{"id":630514,"date":"2024-11-19T14:15:31","date_gmt":"2024-11-19T19:15:31","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=630514"},"modified":"2026-01-30T16:32:14","modified_gmt":"2026-01-30T21:32:14","slug":"propranolol-for-tremors","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/propranolol-for-tremors\/","title":{"rendered":"Propranolol for tremors: Efficacy, side effects, cost, and more"},"content":{"rendered":"<p><a href=\"https:\/\/www.singlecare.com\/prescription\/propranolol-hcl\/what-is\"><span style=\"font-weight: 400;\">Propranolol<\/span><\/a><span style=\"font-weight: 400;\"> is a generic <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/beta-blockers\"><span style=\"font-weight: 400;\">beta blocker<\/span><\/a><span style=\"font-weight: 400;\"> sold under the brand names <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/inderal-la\"><span style=\"font-weight: 400;\">Inderal<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/innopran-xl\/what-is\"><span style=\"font-weight: 400;\">InnoPran<\/span><\/a><span style=\"font-weight: 400;\">, and<\/span> <a href=\"https:\/\/www.singlecare.com\/prescription\/hemangeol\/what-is\"><span style=\"font-weight: 400;\">Hemangeol<\/span><\/a><span style=\"font-weight: 400;\">. Beta blockers are most often used to treat <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/hypertension-treatments-and-medications\"><span style=\"font-weight: 400;\">high blood pressure<\/span><\/a><span style=\"font-weight: 400;\">, but propranolol is also <\/span><span style=\"font-weight: 400;\">approved by the Food and Drug Administration (FDA)<\/span><span style=\"font-weight: 400;\"> to treat essential tremor (ET).\u00a0<\/span><span style=\"font-weight: 400;\">Because of its effectiveness in the treatment of ET, propranolol is sometimes prescribed <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/off-label-prescription-drugs\/\"><span style=\"font-weight: 400;\">off-label<\/span><\/a><span style=\"font-weight: 400;\"> to treat shakiness from performance anxiety or <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/anxiety-attack-vs-panic-attack\/\"><span style=\"font-weight: 400;\">panic attacks<\/span><\/a><span style=\"font-weight: 400;\">. Here\u2019s what you need to know about propranolol for treating ET, including the typical dosage and what to expect when taking it.<\/span><\/p>\n<h2 id=\"propranolol-for-tremors-how-it-works\"><span style=\"font-weight: 400;\">Propranolol for tremors: How it works<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">\u201cEssential tremor is a neurological condition characterized by involuntary and rhythmic shaking,\u201d explains Raj Singh, MD, a primary care physician at <\/span><a href=\"https:\/\/healor.com\/\"><span style=\"font-weight: 400;\">HEALOR<\/span><\/a><span style=\"font-weight: 400;\"> in Las Vegas. He says that while this movement disorder usually affects the <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/shaking-hands\/\"><span style=\"font-weight: 400;\">hands<\/span><\/a><span style=\"font-weight: 400;\">, it can also cause head tremors, voice tremors, or shaking of other muscles or upper limbs. Like <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/parkinsons-symptoms\"><span style=\"font-weight: 400;\">Parkinson\u2019s disease<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK499986\/\"><span style=\"font-weight: 400;\">essential tremor is progressive<\/span><\/a><span style=\"font-weight: 400;\">. Unlike Parkinson\u2019s, essential tremor does not cause other types of dysfunction.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Propranolol is <\/span><a href=\"https:\/\/medlineplus.gov\/ency\/article\/000762.htm\"><span style=\"font-weight: 400;\">one of two<\/span><\/a><span style=\"font-weight: 400;\"> available pharmacologic treatment options for ET. The other is <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/primidone\/what-is\"><span style=\"font-weight: 400;\">primidone<\/span><\/a><span style=\"font-weight: 400;\">, an anti-seizure drug. Both drugs <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22013182\/\"><span style=\"font-weight: 400;\">are effective<\/span><\/a><span style=\"font-weight: 400;\"> at <\/span><a href=\"https:\/\/www.nature.com\/articles\/s41525-022-00318-9\"><span style=\"font-weight: 400;\">reducing tremors by about 50%<\/span><\/a><span style=\"font-weight: 400;\"> in most patients, but propranolol is <\/span><a href=\"https:\/\/practicalneurology.com\/articles\/2023-sept-oct\/treatment-of-essential-tremor\"><span style=\"font-weight: 400;\">the first treatment healthcare providers consider<\/span><\/a><span style=\"font-weight: 400;\"> because it is the only one that\u2019s FDA approved for ET. In some cases, a neurologist might prescribe both of these drugs to be taken together. In other cases, <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4985391\"><span style=\"font-weight: 400;\">topiramate<\/span><\/a><span style=\"font-weight: 400;\">\u00a0or <\/span><a href=\"https:\/\/jnnp.bmj.com\/content\/44\/9\/814\"><span style=\"font-weight: 400;\">metoprolol<\/span><\/a><span style=\"font-weight: 400;\">\u00a0might be prescribed along with or instead of <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/propranolol-hcl\"><span style=\"font-weight: 400;\">propranolol<\/span><\/a><span style=\"font-weight: 400;\"> or <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/primidone\"><span style=\"font-weight: 400;\">primidone<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">So, how does propranolol work for tremors? Dr. Singh explains that <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/propranolol-over-the-counter\/\"><span style=\"font-weight: 400;\">propranolol<\/span><\/a><span style=\"font-weight: 400;\"> helps \u201cblock the effects of epinephrine and norepinephrine,\u201d two stress hormones. By doing so, propranolol helps reduce nervous system activity and the appearance of physical shaking.\u00a0<\/span><\/p>\n<h3 id=\"factors-affecting-propranolol-s-effectiveness-for-essential-tremor\"><span style=\"font-weight: 400;\">Factors affecting propranolol\u2019s effectiveness for essential tremor<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Because propranolol blocks the body\u2019s \u201cfight or flight\u201d response and calms nervous system activity, Dr. Singh says propranolol is most useful for patients whose tremors are \u201cinduced by stress or anxiety.\u201d\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Propranolol\u2019s effectiveness also varies depending on the tremors\u2019 characteristics. In general, tremors are defined by two measurements: <\/span><a href=\"https:\/\/www.aafp.org\/pubs\/afp\/issues\/1999\/0315\/p1565.html\"><span style=\"font-weight: 400;\">amplitude and frequency<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Tremor amplitude<\/b><span style=\"font-weight: 400;\"> describes the range of displacement. For instance, a very slight, barely perceptible <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/stop-hand-tremors-naturally\/\"><span style=\"font-weight: 400;\">hand tremor<\/span><\/a><span style=\"font-weight: 400;\"> might be described as \u201cfine\u201d or \u201clow\u201d amplitude. In contrast, forceful shaking that causes the hand to move up and down by a full centimeter might be described as \u201crough\u201d or \u201chigh\u201d amplitude.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Tremor frequency<\/b><span style=\"font-weight: 400;\"> describes the speed of displacement. Essential tremor causes a rhythmic shakiness, but the movement speed varies from person to person.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">A review of clinical trials published in<\/span> <a href=\"https:\/\/www.uspharmacist.com\/article\/essential-tremor-a-common-disorder-with-limited-treatments\"><i><span style=\"font-weight: 400;\">U.S. Pharmacist<\/span><\/i><\/a><span style=\"font-weight: 400;\"> found that propranolol works best for high-amplitude, low-frequency essential tremor. In other words, it offers the most tremor suppression for individuals experiencing forceful, low-speed tremors. Still, the review concluded by stating that the effectiveness of propranolol varies from person to person.\u00a0<\/span><\/p>\n<h2 id=\"how-to-use-propranolol-for-tremors\"><span style=\"font-weight: 400;\">How to use propranolol for tremors<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Essential tremor does not always require treatment because tremors are not always severe enough to affect quality of life. For instance, someone with a limb tremor who can still easily carry on daily activities (like writing, drinking from a glass, and using utensils) might choose not to pursue medical treatment. Once an individual is prescribed propranolol for tremors, it can be taken consistently or on an as-needed basis.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Propranolol dosage varies based on a variety of factors, including symptom severity, age, body size, responsiveness to the drug, and concurrent medications, according to <\/span><a href=\"https:\/\/www.pharmasue.com\/\"><span style=\"font-weight: 400;\">Sue Ojageer, Pharm.D.<\/span><\/a><span style=\"font-weight: 400;\">, founder of <\/span><a href=\"https:\/\/www.pharmacymentors.com\/\"><span style=\"font-weight: 400;\">Pharmacy Mentors<\/span><\/a><span style=\"font-weight: 400;\"> and a <\/span><a href=\"https:\/\/www.singlecare.com\/pharmacy-awards\/winner\/2022-best-pharmacist-influencer\/\"><span style=\"font-weight: 400;\">SingleCare Best of the Best Pharmacy Awards winner<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h3 id=\"consistent-usage\"><span style=\"font-weight: 400;\">Consistent usage<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Propranolol for essential tremor is usually taken by mouth two to three times daily. In general, adults with essential tremor can expect to start with a <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/propranolol-hcl\/dosage\"><span style=\"font-weight: 400;\">dosage<\/span><\/a><span style=\"font-weight: 400;\"> of 40 milligrams (mg) twice per day. \u201cDepending on the individual\u2019s response to treatment and side effects, this can be increased, with many patients stabilizing at a daily dose of 120\u2013240 mg, usually divided into two to three doses throughout the day,\u201d Dr. Ojageer explains. \u201cUltimately, the goal is to start with the lowest effective dose and titrate slowly, balancing symptom control with any potential side effects.\u201d Consistent use of medication helps decrease chronic symptoms in most patients.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The maximum dose for essential tremor is 320 mg of propranolol per day. As is the case with most medications, a higher dose increases the risk of side effects such as lightheadedness, fatigue, nausea, and gastrointestinal distress.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Dosage can also vary depending on the form of propranolol. Dr. Ojageer says extended-release formulations (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/propranolol-hcl-er\"><span style=\"font-weight: 400;\">propranolol ER<\/span><\/a><span style=\"font-weight: 400;\">) are taken just once daily. Propranolol ER is available in 60 mg, 80 mg, 120 mg, and 160 mg capsules. The <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=5c370417-eff0-7280-e053-2a91aa0a1446\"><span style=\"font-weight: 400;\">standard dose<\/span><\/a><span style=\"font-weight: 400;\"> of propranolol ER is 80 mg.<\/span><\/p>\n<h3 id=\"as-needed-usage\"><span style=\"font-weight: 400;\">As-needed usage<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Some individuals only take propranolol as needed. When taken to improve job performance or to reduce performance anxiety, propranolol is usually taken 30\u201360 minutes before the anticipated need for tremor suppression. In that case, dosage may vary. It\u2019s important to stick to the dose or dose range prescribed by your healthcare provider.\u00a0<\/span><\/p>\n<h2 id=\"how-fast-does-propranolol-work-for-tremors\"><span style=\"font-weight: 400;\">How fast does propranolol work for tremors?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">How fast propranolol works for tremors depends on whether an individual takes immediate-release propranolol or long-acting propranolol.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Regular propranolol is an immediate-release medication that usually starts to work within one hour of ingestion. It is fast-acting but must be taken multiple times daily for all-day effectiveness. Standard propranolol has a <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK532906\/\"><span style=\"font-weight: 400;\">four-hour half-life<\/span><\/a><span style=\"font-weight: 400;\">. That means about half of an individual\u2019s dose remains in the body after four hours. Given that, propranolol is most effective within one to four hours after ingestion. Once four hours have passed, the effects begin to wane.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Propranolol extended-release (ER) is a once-daily medication slowly released into the body and intended to last all day. It has a <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2011\/018553s037lbl.pdf\"><span style=\"font-weight: 400;\">half-life of about 10 hours<\/span><\/a><span style=\"font-weight: 400;\">, so it has a more gradual onset with effects lasting up to 24 hours.<\/span><\/p>\n<h2 id=\"propranolol-side-effects-warnings\"><span style=\"font-weight: 400;\">Propranolol side effects &amp; warnings<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Common <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/propranolol-side-effects\/\"><span style=\"font-weight: 400;\">side effects of propranolol<\/span><\/a><span style=\"font-weight: 400;\"> include dizziness, drowsiness, and gastrointestinal issues. In rarer cases, individuals on propranolol experience serious adverse effects such as hallucinations or mood changes. Adverse events are much less common on a low dose.<\/span><\/p>\n<h2 id=\"who-should-not-take-propranolol-for-tremors\"><span style=\"font-weight: 400;\">Who should not take propranolol for tremors?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Propranolol isn\u2019t right for everyone. It is contraindicated (not recommended for use) in certain populations.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u00a0<\/span><span style=\"font-weight: 400;\">According to the FDA-approved label, people with the following health conditions should not take propranolol:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cardiogenic shock<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sinus bradycardia<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Greater than first-degree heart block<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Bronchial asthma<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hypersensitivity to propranolol hydrochloride\u00a0<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">In general, propranolol may not be appropriate for patients with impaired liver or kidney function. As is the case with many medications, people who are pregnant, planning to become pregnant, or breastfeeding should talk to their healthcare provider before taking propranolol.<\/span><\/p>\n<h2 id=\"how-much-does-propranolol-cost\"><span style=\"font-weight: 400;\">How much does propranolol cost?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">\u201cPropranolol is generally covered by most insurance plans for the treatment of essential tremor,\u201d Dr. Ojageer says. \u201cCoverage may vary depending on the specific health insurance plan, as some insurers may require a trial of a generic formulation before approving coverage for brand-name versions or extended-release formulations.\u201d Your copay may also vary based on your dosage, chosen pharmacy, and geographic region.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Individuals <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/propranolol-without-insurance\/\"><span style=\"font-weight: 400;\">without insurance<\/span><\/a><span style=\"font-weight: 400;\"> might need to pay out of pocket for this medication. The <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/propranolol-hcl\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">current retail price of propranolol<\/span><\/a><span style=\"font-weight: 400;\"> is $41 for 60, 10 mg tablets. However, a <\/span><a href=\"https:\/\/www.singlecare.com\/prescription-discount-card\"><span style=\"font-weight: 400;\">SingleCare prescription discount card<\/span><\/a><span style=\"font-weight: 400;\"> can lower the out-of-pocket cost to about $7 for 60, 10 mg tablets.<\/span><\/p>\n<h2 id=\"bottom-line\"><span style=\"font-weight: 400;\">Bottom line<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Propranolol is a beta blocker that is FDA approved for the treatment of essential tremor. On average, propranolol use reduces tremors by about 50%.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The effectiveness of propranolol for essential tremor depends on the underlying cause of the tremors, as well as the amplitude and frequency of shaking. Individuals with essential tremor need to know that it may take time to find the best dosage, as each person responds to propranolol differently. It\u2019s also important to manage expectations because propranolol is not a cure for tremors. It simply reduces symptoms of essential tremor in many cases.<\/span><\/p>\n<p><small><i><span style=\"font-weight: 400;\">The SingleCare prices in this article are the most accurate at the time of publishing in ZIP code 23666 as of <\/span><\/i><i><span style=\"font-weight: 400;\">Jan. 30, 2026<\/span><\/i><i><span style=\"font-weight: 400;\">. Prices vary by pharmacy. Visit our <\/span><\/i><a href=\"https:\/\/www.singlecare.com\/prescription\/propranolol-hcl\"><i><span style=\"font-weight: 400;\">propranolol <\/span><\/i><i><span style=\"font-weight: 400;\">coupon page<\/span><\/i><\/a><i><span style=\"font-weight: 400;\"> for updated prices near you.<\/span><\/i><small><\/small><\/small><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Propranolol is a generic beta blocker sold under the brand names Inderal, InnoPran, and Hemangeol. Beta blockers are most often used to treat high blood pressure, but propranolol is also approved by the Food and Drug Administration (FDA) to treat essential tremor (ET).\u00a0Because of its effectiveness in the treatment of ET, propranolol is sometimes prescribed [&hellip;]<\/p>\n","protected":false},"author":149,"featured_media":630516,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[3418],"coauthors":[20942],"class_list":["post-630514","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-generic-drugs","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Propranolol for tremors: Efficacy, side effects, cost, and more<\/title>\n<meta name=\"description\" content=\"Propranolol is the only FDA-approved treatment for essential tremor, although other drugs may be prescribed off-label. 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