\n\t\t\t<\/form>\n\t\t\t<p class=\"success-message\" aria-live=\"polite\"><\/p>\n\t\t<\/div>\n\t<\/span><\/p>\n<h2 id=\"who-should-not-take-farxiga\"><span style=\"font-weight: 400;\">Who should not take Farxiga?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">While Farxiga offers some benefits, such as weight loss, blood sugar level control, and heart failure prevention, it\u2019s not suitable for everyone. People with a history of certain medical conditions should not take Farxiga, such as:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Type 1 diabetes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Genital yeast infections<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Urinary tract infections (UTIs)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Chronic kidney disease (CKD) that requires dialysis<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">History of bariatric surgery, including gastric bypass and sleeve gastrectomy surgery<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Diabetic ketoacidosis is a medical condition where the body can\u2019t produce enough insulin and can increase ketones in the blood or urine. <\/span><a href=\"https:\/\/www.farxiga.com\/side-effects\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Farxiga can cause ketoacidosis<\/span><\/a><span style=\"font-weight: 400;\"> to occur, which can be a serious side effect that is life-threatening.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">This medication should be used with caution if a patient is also taking:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diuretics, like hydrochlorothiazide<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Other glucose-lowering medications like sulfonylureas<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lithium<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">In addition to weight loss and ketoacidosis, <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/farxiga-side-effects\/\"><span style=\"font-weight: 400;\">common side effects<\/span><\/a><span style=\"font-weight: 400;\"> include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dehydration<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Urinary tract infections<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hypoglycemia (low blood sugar)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Bacterial infections<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Yeast infections<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Constipation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Back pain<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Using Farxiga for long-term weight management isn\u2019t recommended. \u201cOur kidneys work hard to keep our fluid in balance, and this includes electrolytes,\u201d Dr. Kelvas says. \u201cUrinating sugar long-term can really negatively impact the kidneys. That\u2019s why when we prescribe these drugs, it\u2019s always with the goal of eventually coming off of them and getting on more ideal long-term drugs like metformin.\u201d Other Farxiga alternatives for weight loss are glucagon-like peptide-1 (GLP-1) agonists, such as <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/wegovy\"><span style=\"font-weight: 400;\">Wegovy (semaglutide)<\/span><\/a><span style=\"font-weight: 400;\"> or <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/saxenda\"><span style=\"font-weight: 400;\">Saxenda (liraglutide)<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h2 id=\"the-bottom-line-farxiga-can-cause-weight-loss\"><span style=\"font-weight: 400;\">The bottom line: Farxiga can cause weight loss<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Patients who take Farxiga may experience weight loss within the first few weeks of starting the drug. Yet studies show patients may only experience a weight loss of about seven pounds over the course of six months.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">While losing weight is a common side effect of Farxiga,\u00a0 Dr. Kelvas says she does not recommend this drug for long-term weight management. It\u2019s also important to seek medical advice from a healthcare professional to create an individualized weight management plan. Make sure the healthcare provider is aware of any current prescription drugs, over-the-counter drugs, and dietary supplements you take to help avoid serious side effects.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cI tell patients that there is no single magic bullet medication that you can take to make fat melt away,\u201d Dr. Kelvas says. \u201cIt has to be combined with overall lifestyle changes, like improving your diet and exercise.\u201d<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nearly half of U.S. adults want to lose weight, and many are looking for solutions that can aid them in their journey. Some are turning to Farxiga (dapagliflozin), a Type 2 diabetes drug that can cause weight loss as a side effect. This medication improves blood glucose levels by removing excess sugar from the body. [&hellip;]<\/p>\n","protected":false},"author":135,"featured_media":629232,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[10298,788,9825],"coauthors":[21050],"class_list":["post-629061","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-diabetes","tag-drug-safety","tag-weight-loss","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Does Farxiga cause weight loss?<\/title>\n<meta name=\"description\" content=\"Learn how Farxiga affects body weight, potential benefits, and what to expect. 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