{"id":629652,"date":"2024-09-05T12:15:06","date_gmt":"2024-09-05T16:15:06","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=629652"},"modified":"2025-10-23T19:37:49","modified_gmt":"2025-10-23T23:37:49","slug":"jardiance-vs-glipizide","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/jardiance-vs-glipizide\/","title":{"rendered":"Jardiance vs. glipizide: Differences, similarities & side effects"},"content":{"rendered":"

Jardiance<\/span><\/a> (empagliflozin) and glipizide are prescription medications that are approved by the Food and Drug Administration (FDA) for <\/span>Type 2 diabetes<\/span><\/a>. <\/span>Although both medicines are used for Type 2 diabetes, they belong to different drug classes and have different active ingredients and various other differences. Continue reading to learn more about Jardiance and glipizide.<\/span><\/p>\n

Jardiance vs. glipizide: Key differences<\/span><\/h2>\n

Jardiance is a brand-name drug that contains the active ingredient <\/span>empagliflozin. It is part of a group of drugs called <\/span>sodium-glucose cotransporter 2 (SGLT2) inhibitors<\/span><\/a>. Examples of other drugs in the SGLT2 inhibitor class include <\/span>Farxiga<\/span><\/a> (dapagliflozin) and <\/span>Invokana<\/span><\/a> (canagliflozin). Jardiance <\/span>works by helping the kidneys eliminate sugar in the urine.\u00a0<\/span><\/p>\n

Glipizide<\/span><\/a> is a generic medication that is part of a group of drugs called <\/span>sulfonylureas<\/span><\/a>. It works by helping the pancreas make more insulin (which helps lower blood sugar) and helping the body use insulin more efficiently. Glipizide is available in brand-name form as Glucotrol and Glucotrol XL (an extended-release formulation of glipizide). Other sulfonylurea drugs include <\/span>glyburide<\/span><\/a> and <\/span>glimepiride<\/span><\/a>.<\/span><\/p>\n

Both medications are also available as combination drugs, as one ingredient in a medication that contains more than one ingredient. However, this article will focus on the single-ingredient products Jardiance and glipizide.<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n
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Compare Jardiance vs. glipizide: Key differences<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n

<\/td>\nJardiance<\/b><\/td>\nGlipizide<\/b><\/td>\n<\/tr>\n
Drug class<\/b><\/td>\nSGLT2 inhibitor<\/span><\/td>\nSulfonylurea\u00a0<\/span><\/td>\n<\/tr>\n
Brand\/generic status<\/b><\/td>\nBrand<\/span><\/td>\nGeneric<\/span><\/td>\n<\/tr>\n
What is the generic name?<\/b><\/p>\n

Or<\/b><\/p>\n

What is the brand name?<\/b><\/td>\n

The active ingredient is called empagliflozin, but a generic is not available at this time<\/span><\/td>\nGlucotrol, Glucotrol XL<\/span><\/td>\n<\/tr>\n
What form(s) does the drug come in?<\/b><\/td>\nOral tablet: 10 mg, 25 mg<\/span><\/td>\nOral tablet: 2.5 mg, 5 mg, 10 mg<\/span><\/p>\n

Oral extended-release tablet: 2.5 mg, 5 mg, 10 mg<\/span><\/td>\n<\/tr>\n

What is the standard dosage?<\/b><\/td>\n10 mg or 25 mg by mouth once daily in the morning<\/span><\/a><\/td>\nThe starting dose<\/span><\/a> is usually 5 mg by mouth once daily, and the healthcare provider may gradually increase the dose if needed<\/span><\/td>\n<\/tr>\n
How long is the typical treatment?<\/b><\/td>\nLong-term\u00a0<\/span><\/td>\nLong-term\u00a0<\/span><\/td>\n<\/tr>\n
Who typically uses the medication?<\/b><\/td>\nAdults and pediatric patients 10 years and older for Type 2 diabetes; adults only for all other uses<\/span><\/td>\nAdults\u00a0<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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Jardiance vs. glipizide: Conditions treated<\/span><\/h2>\n

Jardiance is FDA approved for the following uses:<\/span><\/p>\n