{"id":629759,"date":"2024-09-11T15:41:28","date_gmt":"2024-09-11T19:41:28","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=629759"},"modified":"2025-09-12T16:31:47","modified_gmt":"2025-09-12T20:31:47","slug":"phentermine-and-adderall","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/phentermine-and-adderall\/","title":{"rendered":"Can you take phentermine and Adderall?"},"content":{"rendered":"

Adderall and phentermine are both central nervous system stimulants. Adderall (dextroamphetamine and amphetamine) is used for attention deficit hyperactivity disorder (ADHD) and narcolepsy. At the same time, phentermine is approved by the U.S. Food and Drug Administration (FDA) for short-term use in weight management for patients with obesity or who are overweight. These medical conditions can overlap, determining whether Adderall and phentermine can be taken together. In short, they can be used concurrently, but there is a large asterisk on that statement referring to cardiovascular concerns with using two central nervous system (<\/span>CNS<\/span><\/a>) stimulants.<\/span><\/p>\n

Can you take phentermine with Adderall?<\/span><\/h2>\n

Although <\/span>phentermine<\/span><\/a>, known as Adipex-P, can be taken with the brand name <\/span>Adderall<\/span><\/a>, using this drug duo deserves added attention to cardiovascular monitoring, according to the <\/span>MedScape interaction checker<\/span><\/a>. Blood pressure and heart rate should be watched because two of the serious side effects of stimulant medications are tachycardia (fast heart rate) and hypertension (elevated blood pressure).<\/span><\/p>\n

Naturally, the level of concern with this drug combination is heightened for certain individuals. Patients with heart disease or uncontrolled hypertension are typically advised to avoid stimulants in general, including phentermine and Adderall. Tachycardia can provoke heart failure, heart attack, or rhythm disturbances, particularly in patients who are prone to underlying cardiovascular disease.<\/span><\/p>\n

The low cost and benefits of improved focus with <\/span>Adderall<\/span><\/a> and reduced appetite from <\/span>phentermine<\/span><\/a> must be balanced against the risk of side effects. Using two stimulants together could increase the risks for some people and affect the balance of benefits and risks. It’s important to make decisions about whether to use one or two stimulants on an individual basis, with medical advice from a healthcare provider.<\/span><\/p>\n

One of the factors to consider is what other prescription medications, over-the-counter meds, and supplements are taken. For example, the common <\/span>antidepressants<\/span><\/a> Zoloft (sertraline), Celexa (citalopram), and Lexapro (escitalopram) can interact with phentermine and Adderall, leading to a higher likelihood of <\/span>serotonin syndrome<\/span><\/a>, a dangerous state of overstimulation of the CNS.\u00a0<\/span><\/p>\n

Adderall and phentermine promote the release of brain neurotransmitters like dopamine and norepinephrine. Antidepressants can do so too. Taking multiple medicines with this potential leads to additive risk, meaning that coupling phentermine with Adderall in someone already taking an antidepressant could be a bad idea.<\/span><\/p>\n

What happens if you take phentermine and Adderall together?<\/span><\/h2>\n

Yes, taking both prescription drugs<\/a> could ensure that ADHD symptoms remain controlled with Adderall while obesity is addressed with phentermine. Adderall\u2019s common side effect of appetite suppression is the desired effect of phentermine. Other side effects of both medications include dry mouth and constipation. However, the more serious side effects of <\/span>phentermine<\/span><\/a> and <\/span>Adderall<\/span><\/a> must be considered, including the following:<\/span><\/p>\n