{"id":629659,"date":"2024-09-05T15:07:06","date_gmt":"2024-09-05T19:07:06","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=629659"},"modified":"2024-10-25T09:46:02","modified_gmt":"2024-10-25T13:46:02","slug":"synjardy-vs-jardiance","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/synjardy-vs-jardiance\/","title":{"rendered":"Synjardy vs. Jardiance: Differences, similarities & side effects"},"content":{"rendered":"

Synjardy<\/span><\/a> (empagliflozin\/metformin) and <\/span>Jardiance<\/span><\/a> (empagliflozin) are prescription medications approved by the Food and Drug Administration (FDA) for <\/span>Type 2 diabetes<\/span><\/a>.<\/span> Although both medicines are used for Type 2 diabetes, they are not exactly the same. Continue reading to learn more about Synjardy and Jardiance.<\/span><\/p>\n

Synjardy vs. Jardiance: Key differences<\/span><\/h2>\n

Synjardy contains two ingredients that work together. The first ingredient is empagliflozin, which is classified as a <\/span>sodium-glucose cotransporter 2 (SGLT2) inhibitor<\/span><\/a>. The second ingredient is <\/span>metformin<\/span><\/a> (also known as metformin hydrochloride), which is classified as a <\/span>biguanide<\/span><\/a> drug. Empagliflozin works by helping the kidneys eliminate sugar, or glucose, in the urine. Metformin works by decreasing the amount of sugar made in the liver, helping the intestines absorb glucose, and improving insulin sensitivity. <\/span><\/p>\n

Jardiance contains one ingredient—<\/span>empagliflozin<\/span><\/a>, one of the two ingredients <\/span>in Synjardy. It works by helping the kidneys eliminate sugar in the urine. <\/span><\/p>\n

Both Synjardy and Jardiance are made by the pharmaceutical company <\/span>Boehringer Ingelheim Pharmaceuticals, Inc.<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n
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Compare Synjardy vs. Jardiance key differences<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n

<\/td>\nSynjardy<\/b><\/td>\nJardiance<\/b><\/td>\n<\/tr>\n
Drug class<\/b><\/td>\nSGLT2 inhibitor\/biguanide<\/span><\/td>\nSGLT2 inhibitor<\/span><\/td>\n<\/tr>\n
Brand\/generic status<\/b><\/td>\nBrand<\/span><\/td>\nBrand<\/span><\/td>\n<\/tr>\n
What is the generic name?<\/b><\/td>\nThe active ingredients are empagliflozin and metformin, but a generic is not available at this time<\/span><\/td>\nThe active ingredient is called empagliflozin, but a generic is not available at this time<\/span><\/td>\n<\/tr>\n
What form(s) does the drug come in?<\/b><\/td>\nOral tablet: <\/span>5 mg empagliflozin\/500 mg metformin, 5 mg\/1,000 mg, 12.5 mg\/500 mg, 12.5 mg\/1,000 mg<\/span><\/p>\n

Oral extended-release tablet: 5 mg\/1,000 mg, 10 mg\/1,000 mg, 12.5 mg\/1,000 mg, 25 mg\/1000 mg<\/span><\/td>\n

Oral tablet: 10 mg, 25 mg<\/span><\/td>\n<\/tr>\n
What is the standard dosage?<\/b><\/td>\nVaries depending on previous treatment<\/span><\/td>\n10 mg or 25 mg by mouth once daily in the morning<\/span><\/a><\/td>\n<\/tr>\n
How long is the typical treatment?<\/b><\/td>\nLong-term<\/span><\/td>\nLong-term <\/span><\/td>\n<\/tr>\n
Who typically uses the medication?<\/b><\/td>\nSynjardy: Adults and pediatric patients 10 years and older<\/span><\/p>\n

Synjardy XR: Adults only<\/span><\/td>\n

Adults and pediatric patients 10 years and older for Type 2 diabetes; adults only for all other uses<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Synjardy vs. Jardiance: Conditions treated<\/span><\/h2>\n

Synjardy is FDA approved to improve blood sugar control, or glycemic control, in adults and pediatric patients 10 years and older with <\/span>Type 2 diabetes<\/span><\/a>, usually in combination with diet and exercise. <\/span>Synjardy XR<\/span><\/a> is an extended-release formulation of Synjardy that is also used for Type 2 diabetes but is approved for adults only. Synjardy XR is not approved for use in pediatric patients.<\/span><\/p>\n

Although Synjardy contains empagliflozin, a component of Jardiance, it also contains metformin, which is only used for diabetes. Therefore, Synjardy should only be used in people with Type 2 diabetes. It <\/span>can be used<\/span><\/a> in adults with both Type 2 diabetes and cardiovascular disease to lower the risk of heart-related death. It can also be used to lower the risk of cardiovascular death and heart failure hospitalization in adults with Type 2 diabetes and heart failure.  <\/span><\/p>\n

Jardiance<\/span><\/a> is FDA approved for the following conditions:<\/span><\/p>\n