{"id":629897,"date":"2024-10-07T09:30:35","date_gmt":"2024-10-07T13:30:35","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=629897"},"modified":"2024-10-25T09:42:33","modified_gmt":"2024-10-25T13:42:33","slug":"foods-to-avoid-while-taking-januvia","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/foods-to-avoid-while-taking-januvia\/","title":{"rendered":"5 foods to avoid while taking Januvia"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Some people with diabetes need more than dietary changes and regular exercise to manage the condition. Prescription drugs like <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/januvia\"><span style=\"font-weight: 400;\">Januvia (sitagliptin)<\/span><\/a><span style=\"font-weight: 400;\"> can help maintain <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/normal-blood-glucose-levels\/\"><span style=\"font-weight: 400;\">healthy blood sugar levels<\/span><\/a><span style=\"font-weight: 400;\">. Manufactured by Merck, Januvia is a once-daily tablet that lowers blood sugar when it rises too high (hyperglycemia).<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Januvia is FDA approved for people with Type 2 diabetes. However, it may be used <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/off-label-prescription-drugs\/\"><span style=\"font-weight: 400;\">off-label<\/span><\/a><span style=\"font-weight: 400;\"> for conditions like metabolic syndrome and polycystic ovarian syndrome (PCOS), according to <\/span><a href=\"https:\/\/www.medicalofficesofmanhattan.com\/our-team\/daniel-kim-do\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Daniel Kim<\/span><\/a><span style=\"font-weight: 400;\">, DO, a family physician with Medical Offices of Manhattan.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Unlike many medications, there aren&rsquo;t any foods that directly interact with Januvia. However, you should still try to moderate or avoid certain foods because of their impact on your blood sugar, such as sugary foods, refined carbs, and alcohol. Here&rsquo;s what to know about the foods to avoid on Januvia.<\/span><\/p>\n<h2 id=\"how-januvia-works\"><span style=\"font-weight: 400;\">How Januvia works<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Januvia belongs to a class of medications known as <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK542331\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">dipeptidyl peptidase 4 (DPP-4) inhibitors<\/span><\/a><span style=\"font-weight: 400;\">, which means it blocks certain enzymes that make it harder for your body&rsquo;s metabolic hormones to keep your blood sugar levels stable after you eat.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In doing this, Januvia helps to prevent post-meal glucose spikes in the blood, says <\/span><a href=\"https:\/\/aeroflowdiabetes.com\/libu-v-endo\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Libu Varughese<\/span><\/a><span style=\"font-weight: 400;\">, MD, endocrinologist and medical advisor for Aeroflow Diabetes, noting that it works particularly well in the two hours after a meal to make sure your blood sugar doesn&rsquo;t get too high or too low.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In the short-term, Dr. Kim says Januvia can have an impact on your blood sugar levels within a few hours of taking it; in the long-term, he says you may see improvements in high blood sugar levels after a few weeks of starting the medication.<\/span><\/p>\n<h2 id=\"5-foods-to-avoid-with-januvia\"><span style=\"font-weight: 400;\">5 foods to avoid with Januvia<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">According to Dr. Varughese, you don&rsquo;t need to worry about the foods you eat interfering with Januvia or preventing it from working. However, foods that cause dramatic glucose spikes are generally not recommended for people with Type 2 diabetes, and they can make it harder for Januvia to have the same effect on your blood sugar.<\/span><\/p>\n<h3 id=\"1-sugary-foods-and-drinks\"><span style=\"font-weight: 400;\">1. Sugary foods and drinks<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">People taking DPP-4 inhibitors like Januvia should limit or avoid foods and drinks with a high sugar content. Sugary snacks and beverages cause a rapid spike in blood sugar levels, says Dr. Varughese, making Januvia less effective at stabilizing your glucose.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">For the most part, this means moderating your intake of cake and candy, sodas and fruit juices, and other pre-packaged treats, but not necessarily fruits that contain natural sugars, like bananas and <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/are-grapes-good-for-diabetics\/\"><span style=\"font-weight: 400;\">grapes<\/span><\/a><span style=\"font-weight: 400;\">. Though <\/span><a href=\"https:\/\/diabetes.org\/food-nutrition\/reading-food-labels\/fruit\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">fruit should be eaten in moderation if you have Type 2 diabetes<\/span><\/a><span style=\"font-weight: 400;\">, you don&rsquo;t have to avoid it completely (and thanks to other nutrients, like fiber, fruit is a much healthier choice than a bowl of ice cream!).<\/span><\/p>\n<h3 id=\"2-refined-carbohydrates\"><span style=\"font-weight: 400;\">2. Refined carbohydrates<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">There are <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/what-are-carbohydrates\/\"><span style=\"font-weight: 400;\">two types of carbohydrates<\/span><\/a><span style=\"font-weight: 400;\">: simple (refined) and complex. Refined carbs are processed and don&rsquo;t have as many nutrients, plus they&rsquo;re digested quickly and can cause your blood sugar to spike; complex carbs, on the other hand, are whole grains full of fiber and other vitamins, and they cause a slow and steady blood sugar increase that&rsquo;s recommended for people with Type 2 diabetes.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">As much as possible, you should focus on eating complex carbs such as oats, barley, brown rice, and beans instead of refined carbs like white rice, white pasta, snack crackers, pretzels, and sugary cereals, especially when taking Januvia. These <\/span><a href=\"https:\/\/www.cdc.gov\/diabetes\/healthy-eating\/choosing-healthy-carbs.html\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">complex carbs<\/span><\/a><span style=\"font-weight: 400;\"> won&rsquo;t cause a spike in blood sugar and will allow your medication to keep your glucose levels in check more efficiently.<\/span><\/p>\n<h3 id=\"3-starchy-vegetables\"><span style=\"font-weight: 400;\">3. Starchy vegetables<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">While vegetables, in general, are diabetic diet-friendly, it&rsquo;s best to limit the ones that are high in starch because they are also higher in carbohydrates&mdash;and <\/span><a href=\"https:\/\/www.ama-assn.org\/delivering-care\/diabetes\/foods-spike-patient-s-blood-glucose-are-not-what-you-think\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">the more carbohydrates in a food, the more it contributes to a rise in blood sugar<\/span><\/a><span style=\"font-weight: 400;\">. Starchy vegetables include potatoes, corn, winter squash, and peas. That doesn&rsquo;t mean you can&rsquo;t eat them at all; these starchy vegetables have more carbs than their non-starchy counterparts, but they&rsquo;re complex carbs (meaning they&rsquo;re still better for you than the simple carbs found in white bread or rice).<\/span><\/p>\n<p><span style=\"font-weight: 400;\">However, if your <\/span><a href=\"https:\/\/hopkinsdiabetesinfo.org\/the-truth-about-starchy-vegetables\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">diabetes diet plan requires you to count carbs closely<\/span><\/a><span style=\"font-weight: 400;\"> while taking Januvia, you&rsquo;ll be able to eat more non-starchy vegetables like broccoli, eggplant, green beans, carrots, and zucchini, and that will help you feel fuller and more satisfied without the sharp rise in blood glucose levels.<\/span><\/p>\n<h3 id=\"4-alcohol\"><span style=\"font-weight: 400;\">4. Alcohol<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Alcohol contains <\/span><a href=\"https:\/\/www.umassmed.edu\/dcoe\/diabetes-education\/patient-resources\/alcohol-and-diabetes\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">varying amounts of carbohydrates<\/span><\/a><span style=\"font-weight: 400;\"> (depending on what type you&rsquo;re drinking and whether it&rsquo;s been mixed with other ingredients), which can make it hard for people with diabetes to accurately evaluate how alcohol fits into their daily diet.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Though that&rsquo;s important to keep in mind, it&rsquo;s <\/span><i><span style=\"font-weight: 400;\">not <\/span><\/i><span style=\"font-weight: 400;\">the main reason why many experts recommend moderating your alcohol intake while taking diabetes medications like Januvia. It&rsquo;s actually because <\/span><a href=\"https:\/\/diabetes.org\/health-wellness\/alcohol-and-diabetes\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">alcohol lowers your blood sugar<\/span><\/a><span style=\"font-weight: 400;\"> thanks to the way it&rsquo;s processed in your liver. When you combine alcohol with glycemic-lowering medications like Januvia, you&rsquo;re at risk of hypoglycemia or dangerously low levels of blood sugar.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">You may not need to stop drinking alcohol entirely, but you should talk to your healthcare provider about how to safely consume it while taking Januvia. There are ways to <\/span><a href=\"https:\/\/dtc.ucsf.edu\/living-with-diabetes\/diet-and-nutrition\/diabetes-alcohol\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">reduce the risk of hypoglycemia<\/span><\/a><span style=\"font-weight: 400;\">, like never drinking on an empty stomach and knowing the symptoms of low blood sugar.<\/span><\/p>\n<h3 id=\"5-excessive-caffeine\"><span style=\"font-weight: 400;\">5. Excessive caffeine<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">For most people without diabetes, the normal amount of caffeine (i.e., 400 milligrams or less) <\/span><a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/type-2-diabetes\/expert-answers\/blood-sugar\/faq-20057941\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">won&rsquo;t affect your blood sugar<\/span><\/a><span style=\"font-weight: 400;\">, but for people with diabetes, that threshold may be somewhat lower.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Though <\/span><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0002916522010206\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">some studies<\/span><\/a><span style=\"font-weight: 400;\"> suggest caffeine can have a protective effect on insulin resistance, reducing your risk for Type 2 diabetes, the fact that caffeine can affect insulin levels at all means people with diabetes who consume caffeine need to monitor themselves closely&mdash;especially when taking medications like Januvia&mdash;to make sure their blood sugar isn&rsquo;t rising too high or falling too low. (Remember that caffeine is usually consumed in coffee but can also be found in other beverages, like black tea, some sodas, and energy drinks.)<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Like alcohol, the amount of caffeine you can safely consume will be individualized to your body and your diet. A <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6544578\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">2019 study<\/span><\/a><span style=\"font-weight: 400;\"> shows that caffeine may raise blood sugar in the short term while improving glucose levels over time, so caffeinated beverages like coffee may still be part of your daily diet as long as you&rsquo;re not overdoing it.<\/span><\/p>\n<h2 id=\"herbs-and-supplements-to-avoid-with-januvia\"><span style=\"font-weight: 400;\">Herbs and supplements to avoid with Januvia<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Like foods and drinks, there are no reports of over-the-counter herbs or supplements directly interfering with Januvia. Still, several<\/span> <a href=\"https:\/\/diabetes.org\/food-nutrition\/diabetes-vitamins-supplements\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">vitamins and minerals can affect blood sugar levels<\/span><\/a><span style=\"font-weight: 400;\"> and should generally be avoided (or used with caution) if you have Type 2 diabetes.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">You should always talk to your healthcare provider before taking any herbs or vitamins, but people on Januvia should be especially careful about the following supplements:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/ods.od.nih.gov\/factsheets\/Chromium-HealthProfessional\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Chromium<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/heart.bmj.com\/content\/102\/3\/198\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Niacin<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6943541\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Ginseng<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4821002\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">St. John&rsquo;s wort<\/span><\/a><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">These supplements may raise or lower your blood sugar levels, affecting how well Januvia works, or in the case of St. John&rsquo;s wort, may decrease the effectiveness of the drug.<\/span><\/p>\n<h2 id=\"what-should-you-eat-while-taking-januvia\"><span style=\"font-weight: 400;\">What should you eat while taking Januvia?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Because there&rsquo;s no interaction between Januvia and any foods, nothing you eat will help your body better absorb the medication or make it work better. But Dr. Varughese says the ideal foods to eat while taking Januvia are ones with a <\/span><a href=\"https:\/\/www.cancer.gov\/publications\/dictionaries\/cancer-terms\/def\/glycemic-index\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">low glycemic index<\/span><\/a><span style=\"font-weight: 400;\">; these foods raise blood sugar levels slowly and steadily rather than in a dramatic spike.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The most <\/span><a href=\"https:\/\/medlineplus.gov\/ency\/patientinstructions\/000941.htm\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">common low glycemic index foods<\/span><\/a><span style=\"font-weight: 400;\"> include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Barley, oats, and quinoa<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Carrots and leafy green vegetables<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Apples and oranges<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nuts and beans<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lean protein, like chicken, fish, and eggs<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low-fat dairy, including milk, yogurt, and hard cheeses (like cheddar)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Some of these foods can also actively <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/diabetes-diet\/\"><span style=\"font-weight: 400;\">lower blood sugar levels<\/span><\/a><span style=\"font-weight: 400;\">, making them an especially good choice for anyone with Type 2 diabetes.<\/span><\/p>\n<h2 id=\"gastrointestinal-side-effects-of-januvia\"><span style=\"font-weight: 400;\">Gastrointestinal side effects of Januvia<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">All DPP-4 inhibitors can cause mild digestive side effects, says Dr. Kim, including nausea, diarrhea, and abdominal pain. Some <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3687098\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">people also report constipation<\/span><\/a><span style=\"font-weight: 400;\"> or other changes to bowel movements with these drugs, including Januvia.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If you take Januvia, you may not experience digestive problems, but Dr. Kim says it can help to start with a low dose of Januvia and increase gradually, take your medication with food, and stay hydrated. If you&rsquo;re on Januvia and can&rsquo;t keep any food down or become dehydrated, you should contact a healthcare provider as soon as possible.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In addition to GI side effects, the most common side effects of Januvia include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Upper respiratory infection<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stuffy or runny nose<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sore throat<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Headache<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Serious side effects of Januvia include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kidney problems that may require dialysis<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low blood sugar (hypoglycemia), especially when combined with other blood-sugar-reducing medications like sulfonylurea or insulin<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Serious allergic reactions<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Severe joint pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Bullous pemphigoid, a skin reaction causing skin erosion and blistering<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Drug interactions may occur with certain medications. For example, when combined with the diabetes drugs metformin or rosiglitazone, swelling of the hands or legs may occur. It is unknown if Januvia transfers to breast milk, so breastfeeding women should seek medical advice before using the medication.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The primary complications of Januvia are pancreatitis (inflammation of the pancreas) and worsening of congestive heart failure (for people who already have this condition), says Dr. Varughese.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Symptoms of <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/pancreatitis-treatment-and-medications\"><span style=\"font-weight: 400;\">pancreatitis<\/span><\/a><span style=\"font-weight: 400;\"> include abdominal pain, nausea, fever, and weakness. Individuals with the following medical conditions are at greater risk of developing pancreatitis:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">A history of pancreatitis<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High blood triglyceride levels<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Gallstones<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kidney problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">A history of alcoholism<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">If you have <\/span><a href=\"https:\/\/www.cdc.gov\/heart-disease\/about\/heart-failure.html\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">symptoms of heart failure<\/span><\/a><span style=\"font-weight: 400;\">, including any shortness of breath, fast heartbeat, extreme fatigue, weight gain with swelling in the stomach, feet, legs, and ankles, or sudden and severe abdominal pain while taking Januvia, seek emergency medical attention from a healthcare professional.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Some people with diabetes need more than dietary changes and regular exercise to manage the condition. Prescription drugs like Januvia (sitagliptin) can help maintain healthy blood sugar levels. Manufactured by Merck, Januvia is a once-daily tablet that lowers blood sugar when it rises too high (hyperglycemia). Januvia is FDA approved for people with Type 2 [&hellip;]<\/p>\n","protected":false},"author":135,"featured_media":629948,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[10298,8905],"coauthors":[8860],"class_list":["post-629897","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-diabetes","tag-seasonal","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>5 foods to avoid while taking Januvia<\/title>\n<meta name=\"description\" content=\"Learn which five foods to avoid while taking Januvia to enhance its effectiveness and minimize side effects. 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