{"id":629960,"date":"2024-10-02T13:47:07","date_gmt":"2024-10-02T17:47:07","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=629960"},"modified":"2026-01-28T14:09:25","modified_gmt":"2026-01-28T19:09:25","slug":"prednisone-and-antibiotics","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/prednisone-and-antibiotics\/","title":{"rendered":"Can you take prednisone and antibiotics together?"},"content":{"rendered":"

Prednisone<\/span><\/a> is a <\/span>corticosteroid<\/span><\/a> that treats various conditions, such as <\/span>asthma<\/span><\/a>, inflammation responses, and more. It reduces swelling and immune system reactions. Antibiotics, on the other hand, treat bacterial infections.<\/span><\/p>\n

These prescription drugs can usually be taken together safely if they’re prescribed together. Ahead, read need-to-know information about the combination, such as its efficacy, safety, side effects, and interactions.<\/span><\/p>\n

Can you take prednisone and antibiotics together?<\/span><\/h2>\n

Patients are probably good to go with both of these meds. \u201cThese two types of medications are generally safe when taken together,\u201d says <\/span>Dr. Justine Park, MD<\/span>, a board-certified dermatologist at Skin and Beauty Center. (Fun fact: Did you know <\/span>dermatologists prescribe antibiotics more than any other specialty doctor<\/span>?)<\/span><\/p>\n

While combining the two can be safe, there is nuance. \u201cFor example, the body of literature in an acute sinus infection shows that corticosteroids in combination with antibiotics can resolve symptoms more quickly,\u201d says <\/span>Dr. Luke Hentrich, Pharm.D., BCPS<\/span><\/a>, an assistant professor who answered the questions in conjunction with <\/span>Hannah Suber, a Pharm.D. candidate<\/span><\/a>, both at the University of Tennessee\u2019s Health Science Center College of Pharmacy. \u201cHowever, corticosteroids can suppress your natural immune response and should not be taken longer than prescribed for an acute bacterial infection.\u201d<\/span><\/p>\n

While there\u2019s an added level of risk by combining these medications, there\u2019s also an added level of benefit.<\/span><\/p>\n\t\t

\n\t\t\t

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Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t

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Are there any benefits of taking prednisone with antibiotics?<\/span><\/h2>\n

Again, taking prednisone with antibiotics can be extra helpful in the medical treatment of certain conditions. Dr. Park<\/a> mentions the example of poison oak-induced allergic contact dermatitis that gets infected after scratching it, and Dr. Hentrich mentions acute bacterial infections.\u00a0<\/span><\/p>\n

\u201cPrednisone may improve the time to resolution of symptoms,\u201d he clarifies. Research also shows that <\/span>treating some conditions with prednisone and antibiotics leads to faster healing<\/span><\/a>.<\/span><\/p>\n

However, there\u2019s not necessarily a reason to take both otherwise. \u201cThey are used together when needed, but they are used to treat different conditions, so generally they are not used together,\u201d Dr. Park says.\u00a0<\/span><\/p>\n

In fact, taking both can worsen symptoms, according to Dr. Hentrich. \u201cSome patients may be more susceptible to worsening infection depending on their medical conditions, concurrent prescription medications, etc,\u201d he warns. So again, talking with a provider first is a must.<\/span><\/p>\n

Are there any known interactions between prednisone and antibiotics?<\/span><\/h2>\n

Medical staff must take caution when prescribing these medicines. Dr. Park explains why. \u201cIf treating a bacterial infection, we generally would avoid the use of prednisone as it would be undesirable to blunt the body\u2019s natural immune response in fighting an infection,\u201d she says. \u201cHowever, if there is a concomitant inflammatory process, prednisone should be used so the patient can recover quickly.\u201d (\u201cConcomitant inflammatory process\u201d essentially means inflammation and infection exist simultaneously.)<\/span><\/p>\n

Dr. Hentrich expands on how that could be damaging, saying it \u201ccould make the infection more difficult to treat with antibiotics.\u201d He adds, \u201cThis could also be of concern if the patient has a medical condition that requires long-term corticosteroid treatment or places the patient at a higher risk of complicated infections, such as rheumatoid arthritis or cancer.\u201d<\/span><\/p>\n

Additionally, it\u2019s vital to know what interacts badly with prednisone. Drug interactions include <\/span>NSAIDs<\/span><\/a>, diuretics, diabetes medications, estrogen medications, blood thinners, macrolide antibiotics, certain tuberculosis drugs, and more. <\/span>Avoid alcohol<\/span><\/a> while taking this medication, as well, since it can heighten the risk of side effects, such as infections, gastrointestinal problems, blood pressure changes, mood alterations, and more.<\/span><\/p>\n

Before taking this medication, tell a doctor if you have kidney problems, liver cirrhosis, adrenal gland problems, heart failure, high blood pressure (<\/span>hypertension<\/span><\/a>), osteoporosis, blood clots, <\/span>diabetes<\/span><\/a>, thyroid problems, mental health conditions, muscle disorders, a stomach\/bowel illness, or an active infection.<\/span><\/p>\n

Other <\/span>contradictions of prednisone<\/span><\/a> include patients who have had an allergic reaction to prednisone and the presence of systemic fungal infections. Live vaccines should also be avoided if you\u2019re takinglarge, immunosuppressive prednisone doses.<\/span><\/p>\n

How long after taking prednisone can you take antibiotics?\u00a0<\/span><\/h2>\n

The typical <\/span>prednisone dosage<\/span><\/a> for adults is 5 mg to 60 mg a day in tablet or liquid form. The \u201cright\u201d timing varies for each person. \u201cI usually dose prednisone in the morning only, but dosing schedules vary greatly,\u201d Dr. Park says. \u201cAntibiotics are dosed anywhere from daily to four times a day, depending on which antibiotic is prescribed.\u201d\u00a0<\/span><\/p>\n

Dr. Hentrich agrees that the time of day matters to an extent. \u201cBased on prednisone\u2019s mechanism of action, it will work throughout the day, regardless of when the medication is taken, and can be taken at any time with antibiotics,\u201d he says. \u201cHowever, it is best to take prednisone in the morning to prevent the short-term side effects of the medication, which can include jitteriness and insomnia.\u201d<\/span><\/p>\n

Prednisone dosage and antibiotic dosage generally depend on the patient\u2019s weight and any other coexisting medical conditions, Dr. Park says. Further, any steroid use that lasts a long time must be considered, according to Dr. Hentrich (There\u2019s a reminder to pay special attention to the directions that doctors and pharmacists give).<\/span><\/p>\n

You can buy <\/span>prednisone<\/span><\/a> and antibiotics at a reduced cost by using one of <\/span>SingleCare\u2019s prescription discount cards<\/span><\/a>.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Prednisone is a corticosteroid that treats various conditions, such as asthma, inflammation responses, and more. It reduces swelling and immune system reactions. Antibiotics, on the other hand, treat bacterial infections. These prescription drugs can usually be taken together safely if they’re prescribed together. Ahead, read need-to-know information about the combination, such as its efficacy, safety, […]<\/p>\n","protected":false},"author":87,"featured_media":629963,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[814,788,12752],"coauthors":[21001],"class_list":["post-629960","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-drug-interactions","tag-drug-safety","tag-medication-side-effects","wpautop"],"acf":[],"yoast_head":"\nRisks and benefits of using prednisone with antibiotics<\/title>\n<meta name=\"description\" content=\"Is it safe to combine prednisone and antibiotics? 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