{"id":629895,"date":"2024-09-24T17:44:03","date_gmt":"2024-09-24T21:44:03","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=629895"},"modified":"2025-02-19T15:49:56","modified_gmt":"2025-02-19T20:49:56","slug":"does-wegovy-affect-menstrual-cycle","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/does-wegovy-affect-menstrual-cycle\/","title":{"rendered":"Does Wegovy affect your menstrual cycle?"},"content":{"rendered":"

As one of only three glucagon-like peptide 1 (GLP-1) receptor agonists approved for weight loss in people with obesity or who are overweight, <\/span>Wegovy<\/span><\/a> (semaglutide) is on its way to becoming as popular as its <\/span>Type 2 diabetes-approved counterpart, Ozempic<\/span><\/a>.\u00a0<\/span><\/p>\n

In addition to weight loss, the Food and Drug Administration (FDA) has approved Wegovy for <\/span>reducing the risk of heart problems<\/span><\/a> in adults with cardiovascular disease who either have obesity or are overweight. But with more people using Wegovy, there\u2019s been an uptick in the reporting of symptoms not originally seen in clinical trials. For example, since <\/span>Wegovy was FDA approved for weight loss<\/span><\/a> in 2021, women taking the drug have reported changes to their menstrual cycle, including vaginal spotting and irregular or more frequent menstrual periods.\u00a0<\/span><\/p>\n

Wegovy is known to stabilize your blood sugar, slow down your digestion, and suppress your appetite, but it isn\u2019t known to directly impact your menstrual cycle\u2014so why are women reporting changes? Here\u2019s what you need to know about Wegovy and its potential connection to your period, including what you should do if you experience menstrual changes while taking it.<\/span><\/p>\n

Wegovy and menstrual cycle changes<\/span><\/h2>\n

According to <\/span>Katrina Mattingly, MD<\/span><\/a>, obesity medicine specialist and chief medical officer of physician-supervised weight loss center Options Medical Weight Loss, women have been reporting various menstrual cycle changes on Wegovy\u2014from lighter, shorter periods to heavier periods.<\/span><\/p>\n

However, the most common change reported so far seems to be the normalization of menstrual cycles. Though reports are preliminary at this point and more research is needed, a few small studies and a flood of anecdotal evidence suggest that overweight women who were not menstruating regularly before taking Wegovy are now having more regular periods.\u00a0<\/span><\/p>\n

In some cases, these changes have resulted not only in a normal menstrual cycle but also in pregnancy for women who previously struggled with infertility or had a history of <\/span>polycystic ovarian syndrome (PCOS)<\/span><\/a>. \u201c[People who] experienced irregular cycles or fertility are reporting more regular and predictable cycles with an uptick in pregnancies,\u201d Dr. Mattingly says. This is sometimes referred to as the \u201c<\/span>Ozempic baby boom<\/span><\/a>,\u201d as Ozempic and Wegovy share the same active ingredient: semaglutide.<\/span><\/p>\n

Can Wegovy affect your period?<\/span><\/h2>\n

To be clear, Wegovy itself hasn\u2019t been shown to have any direct impact on your reproductive system or your menstrual cycle, but that doesn\u2019t mean there\u2019s no connection between Wegovy and period changes at all.\u00a0<\/span><\/p>\n

\u201cWegovy can potentially impact the menstrual cycle by causing rapid weight loss,\u201d says <\/span>Kecia Gaither, MD<\/span><\/a>, an OB-GYN and maternal-fetal medicine specialist and director of Perinatal Services\/Maternal Fetal Medicine at NYC Health + Hospitals\/Lincoln in the Bronx. \u201cSignificant weight loss can impact [the hormonal balance of estrogen and progesterone], leading to menstrual irregularities like missed periods, heavy or light periods, and irregular periods.\u201d<\/span><\/p>\n

\u201cThis is especially true when your estrogen levels change due to weight loss,\u201d says Dr. Mattingly. Estrogen is a key regulator in your menstrual cycle that\u2019s produced by fatty (adipose) tissue. And when you lose large amounts of fat, your estrogen levels can also drop, potentially causing lighter or shorter cycles and disrupting a previously normal, predictable cycle.<\/span><\/p>\n

However, the opposite can also be true, especially for women who did <\/span>not <\/span><\/i>have regular menstrual cycles before taking Wegovy. \u201cWeight loss also helps increase insulin sensitivity and decrease insulin resistance, which is helpful [in normalizing menstrual cycles] for patients with PCOS,\u201d Dr. Mattingly says.<\/span><\/p>\n

For example, <\/span>a recent, small study of women with PCOS and obesity<\/span><\/a> found that six months of low-dose semaglutide normalized menstrual cycles and significantly lowered body mass index (BMI) in 80% of participants. Previously, the participants had not responded to other types of weight loss treatments or lifestyle changes. Although Wegovy isn\u2019t FDA approved for the treatment of PCOS, it\u2019s often <\/span>prescribed as an off-label treatment<\/span><\/a> in combination with other medications and lifestyle changes.<\/span><\/p>\n

Since Wegovy is still a relatively new weight loss medication, experts are working with preliminary information about its effects on the menstrual cycle. More research is needed before a clear relationship can be defined or predictions can be made about how likely it is that Wegovy will affect your period, especially since the medication doesn\u2019t directly affect menstruation.\u00a0<\/span><\/p>\n

What to do if you experience menstrual changes on Wegovy<\/span><\/h2>\n

\u201cYou shouldn\u2019t be alarmed or concerned if you notice some minor changes to your period or even your premenstrual symptoms. Both weight loss fluctuations <\/span>and <\/span><\/i>hormones play major roles in the regulation of your cycle,\u201d Dr. Mattingly says.<\/span><\/p>\n

Additionally, common Wegovy side effects like nausea, vomiting, and suppressed appetite can impact the overall intake of protein, nutrients, and fluids, all of which help <\/span>support a healthy menstrual cycle<\/span><\/a>, according to Dr. Mattingly. If you think your lighter or heavier periods are diet-related, she recommends taking a daily vitamin and drinking protein shakes, electrolyte replacements, or bone broth to replenish these key nutrients and fluids.\u00a0<\/span><\/p>\n

RELATED: <\/b>Does Wegovy make you tired?<\/b><\/a><\/p>\n

That said, you should let your healthcare provider know if you\u2019re experiencing changes to your menstrual period while taking Wegovy. Dr. Gaither says it\u2019s important to determine whether the medication is actually causing those changes or if they have another cause. Likewise, if Wegovy is causing serious, disruptive changes to your cycle, Dr. Gaither says you may need to adjust your dosage or even switch medications.\u00a0<\/span><\/p>\n

Finally, Dr. Mattingly says women of childbearing age experiencing menstrual changes like <\/span>missed periods<\/span><\/a> or spotting on Wegovy should confirm they aren\u2019t pregnant\u2014even if they\u2019re on birth control. Because Wegovy delays gastric emptying (the rate at which food moves through your stomach), Dr. Mattingly says oral contraceptives are being absorbed more slowly, too, and may become less effective. Experts don\u2019t know yet about the safety of taking <\/span>semaglutide<\/span><\/a> during pregnancy, so it\u2019s important to confirm pregnancy as soon as possible while taking Wegovy and get in touch with your healthcare provider about discontinuing the medication.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

As one of only three glucagon-like peptide 1 (GLP-1) receptor agonists approved for weight loss in people with obesity or who are overweight, Wegovy (semaglutide) is on its way to becoming as popular as its Type 2 diabetes-approved counterpart, Ozempic.\u00a0 In addition to weight loss, the Food and Drug Administration (FDA) has approved Wegovy for […]<\/p>\n","protected":false},"author":149,"featured_media":629896,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[788,21067,8670],"coauthors":[8860],"class_list":["post-629895","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-drug-safety","tag-glp-1-drugs","tag-womens-health","wpautop"],"acf":[],"yoast_head":"\nDoes Wegovy affect your menstrual cycle?<\/title>\n<meta name=\"description\" content=\"Wegovy doesn\u2019t have a direct impact on your period, but 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