{"id":630274,"date":"2024-11-04T13:22:29","date_gmt":"2024-11-04T18:22:29","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=630274"},"modified":"2026-01-28T14:08:34","modified_gmt":"2026-01-28T19:08:34","slug":"prempro-without-insurance","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/prempro-without-insurance\/","title":{"rendered":"How much is Prempro without insurance?"},"content":{"rendered":"

Prempro is an oral tablet containing equine conjugated estrogens and medroxyprogesterone acetate (MPA). The hormonal drug is used for the relief of vasomotor symptoms of <\/span>menopause<\/span><\/a>, which are more commonly known as hot flashes. To the majority of menopausal women experiencing hot flashes, which can be very disruptive to sleep or daily life, the availability of effective therapy is welcome news. Unfortunately, the price of Prempro without insurance, at $320 for a 28-day pill pack, can be problematic. We will detail the drug\u2019s cost and delve into ways to save on Prempro<\/span><\/p>\n

Related: <\/b>Prempro coupon<\/b><\/a> | <\/b>Prempro details<\/b><\/a><\/p>\n

Is Prempro covered by insurance?<\/span><\/h2>\n

If you have prescription drug coverage through your health insurance plan, the drug <\/span>formulary<\/span><\/a> for the plan can tell you whether Prempro is covered. As a brand-name medicine, Prempro is not always covered or listed as a preferred option, meaning that your <\/span>copay<\/span><\/a> could be high even if it is covered. Check your prescription coverage in a similar manner if you have <\/span>Medicare<\/span><\/a>.<\/span><\/p>\n

Aetna\u2019s Standard Plan<\/span><\/a> covers Prempro under the category of preferred brand-name drugs, but <\/span>Humana\u2019s Medicare formulary<\/span><\/a> does not cover Prempro. These are only examples of how coverage can differ between insurance plans. You will need to refer to your formulary and check with your pharmacist to see if you have coverage and what your copay for Prempro will be.<\/span><\/p>\n

How much does Prempro cost without insurance?<\/span><\/h2>\n

Without insurance, Prempro pricing can be steep. A 28-day pack of Prempro tablets retails for $320, over $11 per pill. That means that every year of treatment will cost about $3800. Keep in mind that the price tag will be different from one pharmacy to the next.<\/span><\/p>\n

Relief from hot flashes may be worth the expense, but you are right to wonder if relief could come at a more palatable price. Unfortunately, there is no generic version of Prempro. Pricing of the drug is similar among its different dose options<\/a>, which are 0.3-1.5 mg, 0.45-1.5mg, 0.625-2.5 mg, and 0.625-5 mg of conjugated estrogens and MPA.<\/span><\/p>\n

Savings can be had, even if the generic is unavailable and dosing adjustments don\u2019t help. The answer could come in the form of an alternative menopausal hormone therapy. Mimvey and Jinteli, for instance, have generic versions that cost a lot less. Either of them can be purchased with a SingleCare coupon for about $20 for a one-month supply.<\/span><\/p>\n

Choosing between menopausal hormone therapies depends on a number of factors other than expense and analysis of patient-specific information will be needed when you discuss this with your healthcare provider. If you have had a hysterectomy, neither Prempro nor any of the combination <\/span>estrogen<\/span><\/a> and <\/span>progesterone<\/span><\/a> products in the following table are typically recommended, and instead, an estrogen product alone is advised. On the contrary, estrogens alone are not used in people with a uterus due to the risk of endometrial hyperplasia or thickening of the uterine lining.<\/span><\/p>\n

Addressing different menopausal issues could be a distinguishing factor. For example, genitourinary symptoms of menopause, such as vaginal dryness and painful intercourse, may be best addressed with a topical estrogen cream like <\/span>Premarin<\/span><\/a> rather than combination tablets like Prempro. Osteoporosis treatment involves strengthening weak bones, and Prempro is capable of doing so, but it and its fellow menopausal hormone therapies are not commonly recommended options for this purpose.<\/span><\/p>\n

If a woman has just <\/span>recently entered menopause<\/span><\/a>, Prempro could be associated with breakthrough vaginal bleeding. A cyclic alternative like Premphase for the first couple of years may be preferred by inducing predictable menstruation. The price of Prempro and Premphase are similar.<\/span><\/p>\n

Side effects<\/span><\/a> are always a consideration when choosing between drug options, and therapy for menopausal symptoms is no different. Blood clots, uterine and breast cancer, heart attack, and stroke are among the most feared adverse reactions, even if they are not among the common side effects. Carefully choosing a formulation and dose is essential to do with the medical advice of your healthcare professionals. Price is not a major distinguishing factor between most of the different combination products with estrogen and progesterone.\u00a0<\/span><\/p>\n

The method of drug delivery is another consideration when picking the right menopausal hormone therapy. Applying a patch once or twice weekly may be preferred over a daily tablet. As you can see from the prices in the following table, savings are not a factor that will sway you toward the transdermal drug option.<\/span><\/p>\n

RELATED: <\/b>Prempro alternatives: What can I take instead of Prempro?<\/b><\/a><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Compare Prempro prices to related drugs<\/span><\/th>\n<\/tr>\n<\/thead>\n
Drug name<\/b><\/td>\nPrice without insurance of brand-name drug\u00a0<\/b><\/td>\nSingleCare price<\/b><\/td>\nSavings options<\/b><\/td>\n<\/tr>\n
Prempro<\/span><\/a><\/p>\n

(equine conjugated estrogens and medroxyprogesterone acetate)<\/span><\/td>\n

$320 per 1, 28-pill pack<\/span><\/td>\n$220 per 1, 28-pill pack of brand-name Prempro<\/span><\/td>\nSee updated prices<\/span><\/a><\/td>\n<\/tr>\n
Premphase<\/span><\/a> (equine conjugated estrogens and medroxyprogesterone acetate)<\/span><\/td>\n$290 per 1, 28-pill pack<\/span><\/td>\n$220 per 1, 28-pill pack\u00a0 of brand-name Premphase<\/span><\/td>\nSee updated prices<\/span><\/a><\/td>\n<\/tr>\n
Bijuva<\/span><\/a> (estrogen and progesterone)<\/span><\/td>\n$360 per 1, 30-pill pack<\/span><\/td>\n$225 per 1, 30-pill pack of brand-name Premphase<\/span><\/td>\nSee updated prices<\/span><\/a><\/td>\n<\/tr>\n
Mimvey<\/span><\/a> (<\/span>estradiol and norethindrone<\/span><\/a>)<\/span><\/td>\n$140 per 1, 28-pill pack<\/span><\/td>\n$23 per 1, 28-pill pack of generic estradiol and norethindrone<\/span><\/td>\nSee updated prices<\/span><\/a><\/td>\n<\/tr>\n
Angeliq<\/span><\/a> (estradiol and drospirenone)<\/span><\/td>\n$240 per 1, 28-pill pack<\/span><\/td>\n$190 per 1, 28-pill pack of brand-name Angeliq<\/span><\/td>\nSee updated prices<\/span><\/a><\/td>\n<\/tr>\n
Jinteli<\/span><\/a> (<\/span>ethinyl estradiol and norethindrone<\/span><\/a>)<\/span><\/td>\n$90 per 1, 28-pill pack<\/span><\/td>\n$15 per 1, 28-pill pack of generic ethinyl estradiol and norethindrone<\/span><\/td>\nSee updated prices<\/span><\/a><\/td>\n<\/tr>\n
Climara Pro<\/span><\/a> (estradiol and levonorgestrel) patch<\/span><\/td>\n$330 per 1, 4-patch pack of once-weekly patches<\/span><\/td>\n$240 per 1, 4-patch pack of once-weekly patches of brand-name Climara Pro<\/span><\/td>\nSee updated prices<\/span><\/a><\/td>\n<\/tr>\n
CombiPatch<\/span><\/a> (estradiol and norethindrone)<\/span><\/td>\n$390 per 1, 8-patch pack of twice-weekly patches<\/span><\/td>\n$240 per 1, 8-patch pack of twice-weekly patches of brand-name Combipatch<\/span><\/td>\nSee updated prices<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Prescription drug prices often change. These are the most accurate medication prices at the time of publishing. The listed price without insurance references the price of brand-name drugs. The listed SingleCare price references the price of generic drugs if available. Click the link under \u201cSavings options\u201d to see updated drug prices.<\/span><\/i><\/p>\n

How to get Prempro without insurance<\/span><\/h2>\n

We can break down a savings plan into a number of options. To start with, if you have health insurance and prescription coverage, checking your formulary for Prempro inclusion and copay requirements is the first step.\u00a0<\/span><\/p>\n

The manufacturer Pfizer does not include Prempro among the drugs in its copay savings plan. However, Pfizer does have the <\/span>Rx Pathways program<\/span><\/a> to help eligible individuals without insurance or with Medicare coverage. Pharmaceutical company patient assistance programs have eligibility criteria that must be met to participate. Here are some more widely inclusive ways to save.<\/span><\/p>\n

1. Get a SingleCare discount card<\/span><\/h3>\n

SingleCare discount cards<\/span><\/a> are free; you just need to show them to your pharmacist to get the savings started. Instead of $320 for a one-month supply of 28 Prempro tablets, you can pay just approximately $220 with the discount card.\u00a0<\/span><\/p>\n

2. Shop around at different pharmacies<\/span><\/h3>\n

Do not overlook the benefits of shopping around. Pharmacies can have widely different prices for the same medicines. SingleCare coupons are accepted at over 35,000 pharmacies in the United States; this means you\u2019ve got options for Prempro savings. With a SingleCare coupon, the discount price on Prempro can range from $220 to $270 for a 1, 28-pill pack. That is a $50 difference, depending on which pharmacy you use.<\/span><\/p>\n

3. Consider other medications for hot flashes<\/span><\/h3>\n

As detailed in the table above, there are a number of other combination estrogen and progesterone products for menopausal hormone therapy, previously referred to as hormone replacement therapy. Relief from hot flashes can be a striking benefit of any of these alternatives, but the risks have to be reviewed.\u00a0<\/span><\/p>\n

Your primary care provider or gynecologist can go over the pros and cons of each option with you. If you and your provider agree that they suit your needs, generic Mimvey and generic Jinteli offer substantial savings.<\/span><\/p>\n

4. Ask about alternatives to hormones<\/span><\/h3>\n

Hormones are not always the best pick for treating the vasomotor symptoms of menopause. <\/span>Effexor XR<\/span><\/a> (venlafaxine), <\/span>Neurontin<\/span><\/a> (gabapentin), and <\/span>Veozah<\/span><\/a> (fexolinetant) are non-hormonal prescription medicines that can be used to control hot flashes. <\/span>Dietary adjustments<\/span><\/a> can even help. If there is a contraindication to Prempro and other hormone therapies, like a history of blood clots or breast cancer, these alternatives could be something to speak to your medical team about.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Prempro is an oral tablet containing equine conjugated estrogens and medroxyprogesterone acetate (MPA). The hormonal drug is used for the relief of vasomotor symptoms of menopause, which are more commonly known as hot flashes. 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That\u2019s approximately $3800 a year. Here's how to save.","breadcrumb":{"@id":"https:\/\/www.singlecare.com\/blog\/prempro-without-insurance\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.singlecare.com\/blog\/prempro-without-insurance\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.singlecare.com\/blog\/prempro-without-insurance\/#primaryimage","url":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2024\/11\/Prempro-without-insurance.png","contentUrl":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2024\/11\/Prempro-without-insurance.png","width":1920,"height":1080,"caption":"Spilled pill bottle representing the medication Prempro"},{"@type":"BreadcrumbList","@id":"https:\/\/www.singlecare.com\/blog\/prempro-without-insurance\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.singlecare.com\/blog\/"},{"@type":"ListItem","position":2,"name":"How much is Prempro without insurance?"}]},{"@type":"WebSite","@id":"https:\/\/www.singlecare.com\/blog\/#website","url":"https:\/\/www.singlecare.com\/blog\/","name":"The Checkup, a health blog by SingleCare","description":"Read the latest in prescription, wellness, and healthcare news","publisher":{"@id":"https:\/\/www.singlecare.com\/blog\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.singlecare.com\/blog\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.singlecare.com\/blog\/#organization","name":"SingleCare","url":"https:\/\/www.singlecare.com\/blog\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.singlecare.com\/blog\/#\/schema\/logo\/image\/","url":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2020\/01\/placeholderimage-1.jpg","contentUrl":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2020\/01\/placeholderimage-1.jpg","width":1200,"height":630,"caption":"SingleCare"},"image":{"@id":"https:\/\/www.singlecare.com\/blog\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/singlecare","https:\/\/x.com\/SingleCare","https:\/\/www.instagram.com\/singlecare\/?hl=en","https:\/\/www.linkedin.com\/company\/singlecare\/","https:\/\/www.youtube.com\/channel\/UCd9kiPIjCQw95-2BHCYePKA"]},{"@type":"Person","@id":"https:\/\/www.singlecare.com\/blog\/#\/schema\/person\/169a1d8c8b88282cc3b792a394fc3575","name":"Janice Rodden","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/52a9a50886f8a50207b3817add6cf041e73c89f3a5b1776ee5f9642e519a0611?s=96&d=mm&r=gd66250315c656457c96a08c8fc87b6bb","url":"https:\/\/secure.gravatar.com\/avatar\/52a9a50886f8a50207b3817add6cf041e73c89f3a5b1776ee5f9642e519a0611?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/52a9a50886f8a50207b3817add6cf041e73c89f3a5b1776ee5f9642e519a0611?s=96&d=mm&r=g","caption":"Janice Rodden"},"url":"https:\/\/www.singlecare.com\/blog\/author\/jrodden\/"}]}},"_links":{"self":[{"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/posts\/630274","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/users\/85"}],"replies":[{"embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/comments?post=630274"}],"version-history":[{"count":0,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/posts\/630274\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/media\/630275"}],"wp:attachment":[{"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/media?parent=630274"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/categories?post=630274"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/tags?post=630274"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/coauthors?post=630274"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}