{"id":629392,"date":"2024-08-26T09:30:40","date_gmt":"2024-08-26T13:30:40","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=629392"},"modified":"2025-10-20T19:57:02","modified_gmt":"2025-10-20T23:57:02","slug":"does-gabapentin-cause-weight-gain","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/does-gabapentin-cause-weight-gain\/","title":{"rendered":"Does gabapentin cause weight gain?"},"content":{"rendered":"<p><a href=\"https:\/\/www.singlecare.com\/prescription\/gabapentin\/what-is\"><span style=\"font-weight: 400;\">Gabapentin<\/span><\/a><span style=\"font-weight: 400;\"> (brand name <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/neurontin\"><span style=\"font-weight: 400;\">Neurontin<\/span><\/a><span style=\"font-weight: 400;\">) is an anti-seizure medication that is primarily used to alleviate nerve pain and manage seizures. The prescription drug is <\/span><a href=\"https:\/\/www.health.harvard.edu\/staying-healthy\/gabapentin-uses-side-effects-and-what-you-should-know-if-youve-been-prescribed-this-medication\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">FDA approved<\/span><\/a><span style=\"font-weight: 400;\"> to control seizures in adults and children with epilepsy and treat a type of nerve pain called<\/span><span style=\"font-weight: 400;\"> postherpetic neuralgia (PHN) that can occur after a shingles infection. It\u2019s also used off-label to treat diabetic neuropathy, fibromyalgia, neuropathic pain from sciatica, alcohol dependence, and anxiety<\/span><span style=\"font-weight: 400;\">. An extended-release form of gabapentin is approved to treat restless legs syndrome.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Because it\u2019s effective for many different nervous system and chronic pain disorders, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/gabapentin\"><span style=\"font-weight: 400;\">gabapentin<\/span><\/a><span style=\"font-weight: 400;\"> is commonly prescribed. But like all medications, gabapentin comes with the possibility of side effects, including one that may surprise you\u2014weight gain. Here\u2019s what to know if your weight changes on gabapentin.<\/span><\/p>\n<h2 id=\"can-gabapentin-cause-weight-gain\"><span style=\"font-weight: 400;\">Can gabapentin cause weight gain?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">In <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2017\/020235s064_020882s047_021129s046lbl.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">clinical trials<\/span><\/a><span style=\"font-weight: 400;\">, the most common side effects of gabapentin in adults were drowsiness, dizziness, and edema (fluid retention) in the legs, feet, arms, and hands. While it\u2019s not a common side effect, about 2% of patients taking gabapentin experienced weight gain, and 8% experienced fluid retention. <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/gabapentin-side-effects\/\"><span style=\"font-weight: 400;\">Other potential side effects<\/span><\/a><span style=\"font-weight: 400;\"> include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Uncontrolled eye movements<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tremors<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Weakness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diarrhea or constipation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dry mouth<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Infection<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sore throat<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cough<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Upset stomach, nausea, or vomiting<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Loss of coordination<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Blurred or double vision<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lazy eye<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Depression<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Memory problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Weight gain<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Serious side effects of gabapentin include suicidal thoughts and behaviors, muscle damage, slow breathing, withdrawal symptoms (if the medicine is stopped abruptly or too quickly), and severe allergic or skin reactions. Seek immediate medical attention if you experience any of these rare but possible side effects.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">This is not a full list of side effects, and others may occur. Consult your healthcare provider for more information about the potential side effects of gabapentin.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\t\t<div class=\"singlecare-dynamic-newsletter-wrapper sin-newsletter-wrapper\">\n\t\t\t<span class=\"heading\">Get our weight management newsletter<\/span>\n\t\t\t<form class=\"form-wrapper\" data-newsletter-form=\"1\" data-subsource=\"Weight Management Newsletter\">\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<label for=\"dynamic-email\">Email<\/label>\n\t\t\t\t\t<input type=\"email\" id=\"dynamic-email\" class=\"email\" required>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<input class=\"submit-form-btn\" type=\"submit\" value=\"Click to sign up\">\n\t\t\t\t<\/div>\n\t\t\t<\/form>\n\t\t\t<p class=\"success-message\" aria-live=\"polite\"><\/p>\n\t\t<\/div>\n\t<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/gabapentin-interactions\/\"><b>Gabapentin interactions to avoid<\/b><\/a><\/p>\n<p><span style=\"font-weight: 400;\">But exactly how does gabapentin cause <a href=\"https:\/\/www.singlecare.com\/\/blog\/rapid-weight-gain-causes\">weight gain<\/a>? According to <\/span><a href=\"https:\/\/www.linkedin.com\/in\/sazan-sylejmani-a6ba1080\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Sazan Sylejmani, Pharm.D.<\/span><\/a><span style=\"font-weight: 400;\">, owner and pharmacy manager at <\/span><a href=\"https:\/\/www.westmontpharmacy.com\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Westmont Pharmacy<\/span><\/a><span style=\"font-weight: 400;\"> in Illinois, <\/span><span style=\"font-weight: 400;\">gabapentin can affect your waistline by impacting:<\/span><\/p>\n<ol>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Appetite:<\/b><span style=\"font-weight: 400;\"> One of the most significant ways gabapentin can cause weight gain is by <\/span><a href=\"https:\/\/www.nhs.uk\/medicines\/gabapentin\/side-effects-of-gabapentin\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">stimulating appetite<\/span><\/a><span style=\"font-weight: 400;\">. Feeling hungrier often results in increased food intake and, consequently, weight gain.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Fluid retention:<\/b> <span style=\"font-weight: 400;\">Another factor to consider is that gabapentin may lead to <\/span><a href=\"https:\/\/www.jwatch.org\/na54218\/2021\/10\/21\/edema-side-effect-gabapentinoid-drugs\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">fluid retention<\/span><\/a><span style=\"font-weight: 400;\"> within the body. Excess fluid can result in temporary weight gain that may be misinterpreted as increased body weight.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Fat storage:<\/b><span style=\"font-weight: 400;\"> The medication can alter the body\u2019s metabolic processes, leading to a greater propensity for fat storage rather than fat burning. This shift can contribute to an overall <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK537590\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">increase in body weight<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Metabolism<\/b><span style=\"font-weight: 400;\">: Gabapentin may affect how efficiently the body metabolizes food. A slowed metabolic rate can make it more challenging for individuals to burn calories effectively, leading to potential weight gain over time.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Energy levels: <\/b><span style=\"font-weight: 400;\">Side effects such as <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK493228\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">dizziness or fatigue<\/span><\/a><span style=\"font-weight: 400;\">, which some individuals experience while taking gabapentin, can make regular physical activity more difficult. Reduced motivation or ability to exercise can further exacerbate weight gain.<\/span><\/li>\n<\/ol>\n<p><span style=\"font-weight: 400;\">If you\u2019re gaining weight while taking gabapentin, the medication could be the culprit, but it\u2019s not the most likely scenario, emphasizes <\/span><a href=\"https:\/\/www.ncoa.org\/adviser\/authors\/raj-dasgupta-md\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Raj Dasgupta, MD<\/span><\/a><span style=\"font-weight: 400;\">, internist and medical adviser for the <\/span><a href=\"https:\/\/www.ncoa.org\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">National Council on Aging (NCOA)<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cWeight gain is an uncommon side effect of gabapentin, and patients should evaluate other reasons for unwanted weight gain,\u201d Dr. Dasgupta says. <\/span><a href=\"https:\/\/www.nichd.nih.gov\/health\/topics\/obesity\/conditioninfo\/cause\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Lifestyle factors<\/span><\/a><span style=\"font-weight: 400;\"> like an unhealthy diet, too much stress, not enough exercise, and insufficient sleep can make weight maintenance and weight loss more difficult.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/gabapentin-side-effects-in-elderly-patients\/\"><b>Gabapentin side effects in elderly patients<\/b><\/a><\/p>\n<h2 id=\"does-gabapentin-make-it-hard-to-lose-weight\"><span style=\"font-weight: 400;\">Does gabapentin make it hard to lose weight?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">It can. Dr. Sylejmani says gabapentin can complicate weight loss efforts due to its effects on appetite regulation, metabolic activity, and energy levels. This combination of factors creates a challenging environment for those trying to maintain or reduce their weight.<\/span><\/p>\n<h2 id=\"tips-for-managing-your-weight-on-gabapentin\"><span style=\"font-weight: 400;\">Tips for managing your weight on gabapentin<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">To help manage weight and mitigate the risk of packing on the pounds while on anticonvulsant medications, Dr. Dasgupta recommends the following strategies:<\/span><\/p>\n<ol>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Exercise portion control:<\/b><span style=\"font-weight: 400;\"> Practicing mindful eating and being aware of portion sizes can help <\/span><a href=\"https:\/\/www.mayoclinic.org\/healthy-lifestyle\/weight-loss\/in-depth\/portion-control\/art-20546800\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">regulate caloric intake<\/span><\/a><span style=\"font-weight: 400;\"> and prevent overeating.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Avoid or minimize processed foods and refined carbohydrates:<\/b><span style=\"font-weight: 400;\"> Reducing the intake of <\/span><a href=\"https:\/\/newsinhealth.nih.gov\/2019\/07\/highly-processed-foods-linked-weight-gain\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">processed foods<\/span><\/a><span style=\"font-weight: 400;\"> like cookies, cakes, crackers, and white bread, which are linked to weight gain, while opting for healthier items like whole grains, lean protein, nuts, beans, fruits, and vegetables, can help stabilize blood sugar levels, thereby decreasing cravings for unhealthy snacks.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Increase your protein intake:<\/b><span style=\"font-weight: 400;\"> Consuming more protein can <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18469287\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">enhance feelings of fullness<\/span><\/a><span style=\"font-weight: 400;\">, which may help curb hunger and lower overall calorie consumption.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Get regular exercise:<\/b> <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5556592\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Consistent physical activity<\/span><\/a><span style=\"font-weight: 400;\"> can counterbalance the potential for weight gain and improve overall health and well-being. Consult your healthcare provider before beginning a new exercise program.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Prioritize your sleep:<\/b><span style=\"font-weight: 400;\"> Ensuring <\/span><a href=\"https:\/\/www.health.harvard.edu\/blog\/snooze-more-eat-less-sleep-deprivation-may-hamper-weight-control-202204042718\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">adequate sleep<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/www.nhlbi.nih.gov\/health\/sleep\/how-much-sleep\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">seven to nine hours<\/span><\/a><span style=\"font-weight: 400;\"> each night for adults) is crucial for effective weight management, as insufficient rest can disrupt hormones responsible for regulating appetite.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Consider an alternative medication:<\/b><span style=\"font-weight: 400;\"> Ask your healthcare provider about switching to a different medication that may have a reduced risk of weight gain.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Consult your provider about a dose adjustment:<\/b><span style=\"font-weight: 400;\"> If feasible, a lower dosage of gabapentin might alleviate some of the side effects, including heightened appetite or weight gain.<\/span><\/li>\n<\/ol>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/what-to-avoid-with-gabapentin\/\"><b>What to avoid when taking gabapentin<\/b><\/a><\/p>\n<h2 id=\"alternatives-to-gabapentin\"><span style=\"font-weight: 400;\">Alternatives to gabapentin<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">While there is no proven algorithm for selecting an anticonvulsant for patients, Dr. Dasgupta says that several <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/gabapentin-alternatives\/\"><span style=\"font-weight: 400;\">alternatives to gabapentin<\/span><\/a><span style=\"font-weight: 400;\"> may be worth exploring for individuals who experience side effects. For example, medications such as lamotrigine, <a href=\"https:\/\/www.singlecare.com\/prescription\/levetiracetam\/dosage\">levetiracetam<\/a>, and topiramate are known to have a lesser association with weight gain (and potentially fewer side effects). On the other hand, Dr. Sylejmani points out that some anticonvulsant medications, including valproate and carbamazepine, are typically linked to weight gain.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The bottom line? If gabapentin is causing weight gain, it is crucial to have a thorough discussion with a healthcare professional, such as a neurologist, to identify the most suitable and tolerated medication for your specific needs, urges Dr. Dasgupta.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Gabapentin (brand name Neurontin) is an anti-seizure medication that is primarily used to alleviate nerve pain and manage seizures. The prescription drug is FDA approved to control seizures in adults and children with epilepsy and treat a type of nerve pain called postherpetic neuralgia (PHN) that can occur after a shingles infection. It\u2019s also used [&hellip;]<\/p>\n","protected":false},"author":135,"featured_media":629399,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[12752,8905,9825],"coauthors":[20608],"class_list":["post-629392","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-medication-side-effects","tag-seasonal","tag-weight-loss","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Does gabapentin cause weight gain? 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