{"id":630721,"date":"2024-12-17T09:30:24","date_gmt":"2024-12-17T14:30:24","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=630721"},"modified":"2025-08-25T18:01:13","modified_gmt":"2025-08-25T22:01:13","slug":"does-mounjaro-need-to-be-refrigerated","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/does-mounjaro-need-to-be-refrigerated\/","title":{"rendered":"Does Mounjaro need to be refrigerated?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Like semaglutide, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/mounjaro\"><span style=\"font-weight: 400;\">Mounjaro<\/span><\/a><span style=\"font-weight: 400;\"> (tirzepatide) is a once-a-week injectable medication that is FDA approved for helping manage blood sugar levels in those with <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/type-2-diabetes-treatment-and-medications\"><span style=\"font-weight: 400;\">Type 2 diabetes<\/span><\/a><span style=\"font-weight: 400;\">. It mimics two gastrointestinal hormones: <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/glp-1-agonists\"><span style=\"font-weight: 400;\">glucagon-like peptide-1 (GLP-1)<\/span><\/a><span style=\"font-weight: 400;\"> and gastric inhibitory polypeptide (GIP). So, the active ingredient can also be prescribed for <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/news\/weight-loss-statistics\/\"><span style=\"font-weight: 400;\">weight loss<\/span><\/a><span style=\"font-weight: 400;\"> or obesity, combined with diet and exercise, under its licensed brand name Zepbound.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">While Mounjaro should be refrigerated to maximize shelf life, that doesn\u2019t need to be a cause for stress if there\u2019s travel in your future. Read along to find out how to safely take Mounjaro with you on vacation, what to do if you accidentally leave your medication outside of the refrigerator, and how hot is too hot for this medication.<\/span><\/p>\n\t\t<div id=\"coupon-cta\" class=\"coupon-cta master-template\">\n\t\t\t<p id=\"headline\">Save up to 80% on Mounjaro with SingleCare<\/p>\n\t\t\t<p id=\"subheadline\">Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t<div class=\"details-wrap\">\n\t\t\t\t<div class=\"details\">\n\t\t\t\t\tMounjaro 5 mg\/0.5 mL (4 pens)\t\t\t\t<\/div>\n\t\t\t\t<div class=\"address\">\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"api-response\">\n\t\t\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-kroger.svg\" alt=\"Kroger Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$872.48<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"#\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"#\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-harristeeter.svg\" alt=\"Harris Teeter Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$872.48<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"#\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"#\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t<a target=\"_blank\" href=\"#\" class=\"coupon-see-all-btn\">See Mounjaro prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n<h2 id=\"does-mounjaro-need-to-be-refrigerated\"><span style=\"font-weight: 400;\">Does Mounjaro need to be refrigerated?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">\u201cIdeally, Mounjaro should be stored at temperatures between <\/span><span style=\"font-weight: 400;\">36 and 46 degrees<\/span><span style=\"font-weight: 400;\"> Fahrenheit,\u201d says <\/span><span style=\"font-weight: 400;\">Tracey Brigman<\/span><span style=\"font-weight: 400;\">, Ed.D., MS, RDN, a clinical associate professor of nutritional sciences at the University of Georgia. While the medication can be left at room temperature for periods of time (more on this later), it will last longer when refrigerated at these temperatures. When placing Mounjaro pens or vials in the refrigerator, it\u2019s best to leave them in their original packaging until use, as they should not be exposed to light, according to the manufacturer&#8217;s instructions.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">It\u2019s important to note that colder isn\u2019t better, however: Mounjaro <\/span><a href=\"https:\/\/my.clevelandclinic.org\/health\/drugs\/23789-tirzepatide-injection\"><span style=\"font-weight: 400;\">should not be frozen<\/span><\/a><span style=\"font-weight: 400;\">. That means extra-cold places like the back of your refrigerator might not be the best place to store your medication. If liquids placed around the edges of your refrigerator tend to freeze, avoid those spaces and opt for a more central location. If you notice that your Mounjaro has frozen, do not use this medication and reach out to a healthcare professional for medical advice.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The refrigerator door can also be a tricky place to store medication. Depending on how often the fridge is opened, door temperatures can fluctuate, leading to warmer-than-expected conditions. (This is the same reason experts <\/span><a href=\"https:\/\/ask.usda.gov\/s\/article\/Is-it-safe-to-store-eggs-in-the-door-of-a-refrigerator\"><span style=\"font-weight: 400;\">advise against<\/span><\/a><span style=\"font-weight: 400;\"> storing eggs, the Goldilocks of fridge staples, in the door of your refrigerator.) In fact, storing Mounjaro near the eggs (not too warm, not too cold) is generally safe and will meet storage requirements.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The final storage location consideration is that all prescription drugs should be kept <\/span><a href=\"https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2765697\"><span style=\"font-weight: 400;\">out of reach<\/span><\/a><span style=\"font-weight: 400;\"> of children. If you have young kids, consider storing medication on a higher shelf that they are unable to access and away from food they typically open the fridge to find, like cheese sticks or juice boxes.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\t\t<div class=\"singlecare-dynamic-newsletter-wrapper sin-newsletter-wrapper\">\n\t\t\t<span class=\"heading\">Get our diabetes newsletter<\/span>\n\t\t\t<form class=\"form-wrapper\" data-newsletter-form=\"1\" data-subsource=\"Diabetes Newsletter\">\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<label for=\"dynamic-email\">Email<\/label>\n\t\t\t\t\t<input type=\"email\" id=\"dynamic-email\" class=\"email\" required>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<input class=\"submit-form-btn\" type=\"submit\" value=\"Click to sign up\">\n\t\t\t\t<\/div>\n\t\t\t<\/form>\n\t\t\t<p class=\"success-message\" aria-live=\"polite\"><\/p>\n\t\t<\/div>\n\t<\/span><\/p>\n<h2 id=\"why-does-mounjaro-need-to-be-refrigerated\"><span style=\"font-weight: 400;\">Why does Mounjaro need to be refrigerated?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">While Mounjaro isn\u2019t the only medication that should be refrigerated, it is one of the more common ones (alongside diabetes and weight loss drugs, such as <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/ozempic\"><span style=\"font-weight: 400;\">Ozempic<\/span><\/a><span style=\"font-weight: 400;\"> and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/zepbound\"><span style=\"font-weight: 400;\">Zepbound<\/span><\/a><span style=\"font-weight: 400;\">). But why is this the recommended method of storage? \u201cThe active ingredient in Mounjaro, <\/span><a href=\"https:\/\/www.mayoclinic.org\/drugs-supplements\/tirzepatide-subcutaneous-route\/description\/drg-20534045\"><span style=\"font-weight: 400;\">tirzepatide<\/span><\/a><span style=\"font-weight: 400;\">, breaks down more quickly at room temperature and becomes less effective over time,\u201d says <a href=\"https:\/\/www.fcs.uga.edu\/people\/bio\/tracey-brigman\">Brigman<\/a>.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cIf medications are not appropriately refrigerated, the chemical structure of the medication can deteriorate and lose its effectiveness for the treatment of diabetes,\u201d adds <\/span><a href=\"https:\/\/hartfordhospital.org\/find-a-doctor\/physician-detail\"><span style=\"font-weight: 400;\">Devika Umashanker<\/span><\/a><span style=\"font-weight: 400;\">, MD, System Director, Medical Weight Loss, with the Hartford HealthCare Digestive Health Institute. That doesn\u2019t mean that you need to inject the medication straight from the refrigerator, however. Many people find it more comfortable to leave their Mounjaro pen on the counter for 30 minutes prior to administering, which is perfectly safe. The temperature of the Mounjaro injection is not known to have an impact on side effects.<\/span><\/p>\n<h2 id=\"how-to-travel-with-mounjaro\"><span style=\"font-weight: 400;\">How to travel with Mounjaro<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Refrigerated medication shouldn\u2019t cause stress during a trip. Whether you use Mounjaro for weight management or another medical condition, with the right knowledge and preparation, travel can be seamless. For starters, don\u2019t travel with more doses of your medication than you expect to need. This will reduce the likelihood that medication is left unrefrigerated unnecessarily.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">For most travel (a quick car ride, a plane trip, etc.), Mounjaro will be safe at room temperature. It\u2019s also important to pack Mounjaro in your carry-on luggage and not your checked luggage. (Don\u2019t worry, prescription medications are <\/span><a href=\"https:\/\/www.tsa.gov\/travel\/tsa-cares\/disabilities-and-medical-conditions\/medications\"><span style=\"font-weight: 400;\">exempt<\/span><\/a><span style=\"font-weight: 400;\"> from TSA liquid regulations.) First, you don\u2019t want your medication to be an accidental casualty of lost baggage. Still, more importantly, the cargo hold where checked baggage is stored during flight is subject to extreme temperatures, making it a less controlled location for medication.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If you\u2019re traveling for an extended period or temperatures may spike <\/span><a href=\"https:\/\/my.clevelandclinic.org\/health\/drugs\/23789-tirzepatide-injection\"><span style=\"font-weight: 400;\">higher than 85 degrees Fahrenheit<\/span><\/a><span style=\"font-weight: 400;\"> during transit, patients can purchase medical boxes that have cooling packs, says Dr. Umashanker. If that\u2019s not an option, cooler bags can also work. It\u2019s important not to store Mounjaro directly next to an ice pack in order to prevent unintentional freezing. Another consideration: Bring something with you that you can use as a sharps container to discard used injection pens.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Finally, we\u2019ve all forgotten to pack items on a trip. If this happens to you and you forget your medication, there are a few steps to follow. \u201cIf you miss a dose while traveling (or for any other reason), take the missed dose as soon as possible within 96 hours (four days). If more than four days have passed, skip the missed dose and resume the next dose on the scheduled day. It is important not to take two doses within three days of each other,\u201d says Brigman.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If you forget to bring your injection pens on an extended trip, contact your healthcare provider and ask what they recommend.<\/span><\/p>\n<h2 id=\"what-to-do-if-mounjaro-is-left-out-of-the-fridge\"><span style=\"font-weight: 400;\">What to do if Mounjaro is left out of the fridge<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Life happens. If your Mounjaro is left outside of the fridge, step one is not to panic. Whether you left your medication on the counter for a few hours or you\u2019re on a two-day road trip to visit family, your Mounjaro is safe as long as it doesn\u2019t reach a temperature of 86 degrees Fahrenheit or remain unrefrigerated for <\/span><a href=\"https:\/\/www.mayoclinic.org\/drugs-supplements\/tirzepatide-subcutaneous-route\/description\/drg-20534045\"><span style=\"font-weight: 400;\">more than 21 days<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cIf you left your Mounjaro out of the refrigerator by accident, it is generally still safe to use if it has not been out of the refrigerator for more than 21 days and the temperature did not go over 86 degrees Fahrenheit,\u201d says Brigman. Once you reach your destination, place your medication back in the refrigerator until you need to travel home. Ensure that it remains out of direct sunlight during transit.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">To avoid complicated math, experts recommend traveling with only the amount of medication required. If you are unsure about whether it is safe to use your medicine, check with your healthcare provider, notes Brigman.<\/span><\/p>\n<h2 id=\"mounjaro-shelf-life\"><span style=\"font-weight: 400;\">Mounjaro shelf life<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">With proper storage conditions, Mounjaro can last up to 24 months, depending on the expiration date, which can be found both on the exterior of the original carton as well as the single-dose pen or vial containing the actual medication.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">With these tips, traveling with medication should be as breezy as the wind off the water. As always, if you have questions or concerns, contact your prescribing healthcare provider for guidance.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Like semaglutide, Mounjaro (tirzepatide) is a once-a-week injectable medication that is FDA approved for helping manage blood sugar levels in those with Type 2 diabetes. It mimics two gastrointestinal hormones: glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP). So, the active ingredient can also be prescribed for weight loss or obesity, combined with diet and [&hellip;]<\/p>\n","protected":false},"author":135,"featured_media":630632,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[10298,788,21067,8905],"coauthors":[12463],"class_list":["post-630721","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-diabetes","tag-drug-safety","tag-glp-1-drugs","tag-seasonal","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Does Mounjaro need to be refrigerated?<\/title>\n<meta name=\"description\" content=\"Learn if Mounjaro, a popular medication for Type 2 diabetes and weight loss, requires refrigeration and how to store it to maintain 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