{"id":629694,"date":"2024-09-10T09:14:24","date_gmt":"2024-09-10T13:14:24","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=629694"},"modified":"2024-10-25T09:45:47","modified_gmt":"2024-10-25T13:45:47","slug":"give-dog-metronidazole-without-food","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/give-dog-metronidazole-without-food\/","title":{"rendered":"Can I give my dog metronidazole without food?"},"content":{"rendered":"<p><a href=\"https:\/\/www.singlecare.com\/prescription\/metronidazole\"><span style=\"font-weight: 400;\">Metronidazole<\/span><\/a><span style=\"font-weight: 400;\"> is a prescription medication that&rsquo;s sold under the brand name <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/flagyl\"><span style=\"font-weight: 400;\">Flagyl<\/span><\/a><span style=\"font-weight: 400;\">. It&rsquo;s in a class of medications called<\/span> <a href=\"https:\/\/medlineplus.gov\/druginfo\/meds\/a689011.html\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">nitroimidazole antimicrobials<\/span><\/a><span style=\"font-weight: 400;\">. Metronidazole is<\/span> <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK539728\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">FDA approved<\/span><\/a><span style=\"font-weight: 400;\"> to treat a broad range of infections in humans, including skin infections, bacterial infections, protozoal infections, GI tract infections, and vaginal infections. It&rsquo;s <\/span><a href=\"https:\/\/www.merckvetmanual.com\/pharmacology\/antibacterial-agents\/nitroimidazoles-use-in-animals\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">used off-label <\/span><\/a><span style=\"font-weight: 400;\">to treat various infections in dogs.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Metronidazole is &ldquo;both an antibiotic and antiprotozoal medication that is prescribed for dogs with infections, including those caused by bacteria and protozoans such as Giardia,&rdquo; says Amy Attas, VMD, veterinarian and author of <\/span><a href=\"https:\/\/www.dramyattas.com\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Pets and the City: True Tales of a Manhattan House Call Veterinarian<\/span><\/a><span style=\"font-weight: 400;\">. In particular, the medication is a<\/span> <a href=\"https:\/\/www.akc.org\/expert-advice\/health\/metronidazole-for-dogs\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">first-line treatment<\/span><\/a><span style=\"font-weight: 400;\"> for dog diarrhea.<\/span><\/p>\n<p>Here, we&rsquo;ll consider the potential side effects of giving dogs metronidazole without food and how best to administer the medication so that your dog will feel better as soon as possible.<\/p>\n<h2 id=\"can-you-give-metronidazole-to-your-dog-without-food\"><span style=\"font-weight: 400;\">Can you give metronidazole to your dog without food?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Vets agree that it&rsquo;s best to give metronidazole to a dog with food, rather than on an empty stomach. &ldquo;It is generally recommended to give this medication with food to reduce potential gastrointestinal upset from it,&rdquo; Dr. Attas says.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Bethany Hsia, DVM, veterinarian, and co-founder of <\/span><a href=\"http:\/\/www.codapet.com\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">CodaPet<\/span><\/a><span style=\"font-weight: 400;\">, is on the same page. &ldquo;Most veterinarians recommend giving metronidazole with food to minimize your dog having a stomach ache or gastrointestinal upset,&rdquo; Dr. Hsia describes. &ldquo;Metronidazole can be harsh on your dog&rsquo;s stomach so administering it with food can help reduce stomach irritation and also improve metronidazole&rsquo;s effectiveness.&rdquo;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">While metronidazole could theoretically be given to dogs on an empty stomach, Nita Vasudevan, DVM, veterinary consultant for<\/span> <a href=\"https:\/\/www.embracepetinsurance.com\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Embrace Pet Insurance<\/span><\/a><span style=\"font-weight: 400;\">, doesn&rsquo;t recommend this. She says that the potential for an upset stomach is possible for any dog, but certain dogs have an increased risk; &ldquo;Dogs with a history of digestive sensitivity or past stomach issues may be more prone to experiencing nausea, vomiting, or loss of appetite when metronidazole is administered on an empty stomach.&rdquo;&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The bottom line? It&rsquo;s better to be safe than sorry, so give your dog their metronidazole with food.<\/span><\/p>\n<h2 id=\"benefits-of-giving-metronidazole-with-food\"><span style=\"font-weight: 400;\">Benefits of giving metronidazole with food<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">It&rsquo;s best to give metronidazole to dogs with food. The main benefit is that it reduces the risk of gastrointestinal side effects, including<\/span> <a href=\"https:\/\/vcahospitals.com\/know-your-pet\/metronidazole\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">nausea and vomiting<\/span><\/a><span style=\"font-weight: 400;\">. But there are other benefits to consider, too.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">First of all, metronidazole is &ldquo;notoriously a very bitter medication,&rdquo; says Dr. Vasudevan. Taking it with food &ldquo;acts as a buffer, reducing direct contact between the stomach lining and the medication, which can be irritating,&rdquo; she describes.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Other benefits include that your dog will be more likely to swallow the pill with food, and it reduces the likelihood that they will spit it out. &ldquo;This method is often preferred to ensure the dog&rsquo;s comfort and compliance,&rdquo; Dr. Vasudevan says. She warns against crushing pills and adding them to food because this will make the medication less palatable, and the dog may not take the full dose of the drug.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Finally, in some cases, having your dog take metronidazole with food will ensure effectiveness. &ldquo;The food combined with the medicine will help enhance absorption so your dog receives the full medical effect of the medicine while minimizing stomach discomfort,&rdquo; says Dr. Hsia.<\/span><\/p>\n<h2 id=\"risks-of-giving-metronidazole-to-your-dog-on-an-empty-stomach\"><span style=\"font-weight: 400;\">Risks of giving metronidazole to your dog on an empty stomach<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">While metronidazole is generally well tolerated in dogs, serious side effects are possible. These side effects are more likely to happen if you give metronidazole in high doses. Too much metronidazole can cause metronidazole toxicity.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">&#8203;Possible<\/span> <a href=\"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/260\/S3\/javma.22.08.0349.xml\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">side effects of metronidazole<\/span><\/a><span style=\"font-weight: 400;\"> in dogs include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Decreased appetite<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Vomiting<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Seizures<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Neurological symptoms<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Neutropenia (when you have lower than normal levels of a type of white blood cell called neutrophils)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Disturbances to the GI tract microbiome<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">The main risk of giving your dog metronidazole without food is that you would increase the chances of an upset stomach. This can manifest as nausea, vomiting, or diarrhea, says Dr. Vasudevan. The chances of this happening are greater for certain dogs. &ldquo;In dogs with pre-existing conditions such as gastritis or other forms of stomach sensitivity, these side effects may worsen,&rdquo; Dr. Vasudevan explains.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In rare cases, other serious side effects can happen if you administer metronidazole to your dog on an empty stomach. Doing so could lead to an overall refusal to eat, says Dr. Vasudevan, which would mean your dog doesn&rsquo;t receive adequate treatment for their condition.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Besides making sure to take metronidazole with food, you should also review any other medications your dog is taking with their vet before giving them metronidazole. &ldquo;While metronidazole is generally safe, potential drug interactions should be considered, particularly if the dog is on other medications that can irritate the stomach or alter gut flora,&rdquo; Dr. Vasudevan advises.<\/span><\/p>\n<h2 id=\"summary\"><span style=\"font-weight: 400;\">Summary<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">It is safe and effective to give metronidazole to a dog, and it can be helpful in treating dog diarrhea, bacterial infections, and protozoal infections. Vets recommend that you give your dog metronidazole with food. This will decrease GI tract side effects like nausea and vomiting. It also makes the medication more palatable so that your dog won&rsquo;t reject it.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If you have further questions or concerns about administering metronidazole to your dog, please contact your veterinarian. Your vet can also discuss potential side effects and the best dosage for your dog.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Metronidazole is a prescription medication that&rsquo;s sold under the brand name Flagyl. It&rsquo;s in a class of medications called nitroimidazole antimicrobials. Metronidazole is FDA approved to treat a broad range of infections in humans, including skin infections, bacterial infections, protozoal infections, GI tract infections, and vaginal infections. It&rsquo;s used off-label to treat various infections in [&hellip;]<\/p>\n","protected":false},"author":133,"featured_media":629698,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[7956],"tags":[7969],"coauthors":[20899],"class_list":["post-629694","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pets","tag-dogs","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Can I give my dog metronidazole without food?<\/title>\n<meta name=\"description\" content=\"Vets recommend giving your dog metronidazole with food to minimize nausea and vomiting. 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