{"id":630477,"date":"2024-11-15T18:13:09","date_gmt":"2024-11-15T23:13:09","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=630477"},"modified":"2025-11-11T17:50:56","modified_gmt":"2025-11-11T22:50:56","slug":"enalapril-for-dogs","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/enalapril-for-dogs\/","title":{"rendered":"What is enalapril used for in dogs?"},"content":{"rendered":"<p><a href=\"https:\/\/www.singlecare.com\/prescription\/enalapril-maleate\"><span style=\"font-weight: 400;\">Enalapril<\/span><\/a><span style=\"font-weight: 400;\"> is one of the most commonly used prescription medications to treat canine <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/congestive-heart-failure-treatment-and-medications\"><span style=\"font-weight: 400;\">congestive heart failure<\/span><\/a><span style=\"font-weight: 400;\">, kidney disease, or high blood pressure. All are serious, chronic, and progressive conditions. Enalapril treatment improves the dog\u2019s health, slows the progression of these diseases, and lengthens the dog\u2019s life.\u00a0<\/span><\/p>\n<h2 id=\"what-is-enalapril-used-for-in-dogs\"><span style=\"font-weight: 400;\">What is enalapril used for in dogs?<\/span><\/h2>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/enalapril-maleate\/what-is\"><span style=\"font-weight: 400;\">Enalapril<\/span><\/a><span style=\"font-weight: 400;\"> is a critical treatment for dogs with congestive heart failure or protein-losing kidney diseases (proteinuria), including chronic kidney disease. Enalapril is also a first-choice starting therapy for dogs with high blood pressure.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Enalapril belongs to a family of drugs called angiotensin-converting enzyme inhibitors (<\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/ace-inhibitors\"><span style=\"font-weight: 400;\">ACE inhibitors<\/span><\/a><span style=\"font-weight: 400;\">). It blocks the production of a hormone called angiotensin II, which tightens blood vessels and increases blood pressure. So, enalapril&#8217;s primary effect is to slacken the muscles in blood vessels, widening them and decreasing blood pressure.<\/span><\/p>\n<h3 id=\"congestive-heart-failure\"><span style=\"font-weight: 400;\">Congestive heart failure<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">When a dog develops congestive heart failure (CHF), the heart struggles to pump enough blood throughout the body. This often stems from damaged heart valves that allow blood to leak and pool in the heart. Over time, this can weaken the heart muscle.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Veterinarians typically use three types of medication to manage CHF:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>ACE inhibitors<\/b><span style=\"font-weight: 400;\">, like enalapril, are used to reduce blood pressure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/drug-classes\/diuretics\"><b>Diuretics<\/b><\/a><span style=\"font-weight: 400;\">, such as <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/furosemide\"><span style=\"font-weight: 400;\">furosemide<\/span><\/a><span style=\"font-weight: 400;\">, are used to remove excess fluid<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Positive inotropes<\/b><span style=\"font-weight: 400;\">, like pimobendan, to strengthen heart contractions<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">ACE inhibitors, including enalapril and benazepril, are a first-line treatment. They ease the heart&#8217;s workload by lowering resistance in the arteries, helping the heart pump more efficiently without increasing the heart rate.<\/span><\/p>\n<h3 id=\"proteinuria-and-kidney-disease\"><span style=\"font-weight: 400;\">Proteinuria and kidney disease<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Proteinuria means there&#8217;s too much protein in a dog\u2019s urine, which can be a warning sign of kidney trouble. Kidneys rely on tiny filters called glomeruli. When these filters become damaged\u2014often from high blood pressure\u2014protein leaks into the urine.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">This condition, if left untreated, can progress to kidney failure. Enalapril helps by:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lowering blood pressure in the glomeruli<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Reducing the amount of protein in the urine<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Slowing down kidney damage<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">It&#8217;s a protective treatment that can help preserve kidney function and extend a dog\u2019s life.<\/span><\/p>\n<h3 id=\"high-blood-pressure\"><span style=\"font-weight: 400;\">High blood pressure<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">For dogs with high blood pressure, <\/span><a href=\"https:\/\/todaysveterinarypractice.com\/cardiology\/systemic-hypertension-in-dogs-cats\/\"><span style=\"font-weight: 400;\">ACE inhibitors<\/span><\/a><span style=\"font-weight: 400;\"> such as enalapril or benazepril are often the initial treatment. While they may not lower blood pressure dramatically, they help protect organs from long-term damage.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If enalapril alone doesn&#8217;t meet blood pressure targets, a veterinarian may add another medication or switch to a different type of blood pressure drug.<\/span><\/p>\n<h2 id=\"is-enalapril-safe-for-dogs\"><span style=\"font-weight: 400;\">Is enalapril safe for dogs?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Yes, enalapril is generally safe for dogs. However, it isn&#8217;t recommended for dogs with:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Allergies to ACE inhibitors<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Certain heart conditions, like aortic stenosis<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Veterinarians may also use caution in dogs with low sodium, blood disorders, or those that are pregnant or nursing.<\/span><\/p>\n<h3 id=\"side-effects-of-enalapril-in-dogs\"><span style=\"font-weight: 400;\">Side effects of enalapril in dogs<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The most common side effects of enalapril in dogs are:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Loss of appetite<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diarrhea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Vomiting<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tiredness<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">These adverse effects are nothing to worry about unless they worsen or persist. If they do, contact the dog\u2019s veterinarian.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">More serious but rare side effects include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low blood pressure (hypotension)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Weakness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High potassium<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kidney dysfunction<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hypersensitivity reactions<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Contact a veterinarian if you notice any signs of a possible severe side effect, including:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Rash<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fever<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tiredness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Weakness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Collapse<\/span><\/li>\n<\/ul>\n<h3 id=\"interactions-of-enalapril-with-other-pet-meds\"><span style=\"font-weight: 400;\">Interactions of enalapril with other pet meds<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Enalapril may interact with other medications, including:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Other blood pressure meds (risk of too-low blood pressure)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diuretics<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Insulin or oral diabetes medications (risk of low blood sugar)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">NSAIDs like carprofen (may reduce effectiveness)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Potassium supplements or potassium-sparing diuretics (risk of high potassium)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Always tell your veterinarian about any medications or supplements your dog is taking, including CBD.<\/span><\/p>\n<h2 id=\"enalapril-dosage-for-dogs\"><span style=\"font-weight: 400;\">Enalapril dosage for dogs<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The standard enalapril dosage for dogs is 0.5 mg per kilogram of body weight taken by mouth every 12 or 24 hours.<\/span><\/p>\n<table class=\" singlecare-table\" role=\"table\">\n<thead>\n<tr>\n<th colspan=\"2\">\n<h2 id=\"detailed-enalapril-dosage-chart-for-dogs\"><span style=\"font-weight: 400;\">Detailed enalapril dosage chart for dogs<\/span><\/h2>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><b>Indication<\/b><\/td>\n<td><b>Standard dose<\/b><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Hypertension<\/span><\/td>\n<td><span style=\"font-weight: 400;\">0.5-1 mg\/kg given by mouth twice a day<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Heart failure<\/span><\/td>\n<td><span style=\"font-weight: 400;\">0.5 mg\/kg given by mouth once or twice a day<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Proteinuria<\/span><\/td>\n<td><span style=\"font-weight: 400;\">0.5 mg\/kg given by mouth once or twice a day OR 0.25\u20131 mg\/kg given by mouth once or twice a day<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span style=\"font-weight: 400;\">The FDA has approved enalapril for dogs, but pet parents can use veterinary formulations or human versions. Doses can be given as tablets, oral suspension (liquid), or oil-based liquids.\u00a0<\/span><\/p>\n<h3 id=\"can-dogs-overdose-on-enalapril\"><span style=\"font-weight: 400;\">Can dogs overdose on enalapril?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Yes, an overdose can cause a dangerous drop in blood pressure. If your dog has ingested too much enalapril, contact your veterinarian or the ASPCA Animal Poison Control Center immediately.<\/span><\/p>\n<h3 id=\"can-i-give-my-dog-enalapril-every-day\"><span style=\"font-weight: 400;\">Can I give my dog enalapril every day?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Yes. Enalapril is often prescribed as a long-term medication for chronic conditions. Dogs may take it daily for months or even years. Regular vet checkups help ensure the medication remains safe and effective.<\/span><\/p>\n<h3 id=\"how-to-give-your-dog-enalapril\"><span style=\"font-weight: 400;\">How to give your dog enalapril<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Pet parents can usually expect to give two doses daily, one in the morning and one in the evening. Some vets will prescribe once-daily doses. When giving doses, pet caregivers have a choice between using tablets or liquid versions.<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Only give if prescribed by a vet<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Follow the exact dosage schedule<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Don\u2019t skip doses<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">You can give it with or without food<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Use the syringe or dropper provided for liquid doses<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Shake liquid formulations before use<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Store tablets at room temperature; check storage instructions for liquids<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">If you miss a dose, give it when you remember\u2014unless it\u2019s almost time for the next one.<\/span><\/p>\n<h2 id=\"enalapril-alternatives-for-dogs\"><span style=\"font-weight: 400;\">Enalapril alternatives for dogs<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">If enalapril isn&#8217;t effective or causes side effects, vets may try:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Other ACE inhibitors: benazepril, lisinopril, ramipril, captopril<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Angiotensin receptor blockers (ARBs): telmisartan, losartan, irbesartan<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Other blood pressure meds: amlodipine, spironolactone, thiazide diuretics<\/span><\/li>\n<\/ul>\n<h2 id=\"how-much-does-enalapril-cost\"><span style=\"font-weight: 400;\">How much does enalapril cost?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The average cost of enalapril without insurance is $71 for 30, 20 mg tablets. With a free coupon from SingleCare, the cost can be as low as $9.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\t\t<div id=\"coupon-cta\" class=\"coupon-cta master-template\">\n\t\t\t<p id=\"headline\">Save up to 80% on Enalapril with SingleCare<\/p>\n\t\t\t<p id=\"subheadline\">Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t<div class=\"details-wrap\">\n\t\t\t\t<div class=\"details\">\n\t\t\t\t\tEnalapril 20 mg (30 Tablets)\t\t\t\t<\/div>\n\t\t\t\t<div class=\"address\">\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"api-response\">\n\t\t\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-walmart-nbh-market.svg\" alt=\"Walmart Neighborhood Market\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$9.00<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/enalapril-maleate#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/enalapril-maleate#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-walmart.svg\" alt=\"Walmart Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$9.00<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/enalapril-maleate#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/enalapril-maleate#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/enalapril-maleate#blog-cta\" class=\"coupon-see-all-btn\">See Enalapril prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t<\/span><\/p>\n<h2 id=\"how-to-fill-your-enalapril-prescription-for-your-dog\"><span style=\"font-weight: 400;\">How to fill your enalapril prescription for your dog<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Enalapril is a prescription medication. That means it has to be prescribed by a veterinarian. Once your veterinarian writes or calls in a prescription for enalapril, it can be filled at any regular pharmacy. Your veterinarian may also dispense enalapril from their hospital or have it filled at a veterinary compounding pharmacy.<\/span><\/p>\n<h2 id=\"summary\"><span style=\"font-weight: 400;\">Summary<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Enalapril is a blood-pressure-lowering drug commonly used in dogs. It\u2019s safe, effective, and has minimal side effects when used as directed to treat heart failure, kidney problems, and high blood pressure. Because benazepril treats serious conditions, it is essential to keep all veterinary appointments so the veterinarian can monitor the dog\u2019s progress.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Enalapril is one of the most commonly used prescription medications to treat canine congestive heart failure, kidney disease, or high blood pressure. All are serious, chronic, and progressive conditions. Enalapril treatment improves the dog\u2019s health, slows the progression of these diseases, and lengthens the dog\u2019s life.\u00a0 What is enalapril used for in dogs? Enalapril is [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":630478,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[7956],"tags":[7969],"coauthors":[8861],"class_list":["post-630477","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pets","tag-dogs","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Enalapril for dogs: Dosage and safety<\/title>\n<meta name=\"description\" content=\"Enalapril is used to treat congestive heart failure, kidney disease, and hypertension in dogs. The standard dose is 0.5 mg\/kg, taken orally every 12\u201324 hours.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.singlecare.com\/blog\/enalapril-for-dogs\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"What is enalapril used for in dogs?\" \/>\n<meta property=\"og:description\" content=\"Enalapril is used to treat congestive heart failure, kidney disease, and hypertension in dogs. 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