{"id":630072,"date":"2024-10-09T20:16:50","date_gmt":"2024-10-10T00:16:50","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=630072"},"modified":"2026-03-25T16:24:28","modified_gmt":"2026-03-25T20:24:28","slug":"naproxen-for-tooth-pain","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/naproxen-for-tooth-pain\/","title":{"rendered":"Is naproxen good for tooth pain?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Naproxen<\/span><span style=\"font-weight: 400;\"> is a generic <\/span><span style=\"font-weight: 400;\">non-steroidal anti-inflammatory drug<\/span><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/nsaids\"><span style=\"font-weight: 400;\">NSAID<\/span><\/a><span style=\"font-weight: 400;\">). It functions as an <\/span><span style=\"font-weight: 400;\">analgesic<\/span><span style=\"font-weight: 400;\"> for <\/span><span style=\"font-weight: 400;\">pain relief<\/span><span style=\"font-weight: 400;\"> and an anti-inflammatory to reduce swelling. These combined effects make it a good choice for most people suffering from <\/span><span style=\"font-weight: 400;\">tooth pain<\/span><span style=\"font-weight: 400;\">. Considering how intense <\/span><span style=\"font-weight: 400;\">dental pain<\/span><span style=\"font-weight: 400;\"> can be, you are sure to benefit from knowing more about <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/naproxen-sodium\"><span style=\"font-weight: 400;\">naproxen<\/span><\/a><span style=\"font-weight: 400;\"> use in this setting, as well as learning about other options.<\/span><\/p>\n\t\t<div id=\"coupon-cta\" class=\"coupon-cta master-template\">\n\t\t\t<p id=\"headline\">Save up to 80% on  Naproxen with SingleCare<\/p>\n\t\t\t<p id=\"subheadline\">Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t<div class=\"details-wrap\">\n\t\t\t\t<div class=\"details\">\n\t\t\t\t\t Naproxen 500 mg (60 Tablets)\t\t\t\t<\/div>\n\t\t\t\t<div class=\"address\">\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"api-response\">\n\t\t\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-kroger.svg\" alt=\"Kroger Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$7.34<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/naproxen#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/naproxen#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-harristeeter.svg\" alt=\"Harris Teeter Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$7.34<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/naproxen#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/naproxen#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/naproxen#blog-cta\" class=\"coupon-see-all-btn\">See  Naproxen prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n<h2 id=\"does-naproxen-help-with-tooth-pain\"><span style=\"font-weight: 400;\">Does <\/span><span style=\"font-weight: 400;\">naproxen<\/span><span style=\"font-weight: 400;\"> help with <\/span><span style=\"font-weight: 400;\">tooth pain<\/span><span style=\"font-weight: 400;\">?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Typical <\/span><span style=\"font-weight: 400;\">dental pain<\/span><span style=\"font-weight: 400;\"> arises from a nerve that has become exposed or compressed due to infection or <\/span><span style=\"font-weight: 400;\">dental procedures<\/span><span style=\"font-weight: 400;\">. Like other <\/span><span style=\"font-weight: 400;\">NSAIDs<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">naproxen<\/span><span style=\"font-weight: 400;\"> can alleviate this pain by inhibiting cyclooxygenase <\/span><span style=\"font-weight: 400;\">enzymes<\/span><span style=\"font-weight: 400;\">, which propagate the inflammatory cycle. Quick <\/span><span style=\"font-weight: 400;\">pain relief<\/span><span style=\"font-weight: 400;\"> can follow, and as swelling around the nerve dissipates, further reduction in discomfort can be realized.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Naproxen<\/span><span style=\"font-weight: 400;\"> has been put to the test for this use. A <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8269451\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">randomized, double-blind, placebo-controlled study<\/span><\/a><span style=\"font-weight: 400;\"> demonstrated its effectiveness in <\/span><span style=\"font-weight: 400;\">postoperative dental pain<\/span><span style=\"font-weight: 400;\">. <\/span><span style=\"font-weight: 400;\">Naproxen<\/span><span style=\"font-weight: 400;\"> even seemed a little better than <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> in the study, a finding that was duplicated in a <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31402718\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">study<\/span><\/a><span style=\"font-weight: 400;\"> comparing the two <\/span><span style=\"font-weight: 400;\">NSAIDs<\/span><span style=\"font-weight: 400;\"> for <\/span><span style=\"font-weight: 400;\">dental pain<\/span><span style=\"font-weight: 400;\">. The superiority of <\/span><span style=\"font-weight: 400;\">naproxen<\/span><span style=\"font-weight: 400;\"> in these clinical trials is based on its longer <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=8bff5df5-d856-4237-b6a8-ae445b454844\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">duration of action<\/span><\/a><span style=\"font-weight: 400;\">, lasting up to 12 hours, compared to <\/span><span style=\"font-weight: 400;\">ibuprofen,<\/span><span style=\"font-weight: 400;\"> which can wear off in 6 hours.<\/span><\/p>\n<h2 id=\"how-fast-does-naproxen-work-for-tooth-pain\"><span style=\"font-weight: 400;\">How fast does <\/span><span style=\"font-weight: 400;\">naproxen<\/span><span style=\"font-weight: 400;\"> work for <\/span><span style=\"font-weight: 400;\">tooth pain<\/span><span style=\"font-weight: 400;\">?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Coupling an extended duration of analgesia with relatively fast relief would make for an ideal <\/span><span style=\"font-weight: 400;\">pain medication<\/span><span style=\"font-weight: 400;\">. <\/span><span style=\"font-weight: 400;\">Naproxen<\/span><span style=\"font-weight: 400;\"> gets to work in about 30 to 60 minutes for <\/span><span style=\"font-weight: 400;\">tooth pain<\/span><span style=\"font-weight: 400;\">, which puts it in the same ballpark as <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\">, known commonly by <\/span><span style=\"font-weight: 400;\">brand names<\/span> <a href=\"https:\/\/www.singlecare.com\/prescription\/advil\"><span style=\"font-weight: 400;\">Advil<\/span><\/a><span style=\"font-weight: 400;\"> or <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/motrin-ib\"><span style=\"font-weight: 400;\">Motrin<\/span><\/a><span style=\"font-weight: 400;\">. Time to onset of action is fairly consistent amongst different individuals. It is the duration of action that varies mores, being extended in those with kidney disease in particular.<\/span><\/p>\n<h2 id=\"naproxen-dosage-for-tooth-pain\"><span style=\"font-weight: 400;\">Naproxen<\/span><span style=\"font-weight: 400;\"> dosage for <\/span><span style=\"font-weight: 400;\">tooth pain<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Naproxen<\/span><span style=\"font-weight: 400;\"> can be obtained <\/span><span style=\"font-weight: 400;\">over-the-counter<\/span><span style=\"font-weight: 400;\"> at a 220 mg dose, including generic forms and <\/span><span style=\"font-weight: 400;\">brand-name<\/span> <a href=\"https:\/\/www.singlecare.com\/prescription\/aleve\"><span style=\"font-weight: 400;\">Aleve<\/span><\/a><span style=\"font-weight: 400;\">. With a prescription, <\/span><span style=\"font-weight: 400;\">naproxen<\/span><span style=\"font-weight: 400;\"> comes in 250 mg, 375 mg, 500 mg, and 550 mg tablets. <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/naprosyn\"><span style=\"font-weight: 400;\">Naprosyn<\/span><\/a><span style=\"font-weight: 400;\"> is a <\/span><span style=\"font-weight: 400;\">brand-name<\/span><span style=\"font-weight: 400;\"> product.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Between 220 mg and 500 mg per dose is typically taken every 12 hours as needed. Repeat doses can be taken every 12 hours. The maximum daily dose is listed as 1 g usually, but up to 1.5 g per day has been reported for some indications.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Naproxen<\/span><span style=\"font-weight: 400;\"> can also be found in delayed release tablets containing 375 mg, 500 mg or 750 mg. This formulation permits convenient once-daily dosing. <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/ec-naprosyn\"><span style=\"font-weight: 400;\">EC-Naprosyn<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/ec-naproxen\"><span style=\"font-weight: 400;\">EC-<\/span><span style=\"font-weight: 400;\">Naproxen<\/span><\/a><span style=\"font-weight: 400;\">, and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/naprelan\"><span style=\"font-weight: 400;\">Naprelan<\/span><\/a><span style=\"font-weight: 400;\"> are <\/span><span style=\"font-weight: 400;\">brand-names<\/span><span style=\"font-weight: 400;\"> of the extended-release version. Remember your free <\/span><a href=\"https:\/\/www.singlecare.com\/prescription-discount-card\"><span style=\"font-weight: 400;\">SingleCare discount card<\/span><\/a><span style=\"font-weight: 400;\"> if you are interested in a lower price.<\/span><\/p>\n<h2 id=\"naproxen-alternatives-for-tooth-pain\"><span style=\"font-weight: 400;\">Naproxen<\/span><span style=\"font-weight: 400;\"> alternatives for <\/span><span style=\"font-weight: 400;\">tooth pain<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Naproxen<\/span><span style=\"font-weight: 400;\"> is only one member of the <\/span><span style=\"font-weight: 400;\">NSAID<\/span><span style=\"font-weight: 400;\"> family. As we have discussed, <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> is another option, albeit one with a shorter duration of action than <\/span><span style=\"font-weight: 400;\">naproxen<\/span><span style=\"font-weight: 400;\">. <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/meloxicam\/what-is\"><span style=\"font-weight: 400;\">Meloxicam<\/span><\/a><span style=\"font-weight: 400;\"> is an <\/span><span style=\"font-weight: 400;\">NSAID<\/span><span style=\"font-weight: 400;\"> that <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/meloxicam-vs-naproxen\/\"><span style=\"font-weight: 400;\">lasts even longer than <\/span><span style=\"font-weight: 400;\">naproxen<\/span><\/a><span style=\"font-weight: 400;\">, allowing it to be dosed only once daily. It outperformed another <\/span><span style=\"font-weight: 400;\">NSAID<\/span><span style=\"font-weight: 400;\">, diclofenac, in a <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4765749\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">head-to-head comparison study<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Meloxicam is more selective in inhibiting the cyclooxygenase-2 (COX-2) <\/span><span style=\"font-weight: 400;\">enzyme<\/span><span style=\"font-weight: 400;\">. Less inhibition of cyclooxygenase-1 (COX-1) <\/span><span style=\"font-weight: 400;\">enzyme<\/span><span style=\"font-weight: 400;\"> is thought to translate to less <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/naproxen-side-effects\/\"><span style=\"font-weight: 400;\">side effects<\/span><\/a><span style=\"font-weight: 400;\"> like bleeding and stomach ulcers. This characteristic could make meloxicam a better choice than <\/span><span style=\"font-weight: 400;\">naproxen<\/span><span style=\"font-weight: 400;\"> for those at higher risk of gastrointestinal adverse effects. However, if this is a concern, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/celebrex\"><span style=\"font-weight: 400;\">Celebrex<\/span><\/a><span style=\"font-weight: 400;\"> (celecoxib) is truly a <\/span><a href=\"https:\/\/my.clevelandclinic.org\/health\/drugs\/23119-cox-2-inhibitors\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">selective COX-2 <\/span><span style=\"font-weight: 400;\">inhibitor<\/span><\/a><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">NSAID<\/span><span style=\"font-weight: 400;\"> that could be safer for the stomach than meloxicam or <\/span><span style=\"font-weight: 400;\">naproxen<\/span><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Stepping away from <\/span><span style=\"font-weight: 400;\">NSAIDs<\/span><span style=\"font-weight: 400;\"> altogether could be necessary. People with a history of bleeding, kidney disease, or heart disease may be at too much risk from <\/span><span style=\"font-weight: 400;\">NSAID<\/span> <span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\">. Another example is a patient taking <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/anticoagulants\"><span style=\"font-weight: 400;\">anticoagulants<\/span><\/a><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">blood thinners<\/span><span style=\"font-weight: 400;\">, which create an untenable bleeding risk when <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/naproxen-interactions\/\"><span style=\"font-weight: 400;\">combined with <\/span><span style=\"font-weight: 400;\">NSAIDs<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/tylenol\"><span style=\"font-weight: 400;\">Tylenol<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/acetaminophen\/what-is\"><span style=\"font-weight: 400;\">acetaminophen<\/span><\/a><span style=\"font-weight: 400;\">) may be a safer option than <\/span><span style=\"font-weight: 400;\">naproxen<\/span><span style=\"font-weight: 400;\">, or any <\/span><span style=\"font-weight: 400;\">NSAID<\/span><span style=\"font-weight: 400;\"> for that matter, for folks with underlying renal or cardiovascular health conditions or at risk for bleeding. It is among the recommended <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/best-painkiller-for-tooth-nerve-pain\/\"><span style=\"font-weight: 400;\">painkillers<\/span><span style=\"font-weight: 400;\"> for acute and <\/span><span style=\"font-weight: 400;\">postoperative dental pain<\/span><\/a><span style=\"font-weight: 400;\">, according to <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7192823\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">a <\/span><span style=\"font-weight: 400;\">systematic review<\/span><span style=\"font-weight: 400;\"> on the subject<\/span><\/a><span style=\"font-weight: 400;\">. High doses of <\/span><span style=\"font-weight: 400;\">acetaminophen<\/span><span style=\"font-weight: 400;\"> can be harmful to the liver, so limited dosing is necessary. Avoidance may be best amongst those with liver disease and heavy alcohol use.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Lastly, <\/span><span style=\"font-weight: 400;\">opioids<\/span><span style=\"font-weight: 400;\"> are also listed in the aforementioned topic review. Members of this drug class include <\/span><span style=\"font-weight: 400;\">hydrocodone<\/span><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/oxycodone-hcl\/what-is\"><span style=\"font-weight: 400;\">oxycodone<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/codeine-sulfate\/what-is\"><span style=\"font-weight: 400;\">codeine<\/span><\/a><span style=\"font-weight: 400;\">, and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/tramadol-hcl\/what-is\"><span style=\"font-weight: 400;\">tramadol<\/span><\/a><span style=\"font-weight: 400;\">. Although they are often considered the most potent <\/span><span style=\"font-weight: 400;\">painkillers<\/span><span style=\"font-weight: 400;\">, in reality, <\/span><span style=\"font-weight: 400;\">NSAIDs<\/span><span style=\"font-weight: 400;\"> like <\/span><span style=\"font-weight: 400;\">naproxen<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> are more effective. Opiate <\/span><span style=\"font-weight: 400;\">analgesics<\/span><span style=\"font-weight: 400;\"> carry a risk of vomiting, constipation, respiratory depression, dependence, and addiction. Based on these adverse effects and lower efficacy, they have become less commonly prescribed.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Combining <\/span><span style=\"font-weight: 400;\">pain relievers<\/span><span style=\"font-weight: 400;\"> from different categories may be a good option. <\/span><span style=\"font-weight: 400;\">Naproxen<\/span><span style=\"font-weight: 400;\"> is an effective <\/span><span style=\"font-weight: 400;\">analgesic<\/span><span style=\"font-weight: 400;\"> for <\/span><span style=\"font-weight: 400;\">acute dental pain<\/span><span style=\"font-weight: 400;\">, but if additional relief is needed, <\/span><span style=\"font-weight: 400;\">acetaminophen<\/span><span style=\"font-weight: 400;\"> could be added in some cases. Opiates could also be used in tandem with <\/span><span style=\"font-weight: 400;\">NSAIDs<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">acetaminophen<\/span><span style=\"font-weight: 400;\"> in extreme cases.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Keep in mind that as medication doses and numbers increase, so does the risk of adverse reactions. Ask your <\/span><span style=\"font-weight: 400;\">healthcare<\/span><span style=\"font-weight: 400;\"> provider for <\/span><span style=\"font-weight: 400;\">medical advice<\/span><span style=\"font-weight: 400;\"> about which <\/span><span style=\"font-weight: 400;\">painkiller<\/span><span style=\"font-weight: 400;\"> is right for you. They will need to take into account your medical history and your list of prescription meds, <\/span><span style=\"font-weight: 400;\">over-the-counter<\/span><span style=\"font-weight: 400;\"> drugs, and supplements to give you the best recommendation.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Naproxen is a generic non-steroidal anti-inflammatory drug (NSAID). It functions as an analgesic for pain relief and an anti-inflammatory to reduce swelling. These combined effects make it a good choice for most people suffering from tooth pain. Considering how intense dental pain can be, you are sure to benefit from knowing more about naproxen use [&hellip;]<\/p>\n","protected":false},"author":137,"featured_media":630073,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[10708],"coauthors":[20732],"class_list":["post-630072","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-over-the-counter-medications","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Does naproxen help with tooth pain?<\/title>\n<meta name=\"description\" content=\"Naproxen can be used for tooth pain and has been shown to have a longer duration of action than ibuprofen. 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