{"id":630307,"date":"2024-11-05T19:29:11","date_gmt":"2024-11-06T00:29:11","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=630307"},"modified":"2024-11-05T19:29:11","modified_gmt":"2024-11-06T00:29:11","slug":"hydroxyzine-for-cats","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/hydroxyzine-for-cats\/","title":{"rendered":"Can I give my cat hydroxyzine?"},"content":{"rendered":"<p><a href=\"https:\/\/www.singlecare.com\/prescription\/hydroxyzine-hcl\"><span style=\"font-weight: 400;\">Hydroxyzine<\/span><\/a><span style=\"font-weight: 400;\"> is a prescription <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/antihistamines\"><span style=\"font-weight: 400;\">antihistamine<\/span><\/a><span style=\"font-weight: 400;\"> used to treat contact dermatitis and other allergic reactions in cats. It is safe for cats but is less effective in cats than people. It works best when administered before the cat is exposed to a reaction-inducing event like a vaccine shot. Vets are more likely to use it long-term to prevent itchy skin due to contact allergies. However, cats develop tolerance to the drug over time, making it less effective. When an antihistamine is called for, a veterinarian may choose to use <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/cetirizine-hcl\"><span style=\"font-weight: 400;\">cetirizine<\/span><\/a><span style=\"font-weight: 400;\">, a common over-the-counter antihistamine. Cetirizine is an active form of hydroxyzine but is less likely to have sedative side effects.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/prescription\/hydroxyzine-hcl\"><b>Save up to 80% on hydroxyzine<\/b><\/a><\/p>\n<h2 id=\"what-is-hydroxyzine-used-for-in-cats\"><span style=\"font-weight: 400;\">What is hydroxyzine used for in cats?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Hydroxyzine is not a common cat drug and has not been approved by the FDA for use in animals. In cats, there are recommended hydroxyzine dosages as an antihistamine or as a treatment for itchy skin (pruritus) due to allergic reactions.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Though doses aren\u2019t standardized, veterinarians could use hydroxyzine as a sedative before vet visits or veterinary procedures. Hydroxyzine is FDA-approved for use as a sedative in people.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Hydroxyzine is also used as an anti-anxiety medication in people because of its sedative effects. Veterinarians may choose to use it this way, but it\u2019s not tested or recommended as an <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/anxiolytics\"><span style=\"font-weight: 400;\">anti-anxiety medication<\/span><\/a><span style=\"font-weight: 400;\"> in animals.<\/span><\/p>\n<h3 id=\"sensitivity-reactions\"><span style=\"font-weight: 400;\">Sensitivity reactions\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Tissues produce histamines in response to emergencies like injuries or parasites. They are powerful instigators of inflammation and start the process that produces swelling, redness, itching, pain, lowered blood pressure, and other symptoms associated with infections, injuries, and allergic reactions. Antihistamines like hydroxyzine block the actions of histamines to relieve inflammation and its related ills.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Cats also generate histamines in response to allergens, infections, or injuries, but they play less of a role in inflammation in a cat\u2019s body than in a person. Antihistamines are less effective at treating symptoms like itchy skin. There is some doubt that they are effective in quelling acute inflammation in a cat.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Still, antihistamines like hydroxyzine can help relieve some symptoms, but in a more limited way than in people. Hydroxyzine and other antihistamines may work best when given before the cat is exposed to something that would provoke a reaction, such as a vaccination. It is more common for veterinarians to prescribe hydroxyzine as a long-term prevention.\u00a0<\/span><\/p>\n<h3 id=\"itchy-skin\"><span style=\"font-weight: 400;\">Itchy skin<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Veterinarians most commonly use hydroxyzine in cats with itchy skin due to contact allergies (atopic dermatitis).\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Allergic reactions, hives, food allergies, flea bites, and insect bites can cause itchy skin in cats. The <\/span><a href=\"https:\/\/todaysveterinarypractice.com\/dermatology\/feline-atopic-skin-syndrome\/\"><span style=\"font-weight: 400;\">most common feline skin condition<\/span><\/a><span style=\"font-weight: 400;\"> treated by veterinarians is feline atopic skin syndrome (FASS), a chronic, itchy condition caused by sensitivity reactions to environmental allergens.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Again, antihistamines like hydroxyzine are not as effective at treating itchy skin in cats as they are treating people or dogs with itchy skin. Instead, veterinarians turn first to <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/corticosteroids\"><span style=\"font-weight: 400;\">corticosteroids<\/span><\/a><span style=\"font-weight: 400;\"> like <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/prednisolone\"><span style=\"font-weight: 400;\">prednisolone<\/span><\/a><span style=\"font-weight: 400;\"> or <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/dexamethasone\"><span style=\"font-weight: 400;\">dexamethasone<\/span><\/a><span style=\"font-weight: 400;\">. However, because steroids involve unpleasant side effects, a veterinarian may use hydroxyzine <\/span><a href=\"https:\/\/veterinarypartner.vin.com\/default.aspx?pid=19239&amp;id=4951437\"><span style=\"font-weight: 400;\">as a preventive treatment<\/span><\/a><span style=\"font-weight: 400;\"> for itchy skin to reduce the burden of corticosteroid treatment.\u00a0<\/span><\/p>\n<h2 id=\"is-hydroxyzine-safe-for-cats\"><span style=\"font-weight: 400;\">Is hydroxyzine safe for cats?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">When given under the direction of a veterinarian, hydroxyzine is safe for cats as a symptom-relief medication.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Hydroxyzine should never be given to cats that have had an allergic reaction to hydroxyzine or <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/cetirizine-hcl\/what-is\"><span style=\"font-weight: 400;\">cetirizine<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><a href=\"https:\/\/dogcatdoc.com\/wp-content\/uploads\/2021\/05\/VMG-Hydroxyzine.pdf\"><span style=\"font-weight: 400;\">Veterinarians are advised<\/span><\/a><span style=\"font-weight: 400;\"> not to give hydroxyzine to cats with:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Bladder obstruction<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/congestive-heart-failure-treatment-and-medications\"><span style=\"font-weight: 400;\">Heart failure<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Severe heart disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stomach obstruction<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Veterinarians will use hydroxyzine cautiously in cats that have:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Urination problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Enlarged prostate<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kidney disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Liver disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heart disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Thyroid problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/glaucoma-treatment-and-medications\"><span style=\"font-weight: 400;\">Glaucoma<\/span><\/a><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Hydroxyzine is also used with caution in older, pregnant, or breastfeeding cats.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Hydroxyzine can cause birth defects when used in a pregnant cat. Veterinarians do not know if hydroxyzine is present in a cat\u2019s breast milk. If it is, it could cause problems in nursing kittens.<\/span><\/p>\n<h3 id=\"side-effects-of-hydroxyzine-in-cats\"><span style=\"font-weight: 400;\">Side effects of hydroxyzine in cats<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">In cats, the most common side effects of hydroxyzine are:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sleepiness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Depression<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Increased thirst<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Over-excitement\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Behavioral changes<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Hydroxyzine may also cause dry mouth, though this side effect is more common in dogs. Make sure the cat has uninterrupted access to a filled water bowl.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Contact a veterinarian if any of these side effects worsen.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The most serious side effects a cat may experience are allergic reactions to the drug. Immediately contact a veterinarian or veterinary hospital if a cat shows signs of a hypersensitivity reaction.\u00a0<\/span><\/p>\n<h3 id=\"interactions-of-hydroxyzine-with-other-pet-meds\"><span style=\"font-weight: 400;\">Interactions of hydroxyzine with other pet meds<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">To avoid possible drug interactions, tell the veterinarian about all the drugs, supplements, and herbal remedies the cat is being given, particularly:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Other antihistamines<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Drugs that make the cat sleepy, such as narcotic pain relievers, <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/barbiturates\"><span style=\"font-weight: 400;\">barbiturates<\/span><\/a><span style=\"font-weight: 400;\">, tranquilizers, or similar CNS depressants<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Drugs that treat <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/asthma-treatment-and-medications\"><span style=\"font-weight: 400;\">asthma<\/span><\/a><span style=\"font-weight: 400;\"> (inhalers), vomiting, digestive system problems, or overactive bladder called <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/muscarinic-antagonists\"><span style=\"font-weight: 400;\">anticholinergic drugs<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/epinephrine\"><span style=\"font-weight: 400;\">Epinephrine<\/span><\/a><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Pet owners who give their cat CBD should talk to the veterinarian before starting the cat on hydroxyzine. CBD may worsen many of the sedative side effects of hydroxyzine, such as sleepiness, fatigue, and depression.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">All antihistamines can significantly distort the results of allergy tests. Cats that are scheduled for a skin allergy test should not take antihistamines three to seven days before the test.<\/span><\/p>\n<h2 id=\"hydroxyzine-dosage-for-cats\"><span style=\"font-weight: 400;\">Hydroxyzine dosage for cats<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The standard hydroxyzine dosage for cats is <\/span><a href=\"https:\/\/www.aaha.org\/resources\/2023-aaha-management-of-allergic-skin-diseases-in-dogs-and-cats-guidelines\/table-8-oral-antihistamine-doses-for-cats\/\"><span style=\"font-weight: 400;\">5\u201310 mg, given every 12 hours<\/span><\/a><span style=\"font-weight: 400;\"> either as an antihistamine or a treatment for itching.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The veterinarian can prescribe either human versions or veterinary formulations of hydroxyzine. Hydroxyzine HCl comes in tablets or as an oral solution for easier dosing. Human versions also include an oral syrup, but some oral syrups contain alcohol. <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/vistaril\"><span style=\"font-weight: 400;\">Vistaril<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/hydroxyzine-pamoate\"><span style=\"font-weight: 400;\">hydroxyzine pamoate<\/span><\/a><span style=\"font-weight: 400;\">) only comes as capsules. Dosage strengths are too large for cats.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The smallest available dosage strength for hydroxyzine HCl tablets is 10 mg. This is the upper end of the recommended dose. The 10 mg tablets are not usually scored to allow them to be easily broken into smaller doses, so pet parents may need to use an oral solution to give doses smaller than 10 mg.<\/span><\/p>\n<h3 id=\"can-cats-overdose-on-hydroxyzine\"><span style=\"font-weight: 400;\">Can cats overdose on hydroxyzine?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Cats can overdose on hydroxyzine. Call the ASPCA Poison Control Center or an emergency veterinary clinic if a cat has been given too much hydroxyzine.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Symptoms of a hydroxyzine overdose in dogs are well-documented, but there\u2019s little information about how an overdose affects a cat. The most likely signs of a hydroxyzine overdose are sedation and sometimes over-excitement. In dogs, high doses of hydroxyzine can cause tremors, shivering, and sometimes seizures.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Never give a cat more than the prescribed dose or give it more frequently than instructed. In the veterinary medicine literature, the maximum recommended dosage for cats is 10 mg given every 12 hours.<\/span><\/p>\n<h3 id=\"can-i-give-my-cat-hydroxyzine-every-day\"><span style=\"font-weight: 400;\">Can I give my cat hydroxyzine every day?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Hydroxyzine is intended as a symptom-relief medication but is usually used as a long-term preventive therapy. There is no limit on how long a cat can take hydroxyzine. However, cats develop a tolerance for an antihistamine over time. Eventually, continued doses of hydroxyzine will stop working. The veterinarian will probably switch the cat to an antihistamine of a different class.\u00a0<\/span><\/p>\n<h3 id=\"how-to-give-your-cat-hydroxyzine\"><span style=\"font-weight: 400;\">How to give your cat hydroxyzine<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Only give a cat hydroxyzine under the direction of a veterinary professional. When dosing the cat, pet parents have the option of using tablets, oral solution, or oral syrup.<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Follow all the veterinarian\u2019s instructions.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/dogcatdoc.com\/wp-content\/uploads\/2021\/05\/VMG-Hydroxyzine.pdf\"><span style=\"font-weight: 400;\">Cats can take a hydroxyzine dose with or without food<\/span><\/a><span style=\"font-weight: 400;\">. If the cat gets sick after a dose given on an empty stomach, try giving future doses with food.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">If you\u2019re not experienced at administering tablets to your cat, ask a veterinary professional to demonstrate the proper technique.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">If you give the cat an oral syrup or oral solution, use the measuring device that comes with the medicine to measure out doses. The veterinarian can supply an appropriate calibrated measuring device.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">If a dose of hydroxyzine is missed, give it as soon as it\u2019s remembered. If it\u2019s almost time for the next dose, skip the missed dose and give the next dose as scheduled.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Store hydroxyzine tablets, oral solution, and oral syrup in a tightly closed, light-resistant container at room temperature. Do not freeze the liquid versions.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hydroxyzine doses can be stopped at any time without tapering doses.<\/span><\/li>\n<\/ul>\n<h2 id=\"hydroxyzine-alternatives-for-cats\"><span style=\"font-weight: 400;\">Hydroxyzine alternatives for cats<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Hydroxyzine isn\u2019t necessarily a veterinarian\u2019s first choice for itchy skin or sensitivity reactions. The <\/span><a href=\"https:\/\/www.aaha.org\/wp-content\/uploads\/globalassets\/02-guidelines\/2023-aaha-management-of-allergic-skin-diseases-in-dogs-and-cats-guidelines\/resources\/2023-aaha-management-of-allergic-skin-diseases-guidelines.pdf\"><span style=\"font-weight: 400;\">preferred treatments<\/span><\/a><span style=\"font-weight: 400;\"> are:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Corticosteroids such as <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/prednisolone\/what-is\"><span style=\"font-weight: 400;\">prednisolone<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Immune suppressants such as <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/cyclosporine\"><span style=\"font-weight: 400;\">cyclosporine<\/span><\/a><span style=\"font-weight: 400;\"> or oclacitinib<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Allergen-specific immunotherapy<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Essential fatty acids<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/todaysveterinarypractice.com\/dermatology\/feline-atopic-skin-syndrome\/\"><span style=\"font-weight: 400;\">Maropitant<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.dvm360.com\/view\/a-clinical-approach-to-feline-atopic-dermatitis\"><span style=\"font-weight: 400;\">Gabapentin<\/span><\/a><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Veterinarians are more likely to use hydroxyzine or another antihistamine as a preventive treatment for atopy, either before exposure or as a long-term preventive treatment. This helps reduce the cat\u2019s exposure to corticosteroid side effects and complications.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If an antihistamine is appropriate, veterinarians can choose from a variety of antihistamines. Many don\u2019t cause drowsiness to the degree that first-generation antihistamines like hydroxyzine do. One alternative is cetirizine, an active version of hydroxyzine. Better known as brand-name <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/zyrtec\"><span style=\"font-weight: 400;\">Zyrtec<\/span><\/a><span style=\"font-weight: 400;\">, cetirizine doesn\u2019t cross the blood-brain barrier and is less likely to cause drowsiness and depression in a cat. Other antihistamines used in cats include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/chlorpheniramine-maleate\"><span style=\"font-weight: 400;\">Chlorpheniramine<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/cyproheptadine-hcl\"><span style=\"font-weight: 400;\">Cyproheptadine<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/clemastine-fumarate\"><span style=\"font-weight: 400;\">Clemastine<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/loratadine\"><span style=\"font-weight: 400;\">Loratadine<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/fexofenadine-hcl\"><span style=\"font-weight: 400;\">Fexofenadine<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/diphenhydramine-hcl\"><span style=\"font-weight: 400;\">Diphenhydramine<\/span><\/a><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">The antidepressant <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/amitriptyline-hcl\"><span style=\"font-weight: 400;\">amitriptyline<\/span><\/a><span style=\"font-weight: 400;\"> is also a <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39202\/\"><span style=\"font-weight: 400;\">powerful antihistamine<\/span><\/a><span style=\"font-weight: 400;\"> and can be used to treat pruritus in cats.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">One problem with antihistamines is that animals gradually develop tolerance for the drug. They eventually lose their effectiveness. In that case, the veterinarian may need to stop treatment and <\/span><a href=\"https:\/\/veterinarypartner.vin.com\/default.aspx?pid=19239&amp;id=4951437\"><span style=\"font-weight: 400;\">restart with a different class of antihistamine<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h2 id=\"summary\"><span style=\"font-weight: 400;\">Summary<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Antihistamines like hydroxyzine are not commonly used in cats. However, veterinarians can use hydroxyzine for a cat&#8217;s itchy skin or allergic reactions. They typically put cats on hydroxyzine or similar pet medications for long periods as a preventive medicine rather than a symptom reliever.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Hydroxyzine is a prescription antihistamine used to treat contact dermatitis and other allergic reactions in cats. It is safe for cats but is less effective in cats than people. It works best when administered before the cat is exposed to a reaction-inducing event like a vaccine shot. Vets are more likely to use it long-term [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":630308,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[7956],"tags":[15095],"coauthors":[8861],"class_list":["post-630307","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pets","tag-cats","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Hydroxyzine for cats: Dosage and safety<\/title>\n<meta name=\"description\" content=\"Hydroxyzine is used to treat itchy skin and allergic reactions in cats. The standard hydroxyzine dosage for cats is 5\u201310 mg, given every 12 hours.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.singlecare.com\/blog\/hydroxyzine-for-cats\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Can I give my cat hydroxyzine?\" \/>\n<meta property=\"og:description\" content=\"Hydroxyzine is used to treat itchy skin and allergic reactions in cats. 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