{"id":629699,"date":"2024-09-10T09:58:56","date_gmt":"2024-09-10T13:58:56","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=629699"},"modified":"2026-03-23T15:35:49","modified_gmt":"2026-03-23T19:35:49","slug":"restasis-alternatives","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/restasis-alternatives\/","title":{"rendered":"Restasis alternatives: What can I take instead of Restasis?"},"content":{"rendered":"

Restasis (cyclosporine .05% ophthalmic emulsion) is the brand name of a prescription medication approved by the U.S. Food and Drug Administration (FDA) to manage dry eye disease. The terms “dry eye disease (DED),” “dry eye syndrome (DES),” “keratoconjunctivitis sicca (KCS),” and “chronic dry eye” all refer to the same condition. Restasis is a calcineurin inhibitor immunosuppressant that can increase tear production, but its onset of action takes up to 12 weeks. Restasis may cause side effects like <\/span>eye pain<\/span><\/a> and a temporary burning sensation right after administration.\u00a0<\/span><\/p>\n

RELATED: <\/b>Restasis dosage, forms, and strengths<\/b><\/a><\/p>\n

What can I take in place of Restasis?<\/span>
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Dry eye disease is a common eye disorder, with a prevalence as high as <\/span>50%<\/span><\/a> in certain regions. In the United States, one study estimated that <\/span>8.1%<\/span><\/a> of the adult population has been diagnosed with dry eye disease. Factors like low humidity, wind, allergens, smoke, and eye strain may contribute to dry eye disease. It can also be a side effect of medications or result from different health conditions.\u00a0<\/span><\/p>\n

Over-the-counter (OTC) products<\/span><\/a> to treat the symptoms of dry eye disease include topical gels, liquids, and ointments. It is best to avoid products marketed to relieve red eyes since they generally contain medications that can exacerbate symptoms. However, many individuals suffering from dry eye disease do not experience complete relief from OTC eye drops alone.\u00a0<\/span><\/p>\n

Prescription medications for dry eye disease include different formulations of the active ingredient of Restasis, and other topicals with different active ingredients. An ophthalmologist can provide medical advice to find alternatives to Restasis. <\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n
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\u00a0 \u00a0 \u00a0 \u00a0 \u00a0Compare Restasis alternatives<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n

Drug name<\/b><\/td>\nPrice without insurance<\/b><\/td>\nSingleCare price<\/b><\/td>\nSavings options<\/b><\/td>\n<\/tr>\n
Restasis (cyclosporine 0.05% ophthalmic emulsion)\u00a0<\/span><\/td>\n$410 for 30 single-use doses\u00a0<\/span><\/td>\n$54 for 30 single-use doses at CVS<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Cequa <\/span>(cyclosporine 0.09% ophthalmic solution)<\/span><\/td>\n$889 for 60 single-use solution doses\u00a0\u00a0<\/span><\/td>\n$639 for 60 single-use solution doses at Kroger or Harris Teeter<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Vevye (cyclosporine 0.1% ophthalmic solution)<\/span><\/td>\n$1097 per 1, 2 mL bottle\u00a0\u00a0<\/span><\/td>\n$755 per 1, 2 mL bottle at Kroger or Harris Teeter<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Xiidra (lifitegrast 5% ophthalmic solution)<\/span><\/td>\n$1018 for 60 single-use solution doses\u00a0<\/span><\/td>\n$726 for 60 single-use doses\u00a0 at Kroger or Harris Teeter<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Tyrvaya (varenicline 0.03 mg\/spray nasal solution)\u00a0<\/span><\/td>\n$940 for 2, 4.2 mL bottles\u00a0\u00a0<\/span><\/td>\n$685 for 2, 4.2 mL bottles at Kroger or Harris Teeter<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Miebo (perfluorohexyloctane ophthalmic solution)\u00a0<\/span><\/td>\n$1,243 for 1, 3 mL bottle\u00a0\u00a0<\/span><\/td>\n$810 for 1, 3 mL bottle at Kroger or Harris Teeter<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Prescription drug prices often change. These are the most accurate medication prices at the time of publishing in ZIP code 23666 as of March 23, 2026. The listed price without insurance references the price of brand-name drugs (unless otherwise specified). The listed SingleCare price references the price of generic drugs if available.<\/span><\/i><\/small><\/small><\/p>\n\t\t

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Save up to 80% on Restasis with SingleCare<\/p>\n\t\t\t

Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t

\n\t\t\t\t
\n\t\t\t\t\tRestasis .05% (60 Emulsion)\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t
\n\t\t\t\"CVS\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t$57.96\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\ti<\/span>\n\t\t\t\t\tPrice with signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\tGet free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\"Publix\"\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t$98.63\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\ti<\/span>\n\t\t\t\t\tPrice with signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\tGet free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\tSee Restasis prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n

Over-the-counter alternatives to treat dry eyes<\/span><\/h2>\n

There are many OTC treatments available to treat the symptoms of dry eye. They may provide temporary relief, but they don\u2019t work for everyone. Some OTC treatments include:<\/span><\/p>\n